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Items: 1 to 50 of 81

1.

Neuronal NO synthase mediates plenylephrine induced cardiomyocyte hypertrophy through facilitation of NFAT-dependent transcriptional activity.

Loyer X, Dubroca C, Branchereau M, Griffith G, Garcia L, Heymes C.

Biochem Biophys Rep. 2019 Mar 11;18:100620. doi: 10.1016/j.bbrep.2019.100620. eCollection 2019 Jul.

2.

Structural evidence for a new elaborate 3D-organization of the cardiomyocyte lateral membrane in adult mammalian cardiac tissues.

Guilbeau-Frugier C, Cauquil M, Karsenty C, Lairez O, Dambrin C, Payré B, Cassard H, Josse C, Seguelas MH, Allart S, Branchereau M, Heymes C, Mandel F, Delisle MB, Pathak A, Dague E, Sénard JM, Galés C.

Cardiovasc Res. 2019 May 1;115(6):1078-1091. doi: 10.1093/cvr/cvy256.

PMID:
30329023
3.

Publisher Correction: Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

Hoyles L, Fernández-Real JM, Federici M, Serino M, Abbott J, Charpentier J, Heymes C, Luque JL, Anthony E, Barton RH, Chilloux J, Myridakis A, Martinez-Gili L, Moreno-Navarrete JM, Benhamed F, Azalbert V, Blasco-Baque V, Puig J, Xifra G, Ricart W, Tomlinson C, Woodbridge M, Cardellini M, Davato F, Cardolini I, Porzio O, Gentileschi P, Lopez F, Foufelle F, Butcher SA, Holmes E, Nicholson JK, Postic C, Burcelin R, Dumas ME.

Nat Med. 2018 Oct;24(10):1628. doi: 10.1038/s41591-018-0169-5.

PMID:
30093731
4.

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

Hoyles L, Fernández-Real JM, Federici M, Serino M, Abbott J, Charpentier J, Heymes C, Luque JL, Anthony E, Barton RH, Chilloux J, Myridakis A, Martinez-Gili L, Moreno-Navarrete JM, Benhamed F, Azalbert V, Blasco-Baque V, Puig J, Xifra G, Ricart W, Tomlinson C, Woodbridge M, Cardellini M, Davato F, Cardolini I, Porzio O, Gentileschi P, Lopez F, Foufelle F, Butcher SA, Holmes E, Nicholson JK, Postic C, Burcelin R, Dumas ME.

Nat Med. 2018 Jul;24(7):1070-1080. doi: 10.1038/s41591-018-0061-3. Epub 2018 Jun 25. Erratum in: Nat Med. 2018 Aug 9;:.

5.

Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction.

Ngkelo A, Richart A, Kirk JA, Bonnin P, Vilar J, Lemitre M, Marck P, Branchereau M, Le Gall S, Renault N, Guerin C, Ranek MJ, Kervadec A, Danelli L, Gautier G, Blank U, Launay P, Camerer E, Bruneval P, Menasche P, Heymes C, Luche E, Casteilla L, Cousin B, Rodewald HR, Kass DA, Silvestre JS.

J Exp Med. 2016 Jun 27;213(7):1353-74. doi: 10.1084/jem.20160081.

6.

Erratum: Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.

Eden M, Meder B, Völkers M, Poomvanicha M, Domes K, Branchereau M, Marck P, Will R, Bernt A, Rangrez A, Busch M, Hrabě de Angelis M, Heymes C, Rottbauer W, Most P, Hofmann F, Frey N.

Nat Commun. 2016 May 26;7:11835. doi: 10.1038/ncomms11835. No abstract available.

7.

Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.

Eden M, Meder B, Völkers M, Poomvanicha M, Domes K, Branchereau M, Marck P, Will R, Bernt A, Rangrez A, Busch M; German Mouse Clinic Consortium, Hrabě de Angelis M, Heymes C, Rottbauer W, Most P, Hofmann F, Frey N.

Nat Commun. 2016 Apr 28;7:11317. doi: 10.1315/11317. Erratum in: Nat Commun. 2016 May 26;7:11835.

8.

Periodontal dysbiosis linked to periodontitis is associated with cardiometabolic adaptation to high-fat diet in mice.

Branchereau M, Reichardt F, Loubieres P, Marck P, Waget A, Azalbert V, Colom A, Padmanabhan R, Iacovoni JS, Giry A, Tercé F, Heymes C, Burcelin R, Serino M, Blasco-Baque V.

Am J Physiol Gastrointest Liver Physiol. 2016 Jun 1;310(11):G1091-101. doi: 10.1152/ajpgi.00424.2015. Epub 2016 Mar 31.

