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Items: 1 to 50 of 63

1.

Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3.

Lee CM, He CH, Park JW, Lee JH, Kamle S, Ma B, Akosman B, Cotez R, Chen E, Zhou Y, Herzog EL, Ryu C, Peng X, Rosas IO, Poli S, Bostwick CF, Choi AM, Elias JA, Lee CG.

Life Sci Alliance. 2019 May 13;2(3). pii: e201900350. doi: 10.26508/lsa.201900350. Print 2019 Jun.

2.

LMO7 Is a Negative Feedback Regulator of Transforming Growth Factor β Signaling and Fibrosis.

Xie Y, Ostriker AC, Jin Y, Hu H, Sizer AJ, Peng G, Morris AH, Ryu C, Herzog EL, Kyriakides T, Zhao H, Dardik A, Yu J, Hwa J, Martin KA.

Circulation. 2019 Jan 29;139(5):679-693. doi: 10.1161/CIRCULATIONAHA.118.034615.

PMID:
30586711
3.

A rare presentation of pulmonary sarcoidosis as a solitary lung mass: a case report.

Kelleher DW, Yaggi M, Homer R, Herzog EL, Ryu C.

J Med Case Rep. 2018 Apr 13;12(1):94. doi: 10.1186/s13256-018-1632-0.

4.

The Role of Immune and Inflammatory Cells in Idiopathic Pulmonary Fibrosis.

Desai O, Winkler J, Minasyan M, Herzog EL.

Front Med (Lausanne). 2018 Mar 20;5:43. doi: 10.3389/fmed.2018.00043. eCollection 2018. Review.

5.

S100A12 as a marker of worse cardiac output and mortality in pulmonary hypertension.

Tzouvelekis A, Herazo-Maya JD, Ryu C, Chu JH, Zhang Y, Gibson KF, Adonteng-Boateng PK, Li Q, Pan H, Cherry B, Ahmad F, Ford HJ, Herzog EL, Kaminski N, Fares WH.

Respirology. 2018 Aug;23(8):771-779. doi: 10.1111/resp.13302. Epub 2018 Apr 2.

6.

Semaphorin 7A in circulating regulatory T cells is increased in autosomal-dominant polycystic kidney disease and decreases with tolvaptan treatment.

Lee Y, Blount KL, Dai F, Thompson S, Scher JK, Bitterman S, Droher M, Herzog EL, Moeckel G, Karihaloo A, Dahl NK.

Clin Exp Nephrol. 2018 Aug;22(4):906-916. doi: 10.1007/s10157-018-1542-x. Epub 2018 Feb 16.

PMID:
29453607
7.

Pulmonary arterial hypertension in the setting of scleroderma is different than in the setting of lupus: A review.

Bazan IS, Mensah KA, Rudkovskaia AA, Adonteng-Boateng PK, Herzog EL, Buckley L, Fares WH.

Respir Med. 2018 Jan;134:42-46. doi: 10.1016/j.rmed.2017.11.020. Epub 2017 Dec 2. Review.

PMID:
29413506
8.

Human pericytes adopt myofibroblast properties in the microenvironment of the IPF lung.

Sava P, Ramanathan A, Dobronyi A, Peng X, Sun H, Ledesma-Mendoza A, Herzog EL, Gonzalez AL.

JCI Insight. 2017 Dec 21;2(24). pii: 96352. doi: 10.1172/jci.insight.96352.

9.

Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function.

Yu G, Tzouvelekis A, Wang R, Herazo-Maya JD, Ibarra GH, Srivastava A, de Castro JPW, DeIuliis G, Ahangari F, Woolard T, Aurelien N, Arrojo E Drigo R, Gan Y, Graham M, Liu X, Homer RJ, Scanlan TS, Mannam P, Lee PJ, Herzog EL, Bianco AC, Kaminski N.

Nat Med. 2018 Jan;24(1):39-49. doi: 10.1038/nm.4447. Epub 2017 Dec 4.

10.

Validation of a 52-gene risk profile for outcome prediction in patients with idiopathic pulmonary fibrosis: an international, multicentre, cohort study.

