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Items: 1 to 50 of 308

1.

Fifteen years of the cologne medical model study course: has the expectation of increasing student interest in general practice specialization been fulfilled?

Zims H, Karay Y, Neugebauer P, Herzig S, Stosch C.

GMS J Med Educ. 2019 Oct 15;36(5):Doc58. doi: 10.3205/zma001266. eCollection 2019.

2.

Antipsychotics and the Risk of Mortality or Cardiopulmonary Arrest in Hospitalized Adults.

Basciotta M, Zhou W, Ngo L, Donnino M, Marcantonio ER, Herzig SJ.

J Am Geriatr Soc. 2019 Nov 19. doi: 10.1111/jgs.16246. [Epub ahead of print]

PMID:
31743435
3.

Risk Factors for Severe Opioid-Related Adverse Events in a National Cohort of Medical Hospitalizations.

Herzig SJ, Stefan MS, Pekow PS, Shieh MS, Soares W, Raghunathan K, Lindenauer PK.

J Gen Intern Med. 2019 Nov 14. doi: 10.1007/s11606-019-05490-w. [Epub ahead of print]

PMID:
31728892
4.

Mitocellular communication: Shaping health and disease.

Mottis A, Herzig S, Auwerx J.

Science. 2019 Nov 15;366(6467):827-832. doi: 10.1126/science.aax3768. Epub 2019 Nov 14. Review.

PMID:
31727828
5.

Direct, gabapentin-insensitive interaction of a soluble form of the calcium channel subunit α2δ-1 with thrombospondin-4.

El-Awaad E, Pryymachuk G, Fried C, Matthes J, Isensee J, Hucho T, Neiss WF, Paulsson M, Herzig S, Zaucke F, Pietsch M.

Sci Rep. 2019 Nov 7;9(1):16272. doi: 10.1038/s41598-019-52655-y.

6.

The glucocorticoid receptor in brown adipocytes is dispensable for control of energy homeostasis.

Glantschnig C, Mattijssen F, Vogl ES, Ali Khan A, Rios Garcia M, Fischer K, Müller T, Uhlenhaut H, Nawroth P, Scheideler M, Rose AJ, Pellegata N, Herzig S.

EMBO Rep. 2019 Nov 5;20(11):e48552. doi: 10.15252/embr.201948552. Epub 2019 Sep 26.

PMID:
31559673
7.

Feasibility of neurochemically profiling mouse embryonic brain and its development in utero using 1 H MRS at 14.1 T.

Lei H, Montessuit S, Herzig S, Martinou JC.

NMR Biomed. 2019 Nov;32(11):e4163. doi: 10.1002/nbm.4163. Epub 2019 Aug 19.

PMID:
31424145
8.

Comparison of CRISPR Genomic Tagging for Affinity Purification and Endogenous Immunoprecipitation Coupled with Quantitative Mass Spectrometry To Identify the Dynamic AMPKα2 Interactome.

Stein BD, Herzig S, Martínez-Bartolomé S, Lavallée-Adam M, Shaw RJ, Yates JR 3rd.

J Proteome Res. 2019 Oct 4;18(10):3703-3714. doi: 10.1021/acs.jproteome.9b00378. Epub 2019 Sep 6.

PMID:
31398040
9.

Pain in the United States: Time for a Culture Shift in Expectations, Messaging, and Management.

Loh FE, Herzig SJ.

J Hosp Med. 2019 Dec 1;14(12):787-788. doi: 10.12788/jhm.3277. Epub 2019 Jul 24. No abstract available.

PMID:
31339835
10.

The role of brown and beige adipose tissue in glycaemic control.

Klepac K, Georgiadi A, Tschöp M, Herzig S.

Mol Aspects Med. 2019 Aug;68:90-100. doi: 10.1016/j.mam.2019.07.001. Epub 2019 Jul 16. Review.

PMID:
31283940
11.

Potentially Inappropriate Use of Intravenous Opioids in Hospitalized Patients.

Moore AB, Navarrett S, Herzig SJ.

J Hosp Med. 2019 Nov 1;14(10):678-680. doi: 10.12788/jhm.3225. Epub 2019 Jun 19.

PMID:
31251152
12.

Managing Acute Pain in the Hospital in the Face of the Opioid Crisis.

Herzig SJ.

