Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 211


Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies.

Kroth H, Oden F, Molette J, Schieferstein H, Capotosti F, Mueller A, Berndt M, Schmitt-Willich H, Darmency V, Gabellieri E, Boudou C, Juergens T, Varisco Y, Vokali E, Hickman DT, Tamagnan G, Pfeifer A, Dinkelborg L, Muhs A, Stephens A.

Eur J Nucl Med Mol Imaging. 2019 Jul 1. doi: 10.1007/s00259-019-04397-2. [Epub ahead of print]


Trauma-targeted delivery of tranexamic acid improves hemostasis and survival in rat liver hemorrhage model.

Girish A, Hickman DA, Banerjee A, Luc N, Ma Y, Miyazawa K, Sekhon UDS, Sun M, Huang S, Sen Gupta A.

J Thromb Haemost. 2019 Jun 20. doi: 10.1111/jth.14552. [Epub ahead of print]


An on-chip model of protein paracellular and transcellular permeability in the microcirculation.

Offeddu GS, Haase K, Gillrie MR, Li R, Morozova O, Hickman D, Knutson CG, Kamm RD.

Biomaterials. 2019 Aug;212:115-125. doi: 10.1016/j.biomaterials.2019.05.022. Epub 2019 May 13.


Effect of itraconazole, food, and ethnic origin on the pharmacokinetics of ivosidenib in healthy subjects.

Dai D, Yang H, Nabhan S, Liu H, Hickman D, Liu G, Zacher J, Vutikullird A, Prakash C, Agresta S, Bowden C, Fan B.

Eur J Clin Pharmacol. 2019 Aug;75(8):1099-1108. doi: 10.1007/s00228-019-02673-6. Epub 2019 Apr 23.


Glucocorticoid Induced Leucine Zipper in Lipopolysaccharide Induced Neuroinflammation.

Witek E, Hickman D, Lahiri DK, Srinivasan M.

Front Aging Neurosci. 2019 Jan 25;10:432. doi: 10.3389/fnagi.2018.00432. eCollection 2018.


Effects of Various Commercially Available Enrichment Options on Handling and Chronic Stress Markers in Female ICR Mice.

Peveler JL, Swan MP, Wheeler RR, Boehm CA, Hickman DL.

J Am Assoc Lab Anim Sci. 2019 Mar 1;58(2):119-125. doi: 10.30802/AALAS-JAALAS-17-000103. Epub 2019 Jan 29.


Association of a Care Coordination Model With Health Care Costs and Utilization: The Johns Hopkins Community Health Partnership (J-CHiP).

Berkowitz SA, Parashuram S, Rowan K, Andon L, Bass EB, Bellantoni M, Brotman DJ, Deutschendorf A, Dunbar L, Durso SC, Everett A, Giuriceo KD, Hebert L, Hickman D, Hough DE, Howell EE, Huang X, Lepley D, Leung C, Lu Y, Lyketsos CG, Murphy SME, Novak T, Purnell L, Sylvester C, Wu AW, Zollinger R, Koenig K, Ahn R, Rothman PB, Brown PMC; Johns Hopkins Community Health Partnership (J-CHiP) Team.

JAMA Netw Open. 2018 Nov 2;1(7):e184273. doi: 10.1001/jamanetworkopen.2018.4273.


Discovery of ( R)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4- b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3 H)-one, a Potent and Selective Pim-1/2 Kinase Inhibitor for Hematological Malignancies.

Wang HL, Andrews KL, Booker SK, Canon J, Cee VJ, Chavez F Jr, Chen Y, Eastwood H, Guerrero N, Herberich B, Hickman D, Lanman BA, Laszlo J 3rd, Lee MR, Lipford JR, Mattson B, Mohr C, Nguyen Y, Norman MH, Pettus LH, Powers D, Reed AB, Rex K, Sastri C, Tamayo N, Wang P, Winston JT, Wu B, Wu Q, Wu T, Wurz RP, Xu Y, Zhou Y, Tasker AS.

J Med Chem. 2019 Feb 14;62(3):1523-1540. doi: 10.1021/acs.jmedchem.8b01733. Epub 2019 Jan 17.


