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Items: 1 to 50 of 90

1.

The Influence of Innate Lymphoid Cells and Unconventional T Cells in Chronic Inflammatory Lung Disease.

Borger JG, Lau M, Hibbs ML.

Front Immunol. 2019 Jul 11;10:1597. doi: 10.3389/fimmu.2019.01597. eCollection 2019. Review.

2.

IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization.

Eissmann MF, Dijkstra C, Jarnicki A, Phesse T, Brunnberg J, Poh AR, Etemadi N, Tsantikos E, Thiem S, Huntington ND, Hibbs ML, Boussioutas A, Grimbaldeston MA, Buchert M, O'Donoghue RJJ, Masson F, Ernst M.

Nat Commun. 2019 Jun 21;10(1):2735. doi: 10.1038/s41467-019-10676-1.

3.

Infections after a traumatic brain injury: The complex interplay between the immune and neurological systems.

Sharma R, Shultz SR, Robinson MJ, Belli A, Hibbs ML, O'Brien TJ, Semple BD.

Brain Behav Immun. 2019 Jul;79:63-74. doi: 10.1016/j.bbi.2019.04.034. Epub 2019 Apr 25. Review.

PMID:
31029794
4.

Regulation of hematopoietic cell signaling by SHIP-1 inositol phosphatase: growth factors and beyond.

Hibbs ML, Raftery AL, Tsantikos E.

Growth Factors. 2018 Dec;36(5-6):213-231. doi: 10.1080/08977194.2019.1569649. Epub 2019 Feb 15. Review.

PMID:
30764683
5.

Urinary B-cell-activating factor of the tumour necrosis factor family (BAFF) in systemic lupus erythematosus.

Vincent FB, Kandane-Rathnayake R, Hoi AY, Slavin L, Godsell JD, Kitching AR, Harris J, Nelson CL, Jenkins AJ, Chrysostomou A, Hibbs ML, Kerr PG, Rischmueller M, Mackay F, Morand EF.

Lupus. 2018 Nov;27(13):2029-2040. doi: 10.1177/0961203318804885. Epub 2018 Oct 9.

PMID:
30301439
6.

LMP2 immunoproteasome promotes lymphocyte survival by degrading apoptotic BH3-only proteins.

Zanker D, Pang K, Oveissi S, Lu C, Faou P, Nowell C, Mbogo GW, Carotta S, Quillici C, Karupiah G, Hibbs ML, Nutt SL, Neeson P, Puthalakath H, Chen W.

Immunol Cell Biol. 2018 Oct;96(9):981-993. doi: 10.1111/imcb.12163. Epub 2018 Jun 3.

PMID:
29738610
7.

Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease.

Tsantikos E, Lau M, Castelino CM, Maxwell MJ, Passey SL, Hansen MJ, McGregor NE, Sims NA, Steinfort DP, Irving LB, Anderson GP, Hibbs ML.

J Clin Invest. 2018 Jun 1;128(6):2406-2418. doi: 10.1172/JCI98224. Epub 2018 Apr 30.

8.

Foxp3+ Tregs are recruited to the retina to repair pathological angiogenesis.

Deliyanti D, Talia DM, Zhu T, Maxwell MJ, Agrotis A, Jerome JR, Hargreaves EM, Gerondakis S, Hibbs ML, Mackay F, Wilkinson-Berka JL.

Nat Commun. 2017 Sep 29;8(1):748. doi: 10.1038/s41467-017-00751-w.

9.

SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages.

Luo L, Bokil NJ, Wall AA, Kapetanovic R, Lansdaal NM, Marceline F, Burgess BJ, Tong SJ, Guo Z, Alexandrov K, Ross IL, Hibbs ML, Stow JL, Sweet MJ.

Nat Commun. 2017 Jan 18;8:14133. doi: 10.1038/ncomms14133.

10.

Csk-binding protein controls red blood cell development via regulation of Lyn tyrosine kinase activity.

Plani-Lam JH, Slavova-Azmanova NS, Kucera N, Louw A, Satiaputra J, Singer P, Lam KP, Hibbs ML, Ingley E.

Exp Hematol. 2017 Feb;46:70-82.e10. doi: 10.1016/j.exphem.2016.10.001. Epub 2016 Oct 15.

11.

The contributions of lung macrophage and monocyte heterogeneity to influenza pathogenesis.

Duan M, Hibbs ML, Chen W.

Immunol Cell Biol. 2017 Mar;95(3):225-235. doi: 10.1038/icb.2016.97. Epub 2016 Sep 27. Review.

PMID:
27670791
12.

