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Items: 1 to 50 of 71

1.

Ramified rolling circle amplification for synthesis of nucleosomal DNA sequences.

van Emmerik CL, Gachulincova I, Lobbia VR, Daniëls MA, Heus HA, Soufi A, Nelissen FHT, van Ingen H.

Anal Biochem. 2020 Jan 1;588:113469. doi: 10.1016/j.ab.2019.113469. Epub 2019 Oct 9.

2.

Dissipative adaptation in driven self-assembly leading to self-dividing fibrils.

Te Brinke E, Groen J, Herrmann A, Heus HA, Rivas G, Spruijt E, Huck WTS.

Nat Nanotechnol. 2018 Sep;13(9):849-855. doi: 10.1038/s41565-018-0192-1. Epub 2018 Jul 16.

PMID:
30013214
3.

Biomimetic Stress Sensitive Hydrogel Controlled by DNA Nanoswitches.

Deshpande SR, Hammink R, Nelissen FHT, Rowan AE, Heus HA.

Biomacromolecules. 2017 Oct 9;18(10):3310-3317. doi: 10.1021/acs.biomac.7b00964. Epub 2017 Sep 28.

4.

A membrane-anchored aptamer sensor for probing IFNγ secretion by single cells.

Qiu L, Wimmers F, Weiden J, Heus HA, Tel J, Figdor CG.

Chem Commun (Camb). 2017 Jul 13;53(57):8066-8069. doi: 10.1039/c7cc03576d.

PMID:
28675396
5.

Stable isotope labeling methods for DNA.

Nelissen FHT, Tessari M, Wijmenga SS, Heus HA.

Prog Nucl Magn Reson Spectrosc. 2016 Aug;96:89-108. doi: 10.1016/j.pnmrs.2016.06.001. Epub 2016 Jun 20. Review.

PMID:
27573183
6.

Protein Synthesis in Coupled and Uncoupled Cell-Free Prokaryotic Gene Expression Systems.

Hansen MM, Ventosa Rosquelles M, Yelleswarapu M, Maas RJ, van Vugt-Jonker AJ, Heus HA, Huck WT.

ACS Synth Biol. 2016 Dec 16;5(12):1433-1440. Epub 2016 Jul 5.

PMID:
27306580
7.

Cell-Like Nanostructured Environments Alter Diffusion and Reaction Kinetics in Cell-Free Gene Expression.

Hansen MM, Paffenholz S, Foschepoth D, Heus HA, Thiele J, Huck WT.

Chembiochem. 2016 Feb 2;17(3):228-32. doi: 10.1002/cbic.201500560. Epub 2015 Dec 17.

PMID:
26603600
8.

Macromolecular crowding creates heterogeneous environments of gene expression in picolitre droplets.

Hansen MM, Meijer LH, Spruijt E, Maas RJ, Rosquelles MV, Groen J, Heus HA, Huck WT.

Nat Nanotechnol. 2016 Feb;11(2):191-7. doi: 10.1038/nnano.2015.243. Epub 2015 Oct 26.

9.

Associative Interactions in Crowded Solutions of Biopolymers Counteract Depletion Effects.

Groen J, Foschepoth D, te Brinke E, Boersma AJ, Imamura H, Rivas G, Heus HA, Huck WT.

J Am Chem Soc. 2015 Oct 14;137(40):13041-8. doi: 10.1021/jacs.5b07898. Epub 2015 Sep 29.

PMID:
26383885
10.

Production of Homogeneous Recombinant RNA Using a tRNA Scaffold and Hammerhead Ribozymes.

Nelissen FH, Heus HA, Wijmenga SS.

Methods Mol Biol. 2015;1316:33-44. doi: 10.1007/978-1-4939-2730-2_4.

PMID:
25967051
11.

Enzymatic preparation of multimilligram amounts of pure single-stranded DNA samples for material and analytical sciences.

Nelissen FH, Goossens EP, Tessari M, Heus HA.

Anal Biochem. 2015 Apr 15;475:68-73. doi: 10.1016/j.ab.2015.01.014. Epub 2015 Jan 29.

