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The synthesis of isotopologues of AZD7307: A selective β2 -adrenoreceptor agonist.

Kingston LP, Hickey MJ, Elmore CS.

J Labelled Comp Radiopharm. 2019 Jun 19. doi: 10.1002/jlcr.3778. [Epub ahead of print]


Memory regulatory T cells home to the lung and control influenza A virus infection.

Lu C, Zanker D, Lock P, Jiang X, Deng J, Duan M, Liu C, Faou P, Hickey MJ, Chen W.

Immunol Cell Biol. 2019 May 22. doi: 10.1111/imcb.12271. [Epub ahead of print]


Idea2Data: Toward a New Paradigm for Drug Discovery.

Nicolaou CA, Humblet C, Hu H, Martin EM, Dorsey FC, Castle TM, Burton KI, Hu H, Hendle J, Hickey MJ, Duerksen J, Wang J, Erickson JA.

ACS Med Chem Lett. 2019 Feb 4;10(3):278-286. doi: 10.1021/acsmedchemlett.8b00488. eCollection 2019 Mar 14.


Synthesis of di-docosahexaenoyl (C22:6)-bis(monoacylglycerol) phosphate in unlabelled and C-13 labelled forms for use as a biomarker of drug induced phospholipidosis.

Hickey MJ, Lindqvist J, Ha YH, Andersson H, Elmore CS.

J Labelled Comp Radiopharm. 2019 Feb 21. doi: 10.1002/jlcr.3714. [Epub ahead of print]


Platelet retention in inflamed glomeruli occurs via selective prolongation of interactions with immune cells.

Finsterbusch M, Norman MU, Hall P, Kitching AR, Hickey MJ.

Kidney Int. 2019 Feb;95(2):363-374. doi: 10.1016/j.kint.2018.08.042. Epub 2018 Dec 3.


The Many and Varied Roles of Tetraspanins in Immune Cell Recruitment and Migration.

Yeung L, Hickey MJ, Wright MD.

Front Immunol. 2018 Jul 18;9:1644. doi: 10.3389/fimmu.2018.01644. eCollection 2018. Review.


Invariant Natural Killer T Cells Shape the Gut Microbiota and Regulate Neutrophil Recruitment and Function During Intestinal Inflammation.

Shen S, Prame Kumar K, Stanley D, Moore RJ, Van TTH, Wen SW, Hickey MJ, Wong CHY.

Front Immunol. 2018 May 7;9:999. doi: 10.3389/fimmu.2018.00999. eCollection 2018.


Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.

Lau A, Chung H, Komada T, Platnich JM, Sandall CF, Choudhury SR, Chun J, Naumenko V, Surewaard BG, Nelson MC, Ulke-Lemée A, Beck PL, Benediktsson H, Jevnikar AM, Snelgrove SL, Hickey MJ, Senger DL, James MT, Macdonald JA, Kubes P, Jenne CN, Muruve DA.

J Clin Invest. 2018 Jul 2;128(7):2894-2913. doi: 10.1172/JCI96640. Epub 2018 Jun 4.


Glucose Homeostasis Is Important for Immune Cell Viability during Candida Challenge and Host Survival of Systemic Fungal Infection.

Tucey TM, Verma J, Harrison PF, Snelgrove SL, Lo TL, Scherer AK, Barugahare AA, Powell DR, Wheeler RT, Hickey MJ, Beilharz TH, Naderer T, Traven A.

Cell Metab. 2018 May 1;27(5):988-1006.e7. doi: 10.1016/j.cmet.2018.03.019.


Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes.

Westhorpe CLV, Norman MU, Hall P, Snelgrove SL, Finsterbusch M, Li A, Lo C, Tan ZH, Li S, Nilsson SK, Kitching AR, Hickey MJ.

Nat Commun. 2018 Feb 21;9(1):747. doi: 10.1038/s41467-018-03181-4.


Activation of the sympathetic nervous system modulates neutrophil function.

Nicholls AJ, Wen SW, Hall P, Hickey MJ, Wong CHY.