Ann Intern Med. 2019 May 7;170(9):666. doi: 10.7326/L19-0052. No abstract available.

PMID:
31060065
13.

"Hopefully, I will never forget that again" - sensitizing medical students for drug safety by working on cases and simulating doctor-patient communication.

Kirsch V, Johannsen W, Thrien C, Herzig S, Matthes J.

GMS J Med Educ. 2019 Mar 15;36(2):Doc17. doi: 10.3205/zma001225. eCollection 2019.

14.

Energy metabolism in cachexia.

Rohm M, Zeigerer A, Machado J, Herzig S.

EMBO Rep. 2019 Apr;20(4). pii: e47258. doi: 10.15252/embr.201847258. Epub 2019 Mar 19. Review.

PMID:
30890538
15.

Single-Channel Resolution of the Interaction between C-Terminal CaV1.3 Isoforms and Calmodulin.

Kuzmenkina E, Novikova E, Jangsangthong W, Matthes J, Herzig S.

Biophys J. 2019 Mar 5;116(5):836-846. doi: 10.1016/j.bpj.2019.01.025. Epub 2019 Feb 1.

PMID:
30773296
16.

Endocannabinoid Signalling in Atherosclerosis and Related Metabolic Complications.

Guillamat-Prats R, Rami M, Herzig S, Steffens S.

Thromb Haemost. 2019 Apr;119(4):567-575. doi: 10.1055/s-0039-1678738. Epub 2019 Feb 15. Review.

PMID:
30769363
17.

A miR-29a-driven negative feedback loop regulates peripheral glucocorticoid receptor signaling.

Glantschnig C, Koenen M, Gil-Lozano M, Karbiener M, Pickrahn I, Williams-Dautovich J, Patel R, Cummins CL, Giroud M, Hartleben G, Vogl E, Blüher M, Tuckermann J, Uhlenhaut H, Herzig S, Scheideler M.

FASEB J. 2019 May;33(5):5924-5941. doi: 10.1096/fj.201801385RR. Epub 2019 Feb 11.

PMID:
30742779
18.

Preventability of Early Versus Late Hospital Readmissions.

Graham KL, Auerbach AD, Herzig SJ.

Ann Intern Med. 2019 Feb 5;170(3):219-220. doi: 10.7326/L18-0611. No abstract available.

PMID:
30716751
19.

Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD.

Garcia D, Hellberg K, Chaix A, Wallace M, Herzig S, Badur MG, Lin T, Shokhirev MN, Pinto AFM, Ross DS, Saghatelian A, Panda S, Dow LE, Metallo CM, Shaw RJ.

Cell Rep. 2019 Jan 2;26(1):192-208.e6. doi: 10.1016/j.celrep.2018.12.036.

20.

Cancer Cachexia: More Than Skeletal Muscle Wasting.

Schmidt SF, Rohm M, Herzig S, Berriel Diaz M.

Trends Cancer. 2018 Dec;4(12):849-860. doi: 10.1016/j.trecan.2018.10.001. Epub 2018 Oct 24. Review.

PMID:
30470306
21.

Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models.

Eichner LJ, Brun SN, Herzig S, Young NP, Curtis SD, Shackelford DB, Shokhirev MN, Leblanc M, Vera LI, Hutchins A, Ross DS, Shaw RJ, Svensson RU.

Cell Metab. 2019 Feb 5;29(2):285-302.e7. doi: 10.1016/j.cmet.2018.10.005. Epub 2018 Nov 8.

PMID:
30415923
22.

Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis.

Wolff G, Taranko AE, Meln I, Weinmann J, Sijmonsma T, Lerch S, Heide D, Billeter AT, Tews D, Krunic D, Fischer-Posovszky P, Müller-Stich BP, Herzig S, Grimm D, Heikenwälder M, Kao WW, Vegiopoulos A.

Mol Metab. 2019 Jan;19:97-106. doi: 10.1016/j.molmet.2018.10.007. Epub 2018 Oct 23.

23.

Norepinephrine triggers an immediate-early regulatory network response in primary human white adipocytes.

Higareda-Almaraz JC, Karbiener M, Giroud M, Pauler FM, Gerhalter T, Herzig S, Scheideler M.

BMC Genomics. 2018 Nov 3;19(1):794. doi: 10.1186/s12864-018-5173-0.