PMID:
25637680
12.

DNA-functionalized hydrogels for confined membrane-free in vitro transcription/translation.

Thiele J, Ma Y, Foschepoth D, Hansen MM, Steffen C, Heus HA, Huck WT.

Lab Chip. 2014 Aug 7;14(15):2651-6. doi: 10.1039/c3lc51427g. Epub 2014 Mar 24.

PMID:
24663810
13.

Structural and thermodynamic signatures that define pseudotriloop RNA hairpins.

van der Werf R, Wijmenga SS, Heus HA, Olsthoorn RC.

RNA. 2013 Dec;19(12):1833-9. doi: 10.1261/rna.039636.113. Epub 2013 Oct 24.

14.

Enhanced transcription rates in membrane-free protocells formed by coacervation of cell lysate.

Sokolova E, Spruijt E, Hansen MM, Dubuc E, Groen J, Chokkalingam V, Piruska A, Heus HA, Huck WT.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11692-7. doi: 10.1073/pnas.1222321110. Epub 2013 Jul 1.

15.

Fast production of homogeneous recombinant RNA--towards large-scale production of RNA.

Nelissen FH, Leunissen EH, van de Laar L, Tessari M, Heus HA, Wijmenga SS.

Nucleic Acids Res. 2012 Jul;40(13):e102. doi: 10.1093/nar/gks292. Epub 2012 Mar 28.

16.

Unusual loop-sequence flexibility of the proximal RNA replication element in EMCV.

Zoll J, Hahn MM, Gielen P, Heus HA, Melchers WJ, van Kuppeveld FJ.

PLoS One. 2011;6(9):e24818. doi: 10.1371/journal.pone.0024818. Epub 2011 Sep 14.

17.

Atomic force microscope-based single-molecule force spectroscopy of RNA unfolding.

Heus HA, Puchner EM, van Vugt-Jonker AJ, Zimmermann JL, Gaub HE.

Anal Biochem. 2011 Jul 1;414(1):1-6. doi: 10.1016/j.ab.2011.03.012. Epub 2011 Mar 12.

PMID:
21402049
18.

Functional analysis of the SRV-1 RNA frameshifting pseudoknot.

Olsthoorn RC, Reumerman R, Hilbers CW, Pleij CW, Heus HA.

Nucleic Acids Res. 2010 Nov;38(21):7665-72. doi: 10.1093/nar/gkq629. Epub 2010 Jul 17.

19.

1H and 13C resonance assignments of a guanine sensing riboswitch's terminator hairpin.

Ottink OM, Westerweele IM, Tesssari M, Nelissen FH, Heus HA, Wijmenga SS.

Biomol NMR Assign. 2010 Apr;4(1):89-91. doi: 10.1007/s12104-010-9215-z. Epub 2010 Mar 6.

20.

Enzymatic stereospecific preparation of fluorescent S-adenosyl-L-methionine analogs.

Ottink OM, Nelissen FH, Derks Y, Wijmenga SS, Heus HA.

Anal Biochem. 2010 Jan 15;396(2):280-3. doi: 10.1016/j.ab.2009.09.013. Epub 2009 Sep 11.

PMID:
19748477
21.

Preparation of selective and segmentally labeled single-stranded DNA for NMR by self-primed PCR and asymmetrical endonuclease double digestion.

Nelissen FH, Girard FC, Tessari M, Heus HA, Wijmenga SS.

Nucleic Acids Res. 2009 Sep;37(17):e114. doi: 10.1093/nar/gkp540. Epub 2009 Jun 24.

22.

The structure-function relationship of the enterovirus 3'-UTR.

Zoll J, Heus HA, van Kuppeveld FJ, Melchers WJ.

Virus Res. 2009 Feb;139(2):209-16. doi: 10.1016/j.virusres.2008.07.014. Epub 2008 Aug 30. Review.

PMID:
18706945
23.

Multiple segmental and selective isotope labeling of large RNA for NMR structural studies.

