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Items: 1 to 50 of 145

1.

Fission yeast Myo2: Molecular organization and diffusion in the cytoplasm.

Friend JE, Sayyad WA, Arasada R, McCormick CD, Heuser JE, Pollard TD.

Cytoskeleton (Hoboken). 2018 Apr;75(4):164-173. doi: 10.1002/cm.21425. Epub 2017 Dec 14.

2.

Injury-induced actin cytoskeleton reorganization in podocytes revealed by super-resolution microscopy.

Suleiman HY, Roth R, Jain S, Heuser JE, Shaw AS, Miner JH.

JCI Insight. 2017 Aug 17;2(16). pii: 94137. doi: 10.1172/jci.insight.94137. eCollection 2017 Aug 17.

3.

Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency.

Sone M, Morone N, Nakamura T, Tanaka A, Okita K, Woltjen K, Nakagawa M, Heuser JE, Yamada Y, Yamanaka S, Yamamoto T.

Cell Metab. 2017 May 2;25(5):1103-1117.e6. doi: 10.1016/j.cmet.2017.04.017.

4.

Intrinsic repair protects cells from pore-forming toxins by microvesicle shedding.

Romero M, Keyel M, Shi G, Bhattacharjee P, Roth R, Heuser JE, Keyel PA.

Cell Death Differ. 2017 May;24(5):798-808. doi: 10.1038/cdd.2017.11. Epub 2017 Feb 10.

5.

Polymer-coated pH-responsive high-density lipoproteins.

Kim H, Okamoto H, Felber AE, Polomska A, Morone N, Heuser JE, Leroux JC, Murakami T.

J Control Release. 2016 Apr 28;228:132-140. doi: 10.1016/j.jconrel.2016.03.005. Epub 2016 Mar 6.

PMID:
26959846
6.

The modeling of Alzheimer's disease by the overexpression of mutant Presenilin 1 in human embryonic stem cells.

Honda M, Minami I, Tooi N, Morone N, Nishioka H, Uemura K, Kinoshita A, Heuser JE, Nakatsuji N, Aiba K.

Biochem Biophys Res Commun. 2016 Jan 15;469(3):587-92. doi: 10.1016/j.bbrc.2015.12.025. Epub 2015 Dec 10.

7.

Eisosome Ultrastructure and Evolution in Fungi, Microalgae, and Lichens.

Lee JH, Heuser JE, Roth R, Goodenough U.

Eukaryot Cell. 2015 Oct;14(10):1017-42. doi: 10.1128/EC.00106-15. Epub 2015 Aug 7.

8.

Allosteric activation of ADAMTS13 by von Willebrand factor.

Muia J, Zhu J, Gupta G, Haberichter SL, Friedman KD, Feys HB, Deforche L, Vanhoorelbeke K, Westfield LA, Roth R, Tolia NH, Heuser JE, Sadler JE.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18584-9. doi: 10.1073/pnas.1413282112. Epub 2014 Dec 15.

9.
10.

Diffusion-coupled molecular assembly: structuring of coordination polymers across multiple length scales.

Hirai K, Reboul J, Morone N, Heuser JE, Furukawa S, Kitagawa S.

J Am Chem Soc. 2014 Oct 22;136(42):14966-73. doi: 10.1021/ja507971r. Epub 2014 Oct 7.

PMID:
25254320
11.

Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes.

Metkar SS, Marchioretto M, Antonini V, Lunelli L, Wang B, Gilbert RJ, Anderluh G, Roth R, Pooga M, Pardo J, Heuser JE, Serra MD, Froelich CJ.

Cell Death Differ. 2015 Jan;22(1):74-85. doi: 10.1038/cdd.2014.110. Epub 2014 Aug 22.

12.

Mesoscopic metal nanoparticles doubly functionalized with natural and engineered lipidic dispersants for therapeutics.

Murakami T, Nakatsuji H, Morone N, Heuser JE, Ishidate F, Hashida M, Imahori H.

ACS Nano. 2014 Jul 22;8(7):7370-6. doi: 10.1021/nn5024818. Epub 2014 Jun 19.

PMID:
24945782
13.

A 3D sphere culture system containing functional polymers for large-scale human pluripotent stem cell production.

