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Items: 1 to 50 of 53

1.

Bio-Guided Fractionation of Papaya Leaf Juice for Delineating the Components Responsible for the Selective Anti-proliferative Effects on Prostate Cancer Cells.

Pandey S, Walpole C, Shaw PN, Cabot PJ, Hewavitharana AK, Batra J.

Front Pharmacol. 2018 Nov 16;9:1319. doi: 10.3389/fphar.2018.01319. eCollection 2018.

2.

Separation of highly charged compounds using competing ions with hydrophilic interaction liquid chromatography - Application to assay of cellular nucleotides.

Hewavitharana AK, Narayan V, Duley JA.

J Chromatogr A. 2018 Sep 14;1567:233-238. doi: 10.1016/j.chroma.2018.07.006. Epub 2018 Jul 3.

PMID:
29983167
4.

Simultaneous determination of 12 vitamin D compounds in human serum using online sample preparation and liquid chromatography-tandem mass spectrometry.

Abu Kassim NS, Shaw PN, Hewavitharana AK.

J Chromatogr A. 2018 Jan 19;1533:57-65. doi: 10.1016/j.chroma.2017.12.012. Epub 2017 Dec 6.

PMID:
29229333
5.

Selective anti-proliferative activities of Carica papaya leaf juice extracts against prostate cancer.

Pandey S, Walpole C, Cabot PJ, Shaw PN, Batra J, Hewavitharana AK.

Biomed Pharmacother. 2017 May;89:515-523. doi: 10.1016/j.biopha.2017.02.050. Epub 2017 Feb 27.

PMID:
28249253
6.

Production of N-acyl homoserine lactones by the sponge-associated marine actinobacteria Salinispora arenicola and Salinispora pacifica.

Bose U, Ortori CA, Sarmad S, Barrett DA, Hewavitharana AK, Hodson MP, Fuerst JA, Shaw PN, Boden R.

FEMS Microbiol Lett. 2017 Jan 1;364(2). doi: 10.1093/femsle/fnx002.

PMID:
28087611
7.

The efficacy of Dynorphin fragments at the κ, μ and δ opioid receptor in transfected HEK cells and in an animal model of unilateral peripheral inflammation.

Morgan M, Heffernan A, Benhabib F, Wagner S, Hewavitharana AK, Shaw PN, Cabot PJ.

Peptides. 2017 Mar;89:9-16. doi: 10.1016/j.peptides.2016.12.019. Epub 2016 Dec 31.

PMID:
28049031
8.

Anti-inflammatory and immunomodulatory properties of Carica papaya.

Pandey S, Cabot PJ, Shaw PN, Hewavitharana AK.

J Immunotoxicol. 2016 Jul;13(4):590-602. doi: 10.3109/1547691X.2016.1149528. Epub 2016 Jul 14. Review.

PMID:
27416522
9.

The effect of pasteurization on trace elements in donor breast milk.

Mohd-Taufek N, Cartwright D, Davies M, Hewavitharana AK, Koorts P, McConachy H, Shaw PN, Sumner R, Whitfield K.

J Perinatol. 2016 Oct;36(10):897-900. doi: 10.1038/jp.2016.88. Epub 2016 Jun 2.

PMID:
27253894
10.

Simultaneous quantitative analysis of nine vitamin D compounds in human blood using LC-MS/MS.

Abu Kassim NS, Gomes FP, Shaw PN, Hewavitharana AK.

Bioanalysis. 2016;8(5):397-411. doi: 10.4155/bio.15.260. Epub 2016 Feb 19.

PMID:
26893268
11.

Traditional Aboriginal Preparation Alters the Chemical Profile of Carica papaya Leaves and Impacts on Cytotoxicity towards Human Squamous Cell Carcinoma.

Nguyen TT, Parat MO, Shaw PN, Hewavitharana AK, Hodson MP.

PLoS One. 2016 Feb 1;11(2):e0147956. doi: 10.1371/journal.pone.0147956. eCollection 2016.

12.

Effect of pasteurisation on the concentrations of vitamin D compounds in donor breastmilk.

Gomes FP, Shaw PN, Whitfield K, Koorts P, McConachy H, Hewavitharana AK.

