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Items: 44

1.

Interactions between stress and physical activity on Alzheimer's disease pathology.

Yuede CM, Timson BF, Hettinger JC, Yuede KM, Edwards HM, Lawson JE, Zimmerman SD, Cirrito JR.

Neurobiol Stress. 2018 Feb 22;8:158-171. doi: 10.1016/j.ynstr.2018.02.004. eCollection 2018 Feb. Review.

2.

AMPA-ergic regulation of amyloid-β levels in an Alzheimer's disease mouse model.

Hettinger JC, Lee H, Bu G, Holtzman DM, Cirrito JR.

Mol Neurodegener. 2018 May 15;13(1):22. doi: 10.1186/s13024-018-0256-6.

3.

RNAi-mediated reduction of hepatic Tmprss6 diminishes anemia and secondary iron overload in a splenectomized mouse model of β-thalassemia intermedia.

Schmidt PJ, Liu K, Visner G, Fitzgerald K, Fishman S, Racie T, Hettinger JL, Butler JS, Fleming MD.

Am J Hematol. 2018 Jun;93(6):745-750. doi: 10.1002/ajh.25079. Epub 2018 Mar 23.

4.

Silver Oxide Coatings with High Silver-Ion Elution Rates and Characterization of Bactericidal Activity.

Goderecci SS, Kaiser E, Yanakas M, Norris Z, Scaturro J, Oszust R, Medina CD, Waechter F, Heon M, Krchnavek RR, Yu L, Lofland SE, Demarest RM, Caputo GA, Hettinger JD.

Molecules. 2017 Sep 7;22(9). pii: E1487. doi: 10.3390/molecules22091487.

5.

Real-world experience with the all-oral, interferon-free regimen of ombitasvir/paritaprevir/ritonavir and dasabuvir for the treatment of chronic hepatitis C virus infection in the German Hepatitis C Registry.

Welzel TM, Hinrichsen H, Sarrazin C, Buggisch P, Baumgarten A, Christensen S, Berg T, Mauss S, Teuber G, Stein K, Deterding K, van Bömmel F, Heyne R, John C, Zimmermann T, Lutz T, Schott E, Hettinger J, Kleine H, König B, Hüppe D, Wedemeyer H.

J Viral Hepat. 2017 Oct;24(10):840-849. doi: 10.1111/jvh.12708. Epub 2017 May 25.

PMID:
28342229
6.

An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria.

Liebow A, Li X, Racie T, Hettinger J, Bettencourt BR, Najafian N, Haslett P, Fitzgerald K, Holmes RP, Erbe D, Querbes W, Knight J.

J Am Soc Nephrol. 2017 Feb;28(2):494-503. doi: 10.1681/ASN.2016030338. Epub 2016 Jul 18.

7.

Bad Ac-etylated Tau.

Hettinger JC, Cirrito JR.

Neuron. 2016 Apr 20;90(2):205-6. doi: 10.1016/j.neuron.2016.04.008.

8.

Rapid in vivo measurement of β-amyloid reveals biphasic clearance kinetics in an Alzheimer's mouse model.

Yuede CM, Lee H, Restivo JL, Davis TA, Hettinger JC, Wallace CE, Young KL, Hayne MR, Bu G, Li CZ, Cirrito JR.

J Exp Med. 2016 May 2;213(5):677-85. doi: 10.1084/jem.20151428. Epub 2016 Apr 11.

9.

Transcription Factor 7 Limits Regulatory T Cell Generation in the Thymus.

Barra MM, Richards DM, Hansson J, Hofer AC, Delacher M, Hettinger J, Krijgsveld J, Feuerer M.

J Immunol. 2015 Oct 1;195(7):3058-70. doi: 10.4049/jimmunol.1500821. Epub 2015 Aug 31.

10.

An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia.

Sehgal A, Barros S, Ivanciu L, Cooley B, Qin J, Racie T, Hettinger J, Carioto M, Jiang Y, Brodsky J, Prabhala H, Zhang X, Attarwala H, Hutabarat R, Foster D, Milstein S, Charisse K, Kuchimanchi S, Maier MA, Nechev L, Kandasamy P, Kel'in AV, Nair JK, Rajeev KG, Manoharan M, Meyers R, Sorensen B, Simon AR, Dargaud Y, Negrier C, Camire RM, Akinc A.

