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Items: 1 to 50 of 696

1.

Evidence for pre-climacteric activation of AOX transcription during cold-induced conditioning to ripen in European pear (Pyrus communis L.).

Hendrickson C, Hewitt S, Swanson ME, Einhorn T, Dhingra A.

PLoS One. 2019 Dec 4;14(12):e0225886. doi: 10.1371/journal.pone.0225886. eCollection 2019.

2.

CDK7 is a reliable prognostic factor and novel therapeutic target in epithelial ovarian cancer.

Kim J, Cho YJ, Ryu JY, Hwang I, Han HD, Ahn HJ, Kim WY, Cho H, Chung JY, Hewitt SM, Kim JH, Kim BG, Bae DS, Choi CH, Lee JW.

Gynecol Oncol. 2019 Nov 24. pii: S0090-8258(19)31625-7. doi: 10.1016/j.ygyno.2019.11.004. [Epub ahead of print]

PMID:
31776040
3.

A functionalized hydroxydopamine quinone links thiol modification to neuronal cell death.

Farzam A, Chohan K, Strmiskova M, Hewitt SJ, Park DS, Pezacki JP, Özcelik D.

Redox Biol. 2019 Nov 9;28:101377. doi: 10.1016/j.redox.2019.101377. [Epub ahead of print]

4.

Application of convolutional neural networks to breast biopsies to delineate tissue correlates of mammographic breast density.

Mullooly M, Ehteshami Bejnordi B, Pfeiffer RM, Fan S, Palakal M, Hada M, Vacek PM, Weaver DL, Shepherd JA, Fan B, Mahmoudzadeh AP, Wang J, Malkov S, Johnson JM, Herschorn SD, Sprague BL, Hewitt S, Brinton LA, Karssemeijer N, van der Laak J, Beck A, Sherman ME, Gierach GL.

NPJ Breast Cancer. 2019 Nov 19;5:43. doi: 10.1038/s41523-019-0134-6. eCollection 2019.

5.

Associations of tobacco smoking with body mass distribution; a population-based study of 65,875 men and women in midlife.

Graff-Iversen S, Hewitt S, Forsén L, Grøtvedt L, Ariansen I.

BMC Public Health. 2019 Nov 1;19(1):1439. doi: 10.1186/s12889-019-7807-9.

6.

Using Digital Pathology to Understand Epithelial Characteristics of Benign Breast Disease among Women Undergoing Diagnostic Image-Guided Breast Biopsy.

Mullooly M, Puvanesarajah S, Fan S, Pfeiffer RM, Olsson LT, Hada M, Kirk EL, Vacek PM, Weaver DL, Shepherd J, Mahmoudzadeh A, Wang J, Malkov S, Johnson JM, Hewitt SM, Herschorn SD, Sherman ME, Troester MA, Gierach GL.

Cancer Prev Res (Phila). 2019 Dec;12(12):861-870. doi: 10.1158/1940-6207.CAPR-19-0120. Epub 2019 Oct 23.

PMID:
31645342
7.

Efficacy and tolerability of anti-programmed death-ligand 1 (PD-L1) antibody (Avelumab) treatment in advanced thymoma.

Rajan A, Heery CR, Thomas A, Mammen AL, Perry S, O'Sullivan Coyne G, Guha U, Berman A, Szabo E, Madan RA, Ballester LY, Pittaluga S, Donahue RN, Tsai YT, Lepone LM, Chin K, Ginty F, Sood A, Hewitt SM, Schlom J, Hassan R, Gulley JL.

J Immunother Cancer. 2019 Oct 21;7(1):269. doi: 10.1186/s40425-019-0723-9.

8.

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.

Wong JB, Hewitt SL, Heltemes-Harris LM, Mandal M, Johnson K, Rajewsky K, Koralov SB, Clark MR, Farrar MA, Skok JA.

Nat Commun. 2019 Oct 18;10(1):4768. doi: 10.1038/s41467-019-12824-z.

9.

ALDH1A2 Is a Candidate Tumor Suppressor Gene in Ovarian Cancer.

Choi JA, Kwon H, Cho H, Chung JY, Hewitt SM, Kim JH.

Cancers (Basel). 2019 Oct 14;11(10). pii: E1553. doi: 10.3390/cancers11101553.

10.

Fatal encephalopathy with wild-type JC virus and ruxolitinib therapy.

