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Items: 1 to 50 of 133

1.

A cellular census of human lungs identifies novel cell states in health and in asthma.

Vieira Braga FA, Kar G, Berg M, Carpaij OA, Polanski K, Simon LM, Brouwer S, Gomes T, Hesse L, Jiang J, Fasouli ES, Efremova M, Vento-Tormo R, Talavera-López C, Jonker MR, Affleck K, Palit S, Strzelecka PM, Firth HV, Mahbubani KT, Cvejic A, Meyer KB, Saeb-Parsy K, Luinge M, Brandsma CA, Timens W, Angelidis I, Strunz M, Koppelman GH, van Oosterhout AJ, Schiller HB, Theis FJ, van den Berge M, Nawijn MC, Teichmann SA.

Nat Med. 2019 Jul;25(7):1153-1163. doi: 10.1038/s41591-019-0468-5. Epub 2019 Jun 17.

PMID:
31209336
2.

Structural and functional imaging of large and opaque plant specimens.

Hesse L, Bunk K, Leupold J, Speck T, Masselter T.

J Exp Bot. 2019 Apr 24. pii: erz186. doi: 10.1093/jxb/erz186. [Epub ahead of print]

PMID:
31188449
3.

Subcutaneous immunotherapy using modified Phl p5a-derived peptides efficiently alleviates allergic asthma in mice.

Hesse L, Feenstra R, Ambrosini M, de Jager WA, Petersen A, Vietor H, Unger WWJ, van Kooyk Y, Nawijn MC.

Allergy. 2019 May 23. doi: 10.1111/all.13918. [Epub ahead of print] No abstract available.

PMID:
31124150
4.

Resolving form-structure-function relationships in plants with MRI for biomimetic transfer.

Hesse L, Leupold J, Poppinga S, Wick M, Strobel K, Masselter T, Speck T.

Integr Comp Biol. 2019 May 23. pii: icz051. doi: 10.1093/icb/icz051. [Epub ahead of print]

PMID:
31120532
5.

An Acinetobacter baumannii, Zinc-Regulated Peptidase Maintains Cell Wall Integrity during Immune-Mediated Nutrient Sequestration.

Lonergan ZR, Nairn BL, Wang J, Hsu YP, Hesse LE, Beavers WN, Chazin WJ, Trinidad JC, VanNieuwenhze MS, Giedroc DP, Skaar EP.

Cell Rep. 2019 Feb 19;26(8):2009-2018.e6. doi: 10.1016/j.celrep.2019.01.089.

6.

Increased Hematopoietic Extracellular RNAs and Vesicles in the Lung during Allergic Airway Responses.

Pua HH, Happ HC, Gray CJ, Mar DJ, Chiou NT, Hesse LE, Ansel KM.

Cell Rep. 2019 Jan 22;26(4):933-944.e4. doi: 10.1016/j.celrep.2019.01.002.

7.

The antioxidant transcription factor Nrf2 modulates the stress response and phenotype of malignant as well as premalignant pancreatic ductal epithelial cells by inducing expression of the ATF3 splicing variant ΔZip2.

Kha ML, Hesse L, Deisinger F, Sipos B, Röcken C, Arlt A, Sebens S, Helm O, Schäfer H.

Oncogene. 2019 Feb;38(9):1461-1476. doi: 10.1038/s41388-018-0518-3. Epub 2018 Oct 9.

PMID:
30302023
8.

Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology.

Post S, Heijink IH, Hesse L, Koo HK, Shaheen F, Fouadi M, Kuchibhotla VNS, Lambrecht BN, Van Oosterhout AJM, Hackett TL, Nawijn MC.

Sci Rep. 2018 Sep 5;8(1):13275. doi: 10.1038/s41598-018-31500-8.

9.

Finite element modelling of complex movements during self-sealing of ring incisions in leaves of Delosperma cooperi.

Klein H, Hesse L, Boljen M, Kampowski T, Butschek I, Speck T, Speck O.

J Theor Biol. 2018 Dec 7;458:184-206. doi: 10.1016/j.jtbi.2018.08.023. Epub 2018 Aug 24.

PMID:
30149008
10.

A qualitative analysis of the bud ontogeny of Dracaena marginata using high-resolution magnetic resonance imaging.

Hesse L, Leupold J, Speck T, Masselter T.

Sci Rep. 2018 Jun 29;8(1):9881. doi: 10.1038/s41598-018-27823-1.