Int J Food Sci Nutr. 2016;67(1):16-9. doi: 10.3109/09637486.2015.1126566.

PMID:
26796072
13.

Chemical Characterization and in Vitro Cytotoxicity on Squamous Cell Carcinoma Cells of Carica papaya Leaf Extracts.

Nguyen TT, Parat MO, Hodson MP, Pan J, Shaw PN, Hewavitharana AK.

Toxins (Basel). 2015 Dec 24;8(1). pii: E7. doi: 10.3390/toxins8010007.

14.

Determination of four sulfated vitamin D compounds in human biological fluids by liquid chromatography-tandem mass spectrometry.

Gomes FP, Shaw PN, Hewavitharana AK.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jan 15;1009-1010:80-6. doi: 10.1016/j.jchromb.2015.12.014. Epub 2015 Dec 9.

PMID:
26708628
15.

Simultaneous quantitative analysis of eight vitamin D analogues in milk using liquid chromatography-tandem mass spectrometry.

Gomes FP, Shaw PN, Whitfield K, Hewavitharana AK.

Anal Chim Acta. 2015 Sep 3;891:211-20. doi: 10.1016/j.aca.2015.08.017. Epub 2015 Aug 22.

PMID:
26388380
16.

Breastmilk-Saliva Interactions Boost Innate Immunity by Regulating the Oral Microbiome in Early Infancy.

Al-Shehri SS, Knox CL, Liley HG, Cowley DM, Wright JR, Henman MG, Hewavitharana AK, Charles BG, Shaw PN, Sweeney EL, Duley JA.

PLoS One. 2015 Sep 1;10(9):e0135047. doi: 10.1371/journal.pone.0135047. eCollection 2015.

17.

LC-MS-based metabolomics study of marine bacterial secondary metabolite and antibiotic production in Salinispora arenicola.

Bose U, Hewavitharana AK, Ng YK, Shaw PN, Fuerst JA, Hodson MP.

Mar Drugs. 2015 Jan 7;13(1):249-66. doi: 10.3390/md13010249.

18.

Review of procedures used for the extraction of anti-cancer compounds from tropical plants.

Pandey S, Shaw PN, Hewavitharana AK.

Anticancer Agents Med Chem. 2015;15(3):314-26. Review.

PMID:
25403166
19.

Two peptides, cycloaspeptide A and nazumamide A from a sponge associated marine actinobacterium Salinispora sp.

Bose U, Hodson MP, Shaw PN, Fuerst JA, Hewavitharana AK.

Nat Prod Commun. 2014 Apr;9(4):545-6.

PMID:
24868880
20.

Effects of salinity on antibiotic production in sponge-derived Salinispora actinobacteria.

Ng YK, Hodson MP, Hewavitharana AK, Bose U, Shaw PN, Fuerst JA.

J Appl Microbiol. 2014 Jul;117(1):109-25. doi: 10.1111/jam.12507. Epub 2014 Apr 19.

21.

Discovering the recondite secondary metabolome spectrum of Salinispora species: a study of inter-species diversity.

Bose U, Hewavitharana AK, Vidgen ME, Ng YK, Shaw PN, Fuerst JA, Hodson MP.

PLoS One. 2014 Mar 12;9(3):e91488. doi: 10.1371/journal.pone.0091488. eCollection 2014.

22.

Beta-endorphin 1-31 biotransformation and cAMP modulation in inflammation.

Asvadi NH, Morgan M, Herath HM, Hewavitharana AK, Shaw PN, Cabot PJ.

PLoS One. 2014 Mar 11;9(3):e90380. doi: 10.1371/journal.pone.0090380. eCollection 2014.

23.

Biotransformation of beta-endorphin and possible therapeutic implications.

Asvadi NH, Morgan M, Hewavitharana AK, Shaw PN, Cabot PJ.

Front Pharmacol. 2014 Feb 19;5:18. doi: 10.3389/fphar.2014.00018. eCollection 2014. No abstract available.

24.

Bacterial production of the fungus-derived cholesterol-lowering agent mevinolin.

Bose U, Hodson MP, Shaw PN, Fuerst JA, Hewavitharana AK.

Biomed Chromatogr. 2014 Sep;28(9):1163-6. doi: 10.1002/bmc.3138. Epub 2014 Jan 29.