J Leukoc Biol. 2018 Feb;103(2):295-309. doi: 10.1002/JLB.3MA0517-194RR. Epub 2017 Dec 21.


C5a receptor 1 promotes autoimmunity, neutrophil dysfunction and injury in experimental anti-myeloperoxidase glomerulonephritis.

Dick J, Gan PY, Ford SL, Odobasic D, Alikhan MA, Loosen SH, Hall P, Westhorpe CL, Li A, Ooi JD, Woodruff TM, Mackay CR, Kitching AR, Hickey MJ, Holdsworth SR.

Kidney Int. 2018 Mar;93(3):615-625. doi: 10.1016/j.kint.2017.09.018. Epub 2017 Dec 12.


CD39 and CD73 activity are protective in a mouse model of antiphospholipid antibody-induced miscarriages.

Samudra AN, Dwyer KM, Selan C, Freddi S, Murray-Segal L, Nikpour M, Hickey MJ, Peter K, Robson SC, Sashindranath M, Cowan PJ, Nandurkar HH.

J Autoimmun. 2018 Mar;88:131-138. doi: 10.1016/j.jaut.2017.10.009. Epub 2017 Nov 3.


Editorial: Inflammation in the CNS: Advancing the Field Using Intravital Imaging.

Pai S, Hickey MJ, Weninger W.

Front Immunol. 2017 Oct 2;8:1155. doi: 10.3389/fimmu.2017.01155. eCollection 2017. No abstract available.


Viewing immune regulation as it happens: in vivo imaging for investigation of regulatory T-cell function.

Hickey MJ, Chow Z.

Immunol Cell Biol. 2017 Jul;95(6):514-519. doi: 10.1038/icb.2017.33. Epub 2017 Apr 19. Review.


Development of a novel strategy to target CD39 antithrombotic activity to the endothelial-platelet microenvironment in kidney ischemia-reperfusion injury.

Sashindranath M, Dwyer KM, Dezfouli S, Selan C, Crikis S, Lu B, Yuan Y, Hickey MJ, Peter K, Robson SC, Cowan PJ, Nandurkar HH.

Purinergic Signal. 2017 Jun;13(2):259-265. doi: 10.1007/s11302-017-9558-3. Epub 2017 Mar 25.


A rapid monocyte response team.

Hickey MJ.

Blood. 2017 Mar 9;129(10):1237-1238. doi: 10.1182/blood-2017-01-759779. No abstract available.


Imaging Leukocyte Responses in the Kidney.

Finsterbusch M, Kitching AR, Hickey MJ.

Transplantation. 2017 Mar;101(3):506-516. doi: 10.1097/TP.0000000000001557. Review.


Isotope labelling by reduction of nitriles: Application to the synthesis of isotopologues of tolmetin and celecoxib.

Ellis-Sawyer K, Bragg RA, Bushby N, Elmore CS, Hickey MJ.

J Labelled Comp Radiopharm. 2017 Apr;60(4):213-220. doi: 10.1002/jlcr.3492. Epub 2017 Mar 5.


In Vivo Imaging of Inflamed Glomeruli Reveals Dynamics of Neutrophil Extracellular Trap Formation in Glomerular Capillaries.

Westhorpe CL, Bayard JE, O'Sullivan KM, Hall P, Cheng Q, Kitching AR, Hickey MJ.

Am J Pathol. 2017 Feb;187(2):318-331. doi: 10.1016/j.ajpath.2016.10.008. Epub 2016 Dec 18.


The synthesis of a tritium, carbon-14, and stable isotope-labeled cathepsin C inhibitors.

Allen P, Bragg RA, Caffrey M, Ericsson C, Hickey MJ, Kingston LP, Elmore CS.

J Labelled Comp Radiopharm. 2017 Feb;60(2):124-129. doi: 10.1002/jlcr.3483. Epub 2016 Dec 21.


Antibody Subclass Repertoire and Graft Outcome Following Solid Organ Transplantation.

Valenzuela NM, Hickey MJ, Reed EF.