Herazo-Maya JD, Sun J, Molyneaux PL, Li Q, Villalba JA, Tzouvelekis A, Lynn H, Juan-Guardela BM, Risquez C, Osorio JC, Yan X, Michel G, Aurelien N, Lindell KO, Klesen MJ, Moffatt MF, Cookson WO, Zhang Y, Garcia JGN, Noth I, Prasse A, Bar-Joseph Z, Gibson KF, Zhao H, Herzog EL, Rosas IO, Maher TM, Kaminski N.

Lancet Respir Med. 2017 Nov;5(11):857-868. doi: 10.1016/S2213-2600(17)30349-1. Epub 2017 Sep 21.

11.

CCL2 and T cells in pulmonary fibrosis: an old player gets a new role.

Osafo-Addo AD, Herzog EL.

Thorax. 2017 Nov;72(11):967-968. doi: 10.1136/thoraxjnl-2017-210517. Epub 2017 Sep 7. No abstract available.

PMID:
28883089
12.

Myeloid-derived Suppressor Cells Are Necessary for Development of Pulmonary Hypertension.

Bryant AJ, Shenoy V, Fu C, Marek G, Lorentsen KJ, Herzog EL, Brantly ML, Avram D, Scott EW.

Am J Respir Cell Mol Biol. 2018 Feb;58(2):170-180. doi: 10.1165/rcmb.2017-0214OC.

13.

Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis.

Murray LA, Habiel DM, Hohmann M, Camelo A, Shang H, Zhou Y, Coelho AL, Peng X, Gulati M, Crestani B, Sleeman MA, Mustelin T, Moore MW, Ryu C, Osafo-Addo AD, Elias JA, Lee CG, Hu B, Herazo-Maya JD, Knight DA, Hogaboam CM, Herzog EL.

JCI Insight. 2017 Aug 17;2(16). pii: 92192. doi: 10.1172/jci.insight.92192. eCollection 2017 Aug 17.

14.

Extracellular Mitochondrial DNA Is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary Fibrosis.

Ryu C, Sun H, Gulati M, Herazo-Maya JD, Chen Y, Osafo-Addo A, Brandsdorfer C, Winkler J, Blaul C, Faunce J, Pan H, Woolard T, Tzouvelekis A, Antin-Ozerkis DE, Puchalski JT, Slade M, Gonzalez AL, Bogenhagen DF, Kirillov V, Feghali-Bostwick C, Gibson K, Lindell K, Herzog RI, Dela Cruz CS, Mehal W, Kaminski N, Herzog EL, Trujillo G.

Am J Respir Crit Care Med. 2017 Dec 15;196(12):1571-1581. doi: 10.1164/rccm.201612-2480OC.

15.

Upper Airway Obstruction Requiring Emergent Tracheostomy Secondary to Laryngeal Sarcoidosis: A Case Report.

Ryu C, Herzog EL, Pan H, Homer R, Gulati M.

Am J Case Rep. 2017 Feb 13;18:157-159.

16.

Validation of the prognostic value of MMP-7 in idiopathic pulmonary fibrosis.

Tzouvelekis A, Herazo-Maya JD, Slade M, Chu JH, Deiuliis G, Ryu C, Li Q, Sakamoto K, Ibarra G, Pan H, Gulati M, Antin-Ozerkis D, Herzog EL, Kaminski N.

Respirology. 2017 Apr;22(3):486-493. doi: 10.1111/resp.12920. Epub 2016 Oct 19.

17.

SH2 Domain-Containing Phosphatase-2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis.

Tzouvelekis A, Yu G, Lino Cardenas CL, Herazo-Maya JD, Wang R, Woolard T, Zhang Y, Sakamoto K, Lee H, Yi JS, DeIuliis G, Xylourgidis N, Ahangari F, Lee PJ, Aidinis V, Herzog EL, Homer R, Bennett AM, Kaminski N.

Am J Respir Crit Care Med. 2017 Feb 15;195(4):500-514. doi: 10.1164/rccm.201602-0329OC.

18.

Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis.

