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Items: 1 to 50 of 209

1.

Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antrum of Mice.

Matsuo J, Kimura S, Yamamura A, Koh CP, Hossain MZ, Heng DL, Kohu K, Voon DC, Hiai H, Unno M, So JB, Zhu F, Srivastava S, Teh M, Yeoh KG, Osato M, Ito Y.

Gastroenterology. 2017 Jan;152(1):218-231.e14. doi: 10.1053/j.gastro.2016.09.018. Epub 2016 Sep 23.

2.

Involvement of activation-induced cytidine deaminase in skin cancer development.

Nonaka T, Toda Y, Hiai H, Uemura M, Nakamura M, Yamamoto N, Asato R, Hattori Y, Bessho K, Minato N, Kinoshita K.

J Clin Invest. 2016 Apr 1;126(4):1367-82. doi: 10.1172/JCI81522. Epub 2016 Mar 14.

3.

Atopic dermatitis-like skin lesions with IgE hyperproduction and pruritus in KFRS4/Kyo rats.

Kuramoto T, Yokoe M, Tanaka D, Yuri A, Nishitani A, Higuchi Y, Yoshimi K, Tanaka M, Kuwamura M, Hiai H, Kabashima K, Serikawa T.

J Dermatol Sci. 2015 Nov;80(2):116-23. doi: 10.1016/j.jdermsci.2015.09.005. Epub 2015 Sep 21.

4.

Correction: Chronic Lung Injury by Constitutive Expression of Activation-Induced Cytidine Deaminase Leads to Focal Mucous Cell Metaplasia and Cancer.

Kitamura J, Uemura M, Kurozumi M, Sonobe M, Manabe T, Hiai H, Date H, Kinoshita K.

PLoS One. 2015 Aug 21;10(8):e0136807. doi: 10.1371/journal.pone.0136807. eCollection 2015. No abstract available.

5.

Chronic lung injury by constitutive expression of activation-induced cytidine deaminase leads to focal mucous cell metaplasia and cancer.

Kitamura J, Uemura M, Kurozumi M, Sonobe M, Manabe T, Hiai H, Date H, Kinoshita K.

PLoS One. 2015 Feb 6;10(2):e0117986. doi: 10.1371/journal.pone.0117986. eCollection 2015. Erratum in: PLoS One. 2015;10(8):e0136807.

6.

Expression of truncated PITX3 in the developing lens leads to microphthalmia and aphakia in mice.

Wada K, Matsushima Y, Tada T, Hasegawa S, Obara Y, Yoshizawa Y, Takahashi G, Hiai H, Shimanuki M, Suzuki S, Saitou J, Yamamoto N, Ichikawa M, Watanabe K, Kikkawa Y.

PLoS One. 2014 Oct 27;9(10):e111432. doi: 10.1371/journal.pone.0111432. eCollection 2014.

7.

Drosophila DOCK family protein sponge regulates the JNK pathway during thorax development.

Morishita K, Ozasa F, Eguchi K, Yoshioka Y, Yoshida H, Hiai H, Yamaguchi M.

Cell Struct Funct. 2014;39(2):113-24. Epub 2014 Oct 11.

8.
9.

Activation-induced cytidine deaminase is dispensable for virus-mediated liver and skin tumor development in mouse models.

Nguyen T, Xu J, Chikuma S, Hiai H, Kinoshita K, Moriya K, Koike K, Marcuzzi GP, Pfister H, Honjo T, Kobayashi M.

Int Immunol. 2014 Jul;26(7):397-406. doi: 10.1093/intimm/dxu040. Epub 2014 Feb 25.

PMID:
24569264
10.

Pthlh, a promising cancer modifier gene in rat tongue carcinogenesis.

Suwa H, Hirano M, Kawarada K, Nagayama M, Ehara M, Muraki T, Shisa H, Sugiyama A, Sugimoto M, Hiai H, Kitano M, Tanuma J.

Oncol Rep. 2014 Jan;31(1):3-12. doi: 10.3892/or.2013.2859. Epub 2013 Nov 20.

11.

The Drosophila DOCK family protein sponge is involved in differentiation of R7 photoreceptor cells.

Eguchi K, Yoshioka Y, Yoshida H, Morishita K, Miyata S, Hiai H, Yamaguchi M.