Nelissen FH, van Gammeren AJ, Tessari M, Girard FC, Heus HA, Wijmenga SS.

Nucleic Acids Res. 2008 Aug;36(14):e89. doi: 10.1093/nar/gkn397. Epub 2008 Jun 26.

24.

Cartilage-hair hypoplasia-associated mutations in the RNase MRP P3 domain affect RNA folding and ribonucleoprotein assembly.

Welting TJ, Mattijssen S, Peters FM, van Doorn NL, Dekkers L, van Venrooij WJ, Heus HA, Bonafé L, Pruijn GJ.

Biochim Biophys Acta. 2008 Mar;1783(3):455-66. doi: 10.1016/j.bbamcr.2007.11.016. Epub 2007 Dec 8.

25.

Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined induced fit mechanism.

Ottink OM, Rampersad SM, Tessari M, Zaman GJ, Heus HA, Wijmenga SS.

RNA. 2007 Dec;13(12):2202-12. Epub 2007 Oct 24.

26.

Nonspecific protein adsorption at the single molecule level studied by atomic force microscopy.

Schön P, Görlich M, Coenen MJ, Heus HA, Speller S.

Langmuir. 2007 Sep 25;23(20):9921-3. Epub 2007 Aug 21.

PMID:
17711309
27.

Breaking pseudo-twofold symmetry in the poliovirus 3'-UTR Y-stem by restoring Watson-Crick base pairs.

Zoll J, Tessari M, Van Kuppeveld FJ, Melchers WJ, Heus HA.

RNA. 2007 May;13(5):781-92.

28.

Macroscopic hierarchical surface patterning of porphyrin trimers via self-assembly and dewetting.

van Hameren R, Schön P, van Buul AM, Hoogboom J, Lazarenko SV, Gerritsen JW, Engelkamp H, Christianen PC, Heus HA, Maan JC, Rasing T, Speller S, Rowan AE, Elemans JA, Nolte RJ.

Science. 2006 Dec 1;314(5804):1433-6.

29.

An RNA conformational shift in recent H5N1 influenza A viruses.

Gultyaev AP, Heus HA, Olsthoorn RC.

Bioinformatics. 2007 Feb 1;23(3):272-6. Epub 2006 Nov 7.

PMID:
17090581
30.

Chemical synthesis of picornaviral protein primers of RNA replication.

Kriek NM, Meeuwenoord NJ, van den Elst H, Heus HA, van der Marel GA, Filippov DV.

Org Biomol Chem. 2006 Oct 7;4(19):3576-86. Epub 2006 Aug 30.

PMID:
16990933
31.

A GCUA tetranucleotide loop found in the poliovirus oriL by in vivo SELEX (un)expectedly forms a YNMG-like structure: Extending the YNMG family with GYYA.

Melchers WJ, Zoll J, Tessari M, Bakhmutov DV, Gmyl AP, Agol VI, Heus HA.

RNA. 2006 Sep;12(9):1671-82. Epub 2006 Aug 7.

32.

Structural and functional integrity of the coxsackievirus B3 oriR: spacing between coaxial RNA helices.

van Ooij MJ, Glaudemans DH, Heus HA, van Kuppeveld FJ, Melchers WJ.

J Gen Virol. 2006 Mar;87(Pt 3):689-95.

PMID:
16476992
33.

High similarity sequence comparison in clustering large sequence databases.

Dudoignon L, Glemet E, Heus HC, Raffinot M.

Proc IEEE Comput Soc Bioinform Conf. 2002;1:228-36.

PMID:
15838139
34.

Novel application of sRNA: stimulation of ribosomal frameshifting.

Olsthoorn RC, Laurs M, Sohet F, Hilbers CW, Heus HA, Pleij CW.

RNA. 2004 Nov;10(11):1702-3.

35.

Structures of non-canonical tandem base pairs in RNA helices: review.

Heus HA, Hilbers CW.

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):559-71. Review.

PMID:
14565230
36.
37.

Inactivation of the EGF-TM7 receptor EMR4 after the Pan-Homo divergence.

