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Latest Updates on Lipid Management.

Egom EE, Pharithi RB, Hesse S, Starr N, Armstrong R, Sulaiman HM, Gazdikova K, Mozos I, Caprnda M, Kubatka P, Kruzliak P, Khan B, Gaspar L, Maher VMG.

High Blood Press Cardiovasc Prev. 2019 Mar 15. doi: 10.1007/s40292-019-00306-8. [Epub ahead of print] Review.


Early after Administration [11C]PiB PET Images Correlate with Cognitive Dysfunction Measured by the CERAD Test Battery.

Tiepolt S, Luthardt J, Patt M, Hesse S, Hoffmann KT, Weise D, Gertz HJ, Sabri O, Barthel H.

J Alzheimers Dis. 2019;68(1):65-76. doi: 10.3233/JAD-180217.


Proteome analysis of human neutrophil granulocytes from patients with monogenic disease using data-independent acquisition.

Grabowski P, Hesse S, Hollizeck S, Rohlfs M, Behrends U, Sherkat R, Tamary H, Ünal E, Somech R, Patıroğlu T, Canzar S, van der Werff Ten Bosch J, Klein C, Rappsilber J.

Mol Cell Proteomics. 2019 Jan 10. pii: mcp.RA118.001141. doi: 10.1074/mcp.RA118.001141. [Epub ahead of print]


Dual Time-Point [18F]Florbetaben PET Delivers Dual Biomarker Information in Mild Cognitive Impairment and Alzheimer's Disease.

Florek L, Tiepolt S, Schroeter ML, Berrouschot J, Saur D, Hesse S, Jochimsen T, Luthardt J, Sattler B, Patt M, Hoffmann KT, Villringer A, Classen J, Gertz HJ, Sabri O, Barthel H.

J Alzheimers Dis. 2018;66(3):1105-1116. doi: 10.3233/JAD-180522.


Central noradrenaline transporter availability is linked with HPA axis responsiveness and copeptin in human obesity and non-obese controls.

Schinke C, Hesse S, Rullmann M, Becker GA, Luthardt J, Zientek F, Patt M, Stoppe M, Schmidt E, Meyer K, Meyer PM, Orthgieß J, Blüher M, Kratzsch J, Ding YS, Then Bergh F, Sabri O.

Stress. 2018 Oct 29:1-10. doi: 10.1080/10253890.2018.1511698. [Epub ahead of print]


"Real-Time" High-Throughput Drug and Synergy Testing for Multidrug-Resistant Bacterial Infection: A Case Report.

Sun W, Hesse S, Xu M, Childs RW, Zheng W, Williamson PR.

Front Med (Lausanne). 2018 Sep 20;5:267. doi: 10.3389/fmed.2018.00267. eCollection 2018.


Descriptive epidemiology of snakebites in the Veraguas province of Panama, 2007-2008.

Pecchio M, Suárez JA, Hesse S, Hersh AM, Gundacker ND.

Trans R Soc Trop Med Hyg. 2018 Oct 1;112(10):463-466. doi: 10.1093/trstmh/try076.


Cognitive correlates of α4β2 nicotinic acetylcholine receptors in mild Alzheimer's dementia.

Sabri O, Meyer PM, Gräf S, Hesse S, Wilke S, Becker GA, Rullmann M, Patt M, Luthardt J, Wagenknecht G, Hoepping A, Smits R, Franke A, Sattler B, Tiepolt S, Fischer S, Deuther-Conrad W, Hegerl U, Barthel H, Schönknecht P, Brust P.

Brain. 2018 Jun 1;141(6):1840-1854. doi: 10.1093/brain/awy099.


Noradrenaline transporter availability on [11C]MRB PET predicts weight loss success in highly obese adults.

Vettermann FJ, Rullmann M, Becker GA, Luthardt J, Zientek F, Patt M, Meyer PM, McLeod A, Brendel M, Blüher M, Stumvoll M, Hilbert A, Ding YS, Sabri O, Hesse S.

Eur J Nucl Med Mol Imaging. 2018 Jul;45(9):1618-1625. doi: 10.1007/s00259-018-4002-7. Epub 2018 Apr 7.


Diabetes and Blood Glucose Disorders Under Anti-PD1.

Magis Q, Gaudy-Marqueste C, Basire A, Loundou A, Malissen N, Troin L, Monestier S, Mallet S, Hesse S, Richard MA, Valéro R, Beliard S, Grob JJ.

J Immunother. 2018 Jun;41(5):232-240. doi: 10.1097/CJI.0000000000000218.