Wellbeing of Alcohol-preferring Rats Euthanized with Carbon Dioxide at Very Low and Low Volume Displacement Rates.

Hickman DL.

J Am Assoc Lab Anim Sci. 2019 Jan 1;58(1):78-82. doi: 10.30802/AALAS-JAALAS-18-000004. Epub 2018 Dec 7.


Effects of Music Enrichment on Individually Housed Male New Zealand White Rabbits.

Peveler JL, Hickman DL.

J Am Assoc Lab Anim Sci. 2018 Oct 25. doi: 10.30802/AALAS-JAALAS-17-000153. [Epub ahead of print]


Characterization and Etiology of Swollen Muzzles in Irradiated Mice.

Garrett J, Sampson CH, Plett PA, Crisler R, Parker J, Venezia R, Chua HL, Hickman DL, Booth C, MacVittie T, Orschell CM, Dynlacht JR.

Radiat Res. 2019 Jan;191(1):31-42. doi: 10.1667/RR14724.1. Epub 2018 Oct 19.


Nuclear factor-kappa B: Glucocorticoid-induced leucine zipper interface analogs suppress pathology in an Alzheimer's disease model.

Srinivasan M, Lahiri N, Thyagarajan A, Witek E, Hickman D, Lahiri DK.

Alzheimers Dement (N Y). 2018 May 24;4:488-498. doi: 10.1016/j.trci.2018.04.004. eCollection 2018.


Home Cage Compared with Induction Chamber for Euthanasia of Laboratory Rats.

Hickman DL.

J Am Assoc Lab Anim Sci. 2018 Oct 10. doi: 10.30802/AALAS-JAALAS-17-000160. [Epub ahead of print]


Interpreting Neuroendocrine Hormones, Corticosterone, and Blood Glucose to Assess the Wellbeing of Anesthetized Rats during Euthanasia.

Hickman DL.

J Am Assoc Lab Anim Sci. 2018 Oct 10. doi: 10.30802/AALAS-JAALAS-17-000159. [Epub ahead of print]


Implementation of a comprehensive program to improve coordination of care in an urban academic health care system.

Hsiao YL, Bass EB, Wu AW, Richardson MB, Deutschendorf A, Brotman DJ, Bellantoni M, Howell EE, Everett A, Hickman D, Purnell L, Zollinger R, Sylvester C, Lyketsos CG, Dunbar L, Berkowitz SA; on behalf of the J-CHiP program .

J Health Organ Manag. 2018 Aug 20;32(5):638-657. doi: 10.1108/JHOM-09-2017-0228. Epub 2018 Aug 10.


Engineering Intravenously Administered Nanoparticles to Reduce Infusion Reaction and Stop Bleeding in a Large Animal Model of Trauma.

Onwukwe C, Maisha N, Holland M, Varley M, Groynom R, Hickman D, Uppal N, Shoffstall A, Ustin J, Lavik E.

Bioconjug Chem. 2018 Jul 18;29(7):2436-2447. doi: 10.1021/acs.bioconjchem.8b00335. Epub 2018 Jul 9.


Small Animal Enclosures and Housing.

Hickman DL, Hickman-Davis JM, Peveler J, Swan M.

In: Weichbrod RH, Thompson GAH, Norton JN, editors. Management of Animal Care and Use Programs in Research, Education, and Testing. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 21.


Development of a step-down method for altering male C57BL/6 mouse housing density and hierarchical structure: Preparations for spaceflight studies.

Scofield DC, Rytlewski JD, Childress P, Shah K, Tucker A, Khan F, Peveler J, Li D, McKinley TO, Chu TG, Hickman DL, Kacena MA.

Life Sci Space Res (Amst). 2018 May;17:44-50. doi: 10.1016/j.lssr.2018.03.002. Epub 2018 Mar 7.


Cohousing Male Mice with and without Segmental Bone Defects.

Rytlewski JD, Childress PJ, Scofield DC, Khan F, Alvarez MB, Tucker AT, Harris JS, Peveler JL, Hickman DL, Chu TG, Kacena MA.

Comp Med. 2018 Apr 2;68(2):131-138.


Intravenous administration of synthetic platelets (SynthoPlate) in a mouse liver injury model of uncontrolled hemorrhage improves hemostasis.