9.

NOS1 induces NADPH oxidases and impairs contraction kinetics in aged murine ventricular myocytes.

Villmow M, Klöckner U, Heymes C, Gekle M, Rueckschloss U.

Basic Res Cardiol. 2015 Sep;110(5):506. doi: 10.1007/s00395-015-0506-5. Epub 2015 Jul 15.

PMID:
26173391
10.

The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORγt and Controls Metabolic Disease.

Garidou L, Pomié C, Klopp P, Waget A, Charpentier J, Aloulou M, Giry A, Serino M, Stenman L, Lahtinen S, Dray C, Iacovoni JS, Courtney M, Collet X, Amar J, Servant F, Lelouvier B, Valet P, Eberl G, Fazilleau N, Douin-Echinard V, Heymes C, Burcelin R.

Cell Metab. 2015 Jul 7;22(1):100-12. doi: 10.1016/j.cmet.2015.06.001.

11.

Obligatory role of neuronal nitric oxide synthase in the heart's antioxidant adaptation with exercise.

Roof SR, Ho HT, Little SC, Ostler JE, Brundage EA, Periasamy M, Villamena FA, Györke S, Biesiadecki BJ, Heymes C, Houser SR, Davis JP, Ziolo MT.

J Mol Cell Cardiol. 2015 Apr;81:54-61. doi: 10.1016/j.yjmcc.2015.01.003. Epub 2015 Jan 14.

12.

Human white and brite adipogenesis is supported by MSCA1 and is impaired by immune cells.

Estève D, Boulet N, Volat F, Zakaroff-Girard A, Ledoux S, Coupaye M, Decaunes P, Belles C, Gaits-Iacovoni F, Iacovoni JS, Rémaury A, Castel B, Ferrara P, Heymes C, Lafontan M, Bouloumié A, Galitzky J.

Stem Cells. 2015 Apr;33(4):1277-91. doi: 10.1002/stem.1916.

13.

Exchange protein directly activated by cAMP 1 promotes autophagy during cardiomyocyte hypertrophy.

Laurent AC, Bisserier M, Lucas A, Tortosa F, Roumieux M, De Régibus A, Swiader A, Sainte-Marie Y, Heymes C, Vindis C, Lezoualc'h F.

Cardiovasc Res. 2015 Jan 1;105(1):55-64. doi: 10.1093/cvr/cvu242. Epub 2014 Nov 19.

PMID:
25411381
14.

Carabin protects against cardiac hypertrophy by blocking calcineurin, Ras, and Ca2+/calmodulin-dependent protein kinase II signaling.

Bisserier M, Berthouze-Duquesnes M, Breckler M, Tortosa F, Fazal L, de Régibus A, Laurent AC, Varin A, Lucas A, Branchereau M, Marck P, Schickel JN, Deloménie C, Cazorla O, Soulas-Sprauel P, Crozatier B, Morel E, Heymes C, Lezoualc'h F.

Circulation. 2015 Jan 27;131(4):390-400; discussion 400. doi: 10.1161/CIRCULATIONAHA.114.010686. Epub 2014 Nov 4.

PMID:
25369805
15.

Atomic force and electron microscopic-based study of sarcolemmal surface of living cardiomyocytes unveils unexpected mitochondrial shift in heart failure.

Dague E, Genet G, Lachaize V, Guilbeau-Frugier C, Fauconnier J, Mias C, Payré B, Chopinet L, Alsteens D, Kasas S, Severac C, Thireau J, Heymes C, Honton B, Lacampagne A, Pathak A, Sénard JM, Galés C.

J Mol Cell Cardiol. 2014 Sep;74:162-72. doi: 10.1016/j.yjmcc.2014.05.006. Epub 2014 May 17.

PMID:
24839910
16.

[Impact of periodontal disease on arterial pressure in diabetic mice].

Blasco-Baque V, Kémoun P, Loubieres P, Roumieux M, Heymes C, Serino M, Sixou M, Burcelin R.

Ann Cardiol Angeiol (Paris). 2012 Jun;61(3):173-7. doi: 10.1016/j.ancard.2012.04.012. Epub 2012 May 7. French.

PMID:
22621847
17.

Abnormal plasma microparticles impair vasoconstrictor responses in patients with cirrhosis.

Rautou PE, Bresson J, Sainte-Marie Y, Vion AC, Paradis V, Renard JM, Devue C, Heymes C, Letteron P, Elkrief L, Lebrec D, Valla D, Tedgui A, Moreau R, Boulanger CM.