Peng X, Moore M, Mathur A, Zhou Y, Sun H, Gan Y, Herazo-Maya JD, Kaminski N, Hu X, Pan H, Ryu C, Osafo-Addo A, Homer RJ, Feghali-Bostwick C, Fares WH, Gulati M, Hu B, Lee CG, Elias JA, Herzog EL.

FASEB J. 2016 Dec;30(12):4056-4070. Epub 2016 Sep 8.

19.

Regulatory T Cells in Idiopathic Pulmonary Fibrosis: Too Much of a Good Thing?

Moore MW, Herzog EL.

Am J Pathol. 2016 Aug;186(8):1978-1981. doi: 10.1016/j.ajpath.2016.06.002. Epub 2016 Jun 23.

20.

RIG-like Helicase Regulation of Chitinase 3-like 1 Axis and Pulmonary Metastasis.

Ma B, Herzog EL, Moore M, Lee CM, Na SH, Lee CG, Elias JA.

Sci Rep. 2016 May 20;6:26299. doi: 10.1038/srep26299.

21.

The Airway in Idiopathic Pulmonary Fibrosis: Protecting the Lung or Promoting Disease?

Ryu C, Homer RJ, Herzog EL.

Am J Respir Crit Care Med. 2016 May 15;193(10):1081-2. doi: 10.1164/rccm.201601-0055ED. No abstract available.

22.

Right atrial pressure/pulmonary artery wedge pressure ratio: A more specific predictor of survival in pulmonary arterial hypertension.

Fares WH, Bellumkonda L, Tonelli AR, Carson SS, Hassoun PM, Trow TK, Herzog EL, Kaminski N, Kholdani CA, Zhang L, Zhou Y, Hammel JP, Dweik RA.

J Heart Lung Transplant. 2016 Jun;35(6):760-7. doi: 10.1016/j.healun.2015.12.028. Epub 2016 Jan 8.

PMID:
26856665
23.

Matrix-driven Myosin II Mediates the Pro-fibrotic Fibroblast Phenotype.

Southern BD, Grove LM, Rahaman SO, Abraham S, Scheraga RG, Niese KA, Sun H, Herzog EL, Liu F, Tschumperlin DJ, Egelhoff TT, Rosenfeld SS, Olman MA.

J Biol Chem. 2016 Mar 18;291(12):6083-95. doi: 10.1074/jbc.M115.712380. Epub 2016 Jan 13.

24.

Netrin-1 Regulates Fibrocyte Accumulation in the Decellularized Fibrotic Sclerodermatous Lung Microenvironment and in Bleomycin-Induced Pulmonary Fibrosis.

Sun H, Zhu Y, Pan H, Chen X, Balestrini JL, Lam TT, Kanyo JE, Eichmann A, Gulati M, Fares WH, Bai H, Feghali-Bostwick CA, Gan Y, Peng X, Moore MW, White ES, Sava P, Gonzalez AL, Cheng Y, Niklason LE, Herzog EL.

Arthritis Rheumatol. 2016 May;68(5):1251-61. doi: 10.1002/art.39575.

25.

Flow Cytometric Identification of Fibrocytes in the Human Circulation.

Hu X, DeBiasi EM, Herzog EL.

Methods Mol Biol. 2015;1343:19-33. doi: 10.1007/978-1-4939-2963-4_3.

PMID:
26420706
26.

Chitinase 3-like-1 and its receptors in Hermansky-Pudlak syndrome-associated lung disease.

Zhou Y, He CH, Herzog EL, Peng X, Lee CM, Nguyen TH, Gulati M, Gochuico BR, Gahl WA, Slade ML, Lee CG, Elias JA.

J Clin Invest. 2015 Aug 3;125(8):3178-92. doi: 10.1172/JCI79792. Epub 2015 Jun 29.

27.

Fate of distal lung epithelium cultured in a decellularized lung extracellular matrix.

Calle EA, Mendez JJ, Ghaedi M, Leiby KL, Bove PF, Herzog EL, Sundaram S, Niklason LE.