PMID:
24474532
25.

Recent trends in the determination of vitamin D.

Gomes FP, Shaw PN, Whitfield K, Koorts P, Hewavitharana AK.

Bioanalysis. 2013 Dec;5(24):3063-78. doi: 10.4155/bio.13.283. Review.

PMID:
24320131
26.

Current status of vitamin D assays: are they reliable and sufficiently informative for clinical studies?

Hewavitharana AK.

Bioanalysis. 2013 Jun;5(11):1325-7. doi: 10.4155/bio.13.88. No abstract available.

PMID:
23742299
27.

Anticancer activity of Carica papaya: a review.

Nguyen TT, Shaw PN, Parat MO, Hewavitharana AK.

Mol Nutr Food Res. 2013 Jan;57(1):153-64. doi: 10.1002/mnfr.201200388. Epub 2012 Dec 5. Review.

PMID:
23212988
28.

Developmental cycle and pharmaceutically relevant compounds of Salinispora actinobacteria isolated from Great Barrier Reef marine sponges.

Ng YK, Hewavitharana AK, Webb R, Shaw PN, Fuerst JA.

Appl Microbiol Biotechnol. 2013 Apr;97(7):3097-108. doi: 10.1007/s00253-012-4479-0. Epub 2012 Oct 19.

PMID:
23081774
29.

Dynorphin A 1-17 biotransformation in inflamed tissue, serum and trypsin solution analysed by liquid chromatography-tandem mass spectrometry.

Morgan M, Herath HM, Cabot PJ, Shaw PN, Hewavitharana AK.

Anal Bioanal Chem. 2012 Dec;404(10):3111-21. doi: 10.1007/s00216-012-6406-8. Epub 2012 Sep 22.

PMID:
23001306
30.

Monitoring potential prostate cancer biomarkers in urine by capillary electrophoresis-tandem mass spectrometry.

Soliman LC, Hui Y, Hewavitharana AK, Chen DD.

J Chromatogr A. 2012 Dec 7;1267:162-9. doi: 10.1016/j.chroma.2012.07.021. Epub 2012 Jul 14.

PMID:
22824219
31.

Study of beta endorphin metabolism in inflamed tissue, serum and trypsin solution by liquid chromatography-tandem mass spectrometric analysis.

Herath HM, Cabot PJ, Shaw PN, Hewavitharana AK.

Anal Bioanal Chem. 2012 Feb;402(6):2089-100. doi: 10.1007/s00216-011-5686-8. Epub 2012 Jan 10.

PMID:
22231512
32.

Bioactivity of mango flesh and peel extracts on peroxisome proliferator-activated receptor γ [PPARγ] activation and MCF-7 cell proliferation: fraction and fruit variability.

Wilkinson AS, Flanagan BM, Pierson JT, Hewavitharana AK, Dietzgen RG, Shaw PN, Roberts-Thomson SJ, Monteith GR, Gidley MJ.

J Food Sci. 2011 Jan-Feb;76(1):H11-8. doi: 10.1111/j.1750-3841.2010.01899.x. Epub 2010 Nov 18.

PMID:
21535682
33.

Matrix matching in liquid chromatography-mass spectrometry with stable isotope labelled internal standards--is it necessary?

Hewavitharana AK.

J Chromatogr A. 2011 Jan 14;1218(2):359-61. doi: 10.1016/j.chroma.2010.11.047. Epub 2010 Nov 27.

PMID:
21159347
34.
35.

Diversity of Mycobacterium species from marine sponges and their sensitivity to antagonism by sponge-derived rifamycin-synthesizing actinobacterium in the genus Salinispora.

Izumi H, Gauthier ME, Degnan BM, Ng YK, Hewavitharana AK, Shaw PN, Fuerst JA.

FEMS Microbiol Lett. 2010 Dec;313(1):33-40. doi: 10.1111/j.1574-6968.2010.02118.x. Epub 2010 Sep 30.

36.

Re: Florian Jentzmik, Carsten Stephan, Kurt Miller, et al. Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours. Eur Urol 2010;58:12-8.

Hewavitharana AK.