Reoma LB, Trindade CJ, Monaco MC, Solis J, Montojo MG, Vu P, Johnson K, Beck E, Nair G, Khan OI, Quezado M, Hewitt SM, Reich DS, Childs R, Nath A.

Ann Neurol. 2019 Dec;86(6):878-884. doi: 10.1002/ana.25608. Epub 2019 Oct 16.

PMID:
31600832
11.

Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer.

Ma L, Hernandez MO, Zhao Y, Mehta M, Tran B, Kelly M, Rae Z, Hernandez JM, Davis JL, Martin SP, Kleiner DE, Hewitt SM, Ylaya K, Wood BJ, Greten TF, Wang XW.

Cancer Cell. 2019 Oct 14;36(4):418-430.e6. doi: 10.1016/j.ccell.2019.08.007. Epub 2019 Oct 3.

12.

No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication.

Bozzi G, Simonetti FR, Watters SA, Anderson EM, Gouzoulis M, Kearney MF, Rote P, Lange C, Shao W, Gorelick R, Fullmer B, Kumar S, Wank S, Hewitt S, Kleiner DE, Hattori J, Bale MJ, Hill S, Bell J, Rehm C, Grossman Z, Yarchoan R, Uldrick T, Maldarelli F.

Sci Adv. 2019 Sep 25;5(9):eaav2045. doi: 10.1126/sciadv.aav2045. eCollection 2019 Sep.

13.

Enlightening kidney pathophysiology.

Hewitt SM, Star RA.

Nat Mater. 2019 Oct;18(10):1034-1035. doi: 10.1038/s41563-019-0490-5. No abstract available.

PMID:
31537941
14.

Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein.

Byun JS, Park S, Yi DI, Shin JH, Hernandez SG, Hewitt SM, Nicklaus MC, Peach ML, Guasch L, Tang B, Wakefield LM, Yan T, Caban A, Jones A, Kabbout M, Vohra N, Nápoles AM, Singhal S, Yancey R, De Siervi A, Gardner K.

Cell Death Dis. 2019 Sep 18;10(10):689. doi: 10.1038/s41419-019-1892-7.

15.

Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer.

Shin S, Kim K, Kim HR, Ylaya K, Do SI, Hewitt SM, Park HS, Roe JS, Chung JY, Song J.

Cell Death Differ. 2019 Sep 17. doi: 10.1038/s41418-019-0419-1. [Epub ahead of print]

PMID:
31527799
16.

A dataset describing a suite of novel antibody reagents for the RAS signaling network.

Schoenherr RM, Huang D, Voytovich UJ, Ivey RG, Kennedy JJ, Saul RG, Colantonio S, Roberts RR, Knotts JG, Kaczmarczyk JA, Perry C, Hewitt SM, Bocik W, Whiteley GR, Hiltke T, Boja ES, Rodriguez H, Whiteaker JR, Paulovich AG.

Sci Data. 2019 Aug 29;6(1):160. doi: 10.1038/s41597-019-0166-7.

17.

Renal Fibrosis: Common Enemy of Many Origins.

Hewitt SM, Schaefer L.

J Histochem Cytochem. 2019 Sep;67(9):621. doi: 10.1369/0022155419865531. No abstract available.

PMID:
31451045
18.

T-Cell Receptor Gene Therapy for Human Papillomavirus-Associated Epithelial Cancers: A First-in-Human, Phase I/II Study.

Doran SL, Stevanović S, Adhikary S, Gartner JJ, Jia L, Kwong MLM, Faquin WC, Hewitt SM, Sherry RM, Yang JC, Rosenberg SA, Hinrichs CS.

J Clin Oncol. 2019 Oct 20;37(30):2759-2768. doi: 10.1200/JCO.18.02424. Epub 2019 Aug 13.

19.

A Pilot Study of Sirolimus in Subjects with Cowden Syndrome or Other Syndromes Characterized by Germline Mutations in PTEN.

Komiya T, Blumenthal GM, DeChowdhury R, Fioravanti S, Ballas MS, Morris J, Hornyak TJ, Wank S, Hewitt SM, Morrow B, Memmott RM, Rajan A, Dennis PA.

Oncologist. 2019 Jul 26. pii: theoncologist.2019-0514. doi: 10.1634/theoncologist.2019-0514. [Epub ahead of print]

PMID:
31350329
20.

Bone metabolism, bone mineral density and low-energy fractures 10 years after Roux-en-Y gastric bypass.

