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Items: 1 to 50 of 236

1.

Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis.

Montgomery SA, Young EF, Durham PG, Zulauf KE, Rank L, Miller BK, Hayden JD, Lin FC, Welch JT, Hickey AJ, Braunstein M.

PLoS One. 2018 Sep 27;13(9):e0204495. doi: 10.1371/journal.pone.0204495. eCollection 2018. Erratum in: PLoS One. 2018 Nov 5;13(11):e0207257.

2.

Hyperoxia increases maximum oxygen consumption and aerobic scope of intertidal fish facing acutely high temperatures.

McArley TJ, Hickey AJR, Herbert NA.

J Exp Biol. 2018 Nov 12;221(Pt 22). pii: jeb189993. doi: 10.1242/jeb.189993.

PMID:
30254026
3.

Altered Metabolic Profile of Triglyceride-Rich Lipoproteins in Gut-Lymph of Rodent Models of Sepsis and Gut Ischemia-Reperfusion Injury.

Hong J, Nachkebia S, Tun SM, Petzer A, Windsor JA, Hickey AJ, Phillips AR.

Dig Dis Sci. 2018 Sep 4. doi: 10.1007/s10620-018-5270-6. [Epub ahead of print]

PMID:
30182310
4.

Spatiotemporal and demographic variation in the diet of New Zealand lesser short-tailed bats (Mystacina tuberculata).

Czenze ZJ, Tucker JL, Clare EL, Littlefair JE, Hemprich-Bennett D, Oliveira HFM, Brigham RM, Hickey AJR, Parsons S.

Ecol Evol. 2018 Jul 9;8(15):7599-7610. doi: 10.1002/ece3.4268. eCollection 2018 Aug.

5.

Pharmacokinetics and pharmacodynamics of high doses of inhaled dry powder drugs.

Kukut Hatipoglu M, Hickey AJ, Garcia-Contreras L.

Int J Pharm. 2018 Oct 5;549(1-2):306-316. doi: 10.1016/j.ijpharm.2018.07.050. Epub 2018 Aug 2.

PMID:
30077761
6.

Exercise recovery increases skeletal muscle H2O2 emission and mitochondrial respiratory capacity following two-weeks of limb immobilization.

Pileggi CA, Hedges CP, D'Souza RF, Durainayagam BR, Markworth JF, Hickey AJR, Mitchell CJ, Cameron-Smith D.

Free Radic Biol Med. 2018 Aug 20;124:241-248. doi: 10.1016/j.freeradbiomed.2018.06.012. Epub 2018 Jun 15.

PMID:
29909291
7.

Effects of Formulation Variables on Lung Dosimetry of Albuterol Sulfate Suspension and Beclomethasone Dipropionate Solution Metered Dose Inhalers.

Schroeter JD, Sheth P, Hickey AJ, Asgharian B, Price OT, Holt JT, Conti DS, Saluja B.

AAPS PharmSciTech. 2018 Jul;19(5):2335-2345. doi: 10.1208/s12249-018-1071-7. Epub 2018 Jun 1.

PMID:
29858973
8.

Calcium mishandling impairs contraction in right ventricular hypertrophy prior to overt heart failure.

Power AS, Hickey AJ, Crossman DJ, Loiselle DS, Ward ML.

Pflugers Arch. 2018 Jul;470(7):1115-1126. doi: 10.1007/s00424-018-2125-0. Epub 2018 Mar 10.

PMID:
29525825
9.

Co-suspension delivery technology in pressurized metered-dose inhalers for multi-drug dosing in the treatment of respiratory diseases.

Ferguson GT, Hickey AJ, Dwivedi S.

Respir Med. 2018 Jan;134:16-23. doi: 10.1016/j.rmed.2017.09.012. Epub 2017 Sep 25. Review.

PMID:
29413503
10.

Oxygen- and capacity-limited thermal tolerance: blurring ecology and physiology.

Jutfelt F, Norin T, Ern R, Overgaard J, Wang T, McKenzie DJ, Lefevre S, Nilsson GE, Metcalfe NB, Hickey AJR, Brijs J, Speers-Roesch B, Roche DG, Gamperl AK, Raby GD, Morgan R, Esbaugh AJ, Gräns A, Axelsson M, Ekström A, Sandblom E, Binning SA, Hicks JW, Seebacher F, Jørgensen C, Killen SS, Schulte PM, Clark TD.

J Exp Biol. 2018 Jan 10;221(Pt 1). pii: jeb169615. doi: 10.1242/jeb.169615. No abstract available.

11.

Reproducibility, sharing and progress in nanomaterial databases.

Tropsha A, Mills KC, Hickey AJ.

Nat Nanotechnol. 2017 Dec 6;12(12):1111-1114. doi: 10.1038/nnano.2017.233. No abstract available.