Exp Cell Res. 2013 Aug 15;319(14):2179-95. doi: 10.1016/j.yexcr.2013.05.024. Epub 2013 Jun 5.

PMID:
23747680
12.

Hereditary cataract of the Nakano mouse: Involvement of a hypomorphic mutation in the coproporphyrinogen oxidase gene.

Mori M, Gotoh S, Taketani S, Hiai H, Higuchi K.

Exp Eye Res. 2013 Jul;112:45-50. doi: 10.1016/j.exer.2013.04.005. Epub 2013 Apr 28.

PMID:
23631845
13.

Generation and characterization of severe combined immunodeficiency rats.

Mashimo T, Takizawa A, Kobayashi J, Kunihiro Y, Yoshimi K, Ishida S, Tanabe K, Yanagi A, Tachibana A, Hirose J, Yomoda J, Morimoto S, Kuramoto T, Voigt B, Watanabe T, Hiai H, Tateno C, Komatsu K, Serikawa T.

Cell Rep. 2012 Sep 27;2(3):685-94. doi: 10.1016/j.celrep.2012.08.009. Epub 2012 Sep 13.

14.

A rat model of hypohidrotic ectodermal dysplasia carries a missense mutation in the Edaradd gene.

Kuramoto T, Yokoe M, Hashimoto R, Hiai H, Serikawa T.

BMC Genet. 2011 Oct 21;12:91. doi: 10.1186/1471-2156-12-91.

15.

PD-1 deficiency results in the development of fatal myocarditis in MRL mice.

Wang J, Okazaki IM, Yoshida T, Chikuma S, Kato Y, Nakaki F, Hiai H, Honjo T, Okazaki T.

Int Immunol. 2010 Jun;22(6):443-52. doi: 10.1093/intimm/dxq026. Epub 2010 Apr 21.

PMID:
20410257
16.

Dual retrovirus integration tagging: identification of new signaling molecules Fiz1 and Hipk2 that are involved in the IL-7 signaling pathway in B lymphoblastic lymphomas.

Tsuruyama T, Imai Y, Takeuchi H, Hiratsuka T, Maruyama Y, Kanaya K, Kaszynski R, Jin G, Okuno T, Ozeki M, Nakamura T, Takakuwa T, Manabe T, Tamaki K, Hiai H.

J Leukoc Biol. 2010 Jul;88(1):107-16. doi: 10.1189/jlb.1109748. Epub 2010 Apr 1.

PMID:
20360400
17.

A quantitative trait locus responsible for inducing B-cell lymphoblastic lymphoma is a hotspot for microsatellite instability.

Kaszynski RH, Akatsuka S, Hiratsuka T, Jin G, Ozeki M, Okuno T, Nakamura T, Manabe T, Takakuwa T, Hiai H, Toyokuni S, Tamaki K, Tsuruyama T.

Cancer Sci. 2010 Mar;101(3):800-5. doi: 10.1111/j.1349-7006.2009.01437.x.

18.

FGFR4 polymorphism, TP53 mutation, and their combinations are prognostic factors for oral squamous cell carcinoma.

Tanuma J, Izumo T, Hirano M, Oyazato Y, Hori F, Umemura E, Shisa H, Hiai H, Kitano M.

Oncol Rep. 2010 Mar;23(3):739-44.

PMID:
20127014
19.

Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases.

Mashimo T, Takizawa A, Voigt B, Yoshimi K, Hiai H, Kuramoto T, Serikawa T.

PLoS One. 2010 Jan 25;5(1):e8870. doi: 10.1371/journal.pone.0008870.

20.

A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.

Takai A, Toyoshima T, Uemura M, Kitawaki Y, Marusawa H, Hiai H, Yamada S, Okazaki IM, Honjo T, Chiba T, Kinoshita K.

Oncogene. 2009 Jan 29;28(4):469-78. doi: 10.1038/onc.2008.415. Epub 2008 Nov 10.

PMID:
18997814
21.

The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transport.

Hara S, Kiyokawa E, Iemura S, Natsume T, Wassmer T, Cullen PJ, Hiai H, Matsuda M.

Mol Biol Cell. 2008 Sep;19(9):3823-35. doi: 10.1091/mbc.E08-03-0314. Epub 2008 Jul 2.