Blom-Høgestøl IK, Hewitt S, Chahal-Kummen M, Brunborg C, Gulseth HL, Kristinsson JA, Eriksen EF, Mala T.

Bone. 2019 Oct;127:436-445. doi: 10.1016/j.bone.2019.07.014. Epub 2019 Jul 16.

PMID:
31323430
21.

Agreement in Histological Assessment of Mitotic Activity Between Microscopy and Digital Whole Slide Images Informs Conversion for Clinical Diagnosis.

Wei BR, Halsey CH, Hoover SB, Puri M, Yang HH, Gallas BD, Lee MP, Chen W, Durham AC, Dwyer JE, Sánchez MD, Traslavina RP, Frank C, Bradley C, McGill LD, Esplin DG, Schaffer PA, Cramer SD, Lyle LT, Beck J, Buza E, Gong Q, Hewitt SM, Simpson RM.

Acad Pathol. 2019 Jul 11;6:2374289519859841. doi: 10.1177/2374289519859841. eCollection 2019 Jan-Dec.

22.

Forkhead box protein O1 (FOXO1) and paired box gene 3 (PAX3) overexpression is associated with poor prognosis in patients with cervical cancer.

Chay DB, Han GH, Nam S, Cho H, Chung JY, Hewitt SM.

Int J Clin Oncol. 2019 Nov;24(11):1429-1439. doi: 10.1007/s10147-019-01507-w. Epub 2019 Jul 13.

PMID:
31302815
23.

Cas9-based enrichment and single-molecule sequencing for precise characterization of genomic duplications.

Watson CM, Crinnion LA, Hewitt S, Bates J, Robinson R, Carr IM, Sheridan E, Adlard J, Bonthron DT.

Lab Invest. 2019 Jul 4. doi: 10.1038/s41374-019-0283-0. [Epub ahead of print]

PMID:
31273287
24.

A mouse model of Proteus syndrome.

Lindhurst MJ, Brinster LR, Kondolf HC, Shwetar JJ, Yourick MR, Shiferaw H, Keppler-Noreuil KM, Elliot G, Rivas C, Garrett L, Gomez-Rodriguez J, Sebire NJ, Hewitt SM, Schwartzberg PL, Biesecker LG.

Hum Mol Genet. 2019 Sep 1;28(17):2920-2936. doi: 10.1093/hmg/ddz116.

PMID:
31194862
25.

A simple, robust, universal assay for real-time enzyme monitoring by signalling changes in nucleoside phosphate anion concentration using a europium(iii)-based anion receptor.

Hewitt SH, Ali R, Mailhot R, Antonen CR, Dodson CA, Butler SJ.

Chem Sci. 2019 May 1;10(20):5373-5381. doi: 10.1039/c9sc01552c. eCollection 2019 May 28.

26.

Decoding the Inversion Symmetry Underlying Transcription Factor DNA-Binding Specificity and Functionality in the Genome.

Coons LA, Burkholder AB, Hewitt SC, McDonnell DP, Korach KS.

iScience. 2019 May 31;15:552-591. doi: 10.1016/j.isci.2019.04.006. Epub 2019 Apr 6.

27.

A distal super enhancer mediates estrogen-dependent mouse uterine-specific gene transcription of Igf1 (insulin-like growth factor 1).

Hewitt SC, Lierz SL, Garcia M, Hamilton KJ, Gruzdev A, Grimm SA, Lydon JP, Demayo FJ, Korach KS.

J Biol Chem. 2019 Jun 21;294(25):9746-9759. doi: 10.1074/jbc.RA119.008759. Epub 2019 May 9.

PMID:
31073032
28.

Durvalumab in Combination with Olaparib in Patients with Relapsed SCLC: Results from a Phase II Study.

Thomas A, Vilimas R, Trindade C, Erwin-Cohen R, Roper N, Xi L, Krishnasamy V, Levy E, Mammen A, Nichols S, Chen Y, Velcheti V, Yin F, Szabo E, Pommier Y, Steinberg SM, Trepel JB, Raffeld M, Young HA, Khan J, Hewitt S, Lee JM.

J Thorac Oncol. 2019 Aug;14(8):1447-1457. doi: 10.1016/j.jtho.2019.04.026. Epub 2019 May 4.

PMID:
31063862
29.

Hepatitis B Surface Antigen Activates Unfolded Protein Response in Forming Ground Glass Hepatocytes of Chronic Hepatitis B.