Reduced H3K27me3 Expression is Common in Nodular Melanomas of Childhood Associated With Congenital Melanocytic Nevi But Not in Proliferative Nodules.

Macagno N, Etchevers HC, Malissen N, Rome A, Hesse S, Mallet S, Degardin N, Gaudy C.

Am J Surg Pathol. 2018 May;42(5):701-704. doi: 10.1097/PAS.0000000000001026. No abstract available.


Solvent Transfer-Efficiency of Risk Management Measures.

Bluemlein K, Elend M, Meijster T, Margary A, Tibaldi R, Hahn S, Hesse S.

Ann Work Expo Health. 2017 Dec 15;62(1):112-123. doi: 10.1093/annweh/wxx090. Review.


Between-User Reliability of Tier 1 Exposure Assessment Tools Used Under REACH.

Lamb J, Galea KS, Miller BG, Hesse S, Van Tongeren M.

Ann Work Expo Health. 2017 Oct 1;61(8):939-953. doi: 10.1093/annweh/wxx074.


Evaluation of Tier One Exposure Assessment Models (ETEAM): Project Overview and Methods.

Tischer M, Lamb J, Hesse S, van Tongeren M.

Ann Work Expo Health. 2017 Oct 1;61(8):911-920. doi: 10.1093/annweh/wxx066. No abstract available.


Validation of Lower Tier Exposure Tools Used for REACH: Comparison of Tools Estimates With Available Exposure Measurements.

van Tongeren M, Lamb J, Cherrie JW, MacCalman L, Basinas I, Hesse S.

Ann Work Expo Health. 2017 Oct 1;61(8):921-938. doi: 10.1093/annweh/wxx056.


[PROtocol-based MObilizaTION on intensive care units : Design of a cluster randomized pilot study].

Nydahl P, Diers A, Günther U, Haastert B, Hesse S, Kerschensteiner C, Klarmann S, Köpke S.

Med Klin Intensivmed Notfmed. 2018 Oct;113(7):581-592. doi: 10.1007/s00063-017-0358-x. Review. German.


Controlling charge-transfer properties through a microwave-assisted mono- or bis-annulation of dialkynyl-N-(het)arylpyrroles.

Pierrat P, Hesse S, Cebrián C, Gros PC.

Org Biomol Chem. 2017 Oct 18;15(40):8568-8575. doi: 10.1039/c7ob02149f.


News and views on in-vivo imaging of neurotransmission using PET and MRI.

Sander CY, Hesse S.

Q J Nucl Med Mol Imaging. 2017 Dec;61(4):414-428. doi: 10.23736/S1824-4785.17.03019-9. Epub 2017 Jul 27. Review.


The association between in vivo central noradrenaline transporter availability and trait impulsivity.

Hesse S, Müller U, Rullmann M, Luthardt J, Bresch A, Becker GA, Zientek F, Patt M, Meyer PM, Blüher M, Strauß M, Fenske W, Hankir M, Ding YS, Hilbert A, Sabri O.

Psychiatry Res Neuroimaging. 2017 Sep 30;267:9-14. doi: 10.1016/j.pscychresns.2017.06.013. Epub 2017 Jun 23.


Serotonin transporter gene promoter methylation status correlates with in vivo prefrontal 5-HTT availability and reward function in human obesity.

Drabe M, Rullmann M, Luthardt J, Boettcher Y, Regenthal R, Ploetz T, Becker GA, Patt M, Schinke C, Bergh FT, Zientek F, Hilbert A, Bresch A, Fenske W, Hankir MK, Sabri O, Hesse S.

Transl Psychiatry. 2017 Jul 4;7(7):e1167. doi: 10.1038/tp.2017.133.


Hunger and disinhibition but not cognitive restraint are associated with central norepinephrine transporter availability.

Bresch A, Rullmann M, Luthardt J, Becker GA, Patt M, Ding YS, Hilbert A, Sabri O, Hesse S.

Appetite. 2017 Oct 1;117:270-274. doi: 10.1016/j.appet.2017.06.020. Epub 2017 Jun 21.


Penicillium citrinum: Opportunistic pathogen or idle bystander? A case analysis with demonstration of galactomannan cross-reactivity.

Hesse SE, Luethy PM, Beigel JH, Zelazny AM.

Med Mycol Case Rep. 2017 May 22;17:8-10. doi: 10.1016/j.mmcr.2017.05.003. eCollection 2017 Sep.


Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.

