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Differential excitatory vs inhibitory SCN expression at single cell level regulates brain sodium channel function in neurodevelopmental disorders.

Du J, Simmons S, Brunklaus A, Adiconis X, Hession CC, Fu Z, Li Y, Shema R, Møller RS, Barak B, Feng G, Meisler M, Sanders S, Lerche H, Campbell AJ, McCarroll S, Levin JZ, Lal D.

Eur J Paediatr Neurol. 2019 Dec 28. pii: S1090-3798(19)30439-8. doi: 10.1016/j.ejpn.2019.12.019. [Epub ahead of print]


The Impact of Equine Therapy and an Audio-Visual Approach Emphasizing Rhythm and Beat Perception in Children with Developmental Coordination Disorder.

Hession CE, Law Smith MJ, Watterson D, Oxley N, Murphy BA.

J Altern Complement Med. 2019 May;25(5):535-541. doi: 10.1089/acm.2017.0242. Epub 2019 Feb 21.


Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons.

Tekin H, Simmons S, Cummings B, Gao L, Adiconis X, Hession CC, Ghoshal A, Dionne D, Choudhury SR, Yesilyurt V, Sanjana NE, Shi X, Lu C, Heidenreich M, Pan JQ, Levin JZ, Zhang F.

Nat Biomed Eng. 2018 Jul;2(7):540-554. doi: 10.1038/s41551-018-0219-9. Epub 2018 Apr 9.


Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction.

Lin EYS, Silvian LF, Marcotte DJ, Banos CC, Jow F, Chan TR, Arduini RM, Qian F, Baker DP, Bergeron C, Hession CA, Huganir RL, Borenstein CF, Enyedy I, Zou J, Rohde E, Wittmann M, Kumaravel G, Rhodes KJ, Scannevin RH, Dunah AW, Guckian KM.

Sci Rep. 2018 Sep 7;8(1):13438. doi: 10.1038/s41598-018-31680-3.


Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure.

Marcotte DJ, Hus JC, Banos CC, Wildes C, Arduini R, Bergeron C, Hession CA, Baker DP, Lin E, Guckian KM, Dunah AW, Silvian LF.

Protein Sci. 2018 Mar;27(3):672-680. doi: 10.1002/pro.3361. Epub 2018 Jan 30.


Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons.

Habib N, Li Y, Heidenreich M, Swiech L, Avraham-Davidi I, Trombetta JJ, Hession C, Zhang F, Regev A.

Science. 2016 Aug 26;353(6302):925-8. doi: 10.1126/science.aad7038. Epub 2016 Jul 28.


The use of real life activities in rehabilitation: the experience of young men with traumatic brain injuries from regional, rural and remote areas in Australia.

Sullivan CT, Gray MA, Williams GP, Green DJ, Hession CA.

J Rehabil Med. 2014 May;46(5):424-9. doi: 10.2340/16501977-1788.


Pillars article: A lymphotoxin-B-specific receptor. Science. 1994. 264: 707-710.

Crowe PD, Vanarsdale TL, Walter BN, Ware CF, Hession C, Ehrenfels B, Browning JL, Din WS, Goodwin RG, Smith CA.

J Immunol. 2014 Mar 1;192(5):2015-8. No abstract available.


Therapeutic horse riding improves cognition, mood arousal, and ambulation in children with dyspraxia.

Hession CE, Eastwood B, Watterson D, Lehane CM, Oxley N, Murphy BA.

J Altern Complement Med. 2014 Jan;20(1):19-23. doi: 10.1089/acm.2013.0207. Epub 2013 Oct 2.


Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism.

Marcotte D, Zeng W, Hus JC, McKenzie A, Hession C, Jin P, Bergeron C, Lugovskoy A, Enyedy I, Cuervo H, Wang D, Atmanene C, Roecklin D, Vecchi M, Vivat V, Kraemer J, Winkler D, Hong V, Chao J, Lukashev M, Silvian L.

Bioorg Med Chem. 2013 Jul 15;21(14):4011-9. doi: 10.1016/j.bmc.2013.04.019. Epub 2013 Apr 19.


Alcohol use: from childhood through adolescence.

Lewis TP, Hession C.

