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Items: 38

1.

All optical control of comb-like coherent acoustic phonons in multiple quantum well structures through double-pump-pulse pump-probe experiments.

Li C, Gusev V, Dekorsy T, Hettich M.

Opt Express. 2019 Jun 24;27(13):18706-18730. doi: 10.1364/OE.27.018706.

PMID:
31252809
2.

Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.

Claus C, Ferrara C, Xu W, Sam J, Lang S, Uhlenbrock F, Albrecht R, Herter S, Schlenker R, Hüsser T, Diggelmann S, Challier J, Mössner E, Hosse RJ, Hofer T, Brünker P, Joseph C, Benz J, Ringler P, Stahlberg H, Lauer M, Perro M, Chen S, Küttel C, Bhavani Mohan PL, Nicolini V, Birk MC, Ongaro A, Prince C, Gianotti R, Dugan G, Whitlow CT, Solingapuram Sai KK, Caudell DL, Burgos-Rodriguez AG, Cline JM, Hettich M, Ceppi M, Giusti AM, Crameri F, Driessen W, Morcos PN, Freimoser-Grundschober A, Levitsky V, Amann M, Grau-Richards S, von Hirschheydt T, Tournaviti S, Mølhøj M, Fauti T, Heinzelmann-Schwarz V, Teichgräber V, Colombetti S, Bacac M, Zippelius A, Klein C, Umaña P.

Sci Transl Med. 2019 Jun 12;11(496). pii: eaav5989. doi: 10.1126/scitranslmed.aav5989.

PMID:
31189721
3.

Combination treatment with hypofractionated radiotherapy plus IL-2/anti-IL-2 complexes and its theranostic evaluation.

Jing H, Hettich M, Gaedicke S, Firat E, Bartholomä M, Niedermann G.

J Immunother Cancer. 2019 Feb 26;7(1):55. doi: 10.1186/s40425-019-0537-9.

4.

High-Pressure Effect on the Optical Extinction of a Single Gold Nanoparticle.

Medeghini F, Hettich M, Rouxel R, Silva Santos SD, Hermelin S, Pertreux E, Torres Dias A, Legrand F, Maioli P, Crut A, Vallée F, San Miguel A, Del Fatti N.

ACS Nano. 2018 Oct 23;12(10):10310-10316. doi: 10.1021/acsnano.8b05539. Epub 2018 Oct 9.

PMID:
30299926
5.

Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis.

Matthes F, Hettich MM, Schilling J, Flores-Dominguez D, Blank N, Wiglenda T, Buntru A, Wolf H, Weber S, Vorberg I, Dagane A, Dittmar G, Wanker E, Ehninger D, Krauss S.

Cell Death Discov. 2018 Jan 29;4:4. doi: 10.1038/s41420-017-0003-8. eCollection 2018 Dec.

6.

Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.

Prestipino A, Emhardt AJ, Aumann K, O'Sullivan D, Gorantla SP, Duquesne S, Melchinger W, Braun L, Vuckovic S, Boerries M, Busch H, Halbach S, Pennisi S, Poggio T, Apostolova P, Veratti P, Hettich M, Niedermann G, Bartholomä M, Shoumariyeh K, Jutzi JS, Wehrle J, Dierks C, Becker H, Schmitt-Graeff A, Follo M, Pfeifer D, Rohr J, Fuchs S, Ehl S, Hartl FA, Minguet S, Miething C, Heidel FH, Kröger N, Triviai I, Brummer T, Finke J, Illert AL, Ruggiero E, Bonini C, Duyster J, Pahl HL, Lane SW, Hill GR, Blazar BR, von Bubnoff N, Pearce EL, Zeiser R.

Sci Transl Med. 2018 Feb 21;10(429). pii: eaam7729. doi: 10.1126/scitranslmed.aam7729.

7.

Topological guiding of elastic waves in phononic metamaterials based on 2D pentamode structures.

Guo Y, Dekorsy T, Hettich M.

Sci Rep. 2017 Dec 22;7(1):18043. doi: 10.1038/s41598-017-18394-8.

8.

Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex.

Schweiger S, Matthes F, Posey K, Kickstein E, Weber S, Hettich MM, Pfurtscheller S, Ehninger D, Schneider R, Krauß S.

Sci Rep. 2017 Oct 23;7(1):13753. doi: 10.1038/s41598-017-12974-4.

9.

Interface Adhesion and Structural Characterization of Rolled-up GaAs/In0.2Ga0.8As Multilayer Tubes by Coherent Phonon Spectroscopy.

Brick D, Engemaier V, Guo Y, Grossmann M, Li G, Grimm D, Schmidt OG, Schubert M, Gusev VE, Hettich M, Dekorsy T.

Sci Rep. 2017 Jul 14;7(1):5385. doi: 10.1038/s41598-017-05739-6.

10.

High-speed asynchronous optical sampling based on GHz Yb:KYW oscillators.

Li C, Krauß N, Schäfer G, Ebner L, Kliebisch O, Schmidt J, Winnerl S, Hettich M, Dekorsy T.

