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Items: 38

1.

Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis.

Puelles VG, Fleck D, Ortz L, Papadouri S, Strieder T, Böhner AMC, van der Wolde JW, Vogt M, Saritas T, Kuppe C, Fuss A, Menzel S, Klinkhammer BM, Müller-Newen G, Heymann F, Decker L, Braun F, Kretz O, Huber TB, Susaki EA, Ueda HR, Boor P, Floege J, Kramann R, Kurts C, Bertram JF, Spehr M, Nikolic-Paterson DJ, Moeller MJ.

Kidney Int. 2019 Mar 15. pii: S0085-2538(19)30318-7. doi: 10.1016/j.kint.2019.02.034. [Epub ahead of print]

PMID:
31155155
2.

Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo.

Ergen C, Niemietz PM, Heymann F, Baues M, Gremse F, Pola R, van Bloois L, Storm G, Kiessling F, Trautwein C, Luedde T, Lammers T, Tacke F.

Biomaterials. 2019 Jun;206:49-60. doi: 10.1016/j.biomaterials.2019.03.025. Epub 2019 Mar 22.

PMID:
30925288
3.

CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4+ T-Cell-Dependent Control of Senescence.

Mossanen JC, Kohlhepp M, Wehr A, Krenkel O, Liepelt A, Roeth AA, Möckel D, Heymann F, Lammers T, Gassler N, Hermann J, Jankowski J, Neumann UP, Luedde T, Trautwein C, Tacke F.

Gastroenterology. 2019 May;156(6):1877-1889.e4. doi: 10.1053/j.gastro.2019.01.247. Epub 2019 Jan 30.

PMID:
30710528
4.

Polypropylene mesh implantation for hernia repair causes myeloid cell-driven persistent inflammation.

Heymann F, von Trotha KT, Preisinger C, Lynen-Jansen P, Roeth AA, Geiger M, Geisler LJ, Frank AK, Conze J, Luedde T, Trautwein C, Binnebösel M, Neumann UP, Tacke F.

JCI Insight. 2019 Jan 24;4(2). pii: 123862. doi: 10.1172/jci.insight.123862. [Epub ahead of print]

5.

Intestinal Microbiota Protects against MCD Diet-Induced Steatohepatitis.

Schneider KM, Mohs A, Kilic K, Candels LS, Elfers C, Bennek E, Schneider LB, Heymann F, Gassler N, Penders J, Trautwein C.

Int J Mol Sci. 2019 Jan 14;20(2). pii: E308. doi: 10.3390/ijms20020308.

6.

CX3CR1 modulates the anti-inflammatory activity of hepatic dendritic cells in response to acute liver injury.

Sutti S, Heymann F, Bruzzì S, Peusquens J, Trautwein C, Albano E, Tacke F.

Clin Sci (Lond). 2017 Jul 24. pii: CS20171025. doi: 10.1042/CS20171025. [Epub ahead of print]

PMID:
28739980
7.

Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles.

Ergen C, Heymann F, Al Rawashdeh W, Gremse F, Bartneck M, Panzer U, Pola R, Pechar M, Storm G, Mohr N, Barz M, Zentel R, Kiessling F, Trautwein C, Lammers T, Tacke F.

Biomaterials. 2017 Jan;114:106-120. doi: 10.1016/j.biomaterials.2016.11.009. Epub 2016 Nov 9.

PMID:
27855336
8.

Chemokine (C-C motif) receptor 2-positive monocytes aggravate the early phase of acetaminophen-induced acute liver injury.

Mossanen JC, Krenkel O, Ergen C, Govaere O, Liepelt A, Puengel T, Heymann F, Kalthoff S, Lefebvre E, Eulberg D, Luedde T, Marx G, Strassburg CP, Roskams T, Trautwein C, Tacke F.

Hepatology. 2016 Nov;64(5):1667-1682. doi: 10.1002/hep.28682. Epub 2016 Jul 22.

PMID:
27302828
9.

Regardless of etiology, progressive renal disease causes ultrastructural and functional alterations of peritubular capillaries.