24.

Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice.

Görgülü K, Diakopoulos KN, Ai J, Schoeps B, Kabacaoglu D, Karpathaki AF, Ciecielski KJ, Kaya-Aksoy E, Ruess DA, Berninger A, Kowalska M, Stevanovic M, Wörmann SM, Wartmann T, Zhao Y, Halangk W, Voronina S, Tepikin A, Schlitter AM, Steiger K, Artati A, Adamski J, Aichler M, Walch A, Jastroch M, Hartleben G, Mantzoros CS, Weichert W, Schmid RM, Herzig S, Krüger A, Sainz B Jr, Lesina M, Algül H.

Gastroenterology. 2019 Jan;156(1):203-217.e20. doi: 10.1053/j.gastro.2018.09.053. Epub 2018 Oct 6.

PMID:
30296435
25.

Reply to "In Reference to 'Improving the Safety of Opioid Use for Acute Noncancer Pain in Hospitalized Adults: A Consensus Statement from the Society of Hospital Medicine'".

Herzig SJ, Mosher HJ, Calcaterra SL, Nuckols TK.

J Hosp Med. 2018 Sep;13(10):728. doi: 10.12788/jhm.3058. No abstract available.

PMID:
30261091
26.

Web Exclusive. Annals for Hospitalists Inpatient Notes - Managing Acute Pain in the Hospital in the Face of the Opioid Crisis.

Herzig SJ.

Ann Intern Med. 2018 Sep 18;169(6):HO2-HO3. doi: 10.7326/M18-2295. No abstract available.

PMID:
30242421
27.

Development of perceived pharmacological deficits of medical students and alumni supports claim for continuous and more application-oriented education.

Johannsen W, Frings B, Herzig S, Matthes J.

Naunyn Schmiedebergs Arch Pharmacol. 2019 Jan;392(1):29-36. doi: 10.1007/s00210-018-1563-8. Epub 2018 Sep 7.

PMID:
30194456
28.

Comparative Secretome Analyses of Primary Murine White and Brown Adipocytes Reveal Novel Adipokines.

Ali Khan A, Hansson J, Weber P, Foehr S, Krijgsveld J, Herzig S, Scheideler M.

Mol Cell Proteomics. 2018 Dec;17(12):2358-2370. doi: 10.1074/mcp.RA118.000704. Epub 2018 Aug 22.

29.

De novo NAD+ biosynthetic impairment in acute kidney injury in humans.

Poyan Mehr A, Tran MT, Ralto KM, Leaf DE, Washco V, Messmer J, Lerner A, Kher A, Kim SH, Khoury CC, Herzig SJ, Trovato ME, Simon-Tillaux N, Lynch MR, Thadhani RI, Clish CB, Khabbaz KR, Rhee EP, Waikar SS, Berg AH, Parikh SM.

Nat Med. 2018 Sep;24(9):1351-1359. doi: 10.1038/s41591-018-0138-z. Epub 2018 Aug 20.

30.

Longitudinal Trends and Variation in Antipsychotic Use in Older Adults After Cardiac Surgery.

Kim DH, Mahesri M, Bateman BT, Huybrechts KF, Inouye SK, Marcantonio ER, Herzig SJ, Ely EW, Pisani MA, Levin R, Avorn J.

J Am Geriatr Soc. 2018 Aug;66(8):1491-1498. doi: 10.1111/jgs.15418. Epub 2018 Aug 19.

31.

Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors.

Bayindir-Buchhalter I, Wolff G, Lerch S, Sijmonsma T, Schuster M, Gronych J, Billeter AT, Babaei R, Krunic D, Ketscher L, Spielmann N, Hrabe de Angelis M, Ruas JL, Müller-Stich BP, Heikenwalder M, Lichter P, Herzig S, Vegiopoulos A.

EMBO Mol Med. 2018 Aug;10(8). pii: e8613. doi: 10.15252/emmm.201708613.

32.

Alternative Splicing at N Terminus and Domain I Modulates CaV1.2 Inactivation and Surface Expression.

Bartels P, Yu D, Huang H, Hu Z, Herzig S, Soong TW.

Biophys J. 2018 Jul 3;115(1):163. doi: 10.1016/j.bpj.2018.06.001. No abstract available.

33.

