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Items: 1 to 50 of 326

1.

Enzymatic characteristics of polyphenoloxidase from shrimp (Penaeus vannamei) and its inhibition by a novel hydroxypyridinone derivative.

Shao LL, Zhou JM, Zhu Q, Wang XL, Hider RC, Zhou T.

Food Sci Biotechnol. 2019 Jan 23;28(4):1047-1055. doi: 10.1007/s10068-018-00544-x. eCollection 2019 Aug.

PMID:
31275704
2.

A chemically characterized ethanolic extract of Thai Perilla frutescens (L.) Britton fruits (nutlets) reduces oxidative stress and lipid peroxidation in human hepatoma (HuH7) cells.

Paradee N, Howes MR, Utama-Ang N, Chaikitwattna A, Hider RC, Srichairatanakool S.

Phytother Res. 2019 May 29. doi: 10.1002/ptr.6396. [Epub ahead of print]

PMID:
31141248
3.

Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68Ga chelators for PET imaging.

Imberti C, Chen YL, Foley CA, Ma MT, Paterson BM, Wang Y, Young JD, Hider RC, Blower PJ.

Dalton Trans. 2019 Mar 26;48(13):4299-4313. doi: 10.1039/c8dt04454f.

4.

The Role of Deferiprone in Iron Chelation. Reply.

Hider RC, Hoffbrand AV.

N Engl J Med. 2019 Feb 28;380(9):892-893. doi: 10.1056/NEJMc1817335. No abstract available.

PMID:
30811927
5.

Synthesis and iron chelating properties of hydroxypyridinone and hydroxypyranone hexadentate ligands.

Zhou T, Kong XL, Hider RC.

Dalton Trans. 2019 Mar 5;48(10):3459-3466. doi: 10.1039/c8dt05014g.

PMID:
30793715
6.

The role of mitochondrial labile iron in Friedreich's ataxia skin fibroblasts sensitivity to ultraviolet A.

Reelfs O, Abbate V, Cilibrizzi A, Pook MA, Hider RC, Pourzand C.

Metallomics. 2019 Mar 20;11(3):656-665. doi: 10.1039/c8mt00257f.

7.

The Role of Deferiprone in Iron Chelation.

Hider RC, Hoffbrand AV.

N Engl J Med. 2018 Nov 29;379(22):2140-2150. doi: 10.1056/NEJMra1800219. Review. No abstract available.

PMID:
30485781
8.

Design of Bifunctional Dendritic 5-Aminolevulinic Acid and Hydroxypyridinone Conjugates for Photodynamic Therapy.

Zhou T, Battah S, Mazzacuva F, Hider RC, Dobbin P, MacRobert AJ.

Bioconjug Chem. 2018 Oct 17;29(10):3411-3428. doi: 10.1021/acs.bioconjchem.8b00574. Epub 2018 Oct 5.

9.

Protein-Corona-by-Design in 2D: A Reliable Platform to Decode Bio-Nano Interactions for the Next-Generation Quality-by-Design Nanomedicines.

Mei KC, Ghazaryan A, Teoh EZ, Summers HD, Li Y, Ballesteros B, Piasecka J, Walters A, Hider RC, Mailänder V, Al-Jamal KT.

Adv Mater. 2018 Aug 24:e1802732. doi: 10.1002/adma.201802732. [Epub ahead of print]

PMID:
30144166
10.

Hydroxypyridinone Journey into Metal Chelation.

Cilibrizzi A, Abbate V, Chen YL, Ma Y, Zhou T, Hider RC.

Chem Rev. 2018 Aug 22;118(16):7657-7701. doi: 10.1021/acs.chemrev.8b00254. Epub 2018 Jul 23.

PMID:
30033720
11.

Synthesis, iron binding and antimicrobial properties of hexadentate 3-hydroxypyridinones-terminated dendrimers.

Zhou T, Chen K, Kong LM, Liu MS, Ma YM, Xie YY, Hider RC.

Bioorg Med Chem Lett. 2018 Aug 1;28(14):2504-2512. doi: 10.1016/j.bmcl.2018.05.058. Epub 2018 May 30.

PMID:
29886020
12.

The interaction of pyridoxal isonicotinoyl hydrazone (PIH) and salicylaldehyde isonicotinoyl hydrazone (SIH) with iron.

Chen YL, Kong X, Xie Y, Hider RC.

J Inorg Biochem. 2018 Mar;180:194-203. doi: 10.1016/j.jinorgbio.2017.12.007. Epub 2017 Dec 21.

PMID:
29329026
13.

Ion-Pairing with Spermine Targets Theophylline To the Lungs via the Polyamine Transport System.

Benaouda F, Jones SA, Chana J, Dal Corno BM, Barlow DJ, Hider RC, Page CP, Forbes B.