Li Y, Xia Y, Cheng X, Kleiner DE, Hewitt SM, Sproch J, Li T, Zhuang H, Liang TJ.

Viruses. 2019 Apr 25;11(4). pii: E386. doi: 10.3390/v11040386.

30.

Automated Computational Detection, Quantitation, and Mapping of Mitosis in Whole-Slide Images for Clinically Actionable Surgical Pathology Decision Support.

Puri M, Hoover SB, Hewitt SM, Wei BR, Adissu HA, Halsey CHC, Beck J, Bradley C, Cramer SD, Durham AC, Esplin DG, Frank C, Lyle LT, McGill LD, Sánchez MD, Schaffer PA, Traslavina RP, Buza E, Yang HH, Lee MP, Dwyer JE, Simpson RM.

J Pathol Inform. 2019 Feb 7;10:4. doi: 10.4103/jpi.jpi_59_18. eCollection 2019.

31.

Data, Information, and Knowledge.

Hewitt SM.

J Histochem Cytochem. 2019 Apr;67(4):227-228. doi: 10.1369/0022155419836995. No abstract available.

PMID:
30909851
32.

Understanding the measurement properties of the incremental shuttle walk test in patients with severe asthma.

Majd S, Hewitt SM, Apps LD, Murphy AC, Bradding P, Singh SJ, Green RH, Evans RA.

Respirology. 2019 Aug;24(8):752-757. doi: 10.1111/resp.13519. Epub 2019 Mar 18.

PMID:
30887627
33.

An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers.

Lee TK, Murthy SR, Cawley NX, Dhanvantari S, Hewitt SM, Lou H, Lau T, Ma S, Huynh T, Wesley RA, Ng IO, Pacak K, Poon RT, Loh YP.

J Clin Invest. 2019 Mar 18;130:1804. doi: 10.1172/JCI128836. eCollection 2019 Mar 18. No abstract available.

34.

Combination immunotherapy with IL-4 Pseudomonas exotoxin and IFN-α and IFN-γ mediate antitumor effects in vitro and in a mouse model of human ovarian cancer.

Green DS, Husain SR, Johnson CL, Sato Y, Han J, Joshi B, Hewitt SM, Puri RK, Zoon KC.

Immunotherapy. 2019 Apr;11(6):483-496. doi: 10.2217/imt-2018-0158.

PMID:
30860437
35.

APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors.

Roper N, Gao S, Maity TK, Banday AR, Zhang X, Venugopalan A, Cultraro CM, Patidar R, Sindiri S, Brown AL, Goncearenco A, Panchenko AR, Biswas R, Thomas A, Rajan A, Carter CA, Kleiner DE, Hewitt SM, Khan J, Prokunina-Olsson L, Guha U.

Cell Rep. 2019 Mar 5;26(10):2651-2666.e6. doi: 10.1016/j.celrep.2019.02.028.

36.

Associations of CDH1 germline variant location and cancer phenotype in families with hereditary diffuse gastric cancer (HDGC).

Lo W, Zhu B, Sabesan A, Wu HH, Powers A, Sorber RA, Ravichandran S, Chen I, McDuffie LA, Quadri HS, Beane JD, Calzone K, Miettinen MM, Hewitt SM, Koh C, Heller T, Wacholder S, Rudloff U.

J Med Genet. 2019 Jun;56(6):370-379. doi: 10.1136/jmedgenet-2018-105361. Epub 2019 Feb 11.

37.

Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells.

Simon N, Antignani A, Hewitt SM, Gadina M, Alewine C, FitzGerald D.

JCI Insight. 2019 Mar 7;4(5). pii: 123281. doi: 10.1172/jci.insight.123281. eCollection 2019 Mar 7.

38.

An alternative to array-based diagnostics: a prospectively recruited cohort, comparing arrayCGH to next-generation sequencing to evaluate foetal structural abnormalities.

Walker L, Watson CM, Hewitt S, Crinnion LA, Bonthron DT, Cohen KE.

J Obstet Gynaecol. 2019 Apr;39(3):328-334. doi: 10.1080/01443615.2018.1522529. Epub 2019 Feb 3.

PMID:
30714504
39.

Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs.

Hewitt SL, Bai A, Bailey D, Ichikawa K, Zielinski J, Karp R, Apte A, Arnold K, Zacharek SJ, Iliou MS, Bhatt K, Garnaas M, Musenge F, Davis A, Khatwani N, Su SV, MacLean G, Farlow SJ, Burke K, Frederick JP.