Otsuji TG, Bin J, Yoshimura A, Tomura M, Tateyama D, Minami I, Yoshikawa Y, Aiba K, Heuser JE, Nishino T, Hasegawa K, Nakatsuji N.

Stem Cell Reports. 2014 Apr 24;2(5):734-45. doi: 10.1016/j.stemcr.2014.03.012. eCollection 2014 May 6. Erratum in: Stem Cell Reports. 2014 May 6;2(5):746.

14.

Kinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E.

Vitre B, Gudimchuk N, Borda R, Kim Y, Heuser JE, Cleveland DW, Grishchuk EL.

Mol Biol Cell. 2014 Aug 1;25(15):2272-81. doi: 10.1091/mbc.E14-01-0698. Epub 2014 Jun 11.

15.

Helical DNA origami tubular structures with various sizes and arrangements.

Endo M, Yamamoto S, Emura T, Hidaka K, Morone N, Heuser JE, Sugiyama H.

Angew Chem Int Ed Engl. 2014 Jul 14;53(29):7484-90. doi: 10.1002/anie.201402973. Epub 2014 May 30.

PMID:
24888699
16.

Structure of cellular ESCRT-III spirals and their relationship to HIV budding.

Cashikar AG, Shim S, Roth R, Maldazys MR, Heuser JE, Hanson PI.

Elife. 2014 May 30;3. doi: 10.7554/eLife.02184.

17.

Actin scaffolding by clathrin heavy chain is required for skeletal muscle sarcomere organization.

Vassilopoulos S, Gentil C, Lainé J, Buclez PO, Franck A, Ferry A, Précigout G, Roth R, Heuser JE, Brodsky FM, Garcia L, Bonne G, Voit T, Piétri-Rouxel F, Bitoun M.

J Cell Biol. 2014 May 12;205(3):377-93. doi: 10.1083/jcb.201309096. Epub 2014 May 5.

18.

A 3D Sphere Culture System Containing Functional Polymers for Large-Scale Human Pluripotent Stem Cell Production.

Otsuji TG, Bin J, Yoshimura A, Tomura M, Tateyama D, Minami I, Yoshikawa Y, Aiba K, Heuser JE, Nishino T, Hasegawa K, Nakatsuji N.

Stem Cell Reports. 2014 May 6;2(5):746. doi: 10.1016/j.stemcr.2014.04.013. Epub 2014 May 8. No abstract available.

19.

Nanoscale protein architecture of the kidney glomerular basement membrane.

Suleiman H, Zhang L, Roth R, Heuser JE, Miner JH, Shaw AS, Dani A.

Elife. 2013 Oct 8;2:e01149. doi: 10.7554/eLife.01149. Erratum in: Elife. 2013;2:e1663.

20.

Exclusive photothermal heat generation by a gadolinium bis(naphthalocyanine) complex and inclusion into modified high-density lipoprotein nanocarriers for therapeutic applications.

Mathew S, Murakami T, Nakatsuji H, Okamoto H, Morone N, Heuser JE, Hashida M, Imahori H.

ACS Nano. 2013 Oct 22;7(10):8908-16. doi: 10.1021/nn403384k. Epub 2013 Oct 2.

PMID:
24053139
21.

Reduction of streptolysin O (SLO) pore-forming activity enhances inflammasome activation.

Keyel PA, Roth R, Yokoyama WM, Heuser JE, Salter RD.

Toxins (Basel). 2013 Jun 6;5(6):1105-18. doi: 10.3390/toxins5061105.

22.

Exosomes: looking back three decades and into the future.

Harding CV, Heuser JE, Stahl PD.

J Cell Biol. 2013 Feb 18;200(4):367-71. doi: 10.1083/jcb.201212113. Erratum in: J Cell Biol. 2013 Apr 29;201(3):485.

23.

Development of a reentrant arrhythmia model in human pluripotent stem cell-derived cardiac cell sheets.

Kadota S, Minami I, Morone N, Heuser JE, Agladze K, Nakatsuji N.

Eur Heart J. 2013 Apr;34(15):1147-56. doi: 10.1093/eurheartj/ehs418. Epub 2012 Nov 30.

PMID:
23201623
24.

A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions.

Minami I, Yamada K, Otsuji TG, Yamamoto T, Shen Y, Otsuka S, Kadota S, Morone N, Barve M, Asai Y, Tenkova-Heuser T, Heuser JE, Uesugi M, Aiba K, Nakatsuji N.