Gastroenterology. 2012 Jul;143(1):166-76.e6. doi: 10.1053/j.gastro.2012.03.040. Epub 2012 Mar 30.

PMID:
22465620
18.

Ephrin-B1 is a novel specific component of the lateral membrane of the cardiomyocyte and is essential for the stability of cardiac tissue architecture cohesion.

Genet G, Guilbeau-Frugier C, Honton B, Dague E, Schneider MD, Coatrieux C, Calise D, Cardin C, Nieto C, Payré B, Dubroca C, Marck P, Heymes C, Dubrac A, Arvanitis D, Despas F, Altié MF, Seguelas MH, Delisle MB, Davy A, Sénard JM, Pathak A, Galés C.

Circ Res. 2012 Mar 2;110(5):688-700. doi: 10.1161/CIRCRESAHA.111.262451. Epub 2012 Feb 2.

19.

ACE inhibition prevents diastolic Ca2+ overload and loss of myofilament Ca2+ sensitivity after myocardial infarction.

Zalvidea S, André L, Loyer X, Cassan C, Sainte-Marie Y, Thireau J, Sjaastad I, Heymes C, Pasquié JL, Cazorla O, Aimond F, Richard S.

Curr Mol Med. 2012 Feb;12(2):206-17.

20.

C/EBP homologous protein-10 (CHOP-10) limits postnatal neovascularization through control of endothelial nitric oxide synthase gene expression.

Loinard C, Zouggari Y, Rueda P, Ramkhelawon B, Cochain C, Vilar J, Récalde A, Richart A, Charue D, Duriez M, Mori M, Arenzana-Seisdedos F, Lévy BI, Heymes C, Silvestre JS.

Circulation. 2012 Feb 28;125(8):1014-26. doi: 10.1161/CIRCULATIONAHA.111.041830. Epub 2012 Jan 20.

PMID:
22265908
21.

Decreased expression and activity of cAMP phosphodiesterases in cardiac hypertrophy and its impact on beta-adrenergic cAMP signals.

Abi-Gerges A, Richter W, Lefebvre F, Mateo P, Varin A, Heymes C, Samuel JL, Lugnier C, Conti M, Fischmeister R, Vandecasteele G.

Circ Res. 2009 Oct 9;105(8):784-92. doi: 10.1161/CIRCRESAHA.109.197947. Epub 2009 Sep 10.

22.

Red wine polyphenols prevent metabolic and cardiovascular alterations associated with obesity in Zucker fatty rats (Fa/Fa).

Agouni A, Lagrue-Lak-Hal AH, Mostefai HA, Tesse A, Mulder P, Rouet P, Desmoulin F, Heymes C, Martínez MC, Andriantsitohaina R.

PLoS One. 2009;4(5):e5557. doi: 10.1371/journal.pone.0005557. Epub 2009 May 18.

23.

Involvement of beta 3-adrenoceptor in altered beta-adrenergic response in senescent heart: role of nitric oxide synthase 1-derived nitric oxide.

Birenbaum A, Tesse A, Loyer X, Michelet P, Andriantsitohaina R, Heymes C, Riou B, Amour J.

Anesthesiology. 2008 Dec;109(6):1045-53. doi: 10.1097/ALN.0b013e31818d7e5a.

PMID:
19034101
24.

Preservation of the positive lusitropic effect of beta-adrenoceptors stimulation in diabetic cardiomyopathy.

Amour J, Loyer X, Michelet P, Birenbaum A, Riou B, Heymes C.

Anesth Analg. 2008 Oct;107(4):1130-8. doi: 10.1213/ane.0b013e3181806903.

PMID:
18806014
25.

Endothelial dysfunction caused by circulating microparticles from patients with metabolic syndrome.

Agouni A, Lagrue-Lak-Hal AH, Ducluzeau PH, Mostefai HA, Draunet-Busson C, Leftheriotis G, Heymes C, Martinez MC, Andriantsitohaina R.

Am J Pathol. 2008 Oct;173(4):1210-9. doi: 10.2353/ajpath.2008.080228. Epub 2008 Sep 4.

26.

Circulating microparticles from patients with septic shock exert protective role in vascular function.

Mostefai HA, Meziani F, Mastronardi ML, Agouni A, Heymes C, Sargentini C, Asfar P, Martinez MC, Andriantsitohaina R.

Am J Respir Crit Care Med. 2008 Dec 1;178(11):1148-55. doi: 10.1164/rccm.200712-1835OC. Epub 2008 Aug 21.

PMID:
18723433
27.

