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Allosteric potentiation of a ligand-gated ion channel is mediated by access to a deep membrane-facing cavity.
Heusser SA, Lycksell M, Wang X, McComas SE, Howard RJ, Lindahl E.
Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10672-10677. doi: 10.1073/pnas.1809650115. Epub 2018 Oct 1.
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