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Items: 1 to 20 of 221

1.

Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.

Roboz GJ, DiNardo CD, Stein EM, de Botton S, Mims AS, Prince GT, Altman JK, Arellano ML, Donnellan W, Erba HP, Mannis GN, Pollyea DA, Stein AS, Uy GL, Watts JM, Fathi AT, Kantarjian HM, Tallman MS, Choe S, Dai D, Fan B, Wang H, Zhang V, Yen KE, Kapsalis SM, Hickman D, Liu H, Agresta SV, Wu B, Attar EC, Stone RM.

Blood. 2019 Dec 16. pii: blood.2019002140. doi: 10.1182/blood.2019002140. [Epub ahead of print]

2.

Should radiologists care about kV? Phantom and clinical study of effects of kV on hemoperitoneum HU in the setting of splenic injuries.

Hickman D, Zhang J, McQuerry K, Lee J.

Emerg Radiol. 2019 Nov 26. doi: 10.1007/s10140-019-01738-4. [Epub ahead of print]

PMID:
31773437
3.

Hypertension Self-management in Socially Disadvantaged African Americans: the Achieving Blood Pressure Control Together (ACT) Randomized Comparative Effectiveness Trial.

Boulware LE, Ephraim PL, Hill-Briggs F, Roter DL, Bone LR, Wolff JL, Lewis-Boyer L, Levine DM, Greer RC, Crews DC, Gudzune KA, Albert MC, Ramamurthi HC, Ameling JM, Davenport CA, Lee HJ, Pendergast JF, Wang NY, Carson KA, Sneed V, Gayles DJ, Flynn SJ, Monroe D, Hickman D, Purnell L, Simmons M, Fisher A, DePasquale N, Charleston J, Aboutamar HJ, Cabacungan AN, Cooper LA.

J Gen Intern Med. 2020 Jan;35(1):142-152. doi: 10.1007/s11606-019-05396-7. Epub 2019 Nov 8.

PMID:
31705466
4.

Discovery of AM-6494: A Potent and Orally Efficacious β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2.

Pettus LH, Bourbeau MP, Bradley J, Bartberger MD, Chen K, Hickman D, Johnson M, Liu Q, Manning JR, Nanez A, Siegmund AC, Wen PH, Whittington DA, Allen JR, Wood S.

J Med Chem. 2019 Oct 18. doi: 10.1021/acs.jmedchem.9b01034. [Epub ahead of print]

PMID:
31589043
5.

Application of Transmural Flow Across In Vitro Microvasculature Enables Direct Sampling of Interstitial Therapeutic Molecule Distribution.

Offeddu GS, Possenti L, Loessberg-Zahl JT, Zunino P, Roberts J, Han X, Hickman D, Knutson CG, Kamm RD.

Small. 2019 Nov;15(46):e1902393. doi: 10.1002/smll.201902393. Epub 2019 Sep 9.

PMID:
31497931
6.

Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species.

Foti RS, Biswas K, Aral J, Be X, Berry L, Cheng Y, Conner K, Falsey JR, Glaus C, Herberich B, Hickman D, Ikotun T, Li H, Long J, Huang L, Miranda LP, Murray J, Moyer B, Netirojjanakul C, Nixey TE, Sham K, Soto M, Tegley CM, Tran L, Wu B, Yin L, Rock DA.

Drug Metab Dispos. 2019 Oct;47(10):1111-1121. doi: 10.1124/dmd.119.087742. Epub 2019 Aug 6.

PMID:
31387871
7.

Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies.

Kroth H, Oden F, Molette J, Schieferstein H, Capotosti F, Mueller A, Berndt M, Schmitt-Willich H, Darmency V, Gabellieri E, Boudou C, Juergens T, Varisco Y, Vokali E, Hickman DT, Tamagnan G, Pfeifer A, Dinkelborg L, Muhs A, Stephens A.

Eur J Nucl Med Mol Imaging. 2019 Sep;46(10):2178-2189. doi: 10.1007/s00259-019-04397-2. Epub 2019 Jul 1.

8.

Trauma-targeted delivery of tranexamic acid improves hemostasis and survival in rat liver hemorrhage model.

Girish A, Hickman DA, Banerjee A, Luc N, Ma Y, Miyazawa K, Sekhon UDS, Sun M, Huang S, Sen Gupta A.

J Thromb Haemost. 2019 Oct;17(10):1632-1644. doi: 10.1111/jth.14552. Epub 2019 Jul 15.

PMID:
31220416
9.

An on-chip model of protein paracellular and transcellular permeability in the microcirculation.

Offeddu GS, Haase K, Gillrie MR, Li R, Morozova O, Hickman D, Knutson CG, Kamm RD.

Biomaterials. 2019 Aug;212:115-125. doi: 10.1016/j.biomaterials.2019.05.022. Epub 2019 May 13.

PMID:
31112823
10.

Effect of itraconazole, food, and ethnic origin on the pharmacokinetics of ivosidenib in healthy subjects.

