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Items: 1 to 50 of 395

1.

Early Pro-inflammatory Microglia Activation After Inflammation-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Rats.

Serdar M, Kempe K, Rizazad M, Herz J, Bendix I, Felderhoff-Müser U, Sabir H.

Front Cell Neurosci. 2019 May 24;13:237. doi: 10.3389/fncel.2019.00237. eCollection 2019.

2.

Correction: Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System.

Liu Q, Zhang J, Zerbinatti C, Zhan Y, Kolber BJ, Herz J, Muglia LJ, Bu G.

PLoS Biol. 2019 Jun 4;17(6):e3000310. doi: 10.1371/journal.pbio.3000310. eCollection 2019 Jun.

3.

Tailoring Ultrafast Singlet Fission by the Chemical Modification of Phenazinothiadiazoles.

Alagna N, Han J, Wollscheid N, Lustres JLP, Herz J, Hahn S, Koser S, Paulus F, Bunz UHF, Dreuw A, Buckup T, Motzkus M.

J Am Chem Soc. 2019 Jun 5;141(22):8834-8845. doi: 10.1021/jacs.9b01079. Epub 2019 May 22.

PMID:
31063690
4.

LRP1 Deficiency in Vascular SMC Leads to Pulmonary Arterial Hypertension That Is Reversed by PPARγ Activation.

Calvier L, Boucher P, Herz J, Hansmann G.

Circ Res. 2019 Jun 7;124(12):1778-1785. doi: 10.1161/CIRCRESAHA.119.315088. Epub 2019 Apr 26.

PMID:
31023188
5.

Distal Dendritic Enrichment of HCN1 Channels in Hippocampal CA1 Is Promoted by Estrogen, but Does Not Require Reelin.

Meseke M, Neumüller F, Brunne B, Li X, Anstötz M, Pohlkamp T, Rogalla MM, Herz J, Rune GM, Bender RA.

eNeuro. 2018 Oct 15;5(5). pii: ENEURO.0258-18.2018. doi: 10.1523/ENEURO.0258-18.2018. eCollection 2018 Sep-Oct.

6.

Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer's disease.

Xian X, Pohlkamp T, Durakoglugil MS, Wong CH, Beck JK, Lane-Donovan C, Plattner F, Herz J.

Elife. 2018 Oct 30;7. pii: e40048. doi: 10.7554/eLife.40048.

7.

Adverse neuropsychiatric development following perinatal brain injury: from a preclinical perspective.

Bendix I, Hadamitzky M, Herz J, Felderhoff-Müser U.

Pediatr Res. 2019 Jan;85(2):198-215. doi: 10.1038/s41390-018-0222-6. Epub 2018 Oct 26. Review.

PMID:
30367160
8.

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.

Ma Q, Zhao Z, Sagare AP, Wu Y, Wang M, Owens NC, Verghese PB, Herz J, Holtzman DM, Zlokovic BV.

Mol Neurodegener. 2018 Oct 19;13(1):57. doi: 10.1186/s13024-018-0286-0.

9.

Morphological and Functional Analysis of CNS-Associated Lymphatics.

Herz J, Louveau A, Da Mesquita S, Kipnis J.

Methods Mol Biol. 2018;1846:141-151. doi: 10.1007/978-1-4939-8712-2_9.

PMID:
30242757
10.

Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms.

Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, Ohazama A.

PLoS One. 2018 Sep 20;13(9):e0204126. doi: 10.1371/journal.pone.0204126. eCollection 2018.

11.

CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature.

Louveau A, Herz J, Alme MN, Salvador AF, Dong MQ, Viar KE, Herod SG, Knopp J, Setliff JC, Lupi AL, Da Mesquita S, Frost EL, Gaultier A, Harris TH, Cao R, Hu S, Lukens JR, Smirnov I, Overall CC, Oliver G, Kipnis J.

Nat Neurosci. 2018 Oct;21(10):1380-1391. doi: 10.1038/s41593-018-0227-9. Epub 2018 Sep 17.

12.

Peripheral T Cell Depletion by FTY720 Exacerbates Hypoxic-Ischemic Brain Injury in Neonatal Mice.

Herz J, Köster C, Crasmöller M, Abberger H, Hansen W, Felderhoff-Müser U, Bendix I.

Front Immunol. 2018 Aug 6;9:1696. doi: 10.3389/fimmu.2018.01696. eCollection 2018.

13.

How We Can Rebuild Trust in Science-And Why We Must.

Boele-Woelki K, Francisco JS, Hahn U, Herz J.

Angew Chem Int Ed Engl. 2018 Oct 15;57(42):13696-13697. doi: 10.1002/anie.201805342. Epub 2018 Jul 24.