Eur Urol. 2010 Oct;58(4):e39-40; author reply e41-2. doi: 10.1016/j.eururo.2010.07.031. Epub 2010 Aug 4. No abstract available.

PMID:
20696519
37.

Effect of ionization suppression by trace impurities in mobile phase water on the accuracy of quantification by high-performance liquid chromatography/mass spectrometry.

Herath HM, Shaw PN, Cabot P, Hewavitharana AK.

Rapid Commun Mass Spectrom. 2010 Jun 15;24(11):1502-6. doi: 10.1002/rcm.4549.

PMID:
20486245
38.

Mango extracts and the mango component mangiferin promote endothelial cell migration.

Daud NH, Aung CS, Hewavitharana AK, Wilkinson AS, Pierson JT, Roberts-Thomson SJ, Shaw PN, Monteith GR, Gidley MJ, Parat MO.

J Agric Food Chem. 2010 Apr 28;58(8):5181-6. doi: 10.1021/jf100249s.

PMID:
20349963
39.

Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments.

Mutalik S, Hewavitharana AK, Shaw PN, Anissimov YG, Roberts MS, Parekh HS.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Nov 1;877(29):3556-62. doi: 10.1016/j.jchromb.2009.08.039. Epub 2009 Aug 29.

PMID:
19744897
40.

Development of an HPLC-MS/MS method for the selective determination of paracetamol metabolites in mouse urine.

Hewavitharana AK, Lee S, Dawson PA, Markovich D, Shaw PN.

Anal Biochem. 2008 Mar 1;374(1):106-11. Epub 2007 Nov 17.

PMID:
18082126
41.

Screening of rifamycin producing marine sponge bacteria by LC-MS-MS.

Hewavitharana AK, Shaw PN, Kim TK, Fuerst JA.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 1;852(1-2):362-6. Epub 2007 Feb 3.

PMID:
17301003
42.

Saponins from Quillaja saponaria Molina: isolation, characterization and ability to form immuno stimulatory complexes (ISCOMs).

Pham HL, Ross BP, McGeary RP, Shaw PN, Hewavitharana AK, Davies NM.

Curr Drug Deliv. 2006 Oct;3(4):389-97.

PMID:
17076641
43.

Disruption of NaS1 sulfate transport function in mice leads to enhanced acetaminophen-induced hepatotoxicity.

Lee S, Dawson PA, Hewavitharana AK, Shaw PN, Markovich D.

Hepatology. 2006 Jun;43(6):1241-7.

PMID:
16729303
44.

Shortcomings of protein removal prior to high performance liquid chromatographic analysis-A case study using method development for BAY 11-7082.

Hewavitharana AK, Hyde C, Thomas R, Shaw PN.

J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Apr 13;834(1-2):93-7. Epub 2006 Mar 10.

PMID:
16530027
45.

Discovery of a new source of rifamycin antibiotics in marine sponge actinobacteria by phylogenetic prediction.

Kim TK, Hewavitharana AK, Shaw PN, Fuerst JA.

Appl Environ Microbiol. 2006 Mar;72(3):2118-25.

46.

Quantitative GC-MS analysis of D(9)-tetrahydrocannabinol in fiber hemp varieties.

Hewavitharana AK, Golding G, Tempany G, King G, Holling N.

J Anal Toxicol. 2005 May-Jun;29(4):258-61.

PMID:
15975257
47.

Enhancing the ratio of molecular ions to non-covalent compounds in the electrospray interface of LC-MS in quantitative analysis.

Hewavitharana AK, Shaw PN.

Anal Bioanal Chem. 2005 Jun;382(4):1055-9. Epub 2005 May 12.

PMID:
15889242
48.

Effect of dietary tocopherols and tocotrienols on the antioxidant status and lipid stability of chicken.

Lanari MC, Hewavitharana AK, Becu C, de Jong S.

Meat Sci. 2004 Oct;68(2):155-62. doi: 10.1016/j.meatsci.2003.12.004.

PMID:
22062224
49.

Simultaneous determination of vitamin E homologs in chicken meat by liquid chromatography with fluorescence detection.

Hewavitharana AK, Lanari MC, Becu C.

J Chromatogr A. 2004 Feb 6;1025(2):313-7.

PMID:
14763816
50.

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