Cell Rep. 2012 Nov 29;2(5):1448-60. doi: 10.1016/j.celrep.2012.09.015. Epub 2012 Oct 25.

25.

Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery.

Tanaka T, Takahashi K, Yamane M, Tomida S, Nakamura S, Oshima K, Niwa A, Nishikomori R, Kambe N, Hara H, Mitsuyama M, Morone N, Heuser JE, Yamamoto T, Watanabe A, Sato-Otsubo A, Ogawa S, Asaka I, Heike T, Yamanaka S, Nakahata T, Saito MK.

Blood. 2012 Aug 9;120(6):1299-308. doi: 10.1182/blood-2012-03-417881. Epub 2012 Jun 21.

26.

Stathmin regulates microtubule dynamics and microtubule organizing center polarization in activated T cells.

Filbert EL, Le Borgne M, Lin J, Heuser JE, Shaw AS.

J Immunol. 2012 Jun 1;188(11):5421-7. doi: 10.4049/jimmunol.1200242. Epub 2012 Apr 23.

27.

Utilization of photoinduced charge-separated state of donor-acceptor-linked molecules for regulation of cell membrane potential and ion transport.

Numata T, Murakami T, Kawashima F, Morone N, Heuser JE, Takano Y, Ohkubo K, Fukuzumi S, Mori Y, Imahori H.

J Am Chem Soc. 2012 Apr 11;134(14):6092-5. doi: 10.1021/ja3007275. Epub 2012 Apr 2.

PMID:
22449129
28.

The origins and evolution of freeze-etch electron microscopy.

Heuser JE.

J Electron Microsc (Tokyo). 2011;60 Suppl 1:S3-29. doi: 10.1093/jmicro/dfr044. Review.

29.

The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3.

Yuan S, Yu X, Asara JM, Heuser JE, Ludtke SJ, Akey CW.

Structure. 2011 Aug 10;19(8):1084-96. doi: 10.1016/j.str.2011.07.001.

30.

Streptolysin O clearance through sequestration into blebs that bud passively from the plasma membrane.

Keyel PA, Loultcheva L, Roth R, Salter RD, Watkins SC, Yokoyama WM, Heuser JE.

J Cell Sci. 2011 Jul 15;124(Pt 14):2414-23. doi: 10.1242/jcs.076182. Epub 2011 Jun 21.

31.

Regulation of Hip1r by epsin controls the temporal and spatial coupling of actin filaments to clathrin-coated pits.

Brady RJ, Damer CK, Heuser JE, O'Halloran TJ.

J Cell Sci. 2010 Nov 1;123(Pt 21):3652-61. doi: 10.1242/jcs.066852. Epub 2010 Oct 5.

32.

Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system.

Wu M, Huang B, Graham M, Raimondi A, Heuser JE, Zhuang X, De Camilli P.

Nat Cell Biol. 2010 Sep;12(9):902-8. doi: 10.1038/ncb2094. Epub 2010 Aug 22. Erratum in: Nat Cell Biol. 2010 Oct;12(10):1021. Nat Cell Biol. 2010 Sep;12(9). doi: 10.1038/ncb2094.

33.

Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth.

Soman NR, Baldwin SL, Hu G, Marsh JN, Lanza GM, Heuser JE, Arbeit JM, Wickline SA, Schlesinger PH.

J Clin Invest. 2009 Sep;119(9):2830-42. doi: 10.1172/JCI38842. Epub 2009 Aug 10.

34.

Coordinate regulation of glycan degradation and polysaccharide capsule biosynthesis by a prominent human gut symbiont.

Martens EC, Roth R, Heuser JE, Gordon JI.

J Biol Chem. 2009 Jul 3;284(27):18445-57. doi: 10.1074/jbc.M109.008094. Epub 2009 Apr 29.

35.

Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates.

Ren PH, Lauckner JE, Kachirskaia I, Heuser JE, Melki R, Kopito RR.

Nat Cell Biol. 2009 Feb;11(2):219-25. doi: 10.1038/ncb1830. Epub 2009 Jan 18.

36.

Integrin alpha(v)beta(3) on human endothelial cells binds von Willebrand factor strings under fluid shear stress.

Huang J, Roth R, Heuser JE, Sadler JE.