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.

de Valle E, Grigoriadis G, O'Reilly LA, Willis SN, Maxwell MJ, Corcoran LM, Tsantikos E, Cornish JK, Fairfax KA, Vasanthakumar A, Febbraio MA, Hibbs ML, Pellegrini M, Banerjee A, Hodgkin PD, Kallies A, Mackay F, Strasser A, Gerondakis S, Gugasyan R.

J Exp Med. 2016 Apr 4;213(4):621-41. doi: 10.1084/jem.20151182. Epub 2016 Mar 28.

13.

VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury.

Sato T, Paquet-Fifield S, Harris NC, Roufail S, Turner DJ, Yuan Y, Zhang YF, Fox SB, Hibbs ML, Wilkinson-Berka JL, Williams RA, Stacker SA, Sly PD, Achen MG.

J Pathol. 2016 Jun;239(2):152-61. doi: 10.1002/path.4708. Epub 2016 Mar 30.

14.

Pathogenic Inflammation and Its Therapeutic Targeting in Systemic Lupus Erythematosus.

Gottschalk TA, Tsantikos E, Hibbs ML.

Front Immunol. 2015 Oct 28;6:550. doi: 10.3389/fimmu.2015.00550. eCollection 2015. Review.

15.

CD11b immunophenotyping identifies inflammatory profiles in the mouse and human lungs.

Duan M, Steinfort DP, Smallwood D, Hew M, Chen W, Ernst M, Irving LB, Anderson GP, Hibbs ML.

Mucosal Immunol. 2016 Mar;9(2):550-63. doi: 10.1038/mi.2015.84. Epub 2015 Sep 30.

PMID:
26422753
16.

BAFF-driven autoimmunity requires CD19 expression.

Fairfax KA, Tsantikos E, Figgett WA, Vincent FB, Quah PS, LePage M, Hibbs ML, Mackay F.

J Autoimmun. 2015 Aug;62:1-10. doi: 10.1016/j.jaut.2015.06.001. Epub 2015 Jun 20.

PMID:
26103922
17.

Manipulation of B-cell responses with histone deacetylase inhibitors.

Waibel M, Christiansen AJ, Hibbs ML, Shortt J, Jones SA, Simpson I, Light A, O'Donnell K, Morand EF, Tarlinton DM, Johnstone RW, Hawkins ED.

Nat Commun. 2015 Apr 27;6:6838. doi: 10.1038/ncomms7838.

PMID:
25913720
18.

The tyrosine kinase Lyn limits the cytokine responsiveness of plasma cells to restrict their accumulation in mice.

Infantino S, Jones SA, Walker JA, Maxwell MJ, Light A, O'Donnell K, Tsantikos E, Peperzak V, Phesse T, Ernst M, Mackay F, Hibbs ML, Fairfax KA, Tarlinton DM.

Sci Signal. 2014 Aug 12;7(338):ra77. doi: 10.1126/scisignal.2005105.

PMID:
25118329
19.

SHIP-1 deficiency in the myeloid compartment is insufficient to induce myeloid expansion or chronic inflammation.

Maxwell MJ, Srivastava N, Park MY, Tsantikos E, Engelman RW, Kerr WG, Hibbs ML.

Genes Immun. 2014 Apr;15(4):233-40. doi: 10.1038/gene.2014.9. Epub 2014 Mar 6.

PMID:
24598798
20.

Lyn kinase plays important roles in erythroid expansion, maturation and erythropoietin receptor signalling by regulating inhibitory signalling pathways that control survival.

Slavova-Azmanova NS, Kucera N, Louw A, Satiaputra J, Handoko A, Singer P, Stone L, McCarthy DJ, Klinken SP, Hibbs ML, Ingley E.

Biochem J. 2014 May 1;459(3):455-66. doi: 10.1042/BJ20130903.

21.

The CD19 signalling molecule is elevated in NOD mice and controls type 1 diabetes development.

Ziegler AI, Le Page MA, Maxwell MJ, Stolp J, Guo H, Jayasimhan A, Hibbs ML, Santamaria P, Miller JF, Plebanski M, Silveira PA, Slattery RM.

Diabetologia. 2013 Dec;56(12):2659-68. doi: 10.1007/s00125-013-3038-2. Epub 2013 Sep 8.

PMID:
24013782
22.

Interleukin-6 trans-signaling exacerbates inflammation and renal pathology in lupus-prone mice.

Tsantikos E, Maxwell MJ, Putoczki T, Ernst M, Rose-John S, Tarlinton DM, Hibbs ML.

Arthritis Rheum. 2013 Oct;65(10):2691-702. doi: 10.1002/art.38061.

23.

Gain-of-function Lyn induces anemia: appropriate Lyn activity is essential for normal erythropoiesis and Epo receptor signaling.

Slavova-Azmanova NS, Kucera N, Satiaputra J, Stone L, Magno A, Maxwell MJ, Quilici C, Erber W, Klinken SP, Hibbs ML, Ingley E.