Tissue Eng Part A. 2015 Jun;21(11-12):1916-28. doi: 10.1089/ten.TEA.2014.0511. Epub 2015 May 4.

28.

Role of chitinase 3-like-1 and semaphorin 7a in pulmonary melanoma metastasis.

Ma B, Herzog EL, Lee CG, Peng X, Lee CM, Chen X, Rockwell S, Koo JS, Kluger H, Herbst RS, Sznol M, Elias JA.

Cancer Res. 2015 Feb 1;75(3):487-96. doi: 10.1158/0008-5472.CAN-13-3339. Epub 2014 Dec 15.

29.

Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis.

Zhou Y, Peng H, Sun H, Peng X, Tang C, Gan Y, Chen X, Mathur A, Hu B, Slade MD, Montgomery RR, Shaw AC, Homer RJ, White ES, Lee CM, Moore MW, Gulati M, Lee CG, Elias JA, Herzog EL.

Sci Transl Med. 2014 Jun 11;6(240):240ra76. doi: 10.1126/scitranslmed.3007096.

30.

CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung.

Peng X, Moore MW, Peng H, Sun H, Gan Y, Homer RJ, Herzog EL.

Front Pharmacol. 2014 May 16;5:80. doi: 10.3389/fphar.2014.00080. eCollection 2014.

31.

Review: interstitial lung disease associated with systemic sclerosis and idiopathic pulmonary fibrosis: how similar and distinct?

Herzog EL, Mathur A, Tager AM, Feghali-Bostwick C, Schneider F, Varga J.

Arthritis Rheumatol. 2014 Aug;66(8):1967-78. doi: 10.1002/art.38702. Review. No abstract available.

32.

MMP28 and macrophage polarization: orchestrating the attack of the mac.

Gan Y, Herzog EL.

J Leukoc Biol. 2014 Jan;95(1):1-3. doi: 10.1189/jlb.0813423. No abstract available.

PMID:
24385575
33.

Fibroblast engraftment in the decellularized mouse lung occurs via a β1-integrin-dependent, FAK-dependent pathway that is mediated by ERK and opposed by AKT.

Sun H, Calle E, Chen X, Mathur A, Zhu Y, Mendez J, Zhao L, Niklason L, Peng X, Peng H, Herzog EL.

Am J Physiol Lung Cell Mol Physiol. 2014 Mar 15;306(6):L463-75. doi: 10.1152/ajplung.00100.2013. Epub 2013 Dec 13.

34.

Targeting interleukin-13 with tralokinumab attenuates lung fibrosis and epithelial damage in a humanized SCID idiopathic pulmonary fibrosis model.

Murray LA, Zhang H, Oak SR, Coelho AL, Herath A, Flaherty KR, Lee J, Bell M, Knight DA, Martinez FJ, Sleeman MA, Herzog EL, Hogaboam CM.

Am J Respir Cell Mol Biol. 2014 May;50(5):985-94. doi: 10.1165/rcmb.2013-0342OC.

35.

Regulation and Relevance of Myofibroblast Responses in Idiopathic Pulmonary Fibrosis.

Moore MW, Herzog EL.

Curr Pathobiol Rep. 2013 Sep;1(3):199-208.

36.

Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2.

He CH, Lee CG, Dela Cruz CS, Lee CM, Zhou Y, Ahangari F, Ma B, Herzog EL, Rosenberg SA, Li Y, Nour AM, Parikh CR, Schmidt I, Modis Y, Cantley L, Elias JA.

Cell Rep. 2013 Aug 29;4(4):830-41. doi: 10.1016/j.celrep.2013.07.032. Epub 2013 Aug 22. Erratum in: Cell Rep. 2015 Mar 3;10(8):1433. Cell Rep. 2013 Nov 27;5(4):1156.

37.

Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis.

Reilkoff RA, Peng H, Murray LA, Peng X, Russell T, Montgomery R, Feghali-Bostwick C, Shaw A, Homer RJ, Gulati M, Mathur A, Elias JA, Herzog EL.