Mol Pharm. 2018 Mar 5;15(3):861-870. doi: 10.1021/acs.molpharmaceut.7b00715. Epub 2018 Feb 9.

PMID:
29307184
14.

Novel Hyaluronic Acid Conjugates for Dual Nuclear Imaging and Therapy in CD44-Expressing Tumors in Mice In Vivo.

Dubey RD, Klippstein R, Wang JT, Hodgins N, Mei KC, Sosabowski J, Hider RC, Abbate V, Gupta PN, Al-Jamal KT.

Nanotheranostics. 2017 Jan 1;1(1):59-79. doi: 10.7150/ntno.17896. eCollection 2017.

15.

Novel hydroxypyridinone derivatives containing an oxime ether moiety: Synthesis, inhibition on mushroom tyrosinase and application in anti-browning of fresh-cut apples.

Shao LL, Wang XL, Chen K, Dong XW, Kong LM, Zhao DY, Hider RC, Zhou T.

Food Chem. 2018 Mar 1;242:174-181. doi: 10.1016/j.foodchem.2017.09.054. Epub 2017 Sep 12.

PMID:
29037675
16.

Preparation, antioxidant and antimicrobial evaluation of hydroxamated degraded polysaccharides from Enteromorpha prolifera.

Shao LL, Xu J, Shi MJ, Wang XL, Li YT, Kong LM, Hider RC, Zhou T.

Food Chem. 2017 Dec 15;237:481-487. doi: 10.1016/j.foodchem.2017.05.119. Epub 2017 May 24.

PMID:
28764023
17.

Cardioprotective effects of Cu(II)ATSM in human vascular smooth muscle cells and cardiomyocytes mediated by Nrf2 and DJ-1.

Srivastava S, Blower PJ, Aubdool AA, Hider RC, Mann GE, Siow RC.

Sci Rep. 2016 Dec 21;6(1):7. doi: 10.1038/s41598-016-0012-5.

18.

68Ga-THP-PSMA: A PET Imaging Agent for Prostate Cancer Offering Rapid, Room-Temperature, 1-Step Kit-Based Radiolabeling.

Young JD, Abbate V, Imberti C, Meszaros LK, Ma MT, Terry SYA, Hider RC, Mullen GE, Blower PJ.

J Nucl Med. 2017 Aug;58(8):1270-1277. doi: 10.2967/jnumed.117.191882. Epub 2017 Apr 13.

19.

Hydroxypyridinone and 5-Aminolaevulinic Acid Conjugates for Photodynamic Therapy.

Battah S, Hider RC, MacRobert AJ, Dobbin PS, Zhou T.

J Med Chem. 2017 Apr 27;60(8):3498-3510. doi: 10.1021/acs.jmedchem.7b00346. Epub 2017 Apr 6.

PMID:
28363026
20.

Hydroxypyridinone Chelators: From Iron Scavenging to Radiopharmaceuticals for PET Imaging with Gallium-68.

Cusnir R, Imberti C, Hider RC, Blower PJ, Ma MT.

Int J Mol Sci. 2017 Jan 8;18(1). pii: E116. doi: 10.3390/ijms18010116. Review.

21.

Improved antioxidant and anti-tyrosinase activity of polysaccharide from Sargassum fusiforme by degradation.

Chen BJ, Shi MJ, Cui S, Hao SX, Hider RC, Zhou T.

Int J Biol Macromol. 2016 Nov;92:715-722. doi: 10.1016/j.ijbiomac.2016.07.082. Epub 2016 Jul 25.

PMID:
27471085
22.

Design and synthesis of novel hydroxypyridinone derivatives as potential tyrosinase inhibitors.

Zhao DY, Zhang MX, Dong XW, Hu YZ, Dai XY, Wei X, Hider RC, Zhang JC, Zhou T.

Bioorg Med Chem Lett. 2016 Jul 1;26(13):3103-3108. doi: 10.1016/j.bmcl.2016.05.006. Epub 2016 May 4.

PMID:
27185329
23.

A Powerful Mitochondria-Targeted Iron Chelator Affords High Photoprotection against Solar Ultraviolet A Radiation.

Reelfs O, Abbate V, Hider RC, Pourzand C.

J Invest Dermatol. 2016 Aug;136(8):1692-1700. doi: 10.1016/j.jid.2016.03.041. Epub 2016 Apr 22.

24.

Copper(II) binding properties of hepcidin.

Kulprachakarn K, Chen YL, Kong X, Arno MC, Hider RC, Srichairatanakool S, Bansal SS.

J Biol Inorg Chem. 2016 Jun;21(3):329-38. doi: 10.1007/s00775-016-1342-2. Epub 2016 Feb 16.