Cardiomyocyte overexpression of neuronal nitric oxide synthase delays transition toward heart failure in response to pressure overload by preserving calcium cycling.

Loyer X, Gómez AM, Milliez P, Fernandez-Velasco M, Vangheluwe P, Vinet L, Charue D, Vaudin E, Zhang W, Sainte-Marie Y, Robidel E, Marty I, Mayer B, Jaisser F, Mercadier JJ, Richard S, Shah AM, Bénitah JP, Samuel JL, Heymes C.

Circulation. 2008 Jun 24;117(25):3187-98. doi: 10.1161/CIRCULATIONAHA.107.741702. Epub 2008 Jun 9.

PMID:
18541744
28.

Phosphatidylinositol 3-kinase and xanthine oxidase regulate nitric oxide and reactive oxygen species productions by apoptotic lymphocyte microparticles in endothelial cells.

Mostefai HA, Agouni A, Carusio N, Mastronardi ML, Heymes C, Henrion D, Andriantsitohaina R, Martinez MC.

J Immunol. 2008 Apr 1;180(7):5028-35.

29.

Tissue kallikrein deficiency aggravates cardiac remodelling and decreases survival after myocardial infarction in mice.

Pons S, Griol-Charhbili V, Heymes C, Fornes P, Heudes D, Hagege A, Loyer X, Meneton P, Giudicelli JF, Samuel JL, Alhenc-Gelas F, Richer C.

Eur J Heart Fail. 2008 Apr;10(4):343-51. doi: 10.1016/j.ejheart.2008.02.002. Epub 2008 Mar 14.

30.

Epac mediates beta-adrenergic receptor-induced cardiomyocyte hypertrophy.

Métrich M, Lucas A, Gastineau M, Samuel JL, Heymes C, Morel E, Lezoualc'h F.

Circ Res. 2008 Apr 25;102(8):959-65. doi: 10.1161/CIRCRESAHA.107.164947. Epub 2008 Mar 6.

PMID:
18323524
31.

Constitutive nitric oxide synthases in the heart from hypertrophy to failure.

Loyer X, Heymes C, Samuel JL.

Clin Exp Pharmacol Physiol. 2008 Apr;35(4):483-8. doi: 10.1111/j.1440-1681.2008.04901.x. Review.

PMID:
18307746
32.

Effect of long-term heart rate reduction by If current inhibition on pressure overload-induced heart failure in rats.

Ciobotaru V, Heimburger M, Louedec L, Heymes C, Ventura-Clapier R, Bedossa P, Escoubet B, Michel JB, Mercadier JJ, Logeart D.

J Pharmacol Exp Ther. 2008 Jan;324(1):43-9. Epub 2007 Sep 27.

PMID:
17901295
33.

Effects of sex differences on constitutive nitric oxide synthase expression and activity in response to pressure overload in rats.

Loyer X, Oliviero P, Damy T, Robidel E, Marotte F, Heymes C, Samuel JL.

Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H2650-8. Epub 2007 Sep 21.

34.

Altered contractile response due to increased beta3-adrenoceptor stimulation in diabetic cardiomyopathy: the role of nitric oxide synthase 1-derived nitric oxide.

Amour J, Loyer X, Le Guen M, Mabrouk N, David JS, Camors E, Carusio N, Vivien B, Andriantsitohaina R, Heymes C, Riou B.

Anesthesiology. 2007 Sep;107(3):452-60.

PMID:
17721248
35.

17beta-estradiol regulates constitutive nitric oxide synthase expression differentially in the myocardium in response to pressure overload.

Loyer X, Damy T, Chvojkova Z, Robidel E, Marotte F, Oliviero P, Heymes C, Samuel JL.

Endocrinology. 2007 Oct;148(10):4579-84. Epub 2007 Aug 2.

PMID:
17673519
36.

Levosimendan restores both systolic and diastolic cardiac performance in lipopolysaccharide-treated rabbits: comparison with dobutamine and milrinone.

Barraud D, Faivre V, Damy T, Welschbillig S, Gayat E, Heymes C, Payen D, Shah AM, Mebazaa A.

Crit Care Med. 2007 May;35(5):1376-82.

PMID:
17414729
37.

RhoA activation and interaction with Caveolin-1 are critical for pressure-induced myogenic tone in rat mesenteric resistance arteries.

Dubroca C, Loyer X, Retailleau K, Loirand G, Pacaud P, Feron O, Balligand JL, Lévy BI, Heymes C, Henrion D.

Cardiovasc Res. 2007 Jan 1;73(1):190-7. Epub 2006 Nov 10.

PMID:
17150200
38.