Dyer MR, Hickman D, Luc N, Haldeman S, Loughran P, Pawlowski C, Sen Gupta A, Neal MD.

J Trauma Acute Care Surg. 2018 Jun;84(6):917-923. doi: 10.1097/TA.0000000000001893.


Intravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve 'golden hour' survival in a porcine model of traumatic arterial hemorrhage.

Hickman DA, Pawlowski CL, Shevitz A, Luc NF, Kim A, Girish A, Marks J, Ganjoo S, Huang S, Niedoba E, Sekhon UDS, Sun M, Dyer M, Neal MD, Kashyap VS, Sen Gupta A.

Sci Rep. 2018 Feb 15;8(1):3118. doi: 10.1038/s41598-018-21384-z.


Biomaterials and Advanced Technologies for Hemostatic Management of Bleeding.

Hickman DA, Pawlowski CL, Sekhon UDS, Marks J, Gupta AS.

Adv Mater. 2018 Jan;30(4). doi: 10.1002/adma.201700859. Epub 2017 Nov 22. Review.



Hickman DP, Collins L, Franck D, Harding RN, Jeffers KL, López Ponte MA, Tai LI.

Radiat Prot Dosimetry. 2018 Jan 1;178(2):152-159. doi: 10.1093/rpd/ncx094.


Review of CO₂ as a Euthanasia Agent for Laboratory Rats and Mice.

Boivin GP, Hickman DL, Creamer-Hente MA, Pritchett-Corning KR, Bratcher NA.

J Am Assoc Lab Anim Sci. 2017 Sep 1;56(5):491-499. Review.


Tumor necrosis factor alpha secreted from oral squamous cell carcinoma contributes to cancer pain and associated inflammation.

Scheff NN, Ye Y, Bhattacharya A, MacRae J, Hickman DN, Sharma AK, Dolan JC, Schmidt BL.

Pain. 2017 Dec;158(12):2396-2409. doi: 10.1097/j.pain.0000000000001044.


Evaluation of the neutrophil:lymphocyte ratio as an indicator of chronic distress in the laboratory mouse.

Hickman DL.

Lab Anim (NY). 2017 Jun 23;46(7):303-307. doi: 10.1038/laban.1298.


Effects of daily restraint with and without injections on skeletal properties in C57BL/6NHsd mice.

Larsen RA, Peveler JL, Klutzke JB, Hickman DL, Aref MW, Wallace JM, Brown DM, Allen MR.

Lab Anim (NY). 2017 Jun 23;46(7):299-301. doi: 10.1038/laban.1295. No abstract available.


Development of 2-aminooxazoline 3-azaxanthene β-amyloid cleaving enzyme (BACE) inhibitors with improved selectivity against Cathepsin D.

Low JD, Bartberger MD, Chen K, Cheng Y, Fielden MR, Gore V, Hickman D, Liu Q, Allen Sickmier E, Vargas HM, Werner J, White RD, Whittington DA, Wood S, Minatti AE.

Medchemcomm. 2017 Apr 27;8(6):1196-1206. doi: 10.1039/c7md00106a. eCollection 2017 Jun 1.


Platelet microparticle-inspired clot-responsive nanomedicine for targeted fibrinolysis.

Pawlowski CL, Li W, Sun M, Ravichandran K, Hickman D, Kos C, Kaur G, Sen Gupta A.

Biomaterials. 2017 Jun;128:94-108. doi: 10.1016/j.biomaterials.2017.03.012. Epub 2017 Mar 14.


Discovery and characterization of novel indole and 7-azaindole derivatives as inhibitors of β-amyloid-42 aggregation for the treatment of Alzheimer's disease.

Sreenivasachary N, Kroth H, Benderitter P, Hamel A, Varisco Y, Hickman DT, Froestl W, Pfeifer A, Muhs A.

Bioorg Med Chem Lett. 2017 Mar 15;27(6):1405-1411. doi: 10.1016/j.bmcl.2017.02.001. Epub 2017 Feb 4.


Novel Phospho-Tau Monoclonal Antibody Generated Using a Liposomal Vaccine, with Enhanced Recognition of a Conformational Tauopathy Epitope.

