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Items: 1 to 50 of 162

1.

Dispersal of harmful fruit fly pests by international trade and a loop-mediated isothermal amplification assay to prevent their introduction.

Blaser S, Heusser C, Diem H, Von Felten A, Gueuning M, Andreou M, Boonham N, Tomlinson J, Müller P, Utzinger J, Frey JE, Frey B, Bühlmann A.

Geospat Health. 2018 Nov 12;13(2). doi: 10.4081/gh.2018.726.

2.

Characterization of the in vitro and in vivo properties of CFZ533, a blocking and non-depleting anti-CD40 monoclonal antibody.

Ristov J, Espie P, Ulrich P, Sickert D, Flandre T, Dimitrova M, Müller-Ristig D, Weider D, Robert G, Schmutz P, Greutmann B, Cordoba-Castro F, Schneider MA, Warncke M, Kolbinger F, Cote S, Heusser C, Bruns C, Rush JS.

Am J Transplant. 2018 Dec;18(12):2895-2904. doi: 10.1111/ajt.14872. Epub 2018 May 24.

3.

A novel, blocking, Fc-silent anti-CD40 monoclonal antibody prolongs nonhuman primate renal allograft survival in the absence of B cell depletion.

Cordoba F, Wieczorek G, Audet M, Roth L, Schneider MA, Kunkler A, Stuber N, Erard M, Ceci M, Baumgartner R, Apolloni R, Cattini A, Robert G, Ristig D, Munz J, Haeberli L, Grau R, Sickert D, Heusser C, Espie P, Bruns C, Patel D, Rush JS.

Am J Transplant. 2015 Nov;15(11):2825-36. doi: 10.1111/ajt.13377. Epub 2015 Jul 2.

4.

CD47 fusion protein targets CD172a+ cells in Crohn's disease and dampens the production of IL-1β and TNF.

Baba N, Van VQ, Wakahara K, Rubio M, Fortin G, Panzini B, Soucy G, Wassef R, Richard C, Tamaz R, Lahaie R, Bernard EJ, Caussignac Y, Leduc R, Lougnarath R, Bergeron C, Racicot MA, Bergeron F, Panzini MA, Demetter P, Franchimont D, Schäkel K, Weckbecker G, Kolbinger F, Heusser C, Huber T, Welzenbach K, Sarfati M.

J Exp Med. 2013 Jun 3;210(6):1251-63. doi: 10.1084/jem.20122037. Epub 2013 May 13.

5.

Different adaptations of IgG effector function in human and nonhuman primates and implications for therapeutic antibody treatment.

Warncke M, Calzascia T, Coulot M, Balke N, Touil R, Kolbinger F, Heusser C.

J Immunol. 2012 May 1;188(9):4405-11. doi: 10.4049/jimmunol.1200090. Epub 2012 Mar 28.

6.

Sotrastaurin (AEB071) alone and in combination with cyclosporine A prolongs survival times of non-human primate recipients of life-supporting kidney allografts.

Bigaud M, Wieczorek G, Beerli C, Audet M, Blancher A, Heusser C, Morris RE, Wagner J.

Transplantation. 2012 Jan 27;93(2):156-64. doi: 10.1097/TP.0b013e31823cf92f.

PMID:
22179400
7.

3-Dimensional imaging for lower third molars: is there an implication for surgical removal?

Eyrich G, Seifert B, Matthews F, Matthiessen U, Heusser CK, Kruse AL, Obwegeser JA, Lübbers HT.

J Oral Maxillofac Surg. 2011 Jul;69(7):1867-72. doi: 10.1016/j.joms.2010.10.039. Epub 2011 Mar 21.

PMID:
21419547
8.

Anti-CD154 mAb and rapamycin induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation.

Muller YD, Mai G, Morel P, Serre-Beinier V, Gonelle-Gispert C, Yung GP, Ehirchiou D, Wyss JC, Bigenzahn S, Irla M, Heusser C, Golshayan D, Seebach JD, Wekerle T, Bühler LH.

