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Items: 24


Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs.

Hollingsworth SA, Kelly B, Valant C, Michaelis JA, Mastromihalis O, Thompson G, Venkatakrishnan AJ, Hertig S, Scammells PJ, Sexton PM, Felder CC, Christopoulos A, Dror RO.

Nat Commun. 2019 Jul 23;10(1):3289. doi: 10.1038/s41467-019-11062-7.


Novel peptide probes to assess the tensional state of fibronectin fibers in cancer.

Arnoldini S, Moscaroli A, Chabria M, Hilbert M, Hertig S, Schibli R, Béhé M, Vogel V.

Nat Commun. 2017 Nov 27;8(1):1793. doi: 10.1038/s41467-017-01846-0.


Revealing Atomic-Level Mechanisms of Protein Allostery with Molecular Dynamics Simulations.

Hertig S, Latorraca NR, Dror RO.

PLoS Comput Biol. 2016 Jun 10;12(6):e1004746. doi: 10.1371/journal.pcbi.1004746. eCollection 2016 Jun. Review.


'The lesser of two evils…' - views of persons with rheumatoid arthritis on medication adherence: a qualitative study.

Brandstetter S, Hertig S, Loss J, Ehrenstein B, Apfelbacher C.

Psychol Health. 2016 Jun;31(6):675-92. doi: 10.1080/08870446.2016.1139111. Epub 2016 Feb 2.


Multidomain Assembler (MDA) Generates Models of Large Multidomain Proteins.

Hertig S, Goddard TD, Johnson GT, Ferrin TE.

Biophys J. 2015 May 5;108(9):2097-102. doi: 10.1016/j.bpj.2015.03.051.


A guide to the visual analysis and communication of biomolecular structural data.

Johnson GT, Hertig S.

Nat Rev Mol Cell Biol. 2014 Oct;15(10):690-8. doi: 10.1038/nrm3874. Epub 2014 Sep 23. