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1.

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT Jr, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y; Alzheimer Disease Genetics Consortium (ADGC); European Alzheimer’s Disease Initiative (EADI); Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE); Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Pilotto A, Bullido MJ, Peters O, Crane PK, Bennett D, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL, Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM, Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, O'Donovan MC, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA.

Nat Genet. 2019 Aug 15. doi: 10.1038/s41588-019-0495-7. [Epub ahead of print]

PMID:
31417202
2.

Remission in schizophrenia - What are we measuring? Comparing the consensus remission criteria to a CGI-based definition of remission and to remission in major depression.

Schennach R, Obermeier M, Spellmann I, Seemüller F, Musil R, Jäger M, Schmauss M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Bauer M, Adli M, Zeiler J, Bender W, Kronmüller KT, Ising M, Brieger P, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Möller HJ, Riedel M.

Schizophr Res. 2019 Jul;209:185-192. doi: 10.1016/j.schres.2019.04.022. Epub 2019 May 25.

PMID:
31138482
3.

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT Jr, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y, Pilotto A, Bullido MJ, Peters O, Crane PK, Bennett D, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL, Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM, Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, C O'Donovan M, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA; Alzheimer Disease Genetics Consortium (ADGC),; European Alzheimer’s Disease Initiative (EADI),; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE),; Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES),.

Nat Genet. 2019 Mar;51(3):414-430. doi: 10.1038/s41588-019-0358-2. Epub 2019 Feb 28. Erratum in: Nat Genet. 2019 Aug 15;:.

PMID:
30820047
4.

Editorial.

Heuser I, Dantzer R.

Psychoneuroendocrinology. 2019 Feb;100:iii. doi: 10.1016/j.psyneuen.2019.01.004. No abstract available.

PMID:
30642472
5.

Inhibition of monoamine oxidase activity by repetitive transcranial magnetic stimulation: implications for inter-train interval and frequency.

Kaczmarczyk M, Regen F, Heuser I, Bajbouj M, Hellmann-Regen J.

Eur Arch Psychiatry Clin Neurosci. 2018 Dec 17. doi: 10.1007/s00406-018-0969-0. [Epub ahead of print]

PMID:
30560291
6.

Anti-inflammatory effects of minocycline are mediated by retinoid signaling.

Clemens V, Regen F, Le Bret N, Heuser I, Hellmann-Regen J.

BMC Neurosci. 2018 Sep 21;19(1):58. doi: 10.1186/s12868-018-0460-x.

7.

Correlation of CSF- and MRI-Biomarkers and Progression of Cognitive Decline in an Open Label MCI Trial.

Joachim LK, Frölich L, Rüther E, Wiltfang J, Maier W, Kornhuber J, Bauer C, Heuser I, Peters O.

J Prev Alzheimers Dis. 2018;5(3):202-206. doi: 10.14283/jpad.2018.5.

PMID:
29972214
8.

Subtypes of depression and their overlap in a naturalistic inpatient sample of major depressive disorder.

Musil R, Seemüller F, Meyer S, Spellmann I, Adli M, Bauer M, Kronmüller KT, Brieger P, Laux G, Bender W, Heuser I, Fisher R, Gaebel W, Schennach R, Möller HJ, Riedel M.

Int J Methods Psychiatr Res. 2018 Mar;27(1). doi: 10.1002/mpr.1569. Epub 2017 Jun 14.

PMID:
29498147
9.

Retinoic Acid Enhances Apolipoprotein E Synthesis in Human Macrophages.

Clemens V, Regen F, Le Bret N, Heuser I, Hellmann-Regen J.

J Alzheimers Dis. 2018;61(4):1295-1300. doi: 10.3233/JAD-170823.

PMID:
29376871
10.

Neuroprotektive Ansätze bei der antidepressiven Behandlung.

Heuser I.

Drug Res (Stuttg). 2017 Nov;67(S 01):S23-S24. doi: 10.1055/s-0043-118158. Epub 2017 Oct 25. German. No abstract available.

11.

Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer's dementia.

Frölich L, Peters O, Lewczuk P, Gruber O, Teipel SJ, Gertz HJ, Jahn H, Jessen F, Kurz A, Luckhaus C, Hüll M, Pantel J, Reischies FM, Schröder J, Wagner M, Rienhoff O, Wolf S, Bauer C, Schuchhardt J, Heuser I, Rüther E, Henn F, Maier W, Wiltfang J, Kornhuber J.