J Pediatr Nurs. 2012 Oct;27(5):e50-8. doi: 10.1016/j.pedn.2012.01.003. Epub 2012 Feb 10. Review.


Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery.

Erlanson DA, Arndt JW, Cancilla MT, Cao K, Elling RA, English N, Friedman J, Hansen SK, Hession C, Joseph I, Kumaravel G, Lee WC, Lind KE, McDowell RS, Miatkowski K, Nguyen C, Nguyen TB, Park S, Pathan N, Penny DM, Romanowski MJ, Scott D, Silvian L, Simmons RL, Tangonan BT, Yang W, Sun L.

Bioorg Med Chem Lett. 2011 May 15;21(10):3078-83. doi: 10.1016/j.bmcl.2011.03.032. Epub 2011 Mar 17.


Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases.

Marcotte DJ, Liu YT, Arduini RM, Hession CA, Miatkowski K, Wildes CP, Cullen PF, Hong V, Hopkins BT, Mertsching E, Jenkins TJ, Romanowski MJ, Baker DP, Silvian LF.

Protein Sci. 2010 Mar;19(3):429-39. doi: 10.1002/pro.321.


Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo.

Doern A, Cao X, Sereno A, Reyes CL, Altshuler A, Huang F, Hession C, Flavier A, Favis M, Tran H, Ailor E, Levesque M, Murphy T, Berquist L, Tamraz S, Snipas T, Garber E, Shestowsky WS, Rennard R, Graff CP, Wu X, Snyder W, Cole L, Gregson D, Shields M, Ho SN, Reff ME, Glaser SM, Dong J, Demarest SJ, Hariharan K.

J Biol Chem. 2009 Apr 10;284(15):10254-67. doi: 10.1074/jbc.M809709200. Epub 2009 Feb 11.


The identification of ganglion cells in Hirschsprung disease by the immunohistochemical detection of ret oncoprotein.

Karim S, Hession C, Marconi S, Gang DL, Otis CN.

Am J Clin Pathol. 2006 Jul;126(1):49-54.


LINGO-1 negatively regulates myelination by oligodendrocytes.

Mi S, Miller RH, Lee X, Scott ML, Shulag-Morskaya S, Shao Z, Chang J, Thill G, Levesque M, Zhang M, Hession C, Sah D, Trapp B, He Z, Jung V, McCoy JM, Pepinsky RB.

Nat Neurosci. 2005 Jun;8(6):745-51. Epub 2005 May 15.


BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF.

Thompson JS, Bixler SA, Qian F, Vora K, Scott ML, Cachero TG, Hession C, Schneider P, Sizing ID, Mullen C, Strauch K, Zafari M, Benjamin CD, Tschopp J, Browning JL, Ambrose C.

Science. 2001 Sep 14;293(5537):2108-11. Epub 2001 Aug 16.


Developmental regulation of GDNF response and receptor expression in the enteric nervous system.

Worley DS, Pisano JM, Choi ED, Walus L, Hession CA, Cate RL, Sanicola M, Birren SJ.

Development. 2000 Oct;127(20):4383-93.


The murine anti-human common gamma chain monoclonal antibody CP.B8 blocks the second step in the formation of the intermediate affinity IL-2 receptor.

Baker DP, Whitty A, Zafari MR, Olson DL, Hession CA, Miatkowski K, Avedissian LS, Foley SF, McKay ML, Benjamin CD, Burkly LC.

Biochemistry. 1998 Oct 13;37(41):14337-49.


Molecular mapping with functional antibodies localizes critical sites on the human IL receptor common gamma (gamma c) chain.

Raskin N, Jakubowski A, Sizing ID, Olson DL, Kalled SL, Hession CA, Benjamin CD, Baker DP, Burkly LC.

J Immunol. 1998 Oct 1;161(7):3474-83.


Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury.

Ichimura T, Bonventre JV, Bailly V, Wei H, Hession CA, Cate RL, Sanicola M.

J Biol Chem. 1998 Feb 13;273(7):4135-42.


Genomic structure and chromosomal localization of the human GDNFR-alpha gene.

Eng C, Myers SM, Kogon MD, Sanicola M, Hession C, Cate RL, Mulligan LM.