Bábíčková J, Klinkhammer BM, Buhl EM, Djudjaj S, Hoss M, Heymann F, Tacke F, Floege J, Becker JU, Boor P.

Kidney Int. 2017 Jan;91(1):70-85. doi: 10.1016/j.kint.2016.07.038. Epub 2016 Sep 24.

PMID:
27678159
10.

The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance.

Gautheron J, Vucur M, Schneider AT, Severi I, Roderburg C, Roy S, Bartneck M, Schrammen P, Diaz MB, Ehling J, Gremse F, Heymann F, Koppe C, Lammers T, Kiessling F, Van Best N, Pabst O, Courtois G, Linkermann A, Krautwald S, Neumann UP, Tacke F, Trautwein C, Green DR, Longerich T, Frey N, Luedde M, Bluher M, Herzig S, Heikenwalder M, Luedde T.

Nat Commun. 2016 Jun 21;7:11869. doi: 10.1038/ncomms11869.

11.

Immunology in the liver--from homeostasis to disease.

Heymann F, Tacke F.

Nat Rev Gastroenterol Hepatol. 2016 Feb;13(2):88-110. doi: 10.1038/nrgastro.2015.200. Epub 2016 Jan 13. Review.

PMID:
26758786
12.

M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment.

Van Overmeire E, Stijlemans B, Heymann F, Keirsse J, Morias Y, Elkrim Y, Brys L, Abels C, Lahmar Q, Ergen C, Vereecke L, Tacke F, De Baetselier P, Van Ginderachter JA, Laoui D.

Cancer Res. 2016 Jan 1;76(1):35-42. doi: 10.1158/0008-5472.CAN-15-0869. Epub 2015 Nov 16.

13.

Isolation and time lapse microscopy of highly pure hepatic stellate cells.

Bartneck M, Warzecha KT, Tag CG, Sauer-Lehnen S, Heymann F, Trautwein C, Weiskirchen R, Tacke F.

Anal Cell Pathol (Amst). 2015;2015:417023. doi: 10.1155/2015/417023. Epub 2015 Jul 16.

14.

CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis.

Schneider KM, Bieghs V, Heymann F, Hu W, Dreymueller D, Liao L, Frissen M, Ludwig A, Gassler N, Pabst O, Latz E, Sellge G, Penders J, Tacke F, Trautwein C.

Hepatology. 2015 Nov;62(5):1405-16. doi: 10.1002/hep.27982. Epub 2015 Sep 2.

PMID:
26178698
15.

[Typical patterns of depressive disorders during outpatient psychotherapy and their prediction].

Altmann U, Steyer R, Kramer D, Steffanowski A, Wittmann WW, Heymann Fv, Auch-Dorsch E, Bruckmayer E, Pfaffinger I, Fembacher A, Strauß B.

Z Psychosom Med Psychother. 2015;61(2):156-72. doi: 10.13109/zptm.2015.61.2.156. German.

PMID:
26175171
16.

IL-6 Trans-Signaling Drives Murine Crescentic GN.

Braun GS, Nagayama Y, Maruta Y, Heymann F, van Roeyen CR, Klinkhammer BM, Boor P, Villa L, Salant DJ, Raffetseder U, Rose-John S, Ostendorf T, Floege J.

J Am Soc Nephrol. 2016 Jan;27(1):132-42. doi: 10.1681/ASN.2014111147. Epub 2015 Jun 3.

17.

Long term intravital multiphoton microscopy imaging of immune cells in healthy and diseased liver using CXCR6.Gfp reporter mice.

Heymann F, Niemietz PM, Peusquens J, Ergen C, Kohlhepp M, Mossanen JC, Schneider C, Vogt M, Tolba RH, Trautwein C, Martin C, Tacke F.

J Vis Exp. 2015 Mar 24;(97). doi: 10.3791/52607.

18.

The concanavalin A model of acute hepatitis in mice.

Heymann F, Hamesch K, Weiskirchen R, Tacke F.

Lab Anim. 2015 Apr;49(1 Suppl):12-20. doi: 10.1177/0023677215572841.