11.

Increased spontaneous firing rates in auditory midbrain following noise exposure are specifically abolished by a Kv3 channel modulator.

Anderson LA, Hesse LL, Pilati N, Bakay WMH, Alvaro G, Large CH, McAlpine D, Schaette R, Linden JF.

Hear Res. 2018 Aug;365:77-89. doi: 10.1016/j.heares.2018.04.012. Epub 2018 Apr 30.

PMID:
29773471
12.

Subcutaneous immunotherapy suppresses Th2 inflammation and induces neutralizing antibodies, but sublingual immunotherapy suppresses airway hyperresponsiveness in grass pollen mouse models for allergic asthma.

Hesse L, Brouwer U, Petersen AH, Gras R, Bosman L, Brimnes J, Oude Elberink JNG, van Oosterhout AJM, Nawijn MC.

Clin Exp Allergy. 2018 Aug;48(8):1035-1049. doi: 10.1111/cea.13169. Epub 2018 Jun 8.

PMID:
29752757
13.

Subcutaneous immunotherapy with purified Der p1 and 2 suppresses type 2 immunity in a murine asthma model.

Hesse L, van Ieperen N, Habraken C, Petersen AH, Korn S, Smilda T, Goedewaagen B, Ruiters MH, van der Graaf AC, Nawijn MC.

Allergy. 2018 Apr;73(4):862-874. doi: 10.1111/all.13382. Epub 2018 Jan 31.

14.

Subcutaneous and Sublingual Immunotherapy in a Mouse Model of Allergic Asthma.

Hesse L, Nawijn MC.

Methods Mol Biol. 2017;1559:137-168. doi: 10.1007/978-1-4939-6786-5_11.

PMID:
28063043
15.

Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD.

Pouwels SD, Hesse L, Faiz A, Lubbers J, Bodha PK, Ten Hacken NH, van Oosterhout AJ, Nawijn MC, Heijink IH.

Am J Physiol Lung Cell Mol Physiol. 2016 Nov 1;311(5):L881-L892. doi: 10.1152/ajplung.00135.2016. Epub 2016 Sep 9.

16.

Non-Monotonic Relation between Noise Exposure Severity and Neuronal Hyperactivity in the Auditory Midbrain.

Hesse LL, Bakay W, Ong HC, Anderson L, Ashmore J, McAlpine D, Linden J, Schaette R.

Front Neurol. 2016 Aug 25;7:133. doi: 10.3389/fneur.2016.00133. eCollection 2016.

17.

Magnetic resonance imaging reveals functional anatomy and biomechanics of a living dragon tree.

Hesse L, Masselter T, Leupold J, Spengler N, Speck T, Korvink JG.

Sci Rep. 2016 Sep 8;6:32685. doi: 10.1038/srep32685.

18.

Biomimetic optimisation of branched fibre-reinforced composites in engineering by detailed analyses of biological concept generators.

Masselter T, Hesse L, Böhm H, Gruhl A, Schwager H, Leupold J, Gude M, Milwich M, Neinhuis C, Speck T.

Bioinspir Biomim. 2016 Sep 7;11(5):055005. doi: 10.1088/1748-3190/11/5/055005.

PMID:
27603330
19.

Biomechanics and functional morphology of a climbing monocot.

Hesse L, Wagner ST, Neinhuis C.

AoB Plants. 2016 Jan 27;8. pii: plw005. doi: 10.1093/aobpla/plw005.

20.

Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice.

Pouwels SD, Zijlstra GJ, van der Toorn M, Hesse L, Gras R, Ten Hacken NH, Krysko DV, Vandenabeele P, de Vries M, van Oosterhout AJ, Heijink IH, Nawijn MC.

Am J Physiol Lung Cell Mol Physiol. 2016 Feb 15;310(4):L377-86. doi: 10.1152/ajplung.00174.2015. Epub 2015 Dec 30.

21.

Pim1 kinase activity preserves airway epithelial integrity upon house dust mite exposure.

de Vries M, Hesse L, Jonker MR, van den Berge M, van Oosterhout AJ, Heijink IH, Nawijn MC.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 1;309(11):L1344-53. doi: 10.1152/ajplung.00043.2015. Epub 2015 Oct 9.

22.

Major trends in stem anatomy and growth forms in the perianth-bearing Piperales, with special focus on Aristolochia.