Nat Med. 2015 May;21(5):492-7. doi: 10.1038/nm.3847. Epub 2015 Apr 13.

PMID:
25849132
11.

Unbalanced translocations involving chromosome region 10q25.3q26.3 in patients with intellectual disability and complex phenotypes.

Hryshchenko NV, Bychkova GM, Tavokina LV, Brovko AO, Graziano C, Soloviov OO, Hettinger JA, Patsalis PC, Lurie IW, Livshits LA.

Cytogenet Genome Res. 2014;144(3):169-77. doi: 10.1159/000370086. Epub 2015 Jan 8.

PMID:
25573336
12.

Reply to comment on "An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice".

Sheline YI, West T, Yarasheski K, Jasielec MS, Hettinger JC, Tripoli DL, Xiong C, Frederiksen C, Grzelak MV, Bateman RJ, Morris JC, Lee JM, Cirrito JR.

Sci Transl Med. 2014 Dec 24;6(268):268lr4. doi: 10.1126/scitranslmed.3010609. No abstract available.

13.

Designing silk-silk protein alloy materials for biomedical applications.

Hu X, Duki S, Forys J, Hettinger J, Buchicchio J, Dobbins T, Yang C.

J Vis Exp. 2014 Aug 13;(90):e50891. doi: 10.3791/50891.

14.

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.

Dong Y, Love KT, Dorkin JR, Sirirungruang S, Zhang Y, Chen D, Bogorad RL, Yin H, Chen Y, Vegas AJ, Alabi CA, Sahay G, Olejnik KT, Wang W, Schroeder A, Lytton-Jean AK, Siegwart DJ, Akinc A, Barnes C, Barros SA, Carioto M, Fitzgerald K, Hettinger J, Kumar V, Novobrantseva TI, Qin J, Querbes W, Koteliansky V, Langer R, Anderson DG.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):3955-60. doi: 10.1073/pnas.1322937111. Epub 2014 Feb 10. Erratum in: Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5753.

15.

Functional analysis of MSH2 unclassified variants found in suspected Lynch syndrome patients reveals pathogenicity due to attenuated mismatch repair.

Wielders EA, Hettinger J, Dekker R, Kets CM, Ligtenberg MJ, Mensenkamp AR, van den Ouweland AM, Prins J, Wagner A, Dinjens WN, Dubbink HJ, van Hest LP, Menko F, Hogervorst F, Verhoef S, te Riele H.

J Med Genet. 2014 Apr;51(4):245-53. doi: 10.1136/jmedgenet-2013-101987. Epub 2014 Feb 5.

PMID:
24501230
16.

Origin of monocytes and macrophages in a committed progenitor.

Hettinger J, Richards DM, Hansson J, Barra MM, Joschko AC, Krijgsveld J, Feuerer M.

Nat Immunol. 2013 Aug;14(8):821-30. doi: 10.1038/ni.2638. Epub 2013 Jun 30.

PMID:
23812096
17.

Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics.

Maier MA, Jayaraman M, Matsuda S, Liu J, Barros S, Querbes W, Tam YK, Ansell SM, Kumar V, Qin J, Zhang X, Wang Q, Panesar S, Hutabarat R, Carioto M, Hettinger J, Kandasamy P, Butler D, Rajeev KG, Pang B, Charisse K, Fitzgerald K, Mui BL, Du X, Cullis P, Madden TD, Hope MJ, Manoharan M, Akinc A.

Mol Ther. 2013 Aug;21(8):1570-8. doi: 10.1038/mt.2013.124. Epub 2013 Jun 25.

18.

Keratinocyte-specific deletion of the receptor RAGE modulates the kinetics of skin inflammation in vivo.

Leibold JS, Riehl A, Hettinger J, Durben M, Hess J, Angel P.

J Invest Dermatol. 2013 Oct;133(10):2400-2406. doi: 10.1038/jid.2013.185. Epub 2013 Apr 17.

19.

An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia.

Schmidt PJ, Toudjarska I, Sendamarai AK, Racie T, Milstein S, Bettencourt BR, Hettinger J, Bumcrot D, Fleming MD.

Blood. 2013 Feb 14;121(7):1200-8. doi: 10.1182/blood-2012-09-453977. Epub 2012 Dec 6.

20.

Monocytes and macrophages in cancer: development and functions.

Richards DM, Hettinger J, Feuerer M.