22.

Mutation of Dock5, a member of the guanine exchange factor Dock180 superfamily, in the rupture of lens cataract mouse.

Omi N, Kiyokawa E, Matsuda M, Kinoshita K, Yamada S, Yamada K, Matsushima Y, Wang Y, Kawai J, Suzuki M, Hayashizaki Y, Hiai H.

Exp Eye Res. 2008 May;86(5):828-34. doi: 10.1016/j.exer.2008.02.011. Epub 2008 Mar 2.

PMID:
18396277
23.

Bone marrow pre-B expansion by SL/Kh-Bomb1 locus: not sufficient for lymphomagenesis.

Hiratsuka T, Tsuruyama T, Kaszynski R, Kometani K, Minato N, Nakamura T, Tamaki K, Hiai H.

Leuk Res. 2008 Feb;32(2):309-14. Epub 2007 Jul 6.

PMID:
17617450
24.

Overexpression of a transcription factor LYL1 induces T- and B-cell lymphoma in mice.

Zhong Y, Jiang L, Hiai H, Toyokuni S, Yamada Y.

Oncogene. 2007 Oct 18;26(48):6937-47. Epub 2007 May 7.

PMID:
17486074
25.

Trisomy 10p and translocation of 10q to 4p associated with selective dysgenesis of IgA-producing cells in lymphoid tissue.

Saiga T, Hashimoto K, Kimura N, Ono H, Hiai H.

Pathol Int. 2007 Jan;57(1):37-42.

PMID:
17199741
26.
27.

Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b-/-Pdcd1-/- mice.

Okazaki T, Otaka Y, Wang J, Hiai H, Takai T, Ravetch JV, Honjo T.

J Exp Med. 2005 Dec 19;202(12):1643-8. Epub 2005 Dec 13.

28.

Increased intratumor Valpha24-positive natural killer T cells: a prognostic factor for primary colorectal carcinomas.

Tachibana T, Onodera H, Tsuruyama T, Mori A, Nagayama S, Hiai H, Imamura M.

Clin Cancer Res. 2005 Oct 15;11(20):7322-7.

29.

Genetic predisposition to 4NQO-induced tongue carcinogenesis in the rat.

Tanuma J, Hirano M, Hirayama Y, Semba I, Ogawa K, Shisa H, Hiai H, Kitano M.

Med Princ Pract. 2005 Sep-Oct;14(5):297-305.

30.

Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

Wang J, Yoshida T, Nakaki F, Hiai H, Okazaki T, Honjo T.

Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11823-8. Epub 2005 Aug 8.

31.
32.

A speed congenic rat strain bearing the tongue cancer susceptibility locus Tscc1 from Dark-Agouti rats.

Hirano M, Tanuma J, Hirayama Y, Ohyama M, Semba I, Wakusawa S, Shisa H, Hiai H, Kitano M.

Cancer Lett. 2006 Jan 18;231(2):185-91.

PMID:
15876484
33.

Use of a standard strain for external calibration in behavioral phenotyping.

Blizard DA, Wada Y, Onuki Y, Kato K, Mori T, Taniuchi T, Hosokawa H, Otobe T, Takahashi A, Shisa H, Hiai H, Makino J.

Behav Genet. 2005 May;35(3):323-32.

PMID:
15864447
34.

Two distinct mechanisms for loss of thioredoxin-binding protein-2 in oxidative stress-induced renal carcinogenesis.

Dutta KK, Nishinaka Y, Masutani H, Akatsuka S, Aung TT, Shirase T, Lee WH, Yamada Y, Hiai H, Yodoi J, Toyokuni S.

Lab Invest. 2005 Jun;85(6):798-807.

35.

Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis.

Matsuura M, Okazaki K, Nishio A, Nakase H, Tamaki H, Uchida K, Nishi T, Asada M, Kawasaki K, Fukui T, Yoshizawa H, Ohashi S, Inoue S, Kawanami C, Hiai H, Tabata Y, Chiba T.

Gastroenterology. 2005 Apr;128(4):975-86.

PMID:
15825079
37.

Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine.

Suzuki K, Fukui H, Kayahara T, Sawada M, Seno H, Hiai H, Kageyama R, Okano H, Chiba T.

Biochem Biophys Res Commun. 2005 Mar 4;328(1):348-52.