Alzheimers Res Ther. 2017 Oct 10;9(1):84. doi: 10.1186/s13195-017-0301-7.

12.

Add-on Antidepressants in the Naturalistic Treatment of Schizophrenia Spectrum Disorder - When, Who, and How?

Schennach R, Obermeier M, Seemüller F, Jäger M, Schmauss M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Spellmann I, Musil R, Möller HJ, Riedel M.

Pharmacopsychiatry. 2017 Jul;50(4):136-144. doi: 10.1055/s-0043-106436. Epub 2017 May 15.

PMID:
28505669
13.

[Psychosocial care of refugees in Germany : Insights from the emergency relief and development aid].

Bajbouj M, Alabdullah J, Ahmad S, Schidem S, Zellmann H, Schneider F, Heuser I.

Nervenarzt. 2018 Jan;89(1):1-7. doi: 10.1007/s00115-017-0326-y. Review. German.

PMID:
28405699
14.

Clozapine-induced agranulocytosis: Evidence for an immune-mediated mechanism from a patient-specific in-vitro approach.

Regen F, Herzog I, Hahn E, Ruehl C, Le Bret N, Dettling M, Heuser I, Hellmann-Regen J.

Toxicol Appl Pharmacol. 2017 Feb 1;316:10-16. doi: 10.1016/j.taap.2016.12.003. Epub 2016 Dec 6.

PMID:
27939987
15.

Validity of remission and recovery criteria for schizophrenia and major depression: comparison of the results of two one-year follow-up naturalistic studies.

Spellmann I, Schennach R, Seemüller F, Meyer S, Musil R, Jäger M, Schmauß M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Bauer M, Adli M, Zeiler J, Bender W, Kronmüller KT, Ising M, Brieger P, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Riedel M, Möller HJ.

Eur Arch Psychiatry Clin Neurosci. 2017 Jun;267(4):303-313. doi: 10.1007/s00406-016-0741-2. Epub 2016 Oct 26.

PMID:
27785605
16.

Hypothalamic-Pituitary-Adrenocortical Dysfunction in Elderly, Male Marathon Runners: Feedback Sensitivity, Stress Response, and Effects on Verbal Memory.

Deuschle M, Gotthardt U, Schweiger U, Dettling M, Holsboer F, Heuser I.

Neuroendocrinology. 2017;105(2):150-156. doi: 10.1159/000450856. Epub 2016 Sep 28.

PMID:
27677093
17.

Mineralocorticoid receptor function in depressed patients and healthy individuals.

Hinkelmann K, Hellmann-Regen J, Wingenfeld K, Kuehl LK, Mews M, Fleischer J, Heuser I, Otte C.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Nov 3;71:183-8. doi: 10.1016/j.pnpbp.2016.08.003. Epub 2016 Aug 9.

PMID:
27519144
18.

[Dementia Competence Network. Results and outlook].

Peters O, Heuser I, Frölich L, Rüther E, Rienhoff O, Kornhuber J, Wiltfang J, Maier W.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Apr;59(4):438-43. doi: 10.1007/s00103-016-2314-y. German.

PMID:
26979717
19.

Correspondence arising: Modafinil for cognitive neuroenhancement in health non-sleep-deprived-subjects.

Repantis D, Maier LJ, Heuser I.

Eur Neuropsychopharmacol. 2016 Feb;26(2):392-393. doi: 10.1016/j.euroneuro.2015.12.016. Epub 2015 Dec 11. No abstract available.

PMID:
26706695
20.

The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment.

Koppara A, Wolfsgruber S, Kleineidam L, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, Pantel J, Rienhoff O, Rüther E, Henn F, Wiltfang J, Maier W, Jessen F, Kornhuber J, Wagner M.

J Alzheimers Dis. 2016;49(2):547-60. doi: 10.3233/JAD-150257.

PMID:
26484902
21.

Combined treatment with memantine and galantamine-CR compared with galantamine-CR only in antidementia drug naïve patients with mild-to-moderate Alzheimer's disease.

Peters O, Fuentes M, Joachim LK, Jessen F, Luckhaus C, Kornhuber J, Pantel J, Hüll M, Schmidtke K, Rüther E, Möller HJ, Kurz A, Wiltfang J, Maier W, Wiese B, Frölich L, Heuser I.

