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Items: 1 to 50 of 51

1.

The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse.

Bégay V, Baumeier C, Zimmermann K, Heuser A, Leutz A.

Sci Rep. 2018 May 30;8(1):8417. doi: 10.1038/s41598-018-26579-y.

2.

Nitric oxide-sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction.

Wilck N, Markó L, Balogh A, Kräker K, Herse F, Bartolomaeus H, Szijártó IA, Gollasch M, Reichhart N, Strauss O, Heuser A, Brockschnieder D, Kretschmer A, Lesche R, Sohler F, Stasch JP, Sandner P, Luft FC, Müller DN, Dechend R, Haase N.

JCI Insight. 2018 Feb 22;3(4). pii: 96006. doi: 10.1172/jci.insight.96006. [Epub ahead of print]

3.

The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis.

Althof N, Goetzke CC, Kespohl M, Voss K, Heuser A, Pinkert S, Kaya Z, Klingel K, Beling A.

EMBO Mol Med. 2018 Feb;10(2):200-218. doi: 10.15252/emmm.201708089.

4.

Preserved heart function after left ventricular pressure overload in adult mice subjected to neonatal cardiac hypoplasia.

Heinecke K, Heuser A, Blaschke F, Jux C, Thierfelder L, Drenckhahn JD.

J Dev Orig Health Dis. 2018 Feb;9(1):112-124. doi: 10.1017/S2040174417000514. Epub 2017 Jul 24.

PMID:
28737122
5.

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.

Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, Szigeti-Buck K, Yi CX, Schriever SC, Tattikota SG, Carlo AS, Moroni M, Siemens J, Heuser A, van der Weyden L, Birkenfeld AL, Niendorf T, Poulet JFA, Horvath TL, Tschöp MH, Heinig M, Trajkovski M, Haucke V, Poy MN.

Nat Neurosci. 2017 Aug;20(8):1096-1103. doi: 10.1038/nn.4590. Epub 2017 Jun 19.

6.

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.

Lodka D, Pahuja A, Geers-Knörr C, Scheibe RJ, Nowak M, Hamati J, Köhncke C, Purfürst B, Kanashova T, Schmidt S, Glass DJ, Morano I, Heuser A, Kraft T, Bassel-Duby R, Olson EN, Dittmar G, Sommer T, Fielitz J.

J Cachexia Sarcopenia Muscle. 2016 May;7(2):165-80. doi: 10.1002/jcsm.12057. Epub 2015 Sep 7.

7.

Activation of Peroxisome Proliferator-Activated Receptor-δ as Novel Therapeutic Strategy to Prevent In-Stent Restenosis and Stent Thrombosis.

Hytönen J, Leppänen O, Braesen JH, Schunck WH, Mueller D, Jung F, Mrowietz C, Jastroch M, von Bergwelt-Baildon M, Kappert K, Heuser A, Drenckhahn JD, Pieske B, Thierfelder L, Ylä-Herttuala S, Blaschke F.

Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1534-48. doi: 10.1161/ATVBAHA.115.306962. Epub 2016 Jun 9.

8.

CD74-Downregulation of Placental Macrophage-Trophoblastic Interactions in Preeclampsia.

Przybyl L, Haase N, Golic M, Rugor J, Solano ME, Arck PC, Gauster M, Huppertz B, Emontzpohl C, Stoppe C, Bernhagen J, Leng L, Bucala R, Schulz H, Heuser A, Weedon-Fekjær MS, Johnsen GM, Peetz D, Luft FC, Staff AC, Müller DN, Dechend R, Herse F.

Circ Res. 2016 Jun 24;119(1):55-68. doi: 10.1161/CIRCRESAHA.116.308304. Epub 2016 May 19.

9.

Inhibition of chymotryptic-like standard proteasome activity exacerbates doxorubicin-induced cytotoxicity in primary cardiomyocytes.

Spur EM, Althof N, Respondek D, Klingel K, Heuser A, Overkleeft HS, Voigt A.

Toxicology. 2016 Apr 15;353-354:34-47. doi: 10.1016/j.tox.2016.04.010. Epub 2016 May 4.

PMID:
27155237
10.

Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.

Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, Thierfelder L, Donath S, Drenckhahn JD.

J Mol Cell Cardiol. 2016 Aug;97:1-14. doi: 10.1016/j.yjmcc.2016.04.007. Epub 2016 Apr 20.

PMID:
27106802
11.

Biological fractionation of stable Ca isotopes in Göttingen minipigs as a physiological model for Ca homeostasis in humans.

Heuser A, Eisenhauer A, Scholz-Ahrens KE, Schrezenmeir J.

Isotopes Environ Health Stud. 2016 Dec;52(6):633-48. doi: 10.1080/10256016.2016.1151017. Epub 2016 Mar 21.

