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Items: 28


Glucocorticoid induced adrenal insufficiency is common in steroid treated glomerular diseases - proposed strategy for screening and management.

Karangizi AHK, Al-Shaghana M, Logan S, Criseno S, Webster R, Boelaert K, Hewins P, Harper L.

BMC Nephrol. 2019 May 6;20(1):154. doi: 10.1186/s12882-019-1354-6.


Adult minimal-change disease: observational data from a UK centre on patient characteristics, therapies, and outcomes.

Fenton A, Smith SW, Hewins P.

BMC Nephrol. 2018 Aug 16;19(1):207. doi: 10.1186/s12882-018-0999-x.


Tubulointerstitial nephritis and uveitis (TINU) syndrome: a systematic review of its epidemiology, demographics and risk factors.

Okafor LO, Hewins P, Murray PI, Denniston AK.

Orphanet J Rare Dis. 2017 Jul 14;12(1):128. doi: 10.1186/s13023-017-0677-2. Review.


The efficacy of rituximab in adult frequently relapsing minimal change disease.

King C, Logan S, Smith SW, Hewins P.

Clin Kidney J. 2017 Feb;10(1):16-19. doi: 10.1093/ckj/sfw100. Epub 2016 Oct 24.


Use of genome sequencing to identify hepatitis C virus transmission in a renal healthcare setting.

Garvey MI, Bradley CW, Holden KL, Hewins P, Ngui SL, Tedder R, Jumaa P, Smit E.

J Hosp Infect. 2017 Jun;96(2):157-162. doi: 10.1016/j.jhin.2017.01.002. Epub 2017 Jan 16.


Autoimmunity to the alpha 3 chain of type IV collagen in glomerulonephritis is triggered by 'autoantigen complementarity'.

Reynolds J, Preston GA, Pressler BM, Hewins P, Brown M, Roth A, Alderman E, Bunch D, Jennette JC, Cook HT, Falk RJ, Pusey CD.

J Autoimmun. 2015 May;59:8-18. doi: 10.1016/j.jaut.2015.01.003. Epub 2015 Apr 2.


Chronic Q fever: An ongoing challenge in diagnosis and management.

Das I, Guest N, Steeds R, Hewins P.

Can J Infect Dis Med Microbiol. 2014 Spring;25(1):35-7.


Caveolin-1 single nucleotide polymorphism in antineutrophil cytoplasmic antibody associated vasculitis.

Chand S, Holle JU, Hilhorst M, Simmonds MJ, Smith S, Kamesh L, Hewins P, McKnight AJ, Maxwell AP, Cohen Tervaert JW, Wieczorek S, Harper L, Borrows R.

PLoS One. 2013 Jul 19;8(7):e69022. doi: 10.1371/journal.pone.0069022. Print 2013.


Anti-plasminogen antibodies compromise fibrinolysis and associate with renal histology in ANCA-associated vasculitis.

Berden AE, Nolan SL, Morris HL, Bertina RM, Erasmus DD, Hagen EC, Hayes DP, van Tilburg NH, Bruijn JA, Savage CO, Bajema IM, Hewins P.

J Am Soc Nephrol. 2010 Dec;21(12):2169-79. doi: 10.1681/ASN.2010030274. Epub 2010 Sep 16.


Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis.

Ciavatta DJ, Yang J, Preston GA, Badhwar AK, Xiao H, Hewins P, Nester CM, Pendergraft WF 3rd, Magnuson TR, Jennette JC, Falk RJ.

J Clin Invest. 2010 Sep;120(9):3209-19. doi: 10.1172/JCI40034. Epub 2010 Aug 16.


Longitudinal studies of patients with ANCA vasculitis demonstrate concurrent reactivity to complementary PR3 protein segments cPR3m and cPR3C and with no reactivity to cPR3N.

Hewins P, Belmonte F, Charles Jennette J, Falk RJ, Preston GA.

Autoimmunity. 2011 Mar;44(2):98-106. doi: 10.3109/08916934.2010.491843. Epub 2010 Aug 16.


Prediction of ESRD in pauci-immune necrotizing glomerulonephritis: quantitative histomorphometric assessment and serum creatinine.