PMID:
30039913
14.

Author Correction: Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation.

Abou-Jaoude A, Badiqué L, Mlih M, Awan S, Guo S, Lemle A, Abboud C, Foppolo S, Host L, Terrand J, Justiniano H, Herz J, Matz RL, Boucher P.

Sci Rep. 2018 Jun 19;8(1):9577. doi: 10.1038/s41598-018-27564-1.

15.

Low-density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression.

Hamlin AN, Chinnarasu S, Ding Y, Xian X, Herz J, Jaeschke A, Hui DY.

J Biol Chem. 2018 Jun 22;293(25):9674-9684. doi: 10.1074/jbc.RA118.001952. Epub 2018 May 11.

16.

Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain Injury.

Doeppner TR, Herz J, Bähr M, Tonchev AB, Stoykova A.

Mol Neurobiol. 2019 Jan;56(1):567-582. doi: 10.1007/s12035-018-1104-y. Epub 2018 May 11.

PMID:
29748916
17.

Protection of Oligodendrocytes Through Neuronal Overexpression of the Small GTPase Ras in Hyperoxia-Induced Neonatal Brain Injury.

Serdar M, Herz J, Kempe K, Winterhager E, Jastrow H, Heumann R, Felderhoff-Müser U, Bendix I.

Front Neurol. 2018 Mar 21;9:175. doi: 10.3389/fneur.2018.00175. eCollection 2018.

18.

Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation.

Abou-Jaoude A, Badiqué L, Mlih M, Awan S, Guo S, Lemle A, Abboud C, Foppolo S, Host L, Terrand J, Justiniano H, Herz J, Matz RL, Boucher P.

Sci Rep. 2018 Mar 14;8(1):4501. doi: 10.1038/s41598-018-22819-3. Erratum in: Sci Rep. 2018 Jun 19;8(1):9577.

19.

Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF-RANKL signaling.

Bartelt A, Behler-Janbeck F, Beil FT, Koehne T, Müller B, Schmidt T, Heine M, Ochs L, Yilmaz T, Dietrich M, Tuckermann JP, Amling M, Herz J, Schinke T, Heeren J, Niemeier A.

Bone Res. 2018 Feb 26;6:4. doi: 10.1038/s41413-017-0006-3. eCollection 2018.

20.

Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium.

Sacharidou A, Chambliss KL, Ulrich V, Salmon JE, Shen YM, Herz J, Hui DY, Terada LS, Shaul PW, Mineo C.

Blood. 2018 May 10;131(19):2097-2110. doi: 10.1182/blood-2017-11-814681. Epub 2018 Mar 2.

21.

Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity.

Ye R, Gordillo R, Shao M, Onodera T, Chen Z, Chen S, Lin X, SoRelle JA, Li X, Tang M, Keller MP, Kuliawat R, Attie AD, Gupta RK, Holland WL, Beutler B, Herz J, Scherer PE.

J Clin Invest. 2018 Mar 1;128(3):1178-1189. doi: 10.1172/JCI97702. Epub 2018 Feb 19.

22.

Interaction between hypothermia and delayed mesenchymal stem cell therapy in neonatal hypoxic-ischemic brain injury.

Herz J, Köster C, Reinboth BS, Dzietko M, Hansen W, Sabir H, van Velthoven C, Bendix I, Felderhoff-Müser U.

Brain Behav Immun. 2018 May;70:118-130. doi: 10.1016/j.bbi.2018.02.006. Epub 2018 Feb 14.

23.

LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis.

Xian X, Ding Y, Dieckmann M, Zhou L, Plattner F, Liu M, Parks JS, Hammer RE, Boucher P, Tsai S, Herz J.

Elife. 2017 Nov 16;6. pii: e29292. doi: 10.7554/eLife.29292.

24.

Building a better blood-brain barrier.

Lane-Donovan C, Herz J.

Elife. 2017 Oct 10;6. pii: e31808. doi: 10.7554/eLife.31808.

25.

Imaging Subcellular Dynamics with Fast and Light-Efficient Volumetrically Parallelized Microscopy.

Dean KM, Roudot P, Welf ES, Pohlkamp T, Garrelts G, Herz J, Fiolka R.

Optica. 2017 Feb 20;4(2):263-271. doi: 10.1364/OPTICA.4.000263.

26.

Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency.

Evers BM, Rodriguez-Navas C, Tesla RJ, Prange-Kiel J, Wasser CR, Yoo KS, McDonald J, Cenik B, Ravenscroft TA, Plattner F, Rademakers R, Yu G, White CL 3rd, Herz J.

Cell Rep. 2017 Sep 12;20(11):2565-2574. doi: 10.1016/j.celrep.2017.08.056.