Wagner ST, Hesse L, Isnard S, Samain MS, Bolin J, Maass E, Neinhuis C, Rowe NP, Wanke S.

Ann Bot. 2014 Jun;113(7):1139-54. doi: 10.1093/aob/mcu044. Epub 2014 Apr 2.

23.

[Treatment of retinal arterial branch occlusion with transluminal Nd:YAG laser embolectomy].

Much MM, Hesse L.

Ophthalmologe. 2014 Feb;111(2):144-50. doi: 10.1007/s00347-013-2803-4. German.

PMID:
23681177
24.

[Intravitreal injection. Drugs to treat subretinal hemorrhage].

Hesse L.

Ophthalmologe. 2012 Jul;109(7):644-7. doi: 10.1007/s00347-012-2565-4. German.

PMID:
22752625
25.

Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues.

Court MH, Zhang X, Ding X, Yee KK, Hesse LM, Finel M.

Xenobiotica. 2012 Mar;42(3):266-77. doi: 10.3109/00498254.2011.618954. Epub 2011 Oct 13.

PMID:
21995321
26.

Web-based training in German university eye hospitals - Education 2.0?

Handzel DM, Hesse L.

GMS Z Med Ausbild. 2011;28(3):Doc43. doi: 10.3205/zma000755. Epub 2011 Aug 8.

27.

Genome data mining and soil survey for the novel group 5 [NiFe]-hydrogenase to explore the diversity and ecological importance of presumptive high-affinity H(2)-oxidizing bacteria.

Constant P, Chowdhury SP, Hesse L, Pratscher J, Conrad R.

Appl Environ Microbiol. 2011 Sep;77(17):6027-35. doi: 10.1128/AEM.00673-11. Epub 2011 Jul 8.

28.

Evidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion.

He X, Hesse LM, Hazarika S, Masse G, Harmatz JS, Greenblatt DJ, Court MH.

Br J Clin Pharmacol. 2009 Nov;68(5):721-30. doi: 10.1111/j.1365-2125.2009.03519.x.

29.
30.

In vitro activity of LK-157, a novel tricyclic carbapenem as broad-spectrum {beta}-lactamase inhibitor.

Paukner S, Hesse L, Prezelj A, Solmajer T, Urleb U.

Antimicrob Agents Chemother. 2009 Feb;53(2):505-11. doi: 10.1128/AAC.00085-08. Epub 2008 Dec 15.

31.

4-Substituted trinems as broad spectrum beta-lactamase inhibitors: structure-based design, synthesis, and biological activity.

Plantan I, Selic L, Mesar T, Anderluh PS, Oblak M, Prezelj A, Hesse L, Andrejasic M, Vilar M, Turk D, Kocijan A, Prevec T, Vilfan G, Kocjan D, Copar A, Urleb U, Solmajer T.

J Med Chem. 2007 Aug 23;50(17):4113-21. Epub 2007 Aug 1.

PMID:
17665896
32.

Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10.

Kaivosaari S, Toivonen P, Hesse LM, Koskinen M, Court MH, Finel M.

Mol Pharmacol. 2007 Sep;72(3):761-8. Epub 2007 Jun 18.

PMID:
17576790
33.

An optically powered single-channel stimulation implant as test system for chronic biocompatibility and biostability of miniaturized retinal vision prostheses.

Schanze T, Hesse L, Lau C, Greve N, Haberer W, Kammer S, Doerge T, Rentzos A, Stieglitz T.

IEEE Trans Biomed Eng. 2007 Jun;54(6 Pt 1):983-92.

PMID:
17554818
34.

Intraocular fluid-air exchange reduces retinal ganglion cell activity.

Schanze T, Hesse L.

Ophthalmologica. 2007;221(1):1-5.

PMID:
17183193
35.

Ritonavir has minimal impact on the pharmacokinetic disposition of a single dose of bupropion administered to human volunteers.

Hesse LM, Greenblatt DJ, von Moltke LL, Court MH.

J Clin Pharmacol. 2006 May;46(5):567-76.

PMID:
16638740
36.

Visual resolution with retinal implants estimated from recordings in cat visual cortex.

Eckhorn R, Wilms M, Schanze T, Eger M, Hesse L, Eysel UT, Kisvárday ZF, Zrenner E, Gekeler F, Schwahn H, Shinoda K, Sachs H, Walter P.

Vision Res. 2006 Sep;46(17):2675-90. Epub 2006 Mar 29.