25.

Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling.

Santos CX, Hafstad AD, Beretta M, Zhang M, Molenaar C, Kopec J, Fotinou D, Murray TV, Cobb AM, Martin D, Zeh Silva M, Anilkumar N, Schröder K, Shanahan CM, Brewer AC, Brandes RP, Blanc E, Parsons M, Belousov V, Cammack R, Hider RC, Steiner RA, Shah AM.

EMBO J. 2016 Feb 1;35(3):319-34. doi: 10.15252/embj.201592394. Epub 2016 Jan 7.

26.

Design and synthesis of novel pegylated iron chelators with decreased metabolic rate.

Li J, Lu Z, Kong X, Ma Y, Zhang X, Bansal SS, Abbate V, Hider RC.

Future Med Chem. 2015;7(18):2439-49. doi: 10.4155/fmc.15.154. Epub 2015 Dec 16.

PMID:
26670054
27.
28.

Dual selective iron chelating probes with a potential to monitor mitochondrial labile iron pools.

Abbate V, Reelfs O, Kong X, Pourzand C, Hider RC.

Chem Commun (Camb). 2016 Jan 14;52(4):784-7. doi: 10.1039/c5cc06170a.

PMID:
26567874
29.

Second international round robin for the quantification of serum non-transferrin-bound iron and labile plasma iron in patients with iron-overload disorders.

de Swart L, Hendriks JC, van der Vorm LN, Cabantchik ZI, Evans PJ, Hod EA, Brittenham GM, Furman Y, Wojczyk B, Janssen MC, Porter JB, Mattijssen VE, Biemond BJ, MacKenzie MA, Origa R, Galanello R, Hider RC, Swinkels DW.

Haematologica. 2016 Jan;101(1):38-45. doi: 10.3324/haematol.2015.133983. Epub 2015 Sep 18.

30.

Synthesis of double-clickable functionalised graphene oxide for biological applications.

Mei KC, Rubio N, Costa PM, Kafa H, Abbate V, Festy F, Bansal SS, Hider RC, Al-Jamal KT.

Chem Commun (Camb). 2015 Oct 18;51(81):14981-4. doi: 10.1039/c5cc05412e.

31.

Iron Deficiency Impairs Intra-Hepatic Lymphocyte Mediated Immune Response.

Bonaccorsi-Riani E, Danger R, Lozano JJ, Martinez-Picola M, Kodela E, Mas-Malavila R, Bruguera M, Collins HL, Hider RC, Martinez-Llordella M, Sanchez-Fueyo A.

PLoS One. 2015 Aug 19;10(8):e0136106. doi: 10.1371/journal.pone.0136106. eCollection 2015.

32.

Solvent-Free Click-Mechanochemistry for the Preparation of Cancer Cell Targeting Graphene Oxide.

Rubio N, Mei KC, Klippstein R, Costa PM, Hodgins N, Wang JT, Festy F, Abbate V, Hider RC, Chan KL, Al-Jamal KT.

ACS Appl Mater Interfaces. 2015 Sep 2;7(34):18920-3. doi: 10.1021/acsami.5b06250. Epub 2015 Aug 20.

33.

Organic Solvent-Free, One-Step Engineering of Graphene-Based Magnetic-Responsive Hybrids Using Design of Experiment-Driven Mechanochemistry.

Mei KC, Guo Y, Bai J, Costa PM, Kafa H, Protti A, Hider RC, Al-Jamal KT.

ACS Appl Mater Interfaces. 2015 Jul 8;7(26):14176-81. doi: 10.1021/acsami.5b03577. Epub 2015 Jun 25.

34.

Design of novel fluorescent mitochondria-targeted peptides with iron-selective sensing activity.

Abbate V, Reelfs O, Hider RC, Pourzand C.

Biochem J. 2015 Aug 1;469(3):357-66. doi: 10.1042/BJ20150149. Epub 2015 May 26.

PMID:
26008950
35.

pFe(3+) determination of multidentate ligands by a fluorescence assay.

Ma Y, Zhou T, Hider RC.

Analyst. 2015 May 21;140(10):3603-6. doi: 10.1039/c5an00123d. Epub 2015 Apr 10.

PMID:
25857340
36.

Hexadentate 3-hydroxypyridin-4-ones with high iron(III) affinity: design, synthesis and inhibition on methicillin resistant Staphylococcus aureus and Pseudomonas strains.

Zhou YJ, Liu MS, Osamah AR, Kong XL, Alsam S, Battah S, Xie YY, Hider RC, Zhou T.

Eur J Med Chem. 2015 Apr 13;94:8-21. doi: 10.1016/j.ejmech.2015.02.050. Epub 2015 Feb 26.