Dietary protein dilution limits dyslipidemia in obesity through FGF21-driven fatty acid clearance.

Maida A, Zota A, Vegiopoulos A, Appak-Baskoy S, Augustin HG, Heikenwalder M, Herzig S, Rose AJ.

J Nutr Biochem. 2018 Jul;57:189-196. doi: 10.1016/j.jnutbio.2018.03.027. Epub 2018 Apr 7.

PMID:
29751292
34.

Alternative Splicing at N Terminus and Domain I Modulates CaV1.2 Inactivation and Surface Expression.

Bartels P, Yu D, Huang H, Hu Z, Herzig S, Soong TW.

Biophys J. 2018 May 8;114(9):2095-2106. doi: 10.1016/j.bpj.2018.03.029. Erratum in: Biophys J. 2018 Jul 3;115(1):163.

35.

Preventability of Early Versus Late Hospital Readmissions in a National Cohort of General Medicine Patients.

Graham KL, Auerbach AD, Schnipper JL, Flanders SA, Kim CS, Robinson EJ, Ruhnke GW, Thomas LR, Kripalani S, Vasilevskis EE, Fletcher GS, Sehgal NJ, Lindenauer PK, Williams MV, Metlay JP, Davis RB, Yang J, Marcantonio ER, Herzig SJ.

Ann Intern Med. 2018 Jun 5;168(11):766-774. doi: 10.7326/M17-1724. Epub 2018 May 1. Erratum in: Ann Intern Med. 2019 Jan 1;170(1):80.

36.

Jak-TGFβ cross-talk links transient adipose tissue inflammation to beige adipogenesis.

Babaei R, Schuster M, Meln I, Lerch S, Ghandour RA, Pisani DF, Bayindir-Buchhalter I, Marx J, Wu S, Schoiswohl G, Billeter AT, Krunic D, Mauer J, Lee YH, Granneman JG, Fischer L, Müller-Stich BP, Amri EZ, Kershaw EE, Heikenwälder M, Herzig S, Vegiopoulos A.

Sci Signal. 2018 Apr 24;11(527). pii: eaai7838. doi: 10.1126/scisignal.aai7838.

PMID:
29692363
37.

Improving the Safety of Opioid Use for Acute Noncancer Pain in Hospitalized Adults: A Consensus Statement From the Society of Hospital Medicine.

Herzig SJ, Mosher HJ, Calcaterra SL, Jena AB, Nuckols TK.

J Hosp Med. 2018 Apr;13(4):263-271. doi: 10.12788/jhm.2980.

38.

Safe Opioid Prescribing for Acute Noncancer Pain in Hospitalized Adults: A Systematic Review of Existing Guidelines.

Herzig SJ, Calcaterra SL, Mosher HJ, Ronan MV, Groningen NV, Shek L, Loffredo A, Keller M, Jena AB, Nuckols TK.

J Hosp Med. 2018 Apr;13(4):256-262. doi: 10.12788/jhm.2979.

39.

Effects of the Reactive Metabolite Methylglyoxal on Cellular Signalling, Insulin Action and Metabolism - What We Know in Mammals and What We Can Learn From Yeast.

Zemva J, Pfaff D, Groener JB, Fleming T, Herzig S, Teleman A, Nawroth PP, Tyedmers J.

Exp Clin Endocrinol Diabetes. 2019 Apr;127(4):203-214. doi: 10.1055/s-0043-122382. Epub 2018 Feb 8. Review.

PMID:
29421830
40.

High-glucose toxicity is mediated by AICAR-transformylase/IMP cyclohydrolase and mitigated by AMP-activated protein kinase in Caenorhabditis elegans.

Riedinger C, Mendler M, Schlotterer A, Fleming T, Okun J, Hammes HP, Herzig S, Nawroth PP.

J Biol Chem. 2018 Mar 30;293(13):4845-4859. doi: 10.1074/jbc.M117.805879. Epub 2018 Feb 2.

41.

Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart.

Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma TP, Herberich SE, Sauer SW, Poschet G, Federico G, Mogler C, Weis EM, Augustin HG, Yan M, Gretz N, Schmid RM, Adams RH, Gröne HJ, Hell R, Okun JG, Backs J, Nawroth PP, Herzig S, Fischer A.