Opt Express. 2017 Apr 17;25(8):9204-9212. doi: 10.1364/OE.25.009204.

PMID:
28437994
11.

Beyond checkpoint inhibition - Immunotherapeutical strategies in combination with radiation.

Eckert F, Gaipl US, Niedermann G, Hettich M, Schilbach K, Huber SM, Zips D.

Clin Transl Radiat Oncol. 2017 Feb 4;2:29-35. doi: 10.1016/j.ctro.2016.12.006. eCollection 2017 Feb. Review.

12.

Viscoelastic properties and efficient acoustic damping in confined polymer nano-layers at GHz frequencies.

Hettich M, Jacob K, Ristow O, Schubert M, Bruchhausen A, Gusev V, Dekorsy T.

Sci Rep. 2016 Sep 16;6:33471. doi: 10.1038/srep33471.

13.

High-Resolution PET Imaging with Therapeutic Antibody-based PD-1/PD-L1 Checkpoint Tracers.

Hettich M, Braun F, Bartholomä MD, Schirmbeck R, Niedermann G.

Theranostics. 2016 Jun 18;6(10):1629-40. doi: 10.7150/thno.15253. eCollection 2016.

14.

Checkpoint Antibodies but not T Cell-Recruiting Diabodies Effectively Synergize with TIL-Inducing γ-Irradiation.

Hettich M, Lahoti J, Prasad S, Niedermann G.

Cancer Res. 2016 Aug 15;76(16):4673-83. doi: 10.1158/0008-5472.CAN-15-3451. Epub 2016 Jun 14.

15.

Collective Modes and Structural Modulation in Ni-Mn-Ga(Co) Martensite Thin Films Probed by Femtosecond Spectroscopy and Scanning Tunneling Microscopy.

Schubert M, Schaefer H, Mayer J, Laptev A, Hettich M, Merklein M, He C, Rummel C, Ristow O, Großmann M, Luo Y, Gusev V, Samwer K, Fonin M, Dekorsy T, Demsar J.

Phys Rev Lett. 2015 Aug 14;115(7):076402. Epub 2015 Aug 13.

PMID:
26317735
16.

Limited effects of an eIF2αS51A allele on neurological impairments in the 5xFAD mouse model of Alzheimer's disease.

Paesler K, Xie K, Hettich MM, Siwek ME, Ryan DP, Schröder S, Papazoglou A, Broich K, Müller R, Trog A, Garthe A, Kempermann G, Weiergräber M, Ehninger D.

Neural Plast. 2015;2015:825157. doi: 10.1155/2015/825157. Epub 2015 Mar 26.

17.

Effective Eradication of Glioblastoma Stem Cells by Local Application of an AC133/CD133-Specific T-cell-Engaging Antibody and CD8 T Cells.

Prasad S, Gaedicke S, Machein M, Mittler G, Braun F, Hettich M, Firat E, Klingner K, Schüler J, Wider D, Wäsch RM, Herold-Mende C, Elsässer-Beile U, Niedermann G.

Cancer Res. 2015 Jun 1;75(11):2166-76. doi: 10.1158/0008-5472.CAN-14-2415. Epub 2015 Apr 3.

18.

Patient-derived glioblastoma stem cells are killed by CD133-specific CAR T cells but induce the T cell aging marker CD57.

Zhu X, Prasad S, Gaedicke S, Hettich M, Firat E, Niedermann G.

Oncotarget. 2015 Jan 1;6(1):171-84.

19.

The anti-diabetic drug metformin reduces BACE1 protein level by interfering with the MID1 complex.

Hettich MM, Matthes F, Ryan DP, Griesche N, Schröder S, Dorn S, Krauβ S, Ehninger D.

PLoS One. 2014 Jul 15;9(7):e102420. doi: 10.1371/journal.pone.0102420. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e107080.

20.

Metformin lowers Ser-129 phosphorylated α-synuclein levels via mTOR-dependent protein phosphatase 2A activation.

Pérez-Revuelta BI, Hettich MM, Ciociaro A, Rotermund C, Kahle PJ, Krauss S, Di Monte DA.

Cell Death Dis. 2014 May 8;5:e1209. doi: 10.1038/cddis.2014.175.

21.

Noninvasive positron emission tomography and fluorescence imaging of CD133+ tumor stem cells.

Gaedicke S, Braun F, Prasad S, Machein M, Firat E, Hettich M, Gudihal R, Zhu X, Klingner K, Schüler J, Herold-Mende CC, Grosu AL, Behe M, Weber W, Mäcke H, Niedermann G.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):E692-701. doi: 10.1073/pnas.1314189111. Epub 2014 Jan 27.

22.

Rapamycin extends murine lifespan but has limited effects on aging.

Neff F, Flores-Dominguez D, Ryan DP, Horsch M, Schröder S, Adler T, Afonso LC, Aguilar-Pimentel JA, Becker L, Garrett L, Hans W, Hettich MM, Holtmeier R, Hölter SM, Moreth K, Prehn C, Puk O, Rácz I, Rathkolb B, Rozman J, Naton B, Ordemann R, Adamski J, Beckers J, Bekeredjian R, Busch DH, Ehninger G, Graw J, Höfler H, Klingenspor M, Klopstock T, Ollert M, Stypmann J, Wolf E, Wurst W, Zimmer A, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Ehninger D.