PMID:
25747496
37.

Deferitazole, a new orally active iron chelator.

Hider RC, Kong X, Abbate V, Harland R, Conlon K, Luker T.

Dalton Trans. 2015 Mar 21;44(11):5197-204. doi: 10.1039/c5dt00063g.

PMID:
25687725
38.

Characterisation of a novel oral iron chelator: 1-(N-Acetyl-6-Aminohexyl)-3-Hydroxy-2-Methylpyridin-4-one.

Pangjit K, Banjerdpongchai R, Phisalaphong C, Fucharoen S, Xie YY, Lu ZD, Hider RC, Srichairatanakool S.

J Pharm Pharmacol. 2015 May;67(5):703-13. doi: 10.1111/jphp.12373. Epub 2015 Jan 28.

PMID:
25627251
39.

Mode of iron(III) chelation by hexadentate hydroxypyridinones.

Zhou T, Hider RC, Kong X.

Chem Commun (Camb). 2015 Apr 4;51(26):5614-7. doi: 10.1039/c4cc10339d.

PMID:
25611052
40.

Design, synthesis and biological evaluation of 5-aminolaevulinic acid/3-hydroxypyridinone conjugates as potential photodynamic therapeutical agents.

Zhu CF, Battah S, Kong X, Reeder BJ, Hider RC, Zhou T.

Bioorg Med Chem Lett. 2015 Feb 1;25(3):558-61. doi: 10.1016/j.bmcl.2014.12.018. Epub 2014 Dec 15.

PMID:
25556100
41.

Iron and zinc sensing in cells and the body.

Hider RC, Maret W.

Metallomics. 2015 Feb;7(2):200-1. doi: 10.1039/c4mt90051k. No abstract available.

PMID:
25501865
42.

Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with (89)Zr(4+): comparison with desferrioxamine-B.

Ma MT, Meszaros LK, Paterson BM, Berry DJ, Cooper MS, Ma Y, Hider RC, Blower PJ.

Dalton Trans. 2015 Mar 21;44(11):4884-900. doi: 10.1039/c4dt02978j.

43.

Iron-sensitive fluorescent probes: monitoring intracellular iron pools.

Ma Y, Abbate V, Hider RC.

Metallomics. 2015 Feb;7(2):212-22. doi: 10.1039/c4mt00214h. Review.

PMID:
25315476
44.

Synthesis and characterizations of pyridazine-based iron chelators.

Ma Y, Kong X, Chen YL, Hider RC.

Dalton Trans. 2014 Dec 7;43(45):17120-8. doi: 10.1039/c4dt02687j.

PMID:
25311299
45.

Iron-chelating and anti-lipid peroxidation properties of 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) in long-term iron loading β-thalassemic mice.

Kulprachakarn K, Chansiw N, Pangjit K, Phisalaphong C, Fucharoen S, Hider RC, Santitherakul S, Srichairatanakool S.

Asian Pac J Trop Biomed. 2014 Aug;4(8):663-8. doi: 10.12980/APJTB.4.2014APJTB-2014-0155.

46.

A novel method for non-transferrin-bound iron quantification by chelatable fluorescent beads based on flow cytometry.

Ma Y, Podinovskaia M, Evans PJ, Emma G, Schaible UE, Porter J, Hider RC.

Biochem J. 2014 Nov 1;463(3):351-62. doi: 10.1042/BJ20140795.

PMID:
25093426
47.

Design, synthesis, and antimicrobial evaluation of hexadentate hydroxypyridinones with high iron(III) affinity.

Zhang MX, Zhu CF, Zhou YJ, Kong XL, Hider RC, Zhou T.

Chem Biol Drug Des. 2014 Dec;84(6):659-68. doi: 10.1111/cbdd.12358. Epub 2014 Jun 26.

PMID:
24890019
48.

In vitro antimicrobial activity of hydroxypyridinone hexadentate-based dendrimeric chelators alone and in combination with norfloxacin.

Zhou YJ, Zhang MX, Hider RC, Zhou T.

FEMS Microbiol Lett. 2014 Jun;355(2):124-30. doi: 10.1111/1574-6968.12465. Epub 2014 Jun 3.

49.

Iron: effect of overload and deficiency.

Hider RC, Kong X.

Met Ions Life Sci. 2013;13:229-94. doi: 10.1007/978-94-007-7500-8_8. Review.

PMID:
24470094
50.

Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species.

Arezes J, Costa M, Vieira I, Dias V, Kong XL, Fernandes R, Vos M, Carlsson A, Rikers Y, Porto G, Rangel M, Hider RC, Pinto JP.

PLoS One. 2013 Nov 21;8(11):e79870. doi: 10.1371/journal.pone.0079870. eCollection 2013.

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