27.

Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia.

She A, Kurtser I, Reis SA, Hennig K, Lai J, Lang A, Zhao WN, Mazitschek R, Dickerson BC, Herz J, Haggarty SJ.

Cell Chem Biol. 2017 Jul 20;24(7):892-906.e5. doi: 10.1016/j.chembiol.2017.06.010. Epub 2017 Jul 14.

28.

Effects of Poly(ADP-Ribose) Polymerase-1 Inhibition in a Neonatal Rodent Model of Hypoxic-Ischemic Injury.

Klöfers M, Kohaut J, Bendix I, Herz J, Boos V, Felderhoff-Müser U, Dzietko M.

Biomed Res Int. 2017;2017:2924848. doi: 10.1155/2017/2924848. Epub 2017 Jun 15.

29.

Myeloid Cells in the Central Nervous System.

Herz J, Filiano AJ, Smith A, Yogev N, Kipnis J.

Immunity. 2017 Jun 20;46(6):943-956. doi: 10.1016/j.immuni.2017.06.007. Review.

30.

NGP 555, a γ-Secretase Modulator, Lowers the Amyloid Biomarker, Aβ42, in Cerebrospinal Fluid while Preventing Alzheimer's Disease Cognitive Decline in Rodents.

Kounnas MZ, Lane-Donovan C, Nowakowski DW, Herz J, Comer WT.

Alzheimers Dement (N Y). 2017 Jan;3(1):65-73. doi: 10.1016/j.trci.2016.09.003.

31.

A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease.

PrabhuDas MR, Baldwin CL, Bollyky PL, Bowdish DME, Drickamer K, Febbraio M, Herz J, Kobzik L, Krieger M, Loike J, McVicker B, Means TK, Moestrup SK, Post SR, Sawamura T, Silverstein S, Speth RC, Telfer JC, Thiele GM, Wang XY, Wright SD, El Khoury J.

J Immunol. 2017 May 15;198(10):3775-3789. doi: 10.4049/jimmunol.1700373.

32.

Sildenafil Enhances Quantity of Immature Neurons and Promotes Functional Recovery in the Developing Ischemic Mouse Brain.

Engels J, Elting N, Braun L, Bendix I, Herz J, Felderhoff-Müser U, Dzietko M.

Dev Neurosci. 2017;39(1-4):287-297. doi: 10.1159/000457832. Epub 2017 Mar 25.

PMID:
28343223
33.

News on the molecular regulation and function of hepatic low-density lipoprotein receptor and LDLR-related protein 1.

van de Sluis B, Wijers M, Herz J.

Curr Opin Lipidol. 2017 Jun;28(3):241-247. doi: 10.1097/MOL.0000000000000411. Review.

34.

Functional Roles of the Interaction of APP and Lipoprotein Receptors.

Pohlkamp T, Wasser CR, Herz J.

Front Mol Neurosci. 2017 Mar 1;10:54. doi: 10.3389/fnmol.2017.00054. eCollection 2017. Review.

35.

The ApoE receptors Vldlr and Apoer2 in central nervous system function and disease.

Lane-Donovan C, Herz J.

J Lipid Res. 2017 Jun;58(6):1036-1043. doi: 10.1194/jlr.R075507. Epub 2017 Mar 14. Review.

36.

Influenza A induces dysfunctional immunity and death in MeCP2-overexpressing mice.

Cronk JC, Herz J, Kim TS, Louveau A, Moser EK, Sharma AK, Smirnov I, Tung KS, Braciale TJ, Kipnis J.

JCI Insight. 2017 Jan 26;2(2):e88257. doi: 10.1172/jci.insight.88257.

37.

ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease.

Lane-Donovan C, Herz J.

Trends Endocrinol Metab. 2017 Apr;28(4):273-284. doi: 10.1016/j.tem.2016.12.001. Epub 2017 Jan 2. Review.

38.

Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses.

Wasser CR, Herz J.

J Biol Chem. 2017 Jan 27;292(4):1330-1338. doi: 10.1074/jbc.R116.766782. Epub 2016 Dec 19. Review.

39.

Ephrin Bs and canonical Reelin signalling.

Pohlkamp T, Xiao L, Sultana R, Bepari A, Bock HH, Henkemeyer M, Herz J.

Nature. 2016 Nov 24;539(7630):E4-E6. doi: 10.1038/nature20129. No abstract available.

40.

Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells.

Kraehling JR, Chidlow JH, Rajagopal C, Sugiyama MG, Fowler JW, Lee MY, Zhang X, Ramírez CM, Park EJ, Tao B, Chen K, Kuruvilla L, Larriveé B, Folta-Stogniew E, Ola R, Rotllan N, Zhou W, Nagle MW, Herz J, Williams KJ, Eichmann A, Lee WL, Fernández-Hernando C, Sessa WC.