Front Immunol. 2016 Oct 24;7:433. eCollection 2016. Review.


New priorities: Analysis of the New Kidney Allocation System on UCLA patients transplanted from the deceased donor waitlist.

Hickey MJ, Zheng Y, Valenzuela N, Zhang Q, Krystal C, Lum E, Tsai EW, Lipshutz GS, Gritsch HA, Danovitch G, Veale J, Gjertson D, Cecka M, Reed EF.

Hum Immunol. 2017 Jan;78(1):41-48. doi: 10.1016/j.humimm.2016.10.020. Epub 2016 Nov 3.


Acute antibody-mediated rejection in ABO-compatible pediatric liver transplant recipients: case series and review of the literature.

Wozniak LJ, Naini BV, Hickey MJ, Bhattacharyya S, Reed EF, Busuttil RW, Farmer DG, Vargas JH, Venick RS, McDiarmid SV.

Pediatr Transplant. 2017 Feb;21(1). doi: 10.1111/petr.12791. Epub 2016 Sep 5. Review.


Patrolling monocytes promote intravascular neutrophil activation and glomerular injury in the acutely inflamed glomerulus.

Finsterbusch M, Hall P, Li A, Devi S, Westhorpe CL, Kitching AR, Hickey MJ.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5172-81. doi: 10.1073/pnas.1606253113. Epub 2016 Aug 15.


Activated Renal Dendritic Cells Cross Present Intrarenal Antigens After Ischemia-Reperfusion Injury.

Snelgrove SL, Lo C, Hall P, Lo CY, Alikhan MA, Coates PT, Holdsworth SR, Hickey MJ, Kitching AR.

Transplantation. 2017 May;101(5):1013-1024. doi: 10.1097/TP.0000000000001427.


Syntheses of a radiolabelled CXCR2 antagonist AZD5069 and its major human metabolite.

Hickey MJ, Allen PH, Caffrey M, Hansen P, Kingston LP, Wilkinson DJ.

J Labelled Comp Radiopharm. 2016 Sep;59(11):432-8. doi: 10.1002/jlcr.3429. Epub 2016 Jul 27.


The synthesis of [(14) C]AZD5122. Incorporation of an IV (14) C-microtracer dose into a first in human study to determine the absolute oral bioavailability of AZD5122.

Hickey MJ, Allen PH, Kingston LP, Wilkinson DJ.

J Labelled Comp Radiopharm. 2016 May 30;59(6):245-9. doi: 10.1002/jlcr.3385.


Corrigendum: Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus.

Devi S, Li A, Westhorpe CL, Lo CY, Abeynaike LD, Snelgrove SL, Hall P, Ooi JD, Sobey CG, Kitching AR, Hickey MJ.

Nat Med. 2016 Apr;22(4):446. doi: 10.1038/nm0416-446a. No abstract available.


Abstracts of the 24th international isotope society (UK group) symposium: synthesis and applications of labelled compounds 2015.

Aigbirhio FI, Allwein S, Anwar A, Atzrodt J, Audisio D, Badman G, Bakale R, Berthon F, Bragg R, Brindle KM, Bushby N, Campos S, Cant AA, Chan MY, Colbon P, Cornelissen B, Czarny B, Derdau V, Dive V, Dunscombe M, Eggleston I, Ellis-Sawyer K, Elmore CS, Engstrom P, Ericsson C, Fairlamb IJ, Georgin D, Godfrey SP, He L, Hickey MJ, Huscroft IT, Kerr WJ, Lashford A, Lenz E, Lewinton S, L'Hermite MM, Lindelöf Å, Little G, Lockley WJ, Loreau O, Maddocks S, Marguerit M, Mirabello V, Mudd RJ, Nilsson GN, Owens PK, Pascu SI, Patriarche G, Pimlott SL, Pinault M, Plastow G, Racys DT, Reif J, Rossi J, Ruan J, Sarpaki S, Sephton SM, Simonsson R, Speed DJ, Sumal K, Sutherland A, Taran F, Thuleau A, Wang Y, Waring M, Watters WH, Wu J, Xiao J.