Blood. 2009 Feb 12;113(7):1589-97. doi: 10.1182/blood-2008-05-158584. Epub 2008 Oct 16.

37.

The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis.

Keyel PA, Thieman JR, Roth R, Erkan E, Everett ET, Watkins SC, Heuser JE, Traub LM.

Mol Biol Cell. 2008 Dec;19(12):5309-26. doi: 10.1091/mbc.E08-07-0712. Epub 2008 Oct 8.

38.

A comparative analysis of Dmc1 and Rad51 nucleoprotein filaments.

Sheridan SD, Yu X, Roth R, Heuser JE, Sehorn MG, Sung P, Egelman EH, Bishop DK.

Nucleic Acids Res. 2008 Jul;36(12):4057-66. doi: 10.1093/nar/gkn352. Epub 2008 Jun 4.

39.

CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether.

Kim Y, Heuser JE, Waterman CM, Cleveland DW.

J Cell Biol. 2008 May 5;181(3):411-9. doi: 10.1083/jcb.200802189. Epub 2008 Apr 28.

40.

Plasma membrane deformation by circular arrays of ESCRT-III protein filaments.

Hanson PI, Roth R, Lin Y, Heuser JE.

J Cell Biol. 2008 Jan 28;180(2):389-402. doi: 10.1083/jcb.200707031. Epub 2008 Jan 21.

41.

Assembly of Weibel-Palade body-like tubules from N-terminal domains of von Willebrand factor.

Huang RH, Wang Y, Roth R, Yu X, Purvis AR, Heuser JE, Egelman EH, Sadler JE.

Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):482-7. doi: 10.1073/pnas.0710079105. Epub 2008 Jan 8.

42.

Visualization of the herpes simplex virus portal in situ by cryo-electron tomography.

Cardone G, Winkler DC, Trus BL, Cheng N, Heuser JE, Newcomb WW, Brown JC, Steven AC.

Virology. 2007 May 10;361(2):426-34. Epub 2006 Dec 22.

43.

A single common portal for clathrin-mediated endocytosis of distinct cargo governed by cargo-selective adaptors.

Keyel PA, Mishra SK, Roth R, Heuser JE, Watkins SC, Traub LM.

Mol Biol Cell. 2006 Oct;17(10):4300-17. Epub 2006 Jul 26.

44.

Molecular switches involving the AP-2 beta2 appendage regulate endocytic cargo selection and clathrin coat assembly.

Edeling MA, Mishra SK, Keyel PA, Steinhauser AL, Collins BM, Roth R, Heuser JE, Owen DJ, Traub LM.

Dev Cell. 2006 Mar;10(3):329-42.

45.

Epsin 1 is a polyubiquitin-selective clathrin-associated sorting protein.

Hawryluk MJ, Keyel PA, Mishra SK, Watkins SC, Heuser JE, Traub LM.

Traffic. 2006 Mar;7(3):262-81. Erratum in: Traffic. 2006 Jul;7(7):927.

46.

Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts.

Lapaque N, Forquet F, de Chastellier C, Mishal Z, Jolly G, Moreno E, Moriyon I, Heuser JE, He HT, Gorvel JP.

Cell Microbiol. 2006 Feb;8(2):197-206.

PMID:
16441431
47.

Release of host-derived membrane vesicles following pilus-mediated adhesion of Neisseria gonorrhoeae.

Gill DB, Spitzer D, Koomey M, Heuser JE, Atkinson JP.

Cell Microbiol. 2005 Nov;7(11):1672-83.

PMID:
16207253
48.

Drosophila Spire is an actin nucleation factor.

Quinlan ME, Heuser JE, Kerkhoff E, Mullins RD.

Nature. 2005 Jan 27;433(7024):382-8.

PMID:
15674283
49.

Dual engagement regulation of protein interactions with the AP-2 adaptor alpha appendage.

Mishra SK, Hawryluk MJ, Brett TJ, Keyel PA, Dupin AL, Jha A, Heuser JE, Fremont DH, Traub LM.

J Biol Chem. 2004 Oct 29;279(44):46191-203. Epub 2004 Aug 2.

50.

TorsinA in the nuclear envelope.

Naismith TV, Heuser JE, Breakefield XO, Hanson PI.

Proc Natl Acad Sci U S A. 2004 May 18;101(20):7612-7. Epub 2004 May 10.

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