Sci Transl Med. 2019 Jan 30;11(477). pii: eaat9143. doi: 10.1126/scitranslmed.aat9143.

PMID:
30700577
40.

Immunophenotypic Characterization of Canine Splenic Follicular-Derived B-Cell Lymphoma.

Stein L, Bacmeister C, Ylaya K, Fetsch P, Wang Z, Hewitt SM, Kiupel M.

Vet Pathol. 2019 May;56(3):350-357. doi: 10.1177/0300985818823668. Epub 2019 Jan 13.

PMID:
30636524
41.

Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma.

Sun W, Chatterjee B, Shern JF, Patidar R, Song Y, Wang Y, Walker RL, Pawel BR, Linardic CM, Houghton P, Hewitt SM, Edelman DC, Khan J, Meltzer PS, Barr FG.

Int J Cancer. 2019 Jun 1;144(11):2707-2717. doi: 10.1002/ijc.32006. Epub 2019 Jan 15.

PMID:
30565669
42.

Correction: Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF.

Han SY, Ko A, Kitano H, Choi CH, Lee MS, Seo J, Fukuoka J, Kim SY, Hewitt SM, Chung JY, Song J.

Cancer Res. 2018 Dec 15;78(24):6903. doi: 10.1158/0008-5472.CAN-18-3311. No abstract available.

PMID:
30552121
43.

Let's 'cut to the chase' on malaria elimination in the Greater Mekong Subregion.

Hewitt SE.

Trans R Soc Trop Med Hyg. 2019 Apr 1;113(4):161-162. doi: 10.1093/trstmh/try125.

PMID:
30551174
44.

Building a Digital Wind Farm.

Hewitt S, Margetts L, Revell A.

Arch Comput Methods Eng. 2018;25(4):879-899. doi: 10.1007/s11831-017-9222-7. Epub 2017 Apr 18.

45.

APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R.

Okamoto K, Rausch JW, Wakashin H, Fu Y, Chung JY, Dummer PD, Shin MK, Chandra P, Suzuki K, Shrivastav S, Rosenberg AZ, Hewitt SM, Ray PE, Noiri E, Le Grice SFJ, Hoek M, Han Z, Winkler CA, Kopp JB.

Commun Biol. 2018 Nov 7;1:188. doi: 10.1038/s42003-018-0188-2. eCollection 2018.

46.

Genomic Network-Based Analysis Reveals Pancreatic Adenocarcinoma Up-Regulating Factor-Related Prognostic Markers in Cervical Carcinoma.

Kim J, Chung JY, Kim TJ, Lee JW, Kim BG, Bae DS, Choi CH, Hewitt SM.

Front Oncol. 2018 Oct 23;8:465. doi: 10.3389/fonc.2018.00465. eCollection 2018.

47.

Microvascular inflammation in renal allograft biopsies assessed by endothelial and leukocyte co-immunostain: a retrospective study on reproducibility and clinical/prognostic correlates.

Delsante M, Maggiore U, Levi J, Kleiner DE, Jackson AM, Arend LJ, Hewitt SM, Carter-Monroe N, Bagnasco SM, Rosenberg AZ.

Transpl Int. 2019 Mar;32(3):300-312. doi: 10.1111/tri.13371. Epub 2018 Dec 11.

PMID:
30395360
48.

Patients with learning disabilities should be considered at high risk of cervical spine injury.

Byrne C, Johnson GD, Tabner AJ, Hewitt SM.

Emerg Med J. 2019 Jan;36(1):54. doi: 10.1136/emermed-2018-208117. Epub 2018 Oct 20. No abstract available.

PMID:
30343267
49.

Negative elongation factor is essential for endometrial function.

Hewitt SC, Li R, Adams N, Winuthayanon W, Hamilton KJ, Donoghue LJ, Lierz SL, Garcia M, Lydon JP, DeMayo FJ, Adelman K, Korach KS.

FASEB J. 2019 Feb;33(2):3010-3023. doi: 10.1096/fj.201801752. Epub 2018 Oct 17.

PMID:
30332301
50.

Identification of water use efficiency related genes in 'Garnem' almond-peach rootstock using time-course transcriptome analysis.

Bielsa B, Hewitt S, Reyes-Chin-Wo S, Dhingra A, Rubio-Cabetas MJ.

PLoS One. 2018 Oct 11;13(10):e0205493. doi: 10.1371/journal.pone.0205493. eCollection 2018.

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