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Items: 13

1.

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.

Wong JB, Hewitt SL, Heltemes-Harris LM, Mandal M, Johnson K, Rajewsky K, Koralov SB, Clark MR, Farrar MA, Skok JA.

Nat Commun. 2019 Oct 18;10(1):4768. doi: 10.1038/s41467-019-12824-z.

2.

Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs.

Hewitt SL, Bai A, Bailey D, Ichikawa K, Zielinski J, Karp R, Apte A, Arnold K, Zacharek SJ, Iliou MS, Bhatt K, Garnaas M, Musenge F, Davis A, Khatwani N, Su SV, MacLean G, Farlow SJ, Burke K, Frederick JP.

Sci Transl Med. 2019 Jan 30;11(477). pii: eaat9143. doi: 10.1126/scitranslmed.aat9143.

PMID:
30700577
3.

Phragmoplast microtubule dynamics - a game of zones.

Smertenko A, Hewitt SL, Jacques CN, Kacprzyk R, Liu Y, Marcec MJ, Moyo L, Ogden A, Oung HM, Schmidt S, Serrano-Romero EA.

J Cell Sci. 2018 Jan 29;131(2). pii: jcs203331. doi: 10.1242/jcs.203331. Review.

4.

The Conserved ATM Kinase RAG2-S365 Phosphorylation Site Limits Cleavage Events in Individual Cells Independent of Any Repair Defect.

Hewitt SL, Wong JB, Lee JH, Nishana M, Chen H, Coussens M, Arnal SM, Blumenberg LM, Roth DB, Paull TT, Skok JA.

Cell Rep. 2017 Oct 24;21(4):979-993. doi: 10.1016/j.celrep.2017.09.084.

5.

VH replacement in primary immunoglobulin repertoire diversification.

Sun A, Novobrantseva TI, Coffre M, Hewitt SL, Jensen K, Skok JA, Rajewsky K, Koralov SB.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E458-66. doi: 10.1073/pnas.1418001112. Epub 2015 Jan 21.

6.

Close proximity to Igh is a contributing factor to AID-mediated translocations.

Rocha PP, Micsinai M, Kim JR, Hewitt SL, Souza PP, Trimarchi T, Strino F, Parisi F, Kluger Y, Skok JA.

Mol Cell. 2012 Sep 28;47(6):873-85. doi: 10.1016/j.molcel.2012.06.036. Epub 2012 Aug 2.

7.

A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location.

Xiang Y, Zhou X, Hewitt SL, Skok JA, Garrard WT.

J Immunol. 2011 May 1;186(9):5356-66. doi: 10.4049/jimmunol.1003794. Epub 2011 Mar 25.

8.

RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation.

Collins A, Hewitt SL, Chaumeil J, Sellars M, Micsinai M, Allinne J, Parisi F, Nora EP, Bolland DJ, Corcoran AE, Kluger Y, Bosselut R, Ellmeier W, Chong MM, Littman DR, Skok JA.

Immunity. 2011 Mar 25;34(3):303-14. doi: 10.1016/j.immuni.2011.03.004.

9.

It takes two: communication between homologous alleles preserves genomic stability during V(D)J recombination.

Brandt VL, Hewitt SL, Skok JA.

Nucleus. 2010 Jan-Feb;1(1):23-9. doi: 10.4161/nucl.1.1.10595.

10.

Chromosome dynamics and the regulation of V(D)J recombination.

Hewitt SL, Chaumeil J, Skok JA.

Immunol Rev. 2010 Sep;237(1):43-54. doi: 10.1111/j.1600-065X.2010.00931.x. Review.

PMID:
20727028
11.

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci.

Hewitt SL, Yin B, Ji Y, Chaumeil J, Marszalek K, Tenthorey J, Salvagiotto G, Steinel N, Ramsey LB, Ghysdael J, Farrar MA, Sleckman BP, Schatz DG, Busslinger M, Bassing CH, Skok JA.

Nat Immunol. 2009 Jun;10(6):655-64. doi: 10.1038/ni.1735. Erratum in: Nat Immunol. 2009 Jun;10(6). doi: 10.1038/ni.1735. Nat Immunol. 2009 Sep;10(9):1034. Nat Immunol. 2010 Mar;11(4):355-6.

12.

Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells.

Hewitt SL, Farmer D, Marszalek K, Cadera E, Liang HE, Xu Y, Schlissel MS, Skok JA.

Nat Immunol. 2008 Apr;9(4):396-404. doi: 10.1038/ni1567. Epub 2008 Feb 24.

13.

Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation.

Hewitt SL, High FA, Reiner SL, Fisher AG, Merkenschlager M.

Eur J Immunol. 2004 Dec;34(12):3604-13.

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