PMID:
26999569
12.

Tracing copper derived from pig manure in calcareous soils and soil leachates by 65Cu labeling.

Ostermann A, He Y, Siemens J, Welp G, Heuser A, Wombacher F, Münker C, Xue Q, Lin X, Amelung W.

Environ Sci Technol. 2015 Apr 7;49(7):4609-17. doi: 10.1021/es504945e. Epub 2015 Mar 16.

PMID:
25742507
13.

Impaired myocardial development resulting in neonatal cardiac hypoplasia alters postnatal growth and stress response in the heart.

Drenckhahn JD, Strasen J, Heinecke K, Langner P, Yin KV, Skole F, Hennig M, Spallek B, Fischer R, Blaschke F, Heuser A, Cox TC, Black MJ, Thierfelder L.

Cardiovasc Res. 2015 Apr 1;106(1):43-54. doi: 10.1093/cvr/cvv028. Epub 2015 Feb 6.

PMID:
25661081
14.

Nonproliferative and proliferative lesions of the rat and mouse female reproductive system.

Dixon D, Alison R, Bach U, Colman K, Foley GL, Harleman JH, Haworth R, Herbert R, Heuser A, Long G, Mirsky M, Regan K, Van Esch E, Westwood FR, Vidal J, Yoshida M.

J Toxicol Pathol. 2014;27(3-4 Suppl):1S-107S. doi: 10.1293/tox.27.1S. Review.

15.

First in line: prioritizing receipt of Social Security disability benefits based on likelihood of death during adjudication.

Rasch EK, Huynh M, Ho PS, Heuser A, Houtenville A, Chan L.

Med Care. 2014 Nov;52(11):944-50. doi: 10.1097/MLR.0000000000000204.

16.

Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling.

Markó L, Henke N, Park JK, Spallek B, Qadri F, Balogh A, Apel IJ, Oravecz-Wilson KI, Choi M, Przybyl L, Binger KJ, Haase N, Wilck N, Heuser A, Fokuhl V, Ruland J, Lucas PC, McAllister-Lucas LM, Luft FC, Dechend R, Müller DN.

Hypertension. 2014 Nov;64(5):1032-9. doi: 10.1161/HYPERTENSIONAHA.114.03900. Epub 2014 Sep 2.

17.
18.

Selective inhibition of PDE4 in Wistar rats can lead to dilatation in testis, efferent ducts, and epididymis and subsequent formation of sperm granulomas.

Heuser A, Mecklenburg L, Ockert D, Kohler M, Kemkowski J.

Toxicol Pathol. 2013;41(4):615-27. doi: 10.1177/0192623312463783. Epub 2012 Nov 29.

PMID:
23197197
19.

Role of the SP2 domain and its proteolytic cleavage in HIV-1 structural maturation and infectivity.

de Marco A, Heuser AM, Glass B, Kräusslich HG, Müller B, Briggs JA.

J Virol. 2012 Dec;86(24):13708-16. doi: 10.1128/JVI.01704-12. Epub 2012 Oct 10.

20.

The glucose-lowering effects of the PDE4 inhibitors roflumilast and roflumilast-N-oxide in db/db mice.

Vollert S, Kaessner N, Heuser A, Hanauer G, Dieckmann A, Knaack D, Kley HP, Beume R, Weiss-Haljiti C.

Diabetologia. 2012 Oct;55(10):2779-2788. doi: 10.1007/s00125-012-2632-z. Epub 2012 Jul 13.

PMID:
22790061
21.

TAT-apoptosis repressor with caspase recruitment domain protein transduction rescues mice from fulminant liver failure.

An J, Harms C, Lättig-Tünnemann G, Sellge G, Mandić AD, Malato Y, Heuser A, Endres M, Trautwein C, Donath S.

Hepatology. 2012 Aug;56(2):715-26. doi: 10.1002/hep.25697. Epub 2012 Jul 3.

PMID:
22392694
22.

Local tolerance of intraarticular administration of lornoxicam into the rabbit knee joint.

Schroeder S, Heuser A, Tellmann A, Goebel KJ, Woehrmann T.

Rheumatol Int. 2012 Sep;32(9):2661-7. doi: 10.1007/s00296-011-2012-x. Epub 2011 Jul 26.

PMID:
21789617
23.

A simple fluorescence based assay for quantification of human immunodeficiency virus particle release.

Hermle J, Anders M, Heuser AM, Müller B.

BMC Biotechnol. 2010 Apr 20;10:32. doi: 10.1186/1472-6750-10-32.

24.

Alpha1A-adrenergic receptor-directed autoimmunity induces left ventricular damage and diastolic dysfunction in rats.

