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Items: 7


Noninvasive Detection of Bladder Cancer by Shallow-Depth Genome-Wide Bisulfite Sequencing of Urinary Cell-Free DNA for Methylation and Copy Number Profiling.

Cheng THT, Jiang P, Teoh JYC, Heung MMS, Tam JCW, Sun X, Lee WS, Ni M, Chan RCK, Ng CF, Chan KCA, Chiu RWK, Lo YMD.

Clin Chem. 2019 Jul;65(7):927-936. doi: 10.1373/clinchem.2018.301341. Epub 2019 Apr 15.


Preferred end coordinates and somatic variants as signatures of circulating tumor DNA associated with hepatocellular carcinoma.

Jiang P, Sun K, Tong YK, Cheng SH, Cheng THT, Heung MMS, Wong J, Wong VWS, Chan HLY, Chan KCA, Lo YMD, Chiu RWK.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10925-E10933. doi: 10.1073/pnas.1814616115. Epub 2018 Oct 29.


Maternal plasma fetal DNA fractions in pregnancies with low and high risks for fetal chromosomal aneuploidies.

Hudecova I, Sahota D, Heung MM, Jin Y, Lee WS, Leung TY, Lo YM, Chiu RW.

PLoS One. 2014 Feb 28;9(2):e88484. doi: 10.1371/journal.pone.0088484. eCollection 2014.


Placenta-derived fetal specific mRNA is more readily detectable in maternal plasma than in whole blood.

Heung MM, Jin S, Tsui NB, Ding C, Leung TY, Lau TK, Chiu RW, Lo YM.

PLoS One. 2009 Jun 10;4(6):e5858. doi: 10.1371/journal.pone.0005858.


Development of extraction protocols to improve the yield for fetal RNA in maternal plasma.

Heung MM, Tsui NB, Leung TY, Lau TK, Lo YM, Chiu RW.

Prenat Diagn. 2009 Mar;29(3):277-9. doi: 10.1002/pd.2191. No abstract available.


Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection.

Lo YM, Tsui NB, Chiu RW, Lau TK, Leung TN, Heung MM, Gerovassili A, Jin Y, Nicolaides KH, Cantor CR, Ding C.

Nat Med. 2007 Feb;13(2):218-23. Epub 2007 Jan 7.


Genome-wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray.

Wong YF, Cheung TH, Tsao GS, Lo KW, Yim SF, Wang VW, Heung MM, Chan SC, Chan LK, Ho TW, Wong KW, Li C, Guo Y, Chung TK, Smith DI.

Int J Cancer. 2006 May 15;118(10):2461-9.

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