PMID:
29209007
12.

Density and Shape Factor Terms in Stokes' Equation for Aerodynamic Behavior of Aerosols.

Hickey AJ, Edwards DA.

J Pharm Sci. 2018 Mar;107(3):794-796. doi: 10.1016/j.xphs.2017.11.005. Epub 2017 Nov 14.

PMID:
29154770
13.

Mitochondrial glycerol 3-phosphate facilitates bumblebee pre-flight thermogenesis.

Masson SWC, Hedges CP, Devaux JBL, James CS, Hickey AJR.

Sci Rep. 2017 Oct 12;7(1):13107. doi: 10.1038/s41598-017-13454-5.

14.

Changes in mitochondrial respiration in the human placenta over gestation.

Holland OJ, Hickey AJR, Alvsaker A, Moran S, Hedges C, Chamley LW, Perkins AV.

Placenta. 2017 Sep;57:102-112. doi: 10.1016/j.placenta.2017.06.011. Epub 2017 Jun 15.

PMID:
28863998
15.

Reductive Metabolism Influences the Toxicity and Pharmacokinetics of the Hypoxia-Targeted Benzotriazine Di-Oxide Anticancer Agent SN30000 in Mice.

Gu Y, Chang TT, Wang J, Jaiswal JK, Edwards D, Downes NJ, Liyanage HDS, Lynch CRH, Pruijn FB, Hickey AJR, Hay MP, Wilson WR, Hicks KO.

Front Pharmacol. 2017 Aug 11;8:531. doi: 10.3389/fphar.2017.00531. eCollection 2017.

16.

Chronic warm exposure impairs growth performance and reduces thermal safety margins in the common triplefin fish (Forsterygion lapillum).

McArley TJ, Hickey AJR, Herbert NA.

J Exp Biol. 2017 Oct 1;220(Pt 19):3527-3535. doi: 10.1242/jeb.162099. Epub 2017 Jul 31.

17.

Influence of Formulation Factors on the Aerosol Performance of Suspension and Solution Metered Dose Inhalers: A Systematic Approach.

Sheth P, Sandell D, Conti DS, Holt JT, Hickey AJ, Saluja B.

AAPS J. 2017 Sep;19(5):1396-1410. doi: 10.1208/s12248-017-0095-3. Epub 2017 Jun 7.

PMID:
28593514
18.

Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals.

Durham PG, Hanif SN, Contreras LG, Young EF, Braunstein MS, Hickey AJ.

J Vis Exp. 2017 Mar 30;(121). doi: 10.3791/55356.

19.

Hepatic tuberculosis in human immunodeficiency virus co-infected adults: a case series of South African adults.

Gounder L, Moodley P, Drain PK, Hickey AJ, Moosa MS.

BMC Infect Dis. 2017 Feb 1;17(1):115. doi: 10.1186/s12879-017-2222-2.

20.

Maternal High Fat Diet Alters Skeletal Muscle Mitochondrial Catalytic Activity in Adult Male Rat Offspring.

Pileggi CA, Hedges CP, Segovia SA, Markworth JF, Durainayagam BR, Gray C, Zhang XD, Barnett MP, Vickers MH, Hickey AJ, Reynolds CM, Cameron-Smith D.

Front Physiol. 2016 Nov 18;7:546. eCollection 2016.

21.

Changes in mitochondrial morphology and organization can enhance energy supply from mitochondrial oxidative phosphorylation in diabetic cardiomyopathy.

Jarosz J, Ghosh S, Delbridge LM, Petzer A, Hickey AJ, Crampin EJ, Hanssen E, Rajagopal V.

Am J Physiol Cell Physiol. 2017 Feb 1;312(2):C190-C197. doi: 10.1152/ajpcell.00298.2016. Epub 2016 Nov 30.

22.

Systems biology for organotypic cell cultures.

Grego S, Dougherty ER, Alexander FJ, Auerbach SS, Berridge BR, Bittner ML, Casey W, Cooley PC, Dash A, Ferguson SS, Fennell TR, Hawkins BT, Hickey AJ, Kleensang A, Liebman MNJ, Martin F, Maull EA, Paragas J, Qiao GG, Ramaiahgari S, Sumner SJ, Yoon M.

ALTEX. 2017;34(2):301-310. doi: 10.14573/altex.1608221. Epub 2016 Nov 14.

23.

Nanomaterial Drug Products: Manufacturing and Analytical Perspectives.

Sayes CM, Aquino GV, Hickey AJ.

AAPS J. 2017 Jan;19(1):18-25. doi: 10.1208/s12248-016-0008-x. Epub 2016 Nov 7. Review.

PMID:
27822601
24.

Thermodynamic analysis questions claims of improved cardiac efficiency by dietary fish oil.