Blood. 2013 Jul 11;122(2):262-71. doi: 10.1182/blood-2012-10-463158. Epub 2013 May 21.

24.

Loss of STAT6 promotes autoimmune disease and atopy on a susceptible genetic background.

Lau M, Tsantikos E, Maxwell MJ, Tarlinton DM, Anderson GP, Hibbs ML.

J Autoimmun. 2012 Dec;39(4):388-97. doi: 10.1016/j.jaut.2012.06.003. Epub 2012 Aug 4.

PMID:
22867713
25.

Genetic interdependence of Lyn and negative regulators of B cell receptor signaling in autoimmune disease development.

Tsantikos E, Maxwell MJ, Kountouri N, Harder KW, Tarlinton DM, Hibbs ML.

J Immunol. 2012 Aug 15;189(4):1726-36. doi: 10.4049/jimmunol.1103427. Epub 2012 Jul 13.

26.

Phosphatidylinositol-3 kinase activity in B cells is negatively regulated by Lyn tyrosine kinase.

Xu Y, Huntington ND, Harder KW, Nandurkar H, Hibbs ML, Tarlinton DM.

Immunol Cell Biol. 2012 Oct;90(9):903-11. doi: 10.1038/icb.2012.31. Epub 2012 Jul 10.

PMID:
22777522
27.

Distinct macrophage subpopulations characterize acute infection and chronic inflammatory lung disease.

Duan M, Li WC, Vlahos R, Maxwell MJ, Anderson GP, Hibbs ML.

J Immunol. 2012 Jul 15;189(2):946-55. doi: 10.4049/jimmunol.1200660. Epub 2012 Jun 11.

28.

Attenuation of phosphoinositide 3-kinase δ signaling restrains autoimmune disease.

Maxwell MJ, Tsantikos E, Kong AM, Vanhaesebroeck B, Tarlinton DM, Hibbs ML.

J Autoimmun. 2012 Jun;38(4):381-91. doi: 10.1016/j.jaut.2012.04.001. Epub 2012 Apr 25.

PMID:
22537464
29.

Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells.

Krebs DL, Chehal MK, Sio A, Huntington ND, Da ML, Ziltener P, Inglese M, Kountouri N, Priatel JJ, Jones J, Tarlinton DM, Anderson GP, Hibbs ML, Harder KW.

J Immunol. 2012 May 15;188(10):5094-105. doi: 10.4049/jimmunol.1103395. Epub 2012 Apr 9.

30.

New reagents for improved in vitro and in vivo examination of TGF-β signalling.

Luwor RB, Wang B, Nheu TV, Iaria J, Tsantikos E, Hibbs ML, Sieber OM, Zhu HJ.

Growth Factors. 2011 Oct;29(5):211-8. doi: 10.3109/08977194.2011.615311.

PMID:
21913800
31.

Sarcoidal reactions in regional lymph nodes of patients with early stage non-small cell lung cancer predict improved disease-free survival: a pilot case-control study.

Steinfort DP, Tsui A, Grieve J, Hibbs ML, Anderson GP, Irving LB.

Hum Pathol. 2012 Mar;43(3):333-8. doi: 10.1016/j.humpath.2011.05.006. Epub 2011 Aug 10.

PMID:
21835432
32.

Genetic segregation of inflammatory lung disease and autoimmune disease severity in SHIP-1-/- mice.

Maxwell MJ, Duan M, Armes JE, Anderson GP, Tarlinton DM, Hibbs ML.

J Immunol. 2011 Jun 15;186(12):7164-75. doi: 10.4049/jimmunol.1004185. Epub 2011 May 13.

33.

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation.

Nguyen NY, Maxwell MJ, Ooms LM, Davies EM, Hilton AA, Collinge JE, Hilton DJ, Kile BT, Mitchell CA, Hibbs ML, Jane SM, Curtis DJ.

Blood. 2011 May 19;117(20):5362-71. doi: 10.1182/blood-2011-01-331041. Epub 2011 Mar 18.

PMID:
21421839
34.

B-cell stage and context-dependent requirements for survival signals from BAFF and the B-cell receptor.

Mackay F, Figgett WA, Saulep D, Lepage M, Hibbs ML.

Immunol Rev. 2010 Sep;237(1):205-25. doi: 10.1111/j.1600-065X.2010.00944.x. Review.

PMID:
20727038
35.

Plasma cell development and survival.

Oracki SA, Walker JA, Hibbs ML, Corcoran LM, Tarlinton DM.

Immunol Rev. 2010 Sep;237(1):140-59. doi: 10.1111/j.1600-065X.2010.00940.x. Review.

PMID:
20727034
36.

Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit.