J Labelled Comp Radiopharm. 2016 Apr;59(4):175-86. doi: 10.1002/jlcr.3377. Epub 2016 Mar 18.


Alloantibody Generation and Effector Function Following Sensitization to Human Leukocyte Antigen.

Hickey MJ, Valenzuela NM, Reed EF.

Front Immunol. 2016 Feb 4;7:30. doi: 10.3389/fimmu.2016.00030. eCollection 2016. Review.


Dendritic Cell Migration and Antigen Presentation Are Coordinated by the Opposing Functions of the Tetraspanins CD82 and CD37.

Jones EL, Wee JL, Demaria MC, Blakeley J, Ho PK, Vega-Ramos J, Villadangos JA, van Spriel AB, Hickey MJ, Hämmerling GJ, Wright MD.

J Immunol. 2016 Feb 1;196(3):978-87. doi: 10.4049/jimmunol.1500357. Epub 2016 Jan 4.


Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.

de Waal L, Lewis TA, Rees MG, Tsherniak A, Wu X, Choi PS, Gechijian L, Hartigan C, Faloon PW, Hickey MJ, Tolliday N, Carr SA, Clemons PA, Munoz B, Wagner BK, Shamji AF, Koehler AN, Schenone M, Burgin AB, Schreiber SL, Greulich H, Meyerson M.

Nat Chem Biol. 2016 Feb;12(2):102-8. doi: 10.1038/nchembio.1984. Epub 2015 Dec 14.


Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors.

Schiffler MA, Antonysamy S, Bhattachar SN, Campanale KM, Chandrasekhar S, Condon B, Desai PV, Fisher MJ, Groshong C, Harvey A, Hickey MJ, Hughes NE, Jones SA, Kim EJ, Kuklish SL, Luz JG, Norman BH, Rathmell RE, Rizzo JR, Seng TW, Thibodeaux SJ, Woods TA, York JS, Yu XP.

J Med Chem. 2016 Jan 14;59(1):194-205. doi: 10.1021/acs.jmedchem.5b01249. Epub 2015 Dec 18.


Tetraspanin CD37 Regulates β2 Integrin-Mediated Adhesion and Migration in Neutrophils.

Wee JL, Schulze KE, Jones EL, Yeung L, Cheng Q, Pereira CF, Costin A, Ramm G, van Spriel AB, Hickey MJ, Wright MD.

J Immunol. 2015 Dec 15;195(12):5770-9. doi: 10.4049/jimmunol.1402414. Epub 2015 Nov 13.


CD99: An endothelial passport for leukocytes.

Hickey MJ.

J Exp Med. 2015 Jun 29;212(7):977. doi: 10.1084/jem.2127insight2. No abstract available.


Endogenous Toll-Like Receptor 9 Regulates AKI by Promoting Regulatory T Cell Recruitment.

Alikhan MA, Summers SA, Gan PY, Chan AJ, Khouri MB, Ooi JD, Ghali JR, Odobasic D, Hickey MJ, Kitching AR, Holdsworth SR.

J Am Soc Nephrol. 2016 Mar;27(3):706-14. doi: 10.1681/ASN.2014090927. Epub 2015 Jun 26.


Donor-specific HLA Antibodies Are Associated With Late Allograft Dysfunction After Pediatric Liver Transplantation.

Wozniak LJ, Hickey MJ, Venick RS, Vargas JH, Farmer DG, Busuttil RW, McDiarmid SV, Reed EF.

Transplantation. 2015 Jul;99(7):1416-22. doi: 10.1097/TP.0000000000000796.


Radial mobility and cytotoxic function of retroviral replicating vector transduced, non-adherent alloresponsive T lymphocytes.

Erickson KL, Hickey MJ, Kato Y, Malone CC, Owens GC, Prins RM, Liau LM, Kasahara N, Kruse CA.

J Vis Exp. 2015 Feb 11;(96). doi: 10.3791/52416.


CX3CR1 reduces kidney fibrosis by inhibiting local proliferation of profibrotic macrophages.