Alzheimers Dement (N Y). 2015 Oct 19;1(3):198-204. doi: 10.1016/j.trci.2015.10.001. eCollection 2015 Nov.

22.

Challenging the understanding of significant improvement and outcome in schizophrenia - the concept of reliable and clinically significant change methods.

Schennach R, Möller HJ, Obermeier M, Seemüller F, Jäger M, Schmauss M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Musil R, Spellmann I, Riedel M.

Int J Methods Psychiatr Res. 2016 Mar;25(1):3-11. doi: 10.1002/mpr.1476. Epub 2015 Jul 14.

PMID:
26178421
23.

Inhibition of brain retinoic acid catabolism: a mechanism for minocycline's pleiotropic actions?

Regen F, Le Bret N, Hildebrand M, Herzog I, Heuser I, Hellmann-Regen J.

World J Biol Psychiatry. 2016 Dec;17(8):634-640. Epub 2015 Jun 5.

PMID:
26047390
24.

Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study.

Morgen K, Schneider M, Frölich L, Tost H, Plichta MM, Kölsch H, Rakebrandt F, Rienhoff O, Jessen F, Peters O, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, Hampel H, Teipel SJ, Pantel J, Heuser I, Wiltfang J, Rüther E, Kornhuber J, Maier W, Meyer-Lindenberg A.

Alzheimers Res Ther. 2015 May 15;7(1):27. doi: 10.1186/s13195-015-0111-8. eCollection 2015.

25.

Direct inhibition of retinoic acid catabolism by fluoxetine.

Hellmann-Regen J, Uhlemann R, Regen F, Heuser I, Otte C, Endres M, Gertz K, Kronenberg G.

J Neural Transm (Vienna). 2015 Sep;122(9):1329-38. doi: 10.1007/s00702-015-1407-3. Epub 2015 May 17.

PMID:
25981674
26.

Inhibition of retinoic acid catabolism by minocycline: evidence for a novel mode of action?

Regen F, Hildebrand M, Le Bret N, Herzog I, Heuser I, Hellmann-Regen J.

Exp Dermatol. 2015 Jun;24(6):473-6. doi: 10.1111/exd.12692. Epub 2015 Apr 16.

PMID:
25810318
27.

Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI.

Wolfsgruber S, Jessen F, Koppara A, Kleineidam L, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, Pantel J, Rienhoff O, Rüther E, Henn F, Wiltfang J, Maier W, Kornhuber J, Wagner M.

Neurology. 2015 Mar 24;84(12):1261-8. doi: 10.1212/WNL.0000000000001399. Epub 2015 Feb 25.

PMID:
25716354
28.

READING and FEELING: the effects of a literature-based intervention designed to increase emotional competence in second and third graders.

Kumschick IR, Beck L, Eid M, Witte G, Klann-Delius G, Heuser I, Steinlein R, Menninghaus W.

Front Psychol. 2014 Dec 16;5:1448. doi: 10.3389/fpsyg.2014.01448. eCollection 2014.

29.

What are depressive symptoms in acutely ill patients with schizophrenia spectrum disorder?

Schennach R, Riedel M, Obermeier M, Seemüller F, Jäger M, Schmauss M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Möller HJ.

Eur Psychiatry. 2015 Jan;30(1):43-50. doi: 10.1016/j.eurpsy.2014.11.001. Epub 2014 Dec 22.

PMID:
25541347
30.

Variation in the corticotropin-releasing hormone receptor 1 (CRHR1) gene modulates age effects on working memory.

Grimm S, Gärtner M, Fuge P, Fan Y, Weigand A, Feeser M, Aust S, Heekeren HR, Jacobs A, Heuser I, Bajbouj M.

J Psychiatr Res. 2015 Feb;61:57-63. doi: 10.1016/j.jpsychires.2014.12.001. Epub 2014 Dec 16.

PMID:
25541005
31.

Stimulation of the mineralocorticoid receptor improves memory in young and elderly healthy individuals.

Hinkelmann K, Wingenfeld K, Kuehl LK, Fleischer J, Heuser I, Wiedemann K, Otte C.

Neurobiol Aging. 2015 Feb;36(2):919-24. doi: 10.1016/j.neurobiolaging.2014.09.008. Epub 2014 Sep 16.

PMID:
25442112
32.

Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type.