J Clin Invest. 2013 Aug;123(8):3272-91. doi: 10.1172/JCI67674. Epub 2013 Jul 25.

23.

Lifetimes of confined acoustic phonons in ultrathin silicon membranes.

Cuffe J, Ristow O, Chávez E, Shchepetov A, Chapuis PO, Alzina F, Hettich M, Prunnila M, Ahopelto J, Dekorsy T, Sotomayor Torres CM.

Phys Rev Lett. 2013 Mar 1;110(9):095503. Epub 2013 Feb 26.

PMID:
23496722
24.

Adult-onset fluoxetine treatment does not improve behavioral impairments and may have adverse effects on the Ts65Dn mouse model of Down syndrome.

Heinen M, Hettich MM, Ryan DP, Schnell S, Paesler K, Ehninger D.

Neural Plast. 2012;2012:467251. doi: 10.1155/2012/467251. Epub 2012 Jul 16.

25.

Neuron-specific deletion of a single copy of the insulin-like growth factor-1 receptor gene reduces fat accumulation during aging.

Freude S, Schilbach K, Hettich MM, Brönneke HS, Zemva J, Krone W, Schubert M.

Horm Metab Res. 2012 Feb;44(2):99-104. doi: 10.1055/s-0031-1298018. Epub 2011 Dec 23.

PMID:
22198814
26.

Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease.

Stöhr O, Schilbach K, Moll L, Hettich MM, Freude S, Wunderlich FT, Ernst M, Zemva J, Brüning JC, Krone W, Udelhoven M, Schubert M.

Age (Dordr). 2013 Feb;35(1):83-101. doi: 10.1007/s11357-011-9333-2. Epub 2011 Nov 6.

27.

Role of WNT-5a in the determination of human mesenchymal stem cells into preadipocytes.

Bilkovski R, Schulte DM, Oberhauser F, Gomolka M, Udelhoven M, Hettich MM, Roth B, Heidenreich A, Gutschow C, Krone W, Laudes M.

J Biol Chem. 2010 Feb 26;285(9):6170-8. doi: 10.1074/jbc.M109.054338. Epub 2009 Dec 23.

28.

Identification of a region in the human IRS2 promoter essential for stress induced transcription depending on SP1, NFI binding and ERK activation in HepG2 cells.

Udelhoven M, Leeser U, Freude S, Hettich MM, Laudes M, Schnitker J, Krone W, Schubert M.

J Mol Endocrinol. 2010 Feb;44(2):99-113. doi: 10.1677/JME-08-0182. Epub 2009 Sep 15.

PMID:
19755487
29.

Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease.

Freude S, Hettich MM, Schumann C, Stöhr O, Koch L, Köhler C, Udelhoven M, Leeser U, Müller M, Kubota N, Kadowaki T, Krone W, Schröder H, Brüning JC, Schubert M.

FASEB J. 2009 Oct;23(10):3315-24. doi: 10.1096/fj.09-132043. Epub 2009 Jun 1.

PMID:
19487308
30.

IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination.

Freude S, Leeser U, Müller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Köhler C, Schröder H, Krone W, Brüning JC, Schubert M.

J Neurochem. 2008 Nov;107(4):907-17. doi: 10.1111/j.1471-4159.2008.05631.x. Epub 2008 Sep 18.

31.

Prescription and tolerability of meloxicam in day-to-day practice: postmarketing observational cohort study of 13,307 patients in Germany.

Zeidler H, Kaltwasser JP, Leonard JP, Kohlmann T, Sigmund R, Degner F, Hettich M.

J Clin Rheumatol. 2002 Dec;8(6):305-15.

PMID:
17041399
32.

Different activation patterns of proinflammatory cytokines in melancholic and non-melancholic major depression are associated with HPA axis activity.

Kaestner F, Hettich M, Peters M, Sibrowski W, Hetzel G, Ponath G, Arolt V, Cassens U, Rothermundt M.

J Affect Disord. 2005 Aug;87(2-3):305-11.

PMID:
15951024
33.

[The starting phase of a psychiatric unit--a statistical study].

Plenge T, Eilers M, Hettich M, Tölle R.

Psychiatr Prax. 2003 Mar;30(2):83-8. German.

PMID:
12601597
34.

A comparison of the efficacy and tolerability of meloxicam and diclofenac in the treatment of patients with osteoarthritis of the lumbar spine.

Valat JP, Accardo S, Reginster JY, Wouters M, Hettich M, Lieu PL; International Meloxicam Lumbar Osteoarthritis Group.

Inflamm Res. 2001 Mar;50 Suppl 1:S30-4.

PMID:
11339519
35.

[Selective cyclooxygenase-2 inhibitor].

Hettich M, Thomae K.

Internist (Berl). 1997 Oct;38(10):1007. German. No abstract available.

PMID:
9432492
38.

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