Cancer Microenviron. 2013 Aug;6(2):179-91. doi: 10.1007/s12307-012-0123-x. Epub 2012 Nov 24.

21.

Harnessing a physiologic mechanism for siRNA delivery with mimetic lipoprotein particles.

Nakayama T, Butler JS, Sehgal A, Severgnini M, Racie T, Sharman J, Ding F, Morskaya SS, Brodsky J, Tchangov L, Kosovrasti V, Meys M, Nechev L, Wang G, Peng CG, Fang Y, Maier M, Rajeev KG, Li R, Hettinger J, Barros S, Clausen V, Zhang X, Wang Q, Hutabarat R, Dokholyan NV, Wolfrum C, Manoharan M, Kotelianski V, Stoffel M, Sah DW.

Mol Ther. 2012 Aug;20(8):1582-9. doi: 10.1038/mt.2012.33. Epub 2012 Jun 5.

22.

DRD2 and PPP1R1B (DARPP-32) polymorphisms independently confer increased risk for autism spectrum disorders and additively predict affected status in male-only affected sib-pair families.

Hettinger JA, Liu X, Hudson ML, Lee A, Cohen IL, Michaelis RC, Schwartz CE, Lewis SM, Holden JJ.

Behav Brain Funct. 2012 May 4;8:19. doi: 10.1186/1744-9081-8-19.

23.

De novo 5q35.5 duplication with clinical presentation of Sotos syndrome.

Kasnauskiene J, Cimbalistiene L, Ciuladaite Z, Preiksaitiene E, Kučinskienė ZA, Hettinger JA, Sismani C, Patsalis PC, Kučinskas V.

Am J Med Genet A. 2011 Oct;155A(10):2501-7.

PMID:
21998857
24.

p66(shc)'s role as an essential mitophagic molecule in controlling neuronal redox and energetic tone.

Kleman AM, Brown JE, Zeiger SL, Hettinger JC, Brooks JD, Holt B, Morrow JD, Musiek ES, Milne GL, McLaughlin B.

Autophagy. 2010 Oct;6(7):948-9. doi: 10.1523/j.neurosci.6366-09.2010. Epub 2010 Oct 14.

25.

Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning.

Brown JE, Zeiger SL, Hettinger JC, Brooks JD, Holt B, Morrow JD, Musiek ES, Milne G, McLaughlin B.

J Neurosci. 2010 Apr 14;30(15):5242-52. doi: 10.1523/JNEUROSCI.6366-09.2010.

26.

A DRD1 haplotype is associated with risk for autism spectrum disorders in male-only affected sib-pair families.

Hettinger JA, Liu X, Schwartz CE, Michaelis RC, Holden JJ.

Am J Med Genet B Neuropsychiatr Genet. 2008 Jul 5;147B(5):628-36. doi: 10.1002/ajmg.b.30655.

PMID:
18205172
27.

The G22A polymorphism of the ADA gene and susceptibility to autism spectrum disorders.

Hettinger JA, Liu X, Holden JJ.

J Autism Dev Disord. 2008 Jan;38(1):14-9. Epub 2007 Mar 6.

PMID:
17340203
28.

In vivo three-dimensional imaging of plants with optical coherence microscopy.

Reeves A, Parsons RL, Hettinger JW, Medford JI.

J Microsc. 2002 Dec;208(Pt 3):177-89.

29.

A novel arginine vasopressin-neurophysin II mutation causes autosomal dominant neurohypophyseal diabetes insipidus and morphologic pituitary changes.

Skordis N, Patsalis PC, Hettinger JA, Kontou M, Herakleous E, Krishnamani MR, Phillips JA 3rd.

Horm Res. 2000;53(5):239-45.

PMID:
11150885
30.

Optical coherence microscopy. A technology for rapid, in vivo, non-destructive visualization of plants and plant cells.

Hettinger JW, de la Peña Mattozzi M, Myers WR, Williams ME, Reeves A, Parsons RL, Haskell RC, Petersen DC, Wang R, Medford JI.

Plant Physiol. 2000 May;123(1):3-16.

31.

Genetic variation and intergenerational FMR1 CGG-repeat stability in 100 unrelated three-generation families from the normal population.

Patsalis PC, Sismani C, Stylianou S, Ioannou P, Joseph G, Manoli P, Holden JJ, Hettinger JA.

Am J Med Genet. 1999 May 28;84(3):217-20.

PMID:
10331595
32.