Theunis C, Adolfsson O, Crespo-Biel N, Piorkowska K, Pihlgren M, Hickman DT, Gafner V, Borghgraef P, Devijver H, Pfeifer A, Van Leuven F, Muhs A.

J Alzheimers Dis. 2017;56(2):585-599. doi: 10.3233/JAD-160695.


In vitro characterization of SynthoPlate™ (synthetic platelet) technology and its in vivo evaluation in severely thrombocytopenic mice.

Shukla M, Sekhon UD, Betapudi V, Li W, Hickman DA, Pawlowski CL, Dyer MR, Neal MD, McCrae KR, Sen Gupta A.

J Thromb Haemost. 2017 Feb;15(2):375-387. doi: 10.1111/jth.13579.


Facilitators and Barriers to Implementing Church-Based Adolescent Sexual Health Programs in Baltimore City.

Powell TW, Weeks FH, Illangasekare S, Rice E, Wilson J, Hickman D, Blum RW.

J Adolesc Health. 2017 Feb;60(2):169-175. doi: 10.1016/j.jadohealth.2016.09.017. Epub 2016 Nov 23.


Use of the Phadebas amylase test to assess the presence of rodent saliva.

Prakash A, Lewis SE, Hickman DL.

Lab Anim (NY). 2016 Oct 20;45(11):433-434. doi: 10.1038/laban.1134. No abstract available.


Combination of Adt-O1Manisa and Ad5-boIFNλ3 induces early protective immunity against foot-and-mouth disease in cattle.

Diaz-San Segundo F, Montiel NA, Sturza DF, Perez-Martin E, Hickman D, Ramirez-Medina E, Grubman MJ, de Los Santos T.

Virology. 2016 Dec;499:340-349. doi: 10.1016/j.virol.2016.09.027. Epub 2016 Oct 12.


Case Study: Johns Hopkins Community Health Partnership: A model for transformation.

Berkowitz SA, Brown P, Brotman DJ, Deutschendorf A, Dunbar L, Everett A, Hickman D, Howell E, Purnell L, Sylvester C, Zollinger R, Bellantoni M, Durso SC, Lyketsos C, Rothman P; J-CHiP Program.

Healthc (Amst). 2016 Dec;4(4):264-270. doi: 10.1016/j.hjdsi.2016.09.001. Epub 2016 Sep 29.


Building a Community - Academic Partnership to Enhance Hepatitis C Virus Screening.

Irvin R, McAdams-Mahmoud A, Hickman D, Wilson J, Fenwick W, Chen I, Irvin N, Falade-Nwulia O, Sulkowski M, Chaisson R, Thomas DL, Mehta SH.

J Community Med Health Educ. 2016 Jun;6(3). pii: 431. Epub 2016 May 30.


Evaluation of Low versus High Volume per Minute Displacement CO₂ Methods of Euthanasia in the Induction and Duration of Panic-Associated Behavior and Physiology.

Hickman DL, Fitz SD, Bernabe CS, Caliman IF, Haulcomb MM, Federici LM, Shekhar A, Johnson PL.

Animals (Basel). 2016 Aug 2;6(8). pii: E45. doi: 10.3390/ani6080045.


Reaching for Health Equity and Social Justice in Baltimore: The Evolution of an Academic-Community Partnership and Conceptual Framework to Address Hypertension Disparities.

Cooper LA, Purnell TS, Ibe CA, Halbert JP, Bone LR, Carson KA, Hickman D, Simmons M, Vachon A, Robb I, Martin-Daniels M, Dietz KB, Golden SH, Crews DC, Hill-Briggs F, Marsteller JA, Boulware LE, Miller ER, Levine DM.

Ethn Dis. 2016 Jul 21;26(3):369-78. doi: 10.18865/ed.26.3.369.


Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors.

Pettus LH, Andrews KL, Booker SK, Chen J, Cee VJ, Chavez F Jr, Chen Y, Eastwood H, Guerrero N, Herberich B, Hickman D, Lanman BA, Laszlo J 3rd, Lee MR, Lipford JR, Mattson B, Mohr C, Nguyen Y, Norman MH, Powers D, Reed AB, Rex K, Sastri C, Tamayo N, Wang P, Winston JT, Wu B, Wu T, Wurz RP, Xu Y, Zhou Y, Tasker AS, Wang HL.