Popp J, Wolfsgruber S, Heuser I, Peters O, Hüll M, Schröder J, Möller HJ, Lewczuk P, Schneider A, Jahn H, Luckhaus C, Perneczky R, Frölich L, Wagner M, Maier W, Wiltfang J, Kornhuber J, Jessen F.

Neurobiol Aging. 2015 Feb;36(2):601-7. doi: 10.1016/j.neurobiolaging.2014.10.031. Epub 2014 Oct 31.

PMID:
25435336
33.

It's in the mix: psychological distress differs between combinations of alexithymic facets.

Alkan Härtwig E, Crayen C, Heuser I, Eid M.

Front Psychol. 2014 Nov 12;5:1259. doi: 10.3389/fpsyg.2014.01259. eCollection 2014.

34.

What are residual symptoms in schizophrenia spectrum disorder? Clinical description and 1-year persistence within a naturalistic trial.

Schennach R, Riedel M, Obermeier M, Spellmann I, Musil R, Jäger M, Schmauss M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Möller HJ.

Eur Arch Psychiatry Clin Neurosci. 2015 Mar;265(2):107-16. doi: 10.1007/s00406-014-0528-2. Epub 2014 Sep 27.

PMID:
25261210
35.

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey.

Bocchetta M, Galluzzi S, Kehoe PG, Aguera E, Bernabei R, Bullock R, Ceccaldi M, Dartigues JF, de Mendonça A, Didic M, Eriksdotter M, Félician O, Frölich L, Gertz HJ, Hallikainen M, Hasselbalch SG, Hausner L, Heuser I, Jessen F, Jones RW, Kurz A, Lawlor B, Lleo A, Martinez-Lage P, Mecocci P, Mehrabian S, Monsch A, Nobili F, Nordberg A, Rikkert MO, Orgogozo JM, Pasquier F, Peters O, Salmon E, Sánchez-Castellano C, Santana I, Sarazin M, Traykov L, Tsolaki M, Visser PJ, Wallin ÅK, Wilcock G, Wilkinson D, Wolf H, Yener G, Zekry D, Frisoni GB.

Alzheimers Dement. 2015 Feb;11(2):195-206.e1. doi: 10.1016/j.jalz.2014.06.006. Epub 2014 Aug 20.

PMID:
25150733
36.

Reply to: Continuation antidepressant strategies after electroconvulsive therapy: ultrabrief pulse versus cognitive-behavioral therapy.

Brakemeier EL, Merkl A, Wilbertz G, Quante A, Regen F, Bührsch N, Hall FV, Kischkel E, Anghelescu I, Danker-Hopfe H, Heuser I, Kathmann N, Bajbouj M.

Biol Psychiatry. 2015 Feb 1;77(3):e9. doi: 10.1016/j.biopsych.2014.06.023. Epub 2014 Jul 9. No abstract available.

PMID:
25092630
37.

Personality Pathology of Adults With Autism Spectrum Disorder Without Accompanying Intellectual Impairment in Comparison to Adults With Personality Disorders.

Strunz S, Westphal L, Ritter K, Heuser I, Dziobek I, Roepke S.

J Autism Dev Disord. 2015 Dec;45(12):4026-38. doi: 10.1007/s10803-014-2183-x.

PMID:
25022250
38.

Memory concerns, memory performance and risk of dementia in patients with mild cognitive impairment.

Wolfsgruber S, Wagner M, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, Pantel J, Rienhoff O, Rüther E, Henn F, Wiltfang J, Maier W, Kornhuber J, Jessen F.

PLoS One. 2014 Jul 14;9(7):e100812. doi: 10.1371/journal.pone.0100812. eCollection 2014.

39.

Effect of specific psychotherapy for chronic depression on neural responses to emotional faces.

Klein JP, Becker B, Hurlemann R, Scheibe C, Colla M, Heuser I.

J Affect Disord. 2014 Sep;166:93-7. doi: 10.1016/j.jad.2014.04.055. Epub 2014 May 9.

PMID:
25012415
40.

Adjunctive lithium treatment in the prevention of suicidal behavior in patients with depression and comorbid personality disorders.

Rombold F, Lauterbach E, Felber W, Mueller-Oerlinghausen B, Ahrens B, Bronisch T, Kilb B, Lewitzka U, Richter K, Broocks A, Heuser I, Hohagen F, Quante A.

Int J Psychiatry Clin Pract. 2014 Oct;18(4):300-3. doi: 10.3109/13651501.2014.940052. Epub 2014 Jul 23.