NADPH oxidase-derived overproduction of reactive oxygen species impairs postischemic neovascularization in mice with type 1 diabetes.

Ebrahimian TG, Heymes C, You D, Blanc-Brude O, Mees B, Waeckel L, Duriez M, Vilar J, Brandes RP, Levy BI, Shah AM, Silvestre JS.

Am J Pathol. 2006 Aug;169(2):719-28.

39.

Cardiac myocyte neuronal nitric oxide synthase. New therapeutic target in heart failure?

Loyer X, Samuel JL, Heymes C.

Arch Mal Coeur Vaiss. 2005 Dec;98(12):1244-8. Review.

PMID:
16435605
40.

[Myocardial effects of nitric oxide, NO. Clinical and experimental evidence].

Heymes C, Swynghedauw B, Samuel JL.

Bull Acad Natl Med. 2005 May;189(5):893-901; discussion 901. French.

PMID:
16433461
41.

Role of myocardial neuronal nitric oxide synthase-derived nitric oxide in beta-adrenergic hyporesponsiveness after myocardial infarction-induced heart failure in rat.

Bendall JK, Damy T, Ratajczak P, Loyer X, Monceau V, Marty I, Milliez P, Robidel E, Marotte F, Samuel JL, Heymes C.

Circulation. 2004 Oct 19;110(16):2368-75. Epub 2004 Oct 4.

PMID:
15466641
42.

Evidence for altered interleukin 18 (IL)-18 pathway in human heart failure.

Mallat Z, Heymes C, Corbaz A, Logeart D, Alouani S, Cohen-Solal A, Seidler T, Hasenfuss G, Chvatchko Y, Shah AM, Tedgui A.

FASEB J. 2004 Nov;18(14):1752-4. Epub 2004 Sep 15.

PMID:
15371332
43.

Cardiac specific increase in aldosterone production induces coronary dysfunction in aldosterone synthase-transgenic mice.

Garnier A, Bendall JK, Fuchs S, Escoubet B, Rochais F, Hoerter J, Nehme J, Ambroisine ML, De Angelis N, Morineau G, d'Estienne P, Fischmeister R, Heymes C, Pinet F, Delcayre C.

Circulation. 2004 Sep 28;110(13):1819-25. Epub 2004 Sep 13.

PMID:
15364804
44.

Aldosterone-synthase overexpression in heart: a tool to explore aldosterone's effects.

Heymes C, Garnier A, Fuchs S, Bendall JK, Nehme J, Ambroisine ML, Robidel E, Swynghedauw B, Milliez P, Delcayre C.

Mol Cell Endocrinol. 2004 Mar 31;217(1-2):213-9. Review.

PMID:
15134820
45.

Increased neuronal nitric oxide synthase-derived NO production in the failing human heart.

Damy T, Ratajczak P, Shah AM, Camors E, Marty I, Hasenfuss G, Marotte F, Samuel JL, Heymes C.

Lancet. 2004 Apr 24;363(9418):1365-7.

PMID:
15110495
46.

Up-regulation of cardiac nitric oxide synthase 1-derived nitric oxide after myocardial infarction in senescent rats.

Damy T, Ratajczak P, Robidel E, Bendall JK, Oliviéro P, Boczkowski J, Ebrahimian T, Marotte F, Samuel JL, Heymes C.

FASEB J. 2003 Oct;17(13):1934-6. Epub 2003 Aug 1.

PMID:
12897062
47.

Increased myocardial NADPH oxidase activity in human heart failure.

Heymes C, Bendall JK, Ratajczak P, Cave AC, Samuel JL, Hasenfuss G, Shah AM.

J Am Coll Cardiol. 2003 Jun 18;41(12):2164-71.

48.

Extracellular matrix and cardiac remodelling.

Bendall JK, Heymes C, Ratajczak P, Samuel JL.

Arch Mal Coeur Vaiss. 2002 Dec;95(12):1226-9. Review.

PMID:
12611045
49.

Caveolin-1 and -3 dissociations from caveolae to cytosol in the heart during aging and after myocardial infarction in rat.

Ratajczak P, Damy T, Heymes C, Oliviéro P, Marotte F, Robidel E, Sercombe R, Boczkowski J, Rappaport L, Samuel JL.

Cardiovasc Res. 2003 Feb;57(2):358-69.

PMID:
12566108
50.

Myocardial fibrosis blunts nitric oxide synthase-related preload reserve in human dilated cardiomyopathy.

Bronzwaer JG, Heymes C, Visser CA, Paulus WJ.

Am J Physiol Heart Circ Physiol. 2003 Jan;284(1):H10-6.

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