Nat Commun. 2016 Nov 21;7:13516. doi: 10.1038/ncomms13516.

41.

Mesenchymal stem cell-derived extracellular vesicles ameliorate inflammation-induced preterm brain injury.

Drommelschmidt K, Serdar M, Bendix I, Herz J, Bertling F, Prager S, Keller M, Ludwig AK, Duhan V, Radtke S, de Miroschedji K, Horn PA, van de Looij Y, Giebel B, Felderhoff-Müser U.

Brain Behav Immun. 2017 Feb;60:220-232. doi: 10.1016/j.bbi.2016.11.011. Epub 2016 Nov 12.

42.

FE65 and FE65L1 share common synaptic functions and genetically interact with the APP family in neuromuscular junction formation.

Strecker P, Ludewig S, Rust M, Mundinger TA, Görlich A, Krächan EG, Mehrfeld C, Herz J, Korte M, Guénette SY, Kins S.

Sci Rep. 2016 May 11;6:25652. doi: 10.1038/srep25652.

43.

Dendritic cells tip the balance towards induction of regulatory T cells upon priming in experimental autoimmune encephalomyelitis.

Paterka M, Voss JO, Werr J, Reuter E, Franck S, Leuenberger T, Herz J, Radbruch H, Bopp T, Siffrin V, Zipp F.

J Autoimmun. 2017 Jan;76:108-114. doi: 10.1016/j.jaut.2016.09.008. Epub 2016 Oct 2.

PMID:
27707650
44.

Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice.

Lane-Donovan C, Wong WM, Durakoglugil MS, Wasser CR, Jiang S, Xian X, Herz J.

J Neurosci. 2016 Sep 28;36(39):10141-50. doi: 10.1523/JNEUROSCI.1054-16.2016. Epub 2016 Sep 28.

45.

Expression of a recombinant full-length LRP1B receptor in human non-small cell lung cancer cells confirms the postulated growth-suppressing function of this large LDL receptor family member.

Beer AG, Zenzmaier C, Schreinlechner M, Haas J, Dietrich MF, Herz J, Marschang P.

Oncotarget. 2016 Oct 18;7(42):68721-68733. doi: 10.18632/oncotarget.11897.

46.

Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system.

Konradt C, Ueno N, Christian DA, Delong JH, Pritchard GH, Herz J, Bzik DJ, Koshy AA, McGavern DB, Lodoen MB, Hunter CA.

Nat Microbiol. 2016 Feb 15;1:16001. doi: 10.1038/nmicrobiol.2016.1.

47.

Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain Injury.

Hoeber D, Sifringer M, van de Looij Y, Herz J, Sizonenko SV, Kempe K, Serdar M, Palasz J, Hadamitzky M, Endesfelder S, Fandrey J, Felderhoff-Müser U, Bendix I.

Oxid Med Cell Longev. 2016;2016:9247493. doi: 10.1155/2016/9247493. Epub 2016 Jul 14.

48.

Prosaposin is a regulator of progranulin levels and oligomerization.

Nicholson AM, Finch NA, Almeida M, Perkerson RB, van Blitterswijk M, Wojtas A, Cenik B, Rotondo S, Inskeep V, Almasy L, Dyer T, Peralta J, Jun G, Wood AR, Frayling TM, Fuchsberger C, Fowler S, Teslovich TM, Manning AK, Kumar S, Curran J, Lehman D, Abecasis G, Duggirala R, Pottier C, Zahir HA, Crook JE, Karydas A, Mitic L, Sun Y, Dickson DW, Bu G, Herz J, Yu G, Miller BL, Ferguson S, Petersen RC, Graff-Radford N, Blangero J, Rademakers R.

Nat Commun. 2016 Jun 30;7:11992. doi: 10.1038/ncomms11992.

49.

Endogenous hypothermic response to hypoxia reduces brain injury: Implications for modeling hypoxic-ischemic encephalopathy and therapeutic hypothermia in neonatal mice.

Reinboth BS, Köster C, Abberger H, Prager S, Bendix I, Felderhoff-Müser U, Herz J.

Exp Neurol. 2016 Sep;283(Pt A):264-75. doi: 10.1016/j.expneurol.2016.06.024. Epub 2016 Jun 25.

50.

Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis.

Ding Y, Xian X, Holland WL, Tsai S, Herz J.

EBioMedicine. 2016 May;7:135-45. doi: 10.1016/j.ebiom.2016.04.002. Epub 2016 Apr 4.

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