Loiselle DS, Han JC, Goo E, Chapman B, Barclay CJ, Hickey AJ, Taberner AJ.

J Gen Physiol. 2016 Sep;148(3):183-93. doi: 10.1085/jgp.201611620.

25.

Cold and alone? Roost choice and season affect torpor patterns in lesser short-tailed bats.

Czenze ZJ, Brigham RM, Hickey AJ, Parsons S.

Oecologia. 2017 Jan;183(1):1-8. doi: 10.1007/s00442-016-3707-1. Epub 2016 Aug 25.

PMID:
27561779
26.

Mitochondrial dysfunction in peripheral blood mononuclear cells in early experimental and clinical acute pancreatitis.

Chakraborty M, Hickey AJ, Petrov MS, Macdonald JR, Thompson N, Newby L, Sim D, Windsor JA, Phillips AR.

Pancreatology. 2016 Sep-Oct;16(5):739-47. doi: 10.1016/j.pan.2016.06.659. Epub 2016 Jun 27.

PMID:
27473495
27.

Inhaled Pyrazinoic Acid Esters for the Treatment of Tuberculosis.

Young EF, Perkowski E, Malik S, Hayden JD, Durham PG, Zhong L, Welch JT, Braunstein MS, Hickey AJ.

Pharm Res. 2016 Oct;33(10):2495-505. doi: 10.1007/s11095-016-1974-5. Epub 2016 Jun 28.

PMID:
27351427
28.

Steatotic livers are susceptible to normothermic ischemia-reperfusion injury from mitochondrial Complex-I dysfunction.

Chu MJ, Premkumar R, Hickey AJ, Jiang Y, Delahunt B, Phillips AR, Bartlett AS.

World J Gastroenterol. 2016 May 21;22(19):4673-84. doi: 10.3748/wjg.v22.i19.4673.

29.

A dry powder combination of pyrazinoic acid and its n-propyl ester for aerosol administration to animals.

Durham PG, Young EF, Braunstein MS, Welch JT, Hickey AJ.

Int J Pharm. 2016 Dec 5;514(2):384-391. doi: 10.1016/j.ijpharm.2016.04.063. Epub 2016 Apr 26.

PMID:
27130363
30.

Impaired ADP channeling to mitochondria and elevated reactive oxygen species in hypertensive hearts.

Power AS, Pham T, Loiselle DS, Crossman DH, Ward ML, Hickey AJ.

Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1649-57. doi: 10.1152/ajpheart.00050.2016. Epub 2016 Apr 15.

31.

Real-Time Investigation of Tuberculosis Transmission: Developing the Respiratory Aerosol Sampling Chamber (RASC).

Wood R, Morrow C, Barry CE 3rd, Bryden WA, Call CJ, Hickey AJ, Rodes CE, Scriba TJ, Blackburn J, Issarow C, Mulder N, Woodward J, Moosa A, Singh V, Mizrahi V, Warner DF.

PLoS One. 2016 Jan 25;11(1):e0146658. doi: 10.1371/journal.pone.0146658. eCollection 2016.

32.

Impact of Patient Preparation on the Diagnostic Performance of 18F-FDG PET in Cardiac Sarcoidosis: A Systematic Review and Meta-analysis.

Tang R, Wang JT, Wang L, Le K, Huang Y, Hickey AJ, Emmett L.

Clin Nucl Med. 2016 Jul;41(7):e327-39. doi: 10.1097/RLU.0000000000001063. Review.

PMID:
26646995
33.

Inhaled drug treatment for tuberculosis: Past progress and future prospects.

Hickey AJ, Durham PG, Dharmadhikari A, Nardell EA.

J Control Release. 2016 Oct 28;240:127-134. doi: 10.1016/j.jconrel.2015.11.018. Epub 2015 Nov 18. Review.

PMID:
26596254
34.

Correction for Spray Dried Aerosol Particles of Pyrazinoic Acid Salts for Tuberculosis Therapy.

Durham PG, Zhang Y, German N, Mortensen N, Dhillon J, Mitchison DA, Fourie PB, Hickey AJ.

Mol Pharm. 2015 Oct 5;12(10):3782. doi: 10.1021/acs.molpharmaceut.5b00673. Epub 2015 Sep 22. No abstract available.

PMID:
26394135
35.

Spray Dried Aerosol Particles of Pyrazinoic Acid Salts for Tuberculosis Therapy. [Corrected].

Durham PG, Zhang Y, German N, Mortensen N, Dhillon J, Mitchison DA, Fourie PB, Hickey AJ.

Mol Pharm. 2015 Aug 3;12(8):2574-81. doi: 10.1021/acs.molpharmaceut.5b00118. Epub 2015 Jul 1. Erratum in: Mol Pharm. 2015 Oct 5;12(10):3782.