Frequencies of "grey-zone" and premutation-size FMR1 CGG-repeat alleles in patients with developmental disability in Cyprus and Canada.

Patsalis PC, Sismani C, Hettinger JA, Holden JJ, Lawson JS, Chalifoux M, Wing M, Walker M, Leggo J.

Am J Med Genet. 1999 May 28;84(3):195-7. No abstract available.

PMID:
10331589
33.

Molecular screening of fragile X (FRAXA) and FRAXE mental retardation syndromes in the Hellenic population of Greece and Cyprus: incidence, genetic variation, and stability.

Patsalis PC, Sismani C, Hettinger JA, Boumba I, Georgiou I, Stylianidou G, Anastasiadou V, Koukoulli R, Pagoulatos G, Syrrou M.

Am J Med Genet. 1999 May 28;84(3):184-90.

PMID:
10331587
34.

FMR1 repeat analysis in patients with ovarian dysfunction or failure.

Patsalis PC, Hettinger JA, Sismani C.

Am J Med Genet. 1999 Apr 2;83(4):329-30. No abstract available. Erratum in: Am J Med Genet 1999 Sep 17;86(3):304.

PMID:
10208173
35.

Unusual Vortex Dynamics in Nb-a-Si Multilayers with Strong Interlayer Coupling.

Hettinger JD, Washburn BR, Remmes NB, Steel DG, Gray KE, Fullerton EE, Sowers CH.

Phys Rev Lett. 1996 Dec 23;77(26):5280-5283. No abstract available.

PMID:
10062761
36.

Interaction of two-dimensional vortices with linear ion tracks in the highly anisotropic layered cuprates.

Gray KE, Hettinger JD, Miller DJ, Washburn BR, Moreau C, Lee C, Glagola BG, Eddy MM.

Phys Rev B Condens Matter. 1996 Aug 1;54(5):3622-3627. No abstract available.

PMID:
9986269
37.

Pinning strength dependence of mixed-state Hall effect in YBa2Cu3O7 crystals with columnar defects.

Kang WN, Kim DH, Shim SY, Park JH, Hahn TS, Choi SS, Lee WC, Hettinger JD, Gray KE, Glagola B.

Phys Rev Lett. 1996 Apr 15;76(16):2993-2996. No abstract available.

PMID:
10060843
38.

Comparison of superconducting flux pinning due to ion irradiation and fishtail effects.

Xu M, Ostenson JE, Finnemore DK, Kramer MJ, Fendrich JA, Hettinger JD, Welp U, Crabtree GW, Dabrowski B, Zhang K.

Phys Rev B Condens Matter. 1996 Mar 1;53(9):5815-5817. No abstract available.

PMID:
9984187
39.

Measurement of the intrinsic Josephson coupling energy between Cu-O bilayers in a High-Tc superconductor: Possibility of an unusual electron transmission rate.

Hettinger JD, Gray KE, Veal BW, Paulikas AP, Kostic P, Washburn BR, Tonjes WC, Flewelling AC.

Phys Rev Lett. 1995 Jun 5;74(23):4726-4729. No abstract available.

PMID:
10058583
40.

Tunneling and hopping conduction in Langmuir-Blodgett thin films of poly(3-hexylthiophene).

Punkka E, Rubner MF, Hettinger JD, Brooks JS, Hannahs ST.

Phys Rev B Condens Matter. 1991 Apr 15;43(11):9076-9086. No abstract available.

PMID:
9996576
41.

Flux creep and high-field critical currents in epitaxial thin films of YBa2Cu3O7.

Hettinger JD, Swanson AG, Skocpol WJ, Brooks JS, Graybeal JM, Mankiewich PM, Howard RE, Straughn BL, Burkhardt EG.

Phys Rev Lett. 1989 Apr 24;62(17):2044-2047. No abstract available.

PMID:
10039842
42.

Psychometric telepathy across the Atlantic.

HETTINGER JH.

Adv Sci. 1948 Jul;5(18):140. No abstract available.

PMID:
18875240
43.

A program for the investigation of psychometry.

HETTINGER J.

J Parapsychol. 1948 Jun;12(2):90-5. No abstract available.

PMID:
18867093
44.

Psychometric telepathy across the Atlantic.

HETTINGER J.

J Am Soc Psych Res. 1947 Jul;41(3):94-122. No abstract available.

PMID:
20254708

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