Dai D, Yang H, Nabhan S, Liu H, Hickman D, Liu G, Zacher J, Vutikullird A, Prakash C, Agresta S, Bowden C, Fan B.

Eur J Clin Pharmacol. 2019 Aug;75(8):1099-1108. doi: 10.1007/s00228-019-02673-6. Epub 2019 Apr 23.

PMID:
31011758
11.

Glucocorticoid Induced Leucine Zipper in Lipopolysaccharide Induced Neuroinflammation.

Witek E, Hickman D, Lahiri DK, Srinivasan M.

Front Aging Neurosci. 2019 Jan 25;10:432. doi: 10.3389/fnagi.2018.00432. eCollection 2018.

12.

Effects of Various Commercially Available Enrichment Options on Handling and Chronic Stress Markers in Female ICR Mice.

Peveler JL, Swan MP, Wheeler RR, Boehm CA, Hickman DL.

J Am Assoc Lab Anim Sci. 2019 Mar 1;58(2):119-125. doi: 10.30802/AALAS-JAALAS-17-000103. Epub 2019 Jan 29.

13.

Association of a Care Coordination Model With Health Care Costs and Utilization: The Johns Hopkins Community Health Partnership (J-CHiP).

Berkowitz SA, Parashuram S, Rowan K, Andon L, Bass EB, Bellantoni M, Brotman DJ, Deutschendorf A, Dunbar L, Durso SC, Everett A, Giuriceo KD, Hebert L, Hickman D, Hough DE, Howell EE, Huang X, Lepley D, Leung C, Lu Y, Lyketsos CG, Murphy SME, Novak T, Purnell L, Sylvester C, Wu AW, Zollinger R, Koenig K, Ahn R, Rothman PB, Brown PMC; Johns Hopkins Community Health Partnership (J-CHiP) Team.

JAMA Netw Open. 2018 Nov 2;1(7):e184273. doi: 10.1001/jamanetworkopen.2018.4273.

14.

Discovery of ( R)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4- b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3 H)-one, a Potent and Selective Pim-1/2 Kinase Inhibitor for Hematological Malignancies.

Wang HL, Andrews KL, Booker SK, Canon J, Cee VJ, Chavez F Jr, Chen Y, Eastwood H, Guerrero N, Herberich B, Hickman D, Lanman BA, Laszlo J 3rd, Lee MR, Lipford JR, Mattson B, Mohr C, Nguyen Y, Norman MH, Pettus LH, Powers D, Reed AB, Rex K, Sastri C, Tamayo N, Wang P, Winston JT, Wu B, Wu Q, Wu T, Wurz RP, Xu Y, Zhou Y, Tasker AS.

J Med Chem. 2019 Feb 14;62(3):1523-1540. doi: 10.1021/acs.jmedchem.8b01733. Epub 2019 Jan 17.

PMID:
30624936
15.

Wellbeing of Alcohol-preferring Rats Euthanized with Carbon Dioxide at Very Low and Low Volume Displacement Rates.

Hickman DL.

J Am Assoc Lab Anim Sci. 2019 Jan 1;58(1):78-82. doi: 10.30802/AALAS-JAALAS-18-000004. Epub 2018 Dec 7.

16.

Effects of Music Enrichment on Individually Housed Male New Zealand White Rabbits.

Peveler JL, Hickman DL.

J Am Assoc Lab Anim Sci. 2018 Oct 25. doi: 10.30802/AALAS-JAALAS-17-000153. [Epub ahead of print]

17.

Characterization and Etiology of Swollen Muzzles in Irradiated Mice.

Garrett J, Sampson CH, Plett PA, Crisler R, Parker J, Venezia R, Chua HL, Hickman DL, Booth C, MacVittie T, Orschell CM, Dynlacht JR.

Radiat Res. 2019 Jan;191(1):31-42. doi: 10.1667/RR14724.1. Epub 2018 Oct 19.

PMID:
30339056
18.

Nuclear factor-kappa B: Glucocorticoid-induced leucine zipper interface analogs suppress pathology in an Alzheimer's disease model.

Srinivasan M, Lahiri N, Thyagarajan A, Witek E, Hickman D, Lahiri DK.

Alzheimers Dement (N Y). 2018 May 24;4:488-498. doi: 10.1016/j.trci.2018.04.004. eCollection 2018.

19.

Home Cage Compared with Induction Chamber for Euthanasia of Laboratory Rats.

Hickman DL.

J Am Assoc Lab Anim Sci. 2018 Oct 10. doi: 10.30802/AALAS-JAALAS-17-000160. [Epub ahead of print]

20.

Interpreting Neuroendocrine Hormones, Corticosterone, and Blood Glucose to Assess the Wellbeing of Anesthetized Rats during Euthanasia.

Hickman DL.

J Am Assoc Lab Anim Sci. 2018 Oct 10. doi: 10.30802/AALAS-JAALAS-17-000159. [Epub ahead of print]

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