Hamann J, Kwakkenbos MJ, de Jong EC, Heus H, Olsen AS, van Lier RA.

Eur J Immunol. 2003 May;33(5):1365-71.

38.

Patent searches for genetic sequences: how to retrieve relevant records from patented sequence databases.

Dufresne G, Takács L, Heus HC, Codani JJ, Duval M.

Nat Biotechnol. 2002 Dec;20(12):1269-71. No abstract available.

PMID:
12454675
39.

Solution structure of the pseudoknot of SRV-1 RNA, involved in ribosomal frameshifting.

Michiels PJ, Versleijen AA, Verlaan PW, Pleij CW, Hilbers CW, Heus HA.

J Mol Biol. 2001 Jul 27;310(5):1109-23.

PMID:
11501999
40.

Hemimelic extra toes and Hammer toe are distinct mutations that show a genetic interaction.

Heus HC, Luijsterburg AJ, van Baren MJ, Breedveld GJ, Joosse MN, Nieuwenhuizen IM, Vermeij-Keers C, Oostra BA, Heutink P.

Mamm Genome. 2001 Jan;12(1):77-9. No abstract available.

PMID:
11178748
41.

Structure of the ribozyme substrate hairpin of Neurospora VS RNA: a close look at the cleavage site.

Michiels PJ, Schouten CH, Hilbers CW, Heus HA.

RNA. 2000 Dec;6(12):1821-32.

42.

Solution structure of a HNA-RNA hybrid.

Lescrinier E, Esnouf R, Schraml J, Busson R, Heus H, Hilbers C, Herdewijn P.

Chem Biol. 2000 Sep;7(9):719-31.

43.

New developments in structure determination of pseudoknots.

Hilbers CW, Michiels PJ, Heus HA.

Biopolymers. 1998;48(2-3):137-53. Review.

PMID:
10333742
44.

A physical and transcriptional map of the preaxial polydactyly locus on chromosome 7q36.

Heus HC, Hing A, van Baren MJ, Joosse M, Breedveld GJ, Wang JC, Burgess A, Donnis-Keller H, Berglund C, Zguricas J, Scherer SW, Rommens JM, Oostra BA, Heutink P.

Genomics. 1999 May 1;57(3):342-51.

PMID:
10329000
45.

Clinical and genetic studies on 12 preaxial polydactyly families and refinement of the localisation of the gene responsible to a 1.9 cM region on chromosome 7q36.

Zguricas J, Heus H, Morales-Peralta E, Breedveld G, Kuyt B, Mumcu EF, Bakker W, Akarsu N, Kay SP, Hovius SE, Heredero-Baute L, Oostra BA, Heutink P.

J Med Genet. 1999 Jan;36(1):32-40.

46.

Structure of the 3'-hairpin of the TYMV pseudoknot: preformation in RNA folding.

Kolk MH, van der Graaf M, Fransen CT, Wijmenga SS, Pleij CW, Heus HA, Hilbers CW.

EMBO J. 1998 Dec 15;17(24):7498-504.

47.

NMR structure of a classical pseudoknot: interplay of single- and double-stranded RNA.

Kolk MH, van der Graaf M, Wijmenga SS, Pleij CW, Heus HA, Hilbers CW.

Science. 1998 Apr 17;280(5362):434-8.

48.

Genetics of limb development and congenital hand malformations.

Zguricas J, Bakker WF, Heus H, Lindhout D, Heutink P, Hovius SE.

Plast Reconstr Surg. 1998 Apr;101(4):1126-35. Review.

PMID:
9514351
49.

The detailed structure of tandem G.A mismatched base-pair motifs in RNA duplexes is context dependent.

Heus HA, Wijmenga SS, Hoppe H, Hilbers CW.

J Mol Biol. 1997 Aug 8;271(1):147-58.

PMID:
9300061
50.

RNA aptamers.

Heus HA.

Nat Struct Biol. 1997 Aug;4(8):597-600. No abstract available.

PMID:
9253403

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