PMID:
26098136
36.

A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection.

Hickey AJ, Gounder L, Moosa MY, Drain PK.

BMC Infect Dis. 2015 May 6;15:209. doi: 10.1186/s12879-015-0944-6. Review.

37.

Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training.

Vincent G, Lamon S, Gant N, Vincent PJ, MacDonald JR, Markworth JF, Edge JA, Hickey AJ.

Front Physiol. 2015 Feb 24;6:51. doi: 10.3389/fphys.2015.00051. eCollection 2015.

38.

Impact of ischemic preconditioning on outcome in clinical liver surgery: a systematic review.

Chu MJ, Vather R, Hickey AJ, Phillips AR, Bartlett AS.

Biomed Res Int. 2015;2015:370451. doi: 10.1155/2015/370451. Epub 2015 Feb 10. Review.

39.

Temperature acclimation of mitochondria function from the hearts of a temperate wrasse (Notolabrus celidotus).

Iftikar FI, Morash AJ, Cook DG, Herbert NA, Hickey AJ.

Comp Biochem Physiol A Mol Integr Physiol. 2015 Jun;184:46-55. doi: 10.1016/j.cbpa.2015.01.017. Epub 2015 Jan 31.

PMID:
25645295
40.

In vitro dry powder inhaler formulation performance considerations.

Ziffels S, Bemelmans NL, Durham PG, Hickey AJ.

J Control Release. 2015 Feb 10;199:45-52. doi: 10.1016/j.jconrel.2014.11.035. Epub 2014 Dec 9.

PMID:
25497311
41.

Mitochondrial dysfunction in steatotic rat livers occurs because a defect in complex i makes the liver susceptible to prolonged cold ischemia.

Chu MJ, Hickey AJ, Jiang Y, Petzer A, Bartlett AS, Phillips AR.

Liver Transpl. 2015 Mar;21(3):396-407. doi: 10.1002/lt.24024. Epub 2015 Jan 22.

42.

Targeting inhaled therapy beyond the lungs.

Mortensen NP, Hickey AJ.

Respiration. 2014;88(5):353-4. Review.

43.

Thermal plasticity of skeletal muscle mitochondrial activity and whole animal respiration in a common intertidal triplefin fish, Forsterygion lapillum (Family: Tripterygiidae).

Khan JR, Iftikar FI, Herbert NA, Gnaiger E, Hickey AJ.

J Comp Physiol B. 2014 Dec;184(8):991-1001. doi: 10.1007/s00360-014-0861-9. Epub 2014 Oct 1.

PMID:
25269418
44.

Could thermal sensitivity of mitochondria determine species distribution in a changing climate?

Iftikar FI, MacDonald JR, Baker DW, Renshaw GM, Hickey AJ.

J Exp Biol. 2014 Jul 1;217(Pt 13):2348-57. doi: 10.1242/jeb.098798.

45.

The role of particle physico-chemical properties in pulmonary drug delivery for tuberculosis therapy.

Mortensen NP, Durham P, Hickey AJ.

J Microencapsul. 2014;31(8):785-95. doi: 10.3109/02652048.2014.932029. Epub 2014 Aug 4. Review.

PMID:
25090595
46.

Ob/ob mouse livers show decreased oxidative phosphorylation efficiencies and anaerobic capacities after cold ischemia.

Chu MJ, Hickey AJ, Tagaloa S, Zhang L, Dare AJ, MacDonald JR, Yeong ML, Bartlett AS, Phillips AR.

PLoS One. 2014 Jun 23;9(6):e100609. doi: 10.1371/journal.pone.0100609. eCollection 2014.

47.

Aerodynamic and electrostatic properties of model dry powder aerosols: a comprehensive study of formulation factors.

Telko MJ, Hickey AJ.

AAPS PharmSciTech. 2014 Dec;15(6):1378-97. doi: 10.1208/s12249-014-0144-5. Epub 2014 Jun 18.

48.

Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart.

Pham T, Loiselle D, Power A, Hickey AJ.

Am J Physiol Cell Physiol. 2014 Sep 15;307(6):C499-507. doi: 10.1152/ajpcell.00006.2014. Epub 2014 Jun 11.

49.

Scale of health: indices of safety and efficacy in the evolving environment of large biological datasets.

Sayes CM, Staats H, Hickey AJ.

Pharm Res. 2014 Sep;31(9):2256-65. doi: 10.1007/s11095-014-1415-2. Epub 2014 Jun 12. Review.

PMID:
24919930
50.

Controlled delivery of inhaled therapeutic agents.

Hickey AJ.

J Control Release. 2014 Sep 28;190:182-8. doi: 10.1016/j.jconrel.2014.05.058. Epub 2014 Jun 5. Review.

PMID:
24907604

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