Oncogene. 1998 Feb 5;16(5):597-601.


TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis.

Chicheportiche Y, Bourdon PR, Xu H, Hsu YM, Scott H, Hession C, Garcia I, Browning JL.

J Biol Chem. 1997 Dec 19;272(51):32401-10.


Cytotoxic activities of recombinant soluble murine lymphotoxin-alpha and lymphotoxin-alpha beta complexes.

Mackay F, Bourdon PR, Griffiths DA, Lawton P, Zafari M, Sizing ID, Miatkowski K, Ngam-ek A, Benjamin CD, Hession C, Ambrose CM, Meier W, Browning JL.

J Immunol. 1997 Oct 1;159(7):3299-310.


Characterization of lymphotoxin-alpha beta complexes on the surface of mouse lymphocytes.

Browning JL, Sizing ID, Lawton P, Bourdon PR, Rennert PD, Majeau GR, Ambrose CM, Hession C, Miatkowski K, Griffiths DA, Ngam-ek A, Meier W, Benjamin CD, Hochman PS.

J Immunol. 1997 Oct 1;159(7):3288-98.


Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins.

Sanicola M, Hession C, Worley D, Carmillo P, Ehrenfels C, Walus L, Robinson S, Jaworski G, Wei H, Tizard R, Whitty A, Pepinsky RB, Cate RL.

Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6238-43.


Preparation and characterization of soluble recombinant heterotrimeric complexes of human lymphotoxins alpha and beta.

Browning JL, Miatkowski K, Griffiths DA, Bourdon PR, Hession C, Ambrose CM, Meier W.

J Biol Chem. 1996 Apr 12;271(15):8618-26.


Mouse lymphotoxin-beta receptor. Molecular genetics, ligand binding, and expression.

Force WR, Walter BN, Hession C, Tizard R, Kozak CA, Browning JL, Ware CF.

J Immunol. 1995 Dec 1;155(11):5280-8.


Expression of relB is required for the development of thymic medulla and dendritic cells.

Burkly L, Hession C, Ogata L, Reilly C, Marconi LA, Olson D, Tizard R, Cate R, Lo D.

Nature. 1995 Feb 9;373(6514):531-6.


A lymphotoxin-beta-specific receptor.

Crowe PD, VanArsdale TL, Walter BN, Ware CF, Hession C, Ehrenfels B, Browning JL, Din WS, Goodwin RG, Smith CA.

Science. 1994 Apr 29;264(5159):707-10.


Isolation of bovine kidney leucine aminopeptidase cDNA: comparison with the lens enzyme and tissue-specific expression of two mRNAs.

Wallner BP, Hession C, Tizard R, Frey AZ, Zuliani A, Mura C, Jahngen-Hodge J, Taylor A.

Biochemistry. 1993 Sep 14;32(36):9296-301.


Cloning of an inflammation-specific phosphatidyl inositol-linked form of murine vascular cell adhesion molecule-1.

Moy P, Lobb R, Tizard R, Olson D, Hession C.

J Biol Chem. 1993 Apr 25;268(12):8835-41.


Lymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface.

Browning JL, Ngam-ek A, Lawton P, DeMarinis J, Tizard R, Chow EP, Hession C, O'Brine-Greco B, Foley SF, Ware CF.

Cell. 1993 Mar 26;72(6):847-56.


Structure/function studies on vascular cell adhesion molecule-1.

Pepinsky B, Hession C, Chen LL, Moy P, Burkly L, Jakubowski A, Chow EP, Benjamin C, Chi-Rosso G, Luhowskyj S, et al.

J Biol Chem. 1992 Sep 5;267(25):17820-6.


Expression, purification and biochemical comparison of natural and recombinant human non-pancreatic phospholipase A2.

Johansen B, Kramer RM, Hession C, McGray P, Pepinsky RB.

Biochem Biophys Res Commun. 1992 Aug 31;187(1):544-51.


Cloning of murine and rat vascular cell adhesion molecule-1.

Hession C, Moy P, Tizard R, Chisholm P, Williams C, Wysk M, Burkly L, Miyake K, Kincade P, Lobb R.

Biochem Biophys Res Commun. 1992 Feb 28;183(1):163-9.