Day CJ, Howie AJ, Nightingale P, Shabir S, Adu D, Savage CO, Hewins P.

Am J Kidney Dis. 2010 Feb;55(2):250-8. doi: 10.1053/j.ajkd.2009.10.047. Epub 2009 Dec 31.


Quantitative assessment of serum and urinary polyclonal free light chains in patients with chronic kidney disease.

Hutchison CA, Harding S, Hewins P, Mead GP, Townsend J, Bradwell AR, Cockwell P.

Clin J Am Soc Nephrol. 2008 Nov;3(6):1684-90. doi: 10.2215/CJN.02290508.


Antibodies with dual reactivity to plasminogen and complementary PR3 in PR3-ANCA vasculitis.

Bautz DJ, Preston GA, Lionaki S, Hewins P, Wolberg AS, Yang JJ, Hogan SL, Chin H, Moll S, Jennette JC, Falk RJ.

J Am Soc Nephrol. 2008 Dec;19(12):2421-9. doi: 10.1681/ASN.2008030270. Epub 2008 Aug 13.


The role of renal biopsy in women with kidney disease identified in pregnancy.

Day C, Hewins P, Hildebrand S, Sheikh L, Taylor G, Kilby M, Lipkin G.

Nephrol Dial Transplant. 2008 Jan;23(1):201-6. Epub 2007 Aug 25.


Recurrences and infections during continuous immunosuppressive therapy after beginning dialysis in ANCA-associated vasculitis.

Weidanz F, Day CJ, Hewins P, Savage CO, Harper L.

Am J Kidney Dis. 2007 Jul;50(1):36-46.


Cholestasis in pregnancy associated with ciclosporin therapy in renal transplant recipients.

Day C, Hewins P, Sheikh L, Kilby M, McPake D, Lipkin G.

Transpl Int. 2006 Dec;19(12):1026-9.


IL-18 is upregulated in the kidney and primes neutrophil responsiveness in ANCA-associated vasculitis.

Hewins P, Morgan MD, Holden N, Neil D, Williams JM, Savage CO, Harper L.

Kidney Int. 2006 Feb;69(3):605-15.


ANCA-induced neutrophil F-actin polymerization: implications for microvascular inflammation.

Tse WY, Nash GB, Hewins P, Savage CO, Adu D.

Kidney Int. 2005 Jan;67(1):130-9.


The influence of autoantibodies to myeloperoxidase on neutrophil function and intracellular signaling.

Williams J, Hewins P, Savage C.

Jpn J Infect Dis. 2004 Oct;57(5):S5-6. Review.


Anti-neutrophil cytoplasm antibody IgG subclasses in Wegener's granulomatosis: a possible pathogenic role for the IgG4 subclass.

Holland M, Hewins P, Goodall M, Adu D, Jefferis R, Savage CO.

Clin Exp Immunol. 2004 Oct;138(1):183-92.


Activation of Syk in neutrophils by antineutrophil cytoplasm antibodies occurs via Fcgamma receptors and CD18.

Hewins P, Williams JM, Wakelam MJ, Savage CO.

J Am Soc Nephrol. 2004 Mar;15(3):796-808.


New developments in the pathogenesis of ANCA-associated vasculitis.

Day CJ, Hewins P, Savage CO.

Clin Exp Rheumatol. 2003 Nov-Dec;21(6 Suppl 32):S35-48. Review.


ANCA and neutrophil biology.

Hewins P, Savage CO.

Kidney Blood Press Res. 2003;26(4):221-5. Review. No abstract available.


Anti-neutrophil cytoplasm antibody associated vasculitis.

Hewins P, Savage C.

Int J Biochem Cell Biol. 2003 Mar;35(3):277-82. Review.


Antineutrophil cytoplasmic antibodies stabilize adhesion and promote migration of flowing neutrophils on endothelial cells.

Radford DJ, Luu NT, Hewins P, Nash GB, Savage CO.

Arthritis Rheum. 2001 Dec;44(12):2851-61.


Is Wegener's granulomatosis an autoimmune disease?

Hewins P, Tervaert JW, Savage CO, Kallenberg CG.

Curr Opin Rheumatol. 2000 Jan;12(1):3-10. Review.


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