Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 21

1.

Cell Wall Hydrolytic Enzymes Enhance Antimicrobial Drug Activity Against Mycobacterium.

Gustine JN, Au MB, Haserick JR, Hett EC, Rubin EJ, Gibson FC 3rd, Deng LL.

Curr Microbiol. 2019 Apr;76(4):398-409. doi: 10.1007/s00284-018-1620-z. Epub 2019 Jan 2.

PMID:
30603964
2.

CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling.

Henry KL, Kellner D, Bajrami B, Anderson JE, Beyna M, Bhisetti G, Cameron T, Capacci AG, Bertolotti-Ciarlet A, Feng J, Gao B, Hopkins B, Jenkins T, Li K, May-Dracka T, Murugan P, Wei R, Zeng W, Allaire N, Buckler A, Loh C, Juhasz P, Lucas B, Ennis KA, Vollman E, Cahir-McFarland E, Hett EC, Ols ML.

Sci Signal. 2018 Jul 31;11(541). pii: eaam8216. doi: 10.1126/scisignal.aam8216.

PMID:
30065029
3.

Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue.

Fadeyi OO, Hoth LR, Choi C, Feng X, Gopalsamy A, Hett EC, Kyne RE Jr, Robinson RP, Jones LH.

ACS Chem Biol. 2017 Aug 18;12(8):2015-2020. doi: 10.1021/acschembio.7b00403. Epub 2017 Jul 20.

PMID:
28718624
4.

Selectivity Determination of a Small Molecule Chemical Probe Using Protein Microarray and Affinity Capture Techniques.

Hett EC, Kyne RE Jr, Gopalsamy A, Tones MA, Xu H, Thio GL, Nolan E, Jones LH.

ACS Comb Sci. 2016 Oct 10;18(10):611-615. Epub 2016 Aug 17.

PMID:
27494431
5.

Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells.

Xu H, Gopalsamy A, Hett EC, Salter S, Aulabaugh A, Kyne RE, Pierce B, Jones LH.

Org Biomol Chem. 2016 Jul 14;14(26):6179-83. doi: 10.1039/c6ob01078d. Epub 2016 May 24.

PMID:
27216142
6.

Know your target, know your molecule.

Bunnage ME, Gilbert AM, Jones LH, Hett EC.

Nat Chem Biol. 2015 Jun;11(6):368-72. doi: 10.1038/nchembio.1813. No abstract available.

PMID:
25978985
7.

A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS.

Xu H, Hett EC, Gopalsamy A, Parikh MD, Geoghegan KF, Kyne RE Jr, Menard CA, Narayanan A, Robinson RP, Johnson DS, Tones MA, Jones LH.

Mol Biosyst. 2015 Oct;11(10):2709-12. doi: 10.1039/c5mb00288e.

PMID:
25959423
8.

Rational targeting of active-site tyrosine residues using sulfonyl fluoride probes.

Hett EC, Xu H, Geoghegan KF, Gopalsamy A, Kyne RE Jr, Menard CA, Narayanan A, Parikh MD, Liu S, Roberts L, Robinson RP, Tones MA, Jones LH.

ACS Chem Biol. 2015 Apr 17;10(4):1094-8. doi: 10.1021/cb5009475. Epub 2015 Jan 29.

PMID:
25571984
9.

A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors.

Lanning BR, Whitby LR, Dix MM, Douhan J, Gilbert AM, Hett EC, Johnson TO, Joslyn C, Kath JC, Niessen S, Roberts LR, Schnute ME, Wang C, Hulce JJ, Wei B, Whiteley LO, Hayward MM, Cravatt BF.

Nat Chem Biol. 2014 Sep;10(9):760-767. doi: 10.1038/nchembio.1582. Epub 2014 Jul 13.

10.

Understanding and applying tyrosine biochemical diversity.

Jones LH, Narayanan A, Hett EC.

Mol Biosyst. 2014 May;10(5):952-69. doi: 10.1039/c4mb00018h. Review.

PMID:
24623162
11.

CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells.

Slater LH, Hett EC, Clatworthy AE, Mark KG, Hung DT.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7. doi: 10.1073/pnas.1302257110. Epub 2013 May 28.

12.

Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.

Hett EC, Slater LH, Mark KG, Kawate T, Monks BG, Stutz A, Latz E, Hung DT.

Nat Chem Biol. 2013 Jun;9(6):398-405. doi: 10.1038/nchembio.1236. Epub 2013 Apr 21. Erratum in: Nat Chem Biol. 2013 Jul;9(7):466.

13.

Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death.

Slater LH, Hett EC, Mark K, Chumbler NM, Patel D, Lacy DB, Collier RJ, Hung DT.

ACS Chem Biol. 2013 Apr 19;8(4):812-22. doi: 10.1021/cb300555n. Epub 2013 Feb 4.

14.

Interaction and modulation of two antagonistic cell wall enzymes of mycobacteria.

Hett EC, Chao MC, Rubin EJ.

PLoS Pathog. 2010 Jul 29;6(7):e1001020. doi: 10.1371/journal.ppat.1001020.

15.

The ABC's of industry: a postdoc program provides a sneak peek into industry careers.

Abu-Yousif AO, Hett EC, Skoczenski AM, Hasan T.

Nat Biotechnol. 2010 Jun;28(6):625-6. doi: 10.1038/nbt0610-625. No abstract available.

PMID:
20531344
16.

Targeting multiple biofilm pathways.

Hett EC, Hung DT.

Chem Biol. 2009 Dec 24;16(12):1216-8. doi: 10.1016/j.chembiol.2009.12.003.

17.

A mycobacterial enzyme essential for cell division synergizes with resuscitation-promoting factor.

Hett EC, Chao MC, Deng LL, Rubin EJ.

PLoS Pathog. 2008 Feb 29;4(2):e1000001. doi: 10.1371/journal.ppat.1000001.

18.

Bacterial growth and cell division: a mycobacterial perspective.

Hett EC, Rubin EJ.

Microbiol Mol Biol Rev. 2008 Mar;72(1):126-56, table of contents. doi: 10.1128/MMBR.00028-07. Review.

19.

Mycobacterium tuberculosis Rv2224c modulates innate immune responses.

Rengarajan J, Murphy E, Park A, Krone CL, Hett EC, Bloom BR, Glimcher LH, Rubin EJ.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):264-9. doi: 10.1073/pnas.0710601105. Epub 2008 Jan 2.

20.

A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis.

Hett EC, Chao MC, Steyn AJ, Fortune SM, Deng LL, Rubin EJ.

Mol Microbiol. 2007 Nov;66(3):658-68. Epub 2007 Oct 4.

21.

Invasive group A streptococcal infections in the San Francisco Bay area, 1989-99.

Passaro DJ, Smitht DS, Hett EC, Reingold AL, Daily P, van Beneden CA, Vugia DJ.

Epidemiol Infect. 2002 Dec;129(3):471-8.

Supplemental Content

Support Center