PMID:
15670790
38.

Development of spontaneous tumours and intestinal lesions in Fhit gene knockout mice.

Fujishita T, Doi Y, Sonoshita M, Hiai H, Oshima M, Huebner K, Croce CM, Taketo MM.

Br J Cancer. 2004 Oct 18;91(8):1571-4.

39.

Tissue distribution of Thorotrast and role of internal irradiation in carcinogenesis.

Yamasaki K, Yamasaki A, Tosaki M, Isozumi Y, Hiai H.

Oncol Rep. 2004 Oct;12(4):733-8.

PMID:
15375492
40.

Genetic resistance to chemical hepatocarcinogenesis in the DRH rat strain.

Higashi K, Denda A, Higashi T, Hiai H.

Comp Med. 2004 Aug;54(4):373-7. Review.

PMID:
15357316
41.

Regulatory mechanism of glutathione S-transferase P-form during chemical hepatocarcinogenesis: old wine in a new bottle.

Higashi K, Hiai H, Higashi T, Muramatsu M.

Cancer Lett. 2004 Jun 25;209(2):155-63. Review.

PMID:
15159017
42.

Arteriopathy in chronic allograft rejection in liver transplantation.

Miyagawa-Hayashino A, Tsuruyama T, Haga H, Oike F, Il-Deok K, Egawa H, Hiai H, Tanaka K, Manabe T.

Liver Transpl. 2004 Apr;10(4):513-9.

43.

Redox regulation of annexin 2 and its implications for oxidative stress-induced renal carcinogenesis and metastasis.

Tanaka T, Akatsuka S, Ozeki M, Shirase T, Hiai H, Toyokuni S.

Oncogene. 2004 May 13;23(22):3980-9.

PMID:
15048081
44.

Detection of glyceraldehyde 3-phosphate dehydrogenase messenger RNA using a peptide nucleic acid probe in paraffin-embedded archival specimens.

Hiroyasu M, Akatsuka S, Shirase T, Toda Y, Hiai H, Toyokuni S.

Pathol Int. 2004 Apr;54(4):251-5.

PMID:
15028026
45.

Immunogenetic analysis of gastric MALT lymphoma-like lesions induced by Helicobacter pylori infection in neonatally thymectomized mice.

Fukui T, Okazaki K, Tamaki H, Kawasaki K, Matsuura M, Asada M, Nishi T, Uchida K, Iwano M, Ohana M, Hiai H, Chiba T.

Lab Invest. 2004 Apr;84(4):485-92.

46.

Interaction of Helicobacter pylori-induced follicular gastritis and autoimmune gastritis in BALB/c mice with post-thymectomy autoimmune gastritis.

Okazaki K, Ohana M, Oshima C, Uchida K, Nishi T, Iwano M, Fukui T, Kawasaki K, Matsuura M, Asada M, Tamaki H, Hiai H, Chiba T.

J Gastroenterol. 2003;38(12):1131-7.

PMID:
14714249
47.

Effects of the phenolic contents of Mauritian endemic plant extracts on promoter activities of antioxidant enzymes.

Toyokuni S, Tanaka T, Kawaguchi W, Fang NR, Ozeki M, Akatsuka S, Hiai H, Aruoma OI, Bahorun T.

Free Radic Res. 2003 Nov;37(11):1215-24.

PMID:
14703734
48.

Expressions of junB and c-fos are enhanced in 4-nitroquinoline 1-oxide-induced rat tongue cancers.

Ohyama M, Hirayama Y, Tanuma J, Hirano M, Semba I, Shisa H, Hiai H, Sugihara K, Kitano M.

Pathol Int. 2004 Jan;54(1):35-40.

PMID:
14674993
49.

Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice.

Okazaki T, Tanaka Y, Nishio R, Mitsuiye T, Mizoguchi A, Wang J, Ishida M, Hiai H, Matsumori A, Minato N, Honjo T.

Nat Med. 2003 Dec;9(12):1477-83. Epub 2003 Nov 2.

PMID:
14595408
50.

Pre-B lymphomas in SL/Kh mice: a multifactorial disease model.

Hiai H, Tsuruyama T, Yamada Y.

Cancer Sci. 2003 Oct;94(10):847-50. Review.

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