Engel DR, Krause TA, Snelgrove SL, Thiebes S, Hickey MJ, Boor P, Kitching AR, Kurts C.

J Immunol. 2015 Feb 15;194(4):1628-38. doi: 10.4049/jimmunol.1402149. Epub 2015 Jan 16.


Controlling the fire--tissue-specific mechanisms of effector regulatory T-cell homing.

Chow Z, Banerjee A, Hickey MJ.

Immunol Cell Biol. 2015 Apr;93(4):355-63. doi: 10.1038/icb.2014.117. Epub 2015 Jan 13. Review.


Mycobacterium tuberculosis strains lacking surface lipid phthiocerol dimycocerosate are susceptible to killing by an early innate host response.

Day TA, Mittler JE, Nixon MR, Thompson C, Miner MD, Hickey MJ, Liao RP, Pang JM, Shayakhmetov DM, Sherman DR.

Infect Immun. 2014 Dec;82(12):5214-22. doi: 10.1128/IAI.01340-13. Epub 2014 Oct 6.


Regulatory T cells dynamically regulate selectin ligand function during multiple challenge contact hypersensitivity.

Abeynaike LD, Deane JA, Westhorpe CL, Chow Z, Alikhan MA, Kitching AR, Issekutz A, Hickey MJ.

J Immunol. 2014 Nov 15;193(10):4934-44. doi: 10.4049/jimmunol.1400641. Epub 2014 Oct 1.


Stellate ganglion block used to treat symptoms associated with combat-related post-traumatic stress disorder: a case series of 166 patients.

Mulvaney SW, Lynch JH, Hickey MJ, Rahman-Rawlins T, Schroeder M, Kane S, Lipov E.

Mil Med. 2014 Oct;179(10):1133-40. doi: 10.7205/MILMED-D-14-00151.


Plant vigour at establishment and following defoliation are both associated with responses to drought in perennial ryegrass (Lolium perenne L.).

Hatier JH, Faville MJ, Hickey MJ, Koolaard JP, Schmidt J, Carey BL, Jones CS.

J Exp Bot. 2014 Nov;65(20):5823-34. doi: 10.1093/jxb/eru318. Epub 2014 Aug 6.


Small cell lung cancer cells express the late stage gBK tumor antigen: a possible immunotarget for the terminal disease.

Hoa NT, Ge L, Tajhya RB, Beeton C, Cornforth AN, Abolhoda A, Lambrecht N, DaCosta-Iyer M, Ouyang Y, Mai AP, Hong E, Shon J, Hickey MJ, Erickson KL, Kruse CA, Jadus MR.

Am J Transl Res. 2014 May 15;6(3):188-205. eCollection 2014.


Multiphoton fluorescence microscopy of the live kidney in health and disease.

Small DM, Sanchez WY, Roy S, Hickey MJ, Gobe GC.

J Biomed Opt. 2014 Feb;19(2):020901. doi: 10.1117/1.JBO.19.2.020901. Review.


A short expedient synthesis of [(14)C]Ticlopidine.

Hickey MJ, Kingston LP, Allen PH, Johnson T, Wilkinson DJ.

J Labelled Comp Radiopharm. 2014 Mar;57(3):172-4. doi: 10.1002/jlcr.3184. Epub 2014 Jan 27.


Perivascular macrophages mediate neutrophil recruitment during bacterial skin infection.

Abtin A, Jain R, Mitchell AJ, Roediger B, Brzoska AJ, Tikoo S, Cheng Q, Ng LG, Cavanagh LL, von Andrian UH, Hickey MJ, Firth N, Weninger W.

Nat Immunol. 2014 Jan;15(1):45-53. doi: 10.1038/ni.2769. Epub 2013 Nov 24.


Combining cellular and gene therapy approaches for treatment of intracranial tumors.

Hickey MJ, Kasahara N, Mueller BM, Kruse CA.

Oncoimmunology. 2013 Oct 1;2(10):e25989. Epub 2013 Sep 12.

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