PMID:
24994476
41.

Differential effects of early life stress on hippocampus and amygdala volume as a function of emotional abilities.

Aust S, Stasch J, Jentschke S, Alkan Härtwig E, Koelsch S, Heuser I, Bajbouj M.

Hippocampus. 2014 Sep;24(9):1094-101. doi: 10.1002/hipo.22293. Epub 2014 Apr 26.

PMID:
24753197
42.

Do tetracyclines and erythromycin exert anti-acne effects by inhibition of P450-mediated degradation of retinoic acid?

Hellmann-Regen J, Herzog I, Fischer N, Heuser I, Regen F.

Exp Dermatol. 2014 Apr;23(4):290-3. doi: 10.1111/exd.12358.

PMID:
24690039
43.

Genetic interaction of PICALM and APOE is associated with brain atrophy and cognitive impairment in Alzheimer's disease.

Morgen K, Ramirez A, Frölich L, Tost H, Plichta MM, Kölsch H, Rakebrandt F, Rienhoff O, Jessen F, Peters O, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, Hampel H, Teipel SJ, Pantel J, Heuser I, Wiltfang J, Rüther E, Kornhuber J, Maier W, Meyer-Lindenberg A.

Alzheimers Dement. 2014 Oct;10(5 Suppl):S269-76. doi: 10.1016/j.jalz.2013.11.001. Epub 2014 Mar 6.

PMID:
24613704
44.

Three-Year long-term outcome of 458 naturalistically treated inpatients with major depressive episode: severe relapse rates and risk factors.

Seemüller F, Meier S, Obermeier M, Musil R, Bauer M, Adli M, Kronmüller K, Holsboer F, Brieger P, Laux G, Bender W, Heuser I, Zeiler J, Gaebel W, Riedel M, Falkai P, Möller HJ.

Eur Arch Psychiatry Clin Neurosci. 2014 Oct;264(7):567-75. doi: 10.1007/s00406-014-0495-7. Epub 2014 Mar 4.

PMID:
24590257
45.

Cognitive-behavioral therapy as continuation treatment to sustain response after electroconvulsive therapy in depression: a randomized controlled trial.

Brakemeier EL, Merkl A, Wilbertz G, Quante A, Regen F, Bührsch N, van Hall F, Kischkel E, Danker-Hopfe H, Anghelescu I, Heuser I, Kathmann N, Bajbouj M.

Biol Psychiatry. 2014 Aug 1;76(3):194-202. doi: 10.1016/j.biopsych.2013.11.030. Epub 2013 Dec 12. Erratum in: Biol Psychiatry. 2014 Sep 1;76(5):430.

PMID:
24462229
46.

Electroconvulsive therapy-induced brain plasticity determines therapeutic outcome in mood disorders.

Dukart J, Regen F, Kherif F, Colla M, Bajbouj M, Heuser I, Frackowiak RS, Draganski B.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1156-61. doi: 10.1073/pnas.1321399111. Epub 2013 Dec 30.

47.

Hypocretin in cerebrospinal fluid is positively correlated with Tau and pTau.

Deuschle M, Schilling C, Leweke FM, Enning F, Pollmächer T, Esselmann H, Wiltfang J, Frölich L, Heuser I.

Neurosci Lett. 2014 Feb 21;561:41-5. doi: 10.1016/j.neulet.2013.12.036. Epub 2013 Dec 25.

PMID:
24373987
48.

Striking growth-inhibitory effects of minocycline on human prostate cancer cell lines.

Regen F, Heuser I, Herzog I, Hellmann-Regen J.

Urology. 2014 Feb;83(2):509.e1-6. doi: 10.1016/j.urology.2013.10.029. Epub 2013 Dec 19.

PMID:
24360070
49.

UV-A emission from fluorescent energy-saving light bulbs alters local retinoic acid homeostasis.

Hellmann-Regen J, Heuser I, Regen F.

Photochem Photobiol Sci. 2013 Dec;12(12):2177-85. doi: 10.1039/c3pp50206f.

PMID:
24135972
50.

Childhood maltreatment and adult proinflammatory status in patients with major depression.

Zeugmann S, Buehrsch N, Bajbouj M, Heuser I, Anghelescu I, Quante A.

Psychiatr Danub. 2013 Sep;25(3):227-35.

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