Mattei D, Ivanov A, Ferrai C, Jordan P, Guneykaya D, Buonfiglioli A, Schaafsma W, Przanowski P, Deuther-Conrad W, Brust P, Hesse S, Patt M, Sabri O, Ross TL, Eggen BJL, Boddeke EWGM, Kaminska B, Beule D, Pombo A, Kettenmann H, Wolf SA.

Transl Psychiatry. 2017 May 9;7(5):e1120. doi: 10.1038/tp.2017.80.


[Evaluation of practices in the management of scabies in children].

Lê MS, Richard MA, Baumstarck K, Hesse S, Gaudy-Marqueste C, Grob JJ, Mallet S; le groupe de recherche en dermatologie pédiatrique de la Société Française de Dermatologie.

Ann Dermatol Venereol. 2017 May;144(5):341-348. doi: 10.1016/j.annder.2016.12.008. Epub 2017 Apr 10. French.


Poikiloderma with Neutropenia in Morocco: a Report of Four Cases.

Aglaguel A, Abdelghaffar H, Ailal F, Habti N, Hesse S, Kohistani N, Klein C, Bousfiha AA.

J Clin Immunol. 2017 May;37(4):357-362. doi: 10.1007/s10875-017-0385-7. Epub 2017 Mar 28.


Arterial Thromboses Heralding Cholangiocarcinoma.

Dunn T, Rudrapatna VA, Hesse S, Sargsyan Z.

Am J Med. 2017 Aug;130(8):e341-e342. doi: 10.1016/j.amjmed.2017.02.020. Epub 2017 Mar 24. No abstract available.


Feasibility of in vivo 18F-florbetaben PET/MR imaging of human carotid amyloid-β.

Bucerius J, Barthel H, Tiepolt S, Werner P, Sluimer JC, Wildberger JE, Patt M, Hesse S, Gertz HJ, Biessen EAL, Mottaghy FM, Sabri O.

Eur J Nucl Med Mol Imaging. 2017 Jul;44(7):1119-1128. doi: 10.1007/s00259-017-3651-2. Epub 2017 Mar 21.


Infrared pupillometry helps to detect and predict delirium in the post-anesthesia care unit.

Yang E, Kreuzer M, Hesse S, Davari P, Lee SC, García PS.

J Clin Monit Comput. 2018 Apr;32(2):359-368. doi: 10.1007/s10877-017-0009-z. Epub 2017 Mar 8.


Anesthetic Management of a Patient With Multiple Previous Episodes of Postanesthesia Care Unit Delirium: A Case Report.

Kreuzer M, Whalin MK, Hesse SDW, Riso MA, García PS.

A A Case Rep. 2017 Jun 15;8(12):311-315. doi: 10.1213/XAA.0000000000000497.


Test-retest measurements of dopamine D1-type receptors using simultaneous PET/MRI imaging.

Kaller S, Rullmann M, Patt M, Becker GA, Luthardt J, Girbardt J, Meyer PM, Werner P, Barthel H, Bresch A, Fritz TH, Hesse S, Sabri O.

Eur J Nucl Med Mol Imaging. 2017 Jun;44(6):1025-1032. doi: 10.1007/s00259-017-3645-0. Epub 2017 Feb 14.


Post-dexamethasone serum copeptin corresponds to HPA axis responsiveness in human obesity.

Schinke C, Hesse S, Stoppe M, Meyer K, Schmidt E, Orthgiess J, Bechmann L, Bresch A, Rullmann M, Luthardt J, Sabri O, Blüher M, Kratzsch J, Then Bergh F.

Psychoneuroendocrinology. 2017 Apr;78:39-47. doi: 10.1016/j.psyneuen.2017.01.004. Epub 2017 Jan 16.


Suppressed Fat Appetite after Roux-en-Y Gastric Bypass Surgery Associates with Reduced Brain μ-opioid Receptor Availability in Diet-Induced Obese Male Rats.

Hankir MK, Patt M, Patt JT, Becker GA, Rullmann M, Kranz M, Deuther-Conrad W, Schischke K, Seyfried F, Brust P, Hesse S, Sabri O, Krügel U, Fenske WK.

Front Neurosci. 2017 Jan 13;10:620. doi: 10.3389/fnins.2016.00620. eCollection 2016.


[123I]FP-CIT ENC-DAT normal database: the impact of the reconstruction and quantification methods.

Tossici-Bolt L, Dickson JC, Sera T, Booij J, Asenbaun-Nan S, Bagnara MC, Borght TV, Jonsson C, de Nijs R, Hesse S, Koulibaly PM, Akdemir UO, Koole M, Tatsch K, Varrone A.