PLoS One. 2010 Apr 26;5(4):e10352. doi: 10.1371/journal.pone.0010352.

9.

Strongly reduced alloreactivity and long-term survival times of cardiac allografts in Vav1- and Vav1/Vav2-knockout mice.

Weckbecker G, Bruns C, Fischer KD, Heusser C, Li J, Metzler B, Morris RE, Nuesslein-Hildesheim B, Raulf F, Wieczorek G, Zenke G.

Transpl Int. 2007 Apr;20(4):353-64.

10.

Smooth muscle cell proliferation but not neointimal formation is dependent on alloantibody in a murine model of intimal hyperplasia.

Soleimani B, Katopodis A, Wieczorek G, George AJ, Hornick PI, Heusser C.

Clin Exp Immunol. 2006 Dec;146(3):509-17.

11.

A novel low molecular weight inhibitor of dendritic cells and B cells blocks allergic inflammation.

Ettmayer P, Mayer P, Kalthoff F, Neruda W, Harrer N, Hartmann G, Epstein MM, Brinkmann V, Heusser C, Woisetschläger M.

Am J Respir Crit Care Med. 2006 Mar 15;173(6):599-606. Epub 2005 Dec 30.

PMID:
16387807
12.

The role of non-deletional tolerance mechanisms in a murine model of mixed chimerism with costimulation blockade.

Bigenzahn S, Blaha P, Koporc Z, Pree I, Selzer E, Bergmeister H, Wrba F, Heusser C, Wagner K, Muehlbacher F, Wekerle T.

Am J Transplant. 2005 Jun;5(6):1237-47.

13.

Pharmacodynamics in the development of new immunosuppressive drugs.

Burkhart C, Heusser C, Morris RE, Raulf F, Weckbecker G, Weitz-Schmidt G, Welzenbach K.

Ther Drug Monit. 2004 Dec;26(6):588-92. Review.

PMID:
15570181
15.

Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells.

Boulay A, Zumstein-Mecker S, Stephan C, Beuvink I, Zilbermann F, Haller R, Tobler S, Heusser C, O'Reilly T, Stolz B, Marti A, Thomas G, Lane HA.

Cancer Res. 2004 Jan 1;64(1):252-61.

16.

Argyrins, immunosuppressive cyclic peptides from myxobacteria. I. Production, isolation, physico-chemical and biological properties.

Sasse F, Steinmetz H, Schupp T, Petersen F, Memmert K, Hofmann H, Heusser C, Brinkmann V, von Matt P, Höfle G, Reichenbach H.

J Antibiot (Tokyo). 2002 Jun;55(6):543-51.

17.
18.

Pulmonary inflammation induced by a recombinant Brugia malayi gamma-glutamyl transpeptidase homolog: involvement of humoral autoimmune responses.

Gounni AS, Spanel-Borowski K, Palacios M, Heusser C, Moncada S, Lobos E.

Mol Med. 2001 May;7(5):344-54.

19.

Aromatic quinolinecarboxamides as selective, orally active antibody production inhibitors for prevention of acute xenograft rejection.

Papageorgiou C, von Matt A, Joergensen J, Andersen E, Wagner K, Beerli C, Than T, Borer X, Florineth A, Rihs G, Schreier MH, Weckbecker G, Heusser C.

J Med Chem. 2001 Jun 7;44(12):1986-92.

PMID:
11384243
20.

Allergen-derived long peptide immunotherapy down-regulates specific IgE response and protects from anaphylaxis.

von Garnier C, Astori M, Kettner A, Dufour N, Heusser C, Corradin G, Spertini F.

Eur J Immunol. 2000 Jun;30(6):1638-45.

21.

Anti-interleukin 5 but not anti-IgE prevents airway inflammation and airway hyperresponsiveness.

Hamelmann E, Cieslewicz G, Schwarze J, Ishizuka T, Joetham A, Heusser C, Gelfand EW.