J Med Chem. 2016 Jul 14;59(13):6407-30. doi: 10.1021/acs.jmedchem.6b00610. Epub 2016 Jun 22.


Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors.

Cee VJ, Chavez F Jr, Herberich B, Lanman BA, Pettus LH, Reed AB, Wu B, Wurz RP, Andrews KL, Chen J, Hickman D, Laszlo J 3rd, Lee MR, Guerrero N, Mattson BK, Nguyen Y, Mohr C, Rex K, Sastri CE, Wang P, Wu Q, Wu T, Xu Y, Zhou Y, Winston JT, Lipford JR, Tasker AS, Wang HL.

ACS Med Chem Lett. 2016 Feb 12;7(4):408-12. doi: 10.1021/acsmedchemlett.5b00403. eCollection 2016 Apr 14.


An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.

Belichenko PV, Madani R, Rey-Bellet L, Pihlgren M, Becker A, Plassard A, Vuillermot S, Giriens V, Nosheny RL, Kleschevnikov AM, Valletta JS, Bengtsson SK, Linke GR, Maloney MT, Hickman DT, Reis P, Granet A, Mlaki D, Lopez-Deber MP, Do L, Singhal N, Masliah E, Pearn ML, Pfeifer A, Muhs A, Mobley WC.

PLoS One. 2016 Mar 29;11(3):e0152471. doi: 10.1371/journal.pone.0152471. eCollection 2016.


Norovirus antagonism of B-cell antigen presentation results in impaired control of acute infection.

Zhu S, Jones MK, Hickman D, Han S, Reeves W, Karst SM.

Mucosal Immunol. 2016 Nov;9(6):1559-1570. doi: 10.1038/mi.2016.15. Epub 2016 Mar 23.


Bringing Evidence-Based Sexual Health Programs to Adolescents in Black Churches: Applying Knowledge From Systematic Adaptation Frameworks.

Weeks FH, Powell TW, Illangasekare S, Rice E, Wilson J, Hickman D, Blum RW.

Health Educ Behav. 2016 Dec;43(6):699-704. Epub 2016 Mar 8.


Microwave, r0 Structural Parameters, Conformational Stability, and Vibrational Assignment of (Chloromethyl)fluorosilane.

Guirgis GA, Sawant DK, Brenner RE, Deodhar BS, Seifert NA, Geboes Y, Pate BH, Herrebout WA, Hickman DV, Durig JR.

J Phys Chem A. 2015 Nov 25;119(47):11532-47. doi: 10.1021/acs.jpca.5b06679. Epub 2015 Nov 13.


Chronic disease must be confronted on two fronts.

Hickman D.

Aust J Rural Health. 2015 Oct;23(5):310. doi: 10.1111/ajr.12246. No abstract available.


Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors.

Wurz RP, Pettus LH, Ashton K, Brown J, Chen JJ, Herberich B, Hong FT, Hu-Harrington E, Nguyen T, St Jean DJ Jr, Tadesse S, Bauer D, Kubryk M, Zhan J, Cooke K, Mitchell P, Andrews KL, Hsieh F, Hickman D, Kalyanaraman N, Wu T, Reid DL, Lobenhofer EK, Andrews DA, Everds N, Guzman R, Parsons AT, Hedley SJ, Tedrow J, Thiel OR, Potter M, Radinsky R, Beltran PJ, Tasker AS.

ACS Med Chem Lett. 2015 Jul 27;6(9):987-92. doi: 10.1021/acsmedchemlett.5b00193. eCollection 2015 Sep 10.


Pathology in Practice. Mammary tubulopapillary adenocarcinoma in a rabbit.

Ambery AG, Cary C, Hickman DL, Blickman A, Roberts CS.

J Am Vet Med Assoc. 2015 Aug 1;247(3):251-3. doi: 10.2460/javma.247.3.251. No abstract available.


Quality testing of autoclaved rodent drinking water during short-term and long-term storage.

Peveler JL, Crisler R, Hickman D.

Lab Anim (NY). 2015 Jun;44(6):211-5. doi: 10.1038/laban.734.


Supplemental Content

Loading ...
Support Center