Activation of endothelial-leukocyte adhesion molecule 1 (ELAM-1) gene transcription.

Montgomery KF, Osborn L, Hession C, Tizard R, Goff D, Vassallo C, Tarr PI, Bomsztyk K, Lobb R, Harlan JM, et al.

Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6523-7.


Cloning of an alternate form of vascular cell adhesion molecule-1 (VCAM1).

Hession C, Tizard R, Vassallo C, Schiffer SB, Goff D, Moy P, Chi-Rosso G, Luhowskyj S, Lobb R, Osborn L.

J Biol Chem. 1991 Apr 15;266(11):6682-5.


ELFT: a gene that directs the expression of an ELAM-1 ligand.

Goelz SE, Hession C, Goff D, Griffiths B, Tizard R, Newman B, Chi-Rosso G, Lobb R.

Cell. 1990 Dec 21;63(6):1349-56.


A blocking monoclonal antibody to endothelial-leukocyte adhesion molecule-1 (ELAM1).

Benjamin C, Dougas I, Chi-Rosso G, Luhowskyj S, Rosa M, Newman B, Osborn L, Vassallo C, Hession C, Goelz S, et al.

Biochem Biophys Res Commun. 1990 Aug 31;171(1):348-53.


Endothelial leukocyte adhesion molecule 1: direct expression cloning and functional interactions.

Hession C, Osborn L, Goff D, Chi-Rosso G, Vassallo C, Pasek M, Pittack C, Tizard R, Goelz S, McCarthy K, et al.

Proc Natl Acad Sci U S A. 1990 Mar;87(5):1673-7.


Structure and properties of a secretable phospholipase A2 from human platelets.

Kramer RM, Johansen B, Hession C, Pepinsky RB.

Adv Exp Med Biol. 1990;275:35-53. Review. No abstract available.


Characterization of a secretable phospholipase A2 from human platelets.

Kramer RM, Johansen B, Hession C, Pepinsky RB.

Adv Prostaglandin Thromboxane Leukot Res. 1990;20:79-86. Review. No abstract available.


Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes.

Osborn L, Hession C, Tizard R, Vassallo C, Luhowskyj S, Chi-Rosso G, Lobb R.

Cell. 1989 Dec 22;59(6):1203-11.


Structure and properties of a human non-pancreatic phospholipase A2.

Kramer RM, Hession C, Johansen B, Hayes G, McGray P, Chow EP, Tizard R, Pepinsky RB.

J Biol Chem. 1989 Apr 5;264(10):5768-75.


Plasminogen activator inhibitor 2: regulation of gene transcription during phorbol ester-mediated differentiation of U-937 human histiocytic lymphoma cells.

Schleuning WD, Medcalf RL, Hession C, Rothenbühler R, Shaw A, Kruithof EK.

Mol Cell Biol. 1987 Dec;7(12):4564-7.


Primary structure of lymphocyte function-associated antigen 3 (LFA-3). The ligand of the T lymphocyte CD2 glycoprotein.

Wallner BP, Frey AZ, Tizard R, Mattaliano RJ, Hession C, Sanders ME, Dustin ML, Springer TA.

J Exp Med. 1987 Oct 1;166(4):923-32.


Uromodulin (Tamm-Horsfall glycoprotein): a renal ligand for lymphokines.

Hession C, Decker JM, Sherblom AP, Kumar S, Yue CC, Mattaliano RJ, Tizard R, Kawashima E, Schmeissner U, Heletky S, et al.

Science. 1987 Sep 18;237(4821):1479-84.


Nucleotide sequence of a cDNA encoding murine CSF-1 (Macrophage-CSF).

DeLamarter JF, Hession C, Semon D, Gough NM, Rothenbuhler R, Mermod JJ.

Nucleic Acids Res. 1987 Mar 11;15(5):2389-90. No abstract available.


Two human 35 kd inhibitors of phospholipase A2 are related to substrates of pp60v-src and of the epidermal growth factor receptor/kinase.

Huang KS, Wallner BP, Mattaliano RJ, Tizard R, Burne C, Frey A, Hession C, McGray P, Sinclair LK, Chow EP, et al.

Cell. 1986 Jul 18;46(2):191-9.


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