Am J Respir Crit Care Med. 1999 Sep;160(3):934-41.

PMID:
10471622
22.

Suppression of immediate and late responses to antigen by a non-anaphylactogenic anti-IgE antibody in a murine model of asthma.

Haile S, Lefort J, Eum SY, Dumarey C, Huerre M, Heusser C, Vargaftig BB.

Eur Respir J. 1999 May;13(5):961-9.

23.

Enhancement of human IL-4 activity by soluble IL-4 receptors in vitro.

Jung T, Wagner K, Neumann C, Heusser CH.

Eur J Immunol. 1999 Mar;29(3):864-71.

24.

Treatment of allergic airways disease with anti-IgE.

Holgate ST, Corne J, Jardieu P, Fick RB, Heusser CH.

Allergy. 1998;53(45 Suppl):83-8. Review. No abstract available.

PMID:
9788714
25.

Detection of and discrimination between total and free human interleukin-4 and free soluble interleukin-4 receptor by ELISA.

Jung T, Bews JP, Enssle KH, Wagner K, Neumann C, Heusser CH.

J Immunol Methods. 1998 Aug 1;217(1-2):41-50.

PMID:
9776573
26.

Frequencies of T cells expressing interleukin-4 and interleukin-5 in atopic asthmatic children. Comparison with atopic asthmatic adults.

Krug N, Jung T, Napp U, Wagner K, Schultze-Werninghaus G, Heusser C, Rieger CH, Schauer U, Fabel H.

Am J Respir Crit Care Med. 1998 Sep;158(3):754-9.

PMID:
9731001
27.

Inhibition of human airway sensitization by a novel monoclonal anti-IgE antibody, 17-9.

Rabe KF, Watson N, Dent G, Morton BE, Wagner K, Magnussen H, Heusser CH.

Am J Respir Crit Care Med. 1998 May;157(5 Pt 1):1429-35.

PMID:
9603119
28.

Therapeutic potential of anti-IgE antibodies.

Heusser C, Jardieu P.

Curr Opin Immunol. 1997 Dec;9(6):805-13. Review.

PMID:
9492982
29.

A subset of CD8+ T cells from allergic patients produce IL-4 and stimulate IgE production in vitro.

Meissner N, Kussebi F, Jung T, Ratti H, Baumgarten C, Werfel T, Heusser C, Renz H.

Clin Exp Allergy. 1997 Dec;27(12):1402-11.

PMID:
9433935
30.

Glucocorticoids inhibit human antigen-specific and enhance total IgE and IgG4 production due to differential effects on T and B cells in vitro.

Akdis CA, Blesken T, Akdis M, Alkan SS, Heusser CH, Blaser K.

Eur J Immunol. 1997 Sep;27(9):2351-7.

PMID:
9341780
31.

Opposite role for interleukin-4 and interferon-gamma on CD30 and lymphocyte activation gene-3 (LAG-3) expression by activated naive T cells.

Annunziato F, Manetti R, Cosmi L, Galli G, Heusser CH, Romagnani S, Maggi E.

Eur J Immunol. 1997 Sep;27(9):2239-44.

PMID:
9341765
32.

Demonstration of the therapeutic potential of non-anaphylactogenic anti-IgE antibodies in murine models of skin reaction, lung function and inflammation.

Heusser CH, Wagner K, Bews JP, Coyle A, Bertrand C, Einsle K, Kips J, Eum SY, Lefort J, Vargaftig BB.

Int Arch Allergy Immunol. 1997 May-Jul;113(1-3):231-5.

PMID:
9130531
33.

The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: efficacy, safety, and pharmacokinetics.

Corne J, Djukanovic R, Thomas L, Warner J, Botta L, Grandordy B, Gygax D, Heusser C, Patalano F, Richardson W, Kilchherr E, Staehelin T, Davis F, Gordon W, Sun L, Liou R, Wang G, Chang TW, Holgate S.

J Clin Invest. 1997 Mar 1;99(5):879-87.

34.
35.