Am J Respir Crit Care Med. 2013 Jan 15;187(2):180-8. doi: 10.1164/rccm.201206-1109OC. Epub 2012 Dec 6.

38.

Editorial: Sticking it to fibrocytes with serum amyloid P.

Mathur A, Herzog EL.

J Leukoc Biol. 2012 Oct;92(4):693-4. doi: 10.1189/jlb.0412183. No abstract available.

PMID:
23028111
39.

Interstitial lung disease: is interstitial lung disease the same as scleroderma lung disease?

Murray LA, Rubinowitz A, Herzog EL.

Curr Opin Rheumatol. 2012 Nov;24(6):656-62. Review.

PMID:
22955020
40.

Flow cytometric identification of fibrocytes in scleroderma lung disease.

Russell TM, Herzog EL, Bucala R.

Methods Mol Biol. 2012;900:327-46. doi: 10.1007/978-1-60761-720-4_16.

PMID:
22933077
41.

Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-β1 signaling.

Lee CG, Herzog EL, Ahangari F, Zhou Y, Gulati M, Lee CM, Peng X, Feghali-Bostwick C, Jimenez SA, Varga J, Elias JA.

J Immunol. 2012 Sep 1;189(5):2635-44. doi: 10.4049/jimmunol.1201115. Epub 2012 Jul 23.

42.

Fibrocytes: emerging effector cells in chronic inflammation.

Peng H, Herzog EL.

Curr Opin Pharmacol. 2012 Aug;12(4):491-6. doi: 10.1016/j.coph.2012.03.002. Epub 2012 Mar 30. Review.

43.

Fibrocytes: emerging effector cells in chronic inflammation.

Reilkoff RA, Bucala R, Herzog EL.

Nat Rev Immunol. 2011 Jun;11(6):427-35. doi: 10.1038/nri2990. Epub 2011 May 20.

44.

Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosis.

Peng X, Mathai SK, Murray LA, Russell T, Reilkoff R, Chen Q, Gulati M, Elias JA, Bucala R, Gan Y, Herzog EL.

Fibrogenesis Tissue Repair. 2011 May 17;4(1):12. doi: 10.1186/1755-1536-4-12.

45.

Pirfenidone treatment of idiopathic pulmonary fibrosis.

Gan Y, Herzog EL, Gomer RH.

Ther Clin Risk Manag. 2011 Feb 8;7:39-47. doi: 10.2147/TCRM.S12209.

46.

TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P.

Murray LA, Chen Q, Kramer MS, Hesson DP, Argentieri RL, Peng X, Gulati M, Homer RJ, Russell T, van Rooijen N, Elias JA, Hogaboam CM, Herzog EL.

Int J Biochem Cell Biol. 2011 Jan;43(1):154-62. doi: 10.1016/j.biocel.2010.10.013. Epub 2010 Oct 29.

PMID:
21044893
47.

Recent advances in pulmonary fibrosis: implications for scleroderma.

Homer RJ, Herzog EL.

Curr Opin Rheumatol. 2010 Nov;22(6):683-9. doi: 10.1097/BOR.0b013e32833ddcc9. Review.

PMID:
20693906
48.

Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype.

Mathai SK, Gulati M, Peng X, Russell TR, Shaw AC, Rubinowitz AN, Murray LA, Siner JM, Antin-Ozerkis DE, Montgomery RR, Reilkoff RA, Bucala RJ, Herzog EL.

Lab Invest. 2010 Jun;90(6):812-23. doi: 10.1038/labinvest.2010.73. Epub 2010 Apr 19.

49.

Fibrocytes in health and disease.

Herzog EL, Bucala R.

Exp Hematol. 2010 Jul;38(7):548-56. doi: 10.1016/j.exphem.2010.03.004. Epub 2010 Mar 18. Review.

50.

Serum amyloid P therapeutically attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages.

Murray LA, Rosada R, Moreira AP, Joshi A, Kramer MS, Hesson DP, Argentieri RL, Mathai S, Gulati M, Herzog EL, Hogaboam CM.

PLoS One. 2010 Mar 12;5(3):e9683. doi: 10.1371/journal.pone.0009683.

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