EJNMMI Phys. 2017 Dec;4(1):8. doi: 10.1186/s40658-017-0175-6. Epub 2017 Jan 28.


The impact of reconstruction and scanner characterisation on the diagnostic capability of a normal database for [123I]FP-CIT SPECT imaging.

Dickson JC, Tossici-Bolt L, Sera T, Booij J, Ziebell M, Morbelli S, Assenbaum-Nan S, Borght TV, Pagani M, Kapucu OL, Hesse S, Van Laere K, Darcourt J, Varrone A, Tatsch K.

EJNMMI Res. 2017 Dec;7(1):10. doi: 10.1186/s13550-016-0253-0. Epub 2017 Jan 24.


Dissociation Between Brown Adipose Tissue 18F-FDG Uptake and Thermogenesis in Uncoupling Protein 1-Deficient Mice.

Hankir MK, Kranz M, Keipert S, Weiner J, Andreasen SG, Kern M, Patt M, Klöting N, Heiker JT, Brust P, Hesse S, Jastroch M, Fenske WK.

J Nucl Med. 2017 Jul;58(7):1100-1103. doi: 10.2967/jnumed.116.186460. Epub 2017 Jan 12.


Central noradrenaline transporter availability in highly obese, non-depressed individuals.

Hesse S, Becker GA, Rullmann M, Bresch A, Luthardt J, Hankir MK, Zientek F, Reißig G, Patt M, Arelin K, Lobsien D, Müller U, Baldofski S, Meyer PM, Blüher M, Fasshauer M, Fenske WK, Stumvoll M, Hilbert A, Ding YS, Sabri O.

Eur J Nucl Med Mol Imaging. 2017 Jun;44(6):1056-1064. doi: 10.1007/s00259-016-3590-3. Epub 2017 Jan 9.


Gastric Bypass Surgery Recruits a Gut PPAR-α-Striatal D1R Pathway to Reduce Fat Appetite in Obese Rats.

Hankir MK, Seyfried F, Hintschich CA, Diep TA, Kleberg K, Kranz M, Deuther-Conrad W, Tellez LA, Rullmann M, Patt M, Teichert J, Hesse S, Sabri O, Brust P, Hansen HS, de Araujo IE, Krügel U, Fenske WK.

Cell Metab. 2017 Feb 7;25(2):335-344. doi: 10.1016/j.cmet.2016.12.006. Epub 2017 Jan 5.


Erratum to: The need of standardization and of large clinical studies in an emerging indication of [18 F]FDG PET: the autoimmune encephalitis.

Morbelli S, Arbizu J, Booij J, Chen MK, Chetelat G, Cross DJ, Djekidel M, Drzezga A, Ekmekcioglu O, Garibotto V, Hesse S, Ishii K, Jafari L, Lammertsma AA, Law I, Mathews D, Minoshima S, Mosci K, Pagani M, Pappata S, Silverman DH, Signore A, Van De Giessen E, Villemagne V, Barthel H; European Association of Nuclear Medicine (EANM) and of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).

Eur J Nucl Med Mol Imaging. 2017 Mar;44(3):559-560. doi: 10.1007/s00259-016-3598-8. No abstract available.


Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice.

Weiner J, Kranz M, Klöting N, Kunath A, Steinhoff K, Rijntjes E, Köhrle J, Zeisig V, Hankir M, Gebhardt C, Deuther-Conrad W, Heiker JT, Kralisch S, Stumvoll M, Blüher M, Sabri O, Hesse S, Brust P, Tönjes A, Krause K.

Sci Rep. 2016 Dec 12;6:38124. doi: 10.1038/srep38124.


The need of standardization and of large clinical studies in an emerging indication of [18F]FDG PET: the autoimmune encephalitis.

Morbelli S, Arbizu J, Booij J, Chen MK, Chetelat G, Cross DJ, Djekidel M, Drzezga A, Ekmekcioglu O, Garibotto V, Hesse S, Ishii K, Jafari L, Lammertsma AA, Law I, Mathews D, Minoshima S, Mosci K, Pagani M, Pappata S, Silverman DH, Signore A, Van De Giessen E, Villemagne V, Barthel H; European Association of Nuclear Medicine (EANM) and of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).

Eur J Nucl Med Mol Imaging. 2017 Mar;44(3):353-357. doi: 10.1007/s00259-016-3589-9. Epub 2016 Dec 6. No abstract available. Erratum in: Eur J Nucl Med Mol Imaging. 2017 Mar;44(3):559-560. Saraf LJ [corrected to Jafari L].