Role of IL-13 in CD4 T cell-dependent IgE production in atopy.

Levy F, Kristofic C, Heusser C, Brinkmann V.

Int Arch Allergy Immunol. 1997 Jan;112(1):49-58.

PMID:
8980464
36.

The development of IgE+ memory B cells following primary IgE immune responses.

Le Gros G, Schultze N, Walti S, Einsle K, Finkelman F, Kosco-Vilbois MH, Heusser C.

Eur J Immunol. 1996 Dec;26(12):3042-7.

PMID:
8977302
37.

A strict requirement of interleukin-4 for interleukin-4 induction in antigen-stimulated human memory T cells.

Breit S, Steinhoff M, Blaser K, Heusser CH, Sebald W, Levine AD, Röcken M.

Eur J Immunol. 1996 Aug;26(8):1860-5.

PMID:
8765032
39.

Different cytokine patterns in bronchial biopsies in asthma and chronic bronchitis.

Mueller R, Chanez P, Campbell AM, Bousquet J, Heusser C, Bullock GR.

Respir Med. 1996 Feb;90(2):79-85.

40.

Interhemispheric correlation of late pleistocene glacial events.

Lowell TV, Heusser CJ, Andersen BG, Moreno PI, Hauser A, Heusser LE, Schlüchter C, Marchant DR, Denton GH.

Science. 1995 Sep 15;269(5230):1541-9.

PMID:
17789444
41.

Interleukin-4 and interleukin-5 are rarely co-expressed by human T cells.

Jung T, Schauer U, Rieger C, Wagner K, Einsle K, Neumann C, Heusser C.

Eur J Immunol. 1995 Aug;25(8):2413-6.

PMID:
7664804
42.

Interleukin-4 is required for the induction of lung Th2 mucosal immunity.

Coyle AJ, Le Gros G, Bertrand C, Tsuyuki S, Heusser CH, Kopf M, Anderson GP.

Am J Respir Cell Mol Biol. 1995 Jul;13(1):54-9.

PMID:
7598937
43.
44.

Immunolocalization of intracellular interleukin-4 in normal human peripheral blood basophils.

Mueller R, Heusser CH, Rihs S, Brunner T, Bullock GR, Dahinden CA.

Eur J Immunol. 1994 Dec;24(12):2935-40.

PMID:
7805719
45.

Neutralizing monoclonal antibodies define two different functional sites in human interleukin-4.

Reusch P, Arnold S, Heusser C, Wagner K, Weston B, Sebald W.

Eur J Biochem. 1994 Jun 1;222(2):491-9.

46.

Release and inactivation of interleukin-4 by mast cells.

Tunon de Lara JM, Okayama Y, McEuen AR, Heusser CH, Church MK, Walls AF.

Ann N Y Acad Sci. 1994 May 28;725:50-8. Review. No abstract available.

PMID:
8031009
47.

In vitro maturation of human neonatal CD4 T lymphocytes. II. Cytokines present at priming modulate the development of lymphokine production.

Demeure CE, Wu CY, Shu U, Schneider PV, Heusser C, Yssel H, Delespesse G.

J Immunol. 1994 May 15;152(10):4775-82.

PMID:
7909823
48.

Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines.

Bradding P, Roberts JA, Britten KM, Montefort S, Djukanovic R, Mueller R, Heusser CH, Howarth PH, Holgate ST.

Am J Respir Cell Mol Biol. 1994 May;10(5):471-80.

PMID:
8179909
49.

Regulation of IgE and IgG4 responses by allergen specific T-cell clones to bee venom phospholipase A2 in vitro.

Carballido JM, Carballido-Perrig N, Oberli-Schrämmli A, Heusser CH, Blaser K.

J Allergy Clin Immunol. 1994 Apr;93(4):758-67.

PMID:
8163785
50.

[Immune response and pathophysiology of the allergic reaction].

Heusser CH, Brinkmann V.

Ther Umsch. 1994 Jan;51(1):14-8. Review. German.

PMID:
8146808

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