Perugini M, Brown AL, Salerno DG, Booker GW, Stojkoski C, Hercus TR, Lopez AF, Hibbs ML, Gonda TJ, D'Andrea RJ.

Blood. 2010 Apr 22;115(16):3346-53. doi: 10.1182/blood-2009-08-235846. Epub 2010 Feb 19.

37.

Autoimmune disease in Lyn-deficient mice is dependent on an inflammatory environment established by IL-6.

Tsantikos E, Oracki SA, Quilici C, Anderson GP, Tarlinton DM, Hibbs ML.

J Immunol. 2010 Feb 1;184(3):1348-60. doi: 10.4049/jimmunol.0901878. Epub 2009 Dec 30.

38.

CTLA4Ig alters the course of autoimmune disease development in Lyn-/- mice.

Oracki SA, Tsantikos E, Quilici C, Light A, Schmidt T, Lew AM, Martin JE, Smith KG, Hibbs ML, Tarlinton DM.

J Immunol. 2010 Jan 15;184(2):757-63. doi: 10.4049/jimmunol.0804349. Epub 2009 Dec 4.

39.

Perturbation of the CD4 T cell compartment and expansion of regulatory T cells in autoimmune-prone Lyn-deficient mice.

Tsantikos E, Quilici C, Harder KW, Wang B, Zhu HJ, Anderson GP, Tarlinton DM, Hibbs ML.

J Immunol. 2009 Aug 15;183(4):2484-94. doi: 10.4049/jimmunol.0804346. Epub 2009 Jul 20.

40.

A kinase-dead allele of Lyn attenuates autoimmune disease normally associated with Lyn deficiency.

Verhagen AM, Wallace ME, Goradia A, Jones SA, Croom HA, Metcalf D, Collinge JE, Maxwell MJ, Hibbs ML, Alexander WS, Hilton DJ, Kile BT, Starr R.

J Immunol. 2009 Feb 15;182(4):2020-9. doi: 10.4049/jimmunol.0803127.

41.

A system for quantifying the patterning of the lymphatic vasculature.

Shayan R, Karnezis T, Tsantikos E, Williams SP, Runting AS, Ashton MW, Achen MG, Hibbs ML, Stacker SA.

Growth Factors. 2007 Dec;25(6):417-25. doi: 10.1080/08977190801932550.

PMID:
18365872
42.

Epidermal growth factor receptor signaling to Erk1/2 and STATs control the intensity of the epithelial inflammatory responses to rhinovirus infection.

Liu K, Gualano RC, Hibbs ML, Anderson GP, Bozinovski S.

J Biol Chem. 2008 Apr 11;283(15):9977-85. doi: 10.1074/jbc.M710257200. Epub 2008 Feb 13.

43.
44.

Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2.

McColl BK, Paavonen K, Karnezis T, Harris NC, Davydova N, Rothacker J, Nice EC, Harder KW, Roufail S, Hibbs ML, Rogers PA, Alitalo K, Stacker SA, Achen MG.

FASEB J. 2007 Apr;21(4):1088-98. Epub 2007 Jan 22.

PMID:
17242158
45.

Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimulated cells.

Ingley E, Schneider JR, Payne CJ, McCarthy DJ, Harder KW, Hibbs ML, Klinken SP.

J Biol Chem. 2006 Oct 20;281(42):31920-9. Epub 2006 Aug 18.

46.

The duplicitous nature of the Lyn tyrosine kinase in growth factor signaling.

Hibbs ML, Harder KW.

Growth Factors. 2006 Jun;24(2):137-49.

PMID:
16801133
47.

Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity.

Beavitt SJ, Harder KW, Kemp JM, Jones J, Quilici C, Casagranda F, Lam E, Turner D, Brennan S, Sly PD, Tarlinton DM, Anderson GP, Hibbs ML.

J Immunol. 2005 Aug 1;175(3):1867-75.

48.

Vascular endothelial growth factor D is dispensable for development of the lymphatic system.

Baldwin ME, Halford MM, Roufail S, Williams RA, Hibbs ML, Grail D, Kubo H, Stacker SA, Achen MG.

Mol Cell Biol. 2005 Mar;25(6):2441-9.

49.

Lyn tyrosine kinase: accentuating the positive and the negative.

Xu Y, Harder KW, Huntington ND, Hibbs ML, Tarlinton DM.

Immunity. 2005 Jan;22(1):9-18. Review.

50.

Perturbed myelo/erythropoiesis in Lyn-deficient mice is similar to that in mice lacking the inhibitory phosphatases SHP-1 and SHIP-1.

Harder KW, Quilici C, Naik E, Inglese M, Kountouri N, Turner A, Zlatic K, Tarlinton DM, Hibbs ML.

Blood. 2004 Dec 15;104(13):3901-10. Epub 2004 Aug 31.

PMID:
15339845

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