Wenzel K, Wallukat G, Qadri F, Hubner N, Schulz H, Hummel O, Herse F, Heuser A, Fischer R, Heidecke H, Luft FC, Muller DN, Dietz R, Dechend R.

PLoS One. 2010 Feb 24;5(2):e9409. doi: 10.1371/journal.pone.0009409.

25.

A pilot study on the use of natural calcium isotope (44Ca/40Ca) fractionation in urine as a proxy for the human body calcium balance.

Heuser A, Eisenhauer A.

Bone. 2010 Apr;46(4):889-96. doi: 10.1016/j.bone.2009.11.037. Epub 2009 Dec 11.

PMID:
20004263
26.

Growth arrest specific protein 6 participates in DOCA-induced target-organ damage.

Park JK, Theuer S, Kirsch T, Lindschau C, Klinge U, Heuser A, Plehm R, Todiras M, Carmeliet P, Haller H, Luft FC, Muller DN, Fiebeler A.

Hypertension. 2009 Aug;54(2):359-64. doi: 10.1161/HYPERTENSIONAHA.109.129460. Epub 2009 Jun 29.

27.

Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease.

Gramlich M, Michely B, Krohne C, Heuser A, Erdmann B, Klaassen S, Hudson B, Magarin M, Kirchner F, Todiras M, Granzier H, Labeit S, Thierfelder L, Gerull B.

J Mol Cell Cardiol. 2009 Sep;47(3):352-8. doi: 10.1016/j.yjmcc.2009.04.014. Epub 2009 May 4.

28.

Role of the multidomain protein spinophilin in blood pressure and cardiac function regulation.

da Costa-Goncalves AC, Tank J, Plehm R, Diedrich A, Todiras M, Gollasch M, Heuser A, Wellner M, Bader M, Jordan J, Luft FC, Gross V.

Hypertension. 2008 Oct;52(4):702-7. doi: 10.1161/HYPERTENSIONAHA.108.114355. Epub 2008 Aug 18.

29.

Mutations in sarcomere protein genes in left ventricular noncompaction.

Klaassen S, Probst S, Oechslin E, Gerull B, Krings G, Schuler P, Greutmann M, Hürlimann D, Yegitbasi M, Pons L, Gramlich M, Drenckhahn JD, Heuser A, Berger F, Jenni R, Thierfelder L.

Circulation. 2008 Jun 3;117(22):2893-901. doi: 10.1161/CIRCULATIONAHA.107.746164. Epub 2008 May 27.

30.

Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.

Monti J, Fischer J, Paskas S, Heinig M, Schulz H, Gösele C, Heuser A, Fischer R, Schmidt C, Schirdewan A, Gross V, Hummel O, Maatz H, Patone G, Saar K, Vingron M, Weldon SM, Lindpaintner K, Hammock BD, Rohde K, Dietz R, Cook SA, Schunck WH, Luft FC, Hubner N.

Nat Genet. 2008 May;40(5):529-37. doi: 10.1038/ng.129.

PMID:
18443590
31.

Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension.

Fischer R, Dechend R, Qadri F, Markovic M, Feldt S, Herse F, Park JK, Gapelyuk A, Schwarz I, Zacharzowsky UB, Plehm R, Safak E, Heuser A, Schirdewan A, Luft FC, Schunck WH, Muller DN.

Hypertension. 2008 Feb;51(2):540-6. Epub 2007 Dec 24.

32.

Televideo assessment using Functional Reach Test and European Stroke Scale.

Palsbo SE, Dawson SJ, Savard L, Goldstein M, Heuser A.

J Rehabil Res Dev. 2007;44(5):659-64.

33.

Telerehabilitation using the Rutgers Master II glove following carpal tunnel release surgery: proof-of-concept.

Heuser A, Kourtev H, Winter S, Fensterheim D, Burdea G, Hentz V, Forducey P.

IEEE Trans Neural Syst Rehabil Eng. 2007 Mar;15(1):43-9.

PMID:
17436875
34.

Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy.

Heuser A, Plovie ER, Ellinor PT, Grossmann KS, Shin JT, Wichter T, Basson CT, Lerman BB, Sasse-Klaassen S, Thierfelder L, MacRae CA, Gerull B.

Am J Hum Genet. 2006 Dec;79(6):1081-8. Epub 2006 Oct 3.

35.

A novel locus for dilated cardiomyopathy, diffuse myocardial fibrosis, and sudden death on chromosome 10q25-26.

Ellinor PT, Sasse-Klaassen S, Probst S, Gerull B, Shin JT, Toeppel A, Heuser A, Michely B, Yoerger DM, Song BS, Pilz B, Krings G, Coplin B, Lange PE, Dec GW, Hennies HC, Thierfelder L, MacRae CA.

J Am Coll Cardiol. 2006 Jul 4;48(1):106-11. Epub 2006 Jun 21.

36.