PMID:
25835734
19.

Liver inflammation abrogates immunological tolerance induced by Kupffer cells.

Heymann F, Peusquens J, Ludwig-Portugall I, Kohlhepp M, Ergen C, Niemietz P, Martin C, van Rooijen N, Ochando JC, Randolph GJ, Luedde T, Ginhoux F, Kurts C, Trautwein C, Tacke F.

Hepatology. 2015 Jul;62(1):279-91. doi: 10.1002/hep.27793. Epub 2015 Apr 22.

PMID:
25810240
20.

CC Chemokine Ligand 18 in ANCA-Associated Crescentic GN.

Brix SR, Stege G, Disteldorf E, Hoxha E, Krebs C, Krohn S, Otto B, Klätschke K, Herden E, Heymann F, Lira SA, Tacke F, Wolf G, Busch M, Jabs WJ, Özcan F, Keller F, Beige J, Wagner K, Helmchen U, Noriega M, Wiech T, Panzer U, Stahl RA.

J Am Soc Nephrol. 2015 Sep;26(9):2105-17. doi: 10.1681/ASN.2014040407. Epub 2015 Mar 11.

21.

Translation control of TAK1 mRNA by hnRNP K modulates LPS-induced macrophage activation.

Liepelt A, Mossanen JC, Denecke B, Heymann F, De Santis R, Tacke F, Marx G, Ostareck DH, Ostareck-Lederer A.

RNA. 2014 Jun;20(6):899-911. doi: 10.1261/rna.042788.113. Epub 2014 Apr 21.

22.

Pharmacological inhibition of the chemokine C-C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly-6C(+) macrophage infiltration in mice.

Baeck C, Wei X, Bartneck M, Fech V, Heymann F, Gassler N, Hittatiya K, Eulberg D, Luedde T, Trautwein C, Tacke F.

Hepatology. 2014 Mar;59(3):1060-72. doi: 10.1002/hep.26783. Epub 2014 Jan 30.

PMID:
24481979
23.

Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis.

Hammerich L, Bangen JM, Govaere O, Zimmermann HW, Gassler N, Huss S, Liedtke C, Prinz I, Lira SA, Luedde T, Roskams T, Trautwein C, Heymann F, Tacke F.

Hepatology. 2014 Feb;59(2):630-42. doi: 10.1002/hep.26697. Epub 2013 Dec 23.

24.

YB-1 is an early and central mediator of bacterial and sterile inflammation in vivo.

Hanssen L, Alidousty C, Djudjaj S, Frye BC, Rauen T, Boor P, Mertens PR, van Roeyen CR, Tacke F, Heymann F, Tittel AP, Koch A, Floege J, Ostendorf T, Raffetseder U.

J Immunol. 2013 Sep 1;191(5):2604-13. doi: 10.4049/jimmunol.1300416. Epub 2013 Jul 19.

25.

Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis.

Wehr A, Baeck C, Heymann F, Niemietz PM, Hammerich L, Martin C, Zimmermann HW, Pack O, Gassler N, Hittatiya K, Ludwig A, Luedde T, Trautwein C, Tacke F.

J Immunol. 2013 May 15;190(10):5226-36. doi: 10.4049/jimmunol.1202909. Epub 2013 Apr 17.

26.

Peptide-functionalized gold nanorods increase liver injury in hepatitis.

Bartneck M, Ritz T, Keul HA, Wambach M, Bornemann J, Gbureck U, Ehling J, Lammers T, Heymann F, Gassler N, Lüdde T, Trautwein C, Groll J, Tacke F.

ACS Nano. 2012 Oct 23;6(10):8767-77. doi: 10.1021/nn302502u. Epub 2012 Oct 1.

PMID:
22994679
27.

Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice.

Heymann F, Hammerich L, Storch D, Bartneck M, Huss S, Rüsseler V, Gassler N, Lira SA, Luedde T, Trautwein C, Tacke F.

Hepatology. 2012 Mar;55(3):898-909. doi: 10.1002/hep.24764. Epub 2012 Jan 13.

28.