37.

UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: I. Identification of polymorphisms in the 5'-regulatory and exon 1 regions, and association with human liver UGT1A6 gene expression and glucuronidation.

Krishnaswamy S, Hao Q, Al-Rohaimi A, Hesse LM, von Moltke LL, Greenblatt DJ, Court MH.

J Pharmacol Exp Ther. 2005 Jun;313(3):1331-9. Epub 2005 Mar 10.

PMID:
15761114
38.

UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: II. Functional impact of the three most common nonsynonymous UGT1A6 polymorphisms (S7A, T181A, and R184S).

Krishnaswamy S, Hao Q, Al-Rohaimi A, Hesse LM, von Moltke LL, Greenblatt DJ, Court MH.

J Pharmacol Exp Ther. 2005 Jun;313(3):1340-6. Epub 2005 Mar 10.

PMID:
15761113
39.

Retino-cortical information transmission achievable with a retina implant.

Eger M, Wilms M, Eckhorn R, Schanze T, Hesse L.

Biosystems. 2005 Jan-Mar;79(1-3):133-42.

PMID:
15649598
40.

Double-blind, placebo-controlled trial of octreotide long-acting repeatable (LAR) in thyroid-associated ophthalmopathy.

Dickinson AJ, Vaidya B, Miller M, Coulthard A, Perros P, Baister E, Andrews CD, Hesse L, Heverhagen JT, Heufelder AE, Kendall-Taylor P.

J Clin Endocrinol Metab. 2004 Dec;89(12):5910-5.

PMID:
15579735
41.

Subretinal implantation and testing of polyimide film electrodes in cats.

Sachs HG, Schanze T, Wilms M, Rentzos A, Brunner U, Gekeler F, Hesse L.

Graefes Arch Clin Exp Ophthalmol. 2005 May;243(5):464-8. Epub 2004 Dec 1.

PMID:
15578200
42.

Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes.

Hesse LM, He P, Krishnaswamy S, Hao Q, Hogan K, von Moltke LL, Greenblatt DJ, Court MH.

Pharmacogenetics. 2004 Apr;14(4):225-38. Erratum in: Pharmacogenetics. 2005 Apr;15(4):265.

PMID:
15083067
43.

Bilateral congenital dacryocystocele as a cause of respiratory distress in a newborn.

Teymoortash A, Hesse L, Werner JA, Lippert BM.

Rhinology. 2004 Mar;42(1):41-4.

PMID:
15072034
44.

Effect of age on in vitro triazolam biotransformation in male human liver microsomes.

Patki KC, von Moltke LL, Harmatz JS, Hesse LM, Court MH, Greenblatt DJ.

J Pharmacol Exp Ther. 2004 Mar;308(3):874-9. Epub 2003 Nov 21.

PMID:
14634046
45.

Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin.

Hesse LM, Sakai Y, Vishnuvardhan D, Li AP, von Moltke LL, Greenblatt DJ.

J Pharm Pharmacol. 2003 Sep;55(9):1229-39.

PMID:
14604466
46.

Functional and biochemical analysis of Chlamydia trachomatis MurC, an enzyme displaying UDP-N-acetylmuramate:amino acid ligase activity.

Hesse L, Bostock J, Dementin S, Blanot D, Mengin-Lecreulx D, Chopra I.

J Bacteriol. 2003 Nov;185(22):6507-12.

47.

[One-sided flicker with vision deterioration by high hypermetropia].

Schulze SD, Silva Papi MM, Hesse L.

Ophthalmologe. 2003 Jul;100(7):554-7. Epub 2003 Jun 26. German. No abstract available.

PMID:
12920557
48.

Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men.

Olubodun JO, Ochs HR, von Moltke LL, Roubenoff R, Hesse LM, Harmatz JS, Shader RI, Greenblatt DJ.

Br J Clin Pharmacol. 2003 Sep;56(3):297-304.

49.

Towards the cortical representation of form and motion stimuli generated by a retina implant.

Schanze T, Greve N, Hesse L.

Graefes Arch Clin Exp Ophthalmol. 2003 Aug;241(8):685-93. Epub 2003 Jul 29.

PMID:
12898282
50.

Clinically important drug interactions with zopiclone, zolpidem and zaleplon.

Hesse LM, von Moltke LL, Greenblatt DJ.

CNS Drugs. 2003;17(7):513-32. Review.

PMID:
12751920

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