Circulation. 2018 Jun 12;137(24):2592-2608. doi: 10.1161/CIRCULATIONAHA.117.029733. Epub 2018 Jan 20.

PMID:
29353241
42.

The Evaluation of Medical Inpatients Who Are Admitted on Long-term Opioid Therapy for Chronic Pain.

Mosher H, Herzig SJ, Danovitch I, Boutsicaris C, Hassamal S, Wittnebel K, Dashti A, Nuckols T.

J Hosp Med. 2018 Apr;13(4):249-255. doi: 10.12788/jhm.2889. Epub 2017 Dec 6. Review.

PMID:
29240853
43.

A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.

Lehmann LH, Jebessa ZH, Kreusser MM, Horsch A, He T, Kronlage M, Dewenter M, Sramek V, Oehl U, Krebs-Haupenthal J, von der Lieth AH, Schmidt A, Sun Q, Ritterhoff J, Finke D, Völkers M, Jungmann A, Sauer SW, Thiel C, Nickel A, Kohlhaas M, Schäfer M, Sticht C, Maack C, Gretz N, Wagner M, El-Armouche A, Maier LS, Londoño JEC, Meder B, Freichel M, Gröne HJ, Most P, Müller OJ, Herzig S, Furlong EEM, Katus HA, Backs J.

Nat Med. 2018 Jan;24(1):62-72. doi: 10.1038/nm.4452. Epub 2017 Dec 11.

PMID:
29227474
44.

Antipsychotics and the Risk of Aspiration Pneumonia in Individuals Hospitalized for Nonpsychiatric Conditions: A Cohort Study.

Herzig SJ, LaSalvia MT, Naidus E, Rothberg MB, Zhou W, Gurwitz JH, Marcantonio ER.

J Am Geriatr Soc. 2017 Dec;65(12):2580-2586. doi: 10.1111/jgs.15066. Epub 2017 Nov 2.

45.

The Diagnostic Yield of Noninvasive Microbiologic Sputum Sampling in a Cohort of Patients with Clinically Diagnosed Hospital-Acquired Pneumonia.

Naidus EL, Lasalvia MT, Marcantonio ER, Herzig SJ.

J Hosp Med. 2018 Jan 1;13(1):34-37. doi: 10.12788/jhm.2868. Epub 2017 Oct 18.

46.

Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence.

Rios Garcia M, Steinbauer B, Srivastava K, Singhal M, Mattijssen F, Maida A, Christian S, Hess-Stumpp H, Augustin HG, Müller-Decker K, Nawroth PP, Herzig S, Berriel Diaz M.

Cell Metab. 2017 Dec 5;26(6):842-855.e5. doi: 10.1016/j.cmet.2017.09.018. Epub 2017 Oct 19.

47.

Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.

Kumar V, Fleming T, Terjung S, Gorzelanny C, Gebhardt C, Agrawal R, Mall MA, Ranzinger J, Zeier M, Madhusudhan T, Ranjan S, Isermann B, Liesz A, Deshpande D, Häring HU, Biswas SK, Reynolds PR, Hammes HP, Peperkok R, Angel P, Herzig S, Nawroth PP.

Nucleic Acids Res. 2017 Oct 13;45(18):10595-10613. doi: 10.1093/nar/gkx705.

48.

AMPK: guardian of metabolism and mitochondrial homeostasis.

Herzig S, Shaw RJ.

Nat Rev Mol Cell Biol. 2018 Feb;19(2):121-135. doi: 10.1038/nrm.2017.95. Epub 2017 Oct 4. Review.

49.

Endocrine and autocrine/paracrine modulators of brown adipose tissue mass and activity as novel therapeutic strategies against obesity and type 2 diabetes.

Scheideler M, Herzig S, Georgiadi A.

Horm Mol Biol Clin Investig. 2017 Aug 29;31(2). pii: /j/hmbci.2017.31.issue-2/hmbci-2017-0043/hmbci-2017-0043.xml. doi: 10.1515/hmbci-2017-0043. Review.

PMID:
28850545
50.

Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux.

Zemva J, Fink CA, Fleming TH, Schmidt L, Loft A, Herzig S, Knieß RA, Mayer M, Bukau B, Nawroth PP, Tyedmers J.

Redox Biol. 2017 Oct;13:674-686. doi: 10.1016/j.redox.2017.08.007. Epub 2017 Aug 12.

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