[Skin tumors in children].

Dégardin N, Jaloux C, Mallet S, Hesse S, Bardot J.

Ann Chir Plast Esthet. 2016 Oct;61(5):498-512. doi: 10.1016/j.anplas.2016.05.013. Epub 2016 Jun 30. French.


Emotional eating and in vivo norepinephrine transporter availability in obesity: A [11 C]MRB PET pilot study.

Bresch A, Rullmann M, Luthardt J, Becker GA, Reissig G, Patt M, Ding YS, Hilbert A, Sabri O, Hesse S.

Int J Eat Disord. 2017 Feb;50(2):152-156. doi: 10.1002/eat.22621. Epub 2016 Sep 9.


Evaluation of the Enantiomer Specific Biokinetics and Radiation Doses of [(18)F]Fluspidine-A New Tracer in Clinical Translation for Imaging of σ₁ Receptors.

Kranz M, Sattler B, Wüst N, Deuther-Conrad W, Patt M, Meyer PM, Fischer S, Donat CK, Wünsch B, Hesse S, Steinbach J, Brust P, Sabri O.

Molecules. 2016 Sep 1;21(9). pii: E1164. doi: 10.3390/molecules21091164.


Role of (18)F-FDG-PET imaging in the diagnosis of autoimmune encephalitis.

Morbelli S, Djekidel M, Hesse S, Pagani M, Barthel H; Neuroimaging Committee of the European Association of Nuclear Medicine (EANM); Brain Imaging Council of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).

Lancet Neurol. 2016 Sep;15(10):1009-10. doi: 10.1016/S1474-4422(16)30140-5. Epub 2016 Aug 8. No abstract available.


Effortful control as a dimension of temperament is negatively associated with prefrontal serotonin transporter availability in obese and non-obese individuals.

Zientek F, Winter K, Müller A, Rullmann M, Luthardt J, Becker GA, Bresch A, Patt M, Sabri O, Hilbert A, Hesse S.

Eur J Neurosci. 2016 Oct;44(7):2460-2466. doi: 10.1111/ejn.13362. Epub 2016 Aug 29.


Correction for Hesse et al., Serological Responses to a Norovirus Nonstructural Fusion Protein after Vaccination and Infection.

Hesse S, Neill FH, Estes MK, Shanker S, Prasad BV, Ferreira J, Atmar RL.

Clin Vaccine Immunol. 2016 Aug 5;23(8):735. doi: 10.1128/CVI.00260-16. Print 2016 Aug. No abstract available.


Feasibility and acceptance of simultaneous amyloid PET/MRI.

Schütz L, Lobsien D, Fritzsch D, Tiepolt S, Werner P, Schroeter ML, Berrouschot J, Saur D, Hesse S, Jochimsen T, Rullmann M, Sattler B, Patt M, Gertz HJ, Villringer A, Claßen J, Hoffmann KT, Sabri O, Barthel H.

Eur J Nucl Med Mol Imaging. 2016 Nov;43(12):2236-2243. Epub 2016 Jul 19.


Thoracic [18F]fluorodeoxyglucose uptake measured by positron emission tomography/computed tomography in pulmonary hypertension.

Frille A, Steinhoff KG, Hesse S, Grachtrup S, Wald A, Wirtz H, Sabri O, Seyfarth HJ.

Medicine (Baltimore). 2016 Jun;95(25):e3976. doi: 10.1097/MD.0000000000003976.


A novel thermoregulatory role for PDE10A in mouse and human adipocytes.

Hankir MK, Kranz M, Gnad T, Weiner J, Wagner S, Deuther-Conrad W, Bronisch F, Steinhoff K, Luthardt J, Klöting N, Hesse S, Seibyl JP, Sabri O, Heiker JT, Blüher M, Pfeifer A, Brust P, Fenske WK.

EMBO Mol Med. 2016 Jul 1;8(7):796-812. doi: 10.15252/emmm.201506085. Print 2016 Jul.


2-(Thienothiazolylimino)-1,3-thiazolidin-4-ones inhibit cell division cycle 25 A phosphatase.

Huber-Villaume S, Revelant G, Sibille E, Philippot S, Morabito A, Dunand S, Chaimbault P, Bagrel D, Kirsch G, Hesse S, Schohn H.

Bioorg Med Chem. 2016 Jul 1;24(13):2920-2928. doi: 10.1016/j.bmc.2016.04.063. Epub 2016 May 2.


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