[Prevalence and comorbidity of somatoform disorder in psychosomatic inpatients: a multicentre study].

Pieh C, Lahmann C, Heymann FV, Tritt K, Loew T, Busch V, Probst T.

Z Psychosom Med Psychother. 2011;57(3):244-50. German.

PMID:
21968937
29.

Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury.

Baeck C, Wehr A, Karlmark KR, Heymann F, Vucur M, Gassler N, Huss S, Klussmann S, Eulberg D, Luedde T, Trautwein C, Tacke F.

Gut. 2012 Mar;61(3):416-26. doi: 10.1136/gutjnl-2011-300304. Epub 2011 Aug 3.

PMID:
21813474
30.

Role of IL-17 and Th17 cells in liver diseases.

Hammerich L, Heymann F, Tacke F.

Clin Dev Immunol. 2011;2011:345803. doi: 10.1155/2011/345803. Epub 2010 Dec 15. Review.

31.

Kidney Dendritic Cells Become Pathogenic during Crescentic Glomerulonephritis with Proteinuria.

Hochheiser K, Engel DR, Hammerich L, Heymann F, Knolle PA, Panzer U, Kurts C.

J Am Soc Nephrol. 2011 Feb;22(2):306-16. doi: 10.1681/ASN.2010050548. Epub 2010 Dec 16.

32.

TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer.

Bettermann K, Vucur M, Haybaeck J, Koppe C, Janssen J, Heymann F, Weber A, Weiskirchen R, Liedtke C, Gassler N, Müller M, de Vos R, Wolf MJ, Boege Y, Seleznik GM, Zeller N, Erny D, Fuchs T, Zoller S, Cairo S, Buendia MA, Prinz M, Akira S, Tacke F, Heikenwalder M, Trautwein C, Luedde T.

Cancer Cell. 2010 May 18;17(5):481-96. doi: 10.1016/j.ccr.2010.03.021.

33.

Monocytes and macrophages as cellular targets in liver fibrosis.

Heymann F, Trautwein C, Tacke F.

Inflamm Allergy Drug Targets. 2009 Sep;8(4):307-18. Review.

PMID:
19534673
34.

Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury.

Heymann F, Meyer-Schwesinger C, Hamilton-Williams EE, Hammerich L, Panzer U, Kaden S, Quaggin SE, Floege J, Gröne HJ, Kurts C.

J Clin Invest. 2009 May;119(5):1286-97. doi: 10.1172/JCI38399. Epub 2009 Apr 20. Erratum in: J Clin Invest. 2009 Jul;119(7):2114.

35.

The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis.

Paust HJ, Turner JE, Steinmetz OM, Peters A, Heymann F, Hölscher C, Wolf G, Kurts C, Mittrücker HW, Stahl RA, Panzer U.

J Am Soc Nephrol. 2009 May;20(5):969-79. doi: 10.1681/ASN.2008050556. Epub 2009 Apr 1.

36.

CCR5 deficiency aggravates crescentic glomerulonephritis in mice.

Turner JE, Paust HJ, Steinmetz OM, Peters A, Meyer-Schwesinger C, Heymann F, Helmchen U, Fehr S, Horuk R, Wenzel U, Kurts C, Mittrücker HW, Stahl RA, Panzer U.

J Immunol. 2008 Nov 1;181(9):6546-56.

37.

Role of T cells and dendritic cells in glomerular immunopathology.

Kurts C, Heymann F, Lukacs-Kornek V, Boor P, Floege J.

Semin Immunopathol. 2007 Nov;29(4):317-35. Epub 2007 Oct 23. Review.

PMID:
17955242
38.

Chemokine receptor CXCR3 mediates T cell recruitment and tissue injury in nephrotoxic nephritis in mice.

Panzer U, Steinmetz OM, Paust HJ, Meyer-Schwesinger C, Peters A, Turner JE, Zahner G, Heymann F, Kurts C, Hopfer H, Helmchen U, Haag F, Schneider A, Stahl RA.

J Am Soc Nephrol. 2007 Jul;18(7):2071-84. Epub 2007 May 30.

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