Identification of a novel frameshift mutation in the giant muscle filament titin in a large Australian family with dilated cardiomyopathy.

Gerull B, Atherton J, Geupel A, Sasse-Klaassen S, Heuser A, Frenneaux M, McNabb M, Granzier H, Labeit S, Thierfelder L.

J Mol Med (Berl). 2006 Jun;84(6):478-83. Epub 2006 May 6.

PMID:
16733766
37.

Cardiac troponin C-L29Q, related to hypertrophic cardiomyopathy, hinders the transduction of the protein kinase A dependent phosphorylation signal from cardiac troponin I to C.

Schmidtmann A, Lindow C, Villard S, Heuser A, Mügge A, Gessner R, Granier C, Jaquet K.

FEBS J. 2005 Dec;272(23):6087-97.

38.

Mesenteritis precedes vasculitis in the rat mesentery after subacute administration of a phosphodiesterase type 4 inhibitor.

Mecklenburg L, Heuser A, Juengling T, Kohler M, Foell R, Ockert D, Tuch K, Bode G.

Toxicol Lett. 2006 May 5;163(1):54-64. Epub 2005 Oct 24.

PMID:
16246509
39.

Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.

Gerull B, Heuser A, Wichter T, Paul M, Basson CT, McDermott DA, Lerman BB, Markowitz SM, Ellinor PT, MacRae CA, Peters S, Grossmann KS, Drenckhahn J, Michely B, Sasse-Klaassen S, Birchmeier W, Dietz R, Breithardt G, Schulze-Bahr E, Thierfelder L.

Nat Genet. 2004 Nov;36(11):1162-4. Epub 2004 Oct 17. Erratum in: Nat Genet. 2005 Jan;37(1):106.

PMID:
15489853
40.

Revised guides for organ sampling and trimming in rats and mice--Part 3. A joint publication of the RITA and NACAD groups.

Morawietz G, Ruehl-Fehlert C, Kittel B, Bube A, Keane K, Halm S, Heuser A, Hellmann J; RITA Group; NACAD Group.

Exp Toxicol Pathol. 2004 Jul;55(6):433-49.

PMID:
15384249
41.

Novel gene locus for autosomal dominant left ventricular noncompaction maps to chromosome 11p15.

Sasse-Klaassen S, Probst S, Gerull B, Oechslin E, Nürnberg P, Heuser A, Jenni R, Hennies HC, Thierfelder L.

Circulation. 2004 Jun 8;109(22):2720-3. Epub 2004 Jun 1.

42.

Oral L-ornithine-L-aspartate therapy of chronic hepatic encephalopathy: results of a placebo-controlled double-blind study.

Stauch S, Kircheis G, Adler G, Beckh K, Ditschuneit H, Görtelmeyer R, Hendricks R, Heuser A, Karoff C, Malfertheiner P, Mayer D, Rösch W, Steffens J.

J Hepatol. 1998 May;28(5):856-64.

PMID:
9625322
43.

Configurations of diastereomeric hydroxyethylene isosteres strongly affect biological activities of a series of specific inhibitors of human-immunodeficiency-virus proteinase.

Konvalinka J, Litera J, Weber J, Vondrásek J, Hradílek M, Soucek M, Pichová I, Majer P, Strop P, Sedlácek J, Heuser AM, Kottler H, Kräusslich HG.

Eur J Biochem. 1997 Dec 1;250(2):559-66.

44.

Peptide inhibitors of HIV-1 and HIV-2 proteases: a comparative study.

Pichová I, Weber J, Litera J, Konvalinka J, Vondrásek J, Soucek M, Strop P, Majer P, Heuser AM, Kraeusslich HG.

Leukemia. 1997 Apr;11 Suppl 3:120-2.

PMID:
9209317
45.

[Topoisomerase I inhibitor with potential radiosensitizing effect].

Sauer R, Heuser A.

Strahlenther Onkol. 1997 Mar;173(3):125-30. Review. German.

PMID:
9122851
47.
48.

Proteolytic processing of particle-associated retroviral polyproteins by homologous and heterologous viral proteinases.

Konvalinka J, Heuser AM, Hruskova-Heidingsfeldova O, Vogt VM, Sedlacek J, Strop P, Kräusslich HG.

Eur J Biochem. 1995 Feb 15;228(1):191-8.

49.

Airborne differential absorption lidar system for measurements of atmospheric water vapor and aerosols.

Higdon NS, Browell EV, Ponsardin P, Grossmann BE, Butler CF, Chyba TH, Mayo MN, Allen RJ, Heuser AW, Grant WB, Ismail S, Mayor SD, Carter AF.

Appl Opt. 1994 Sep 20;33(27):6422-38. doi: 10.1364/AO.33.006422.

PMID:
20941181
50.

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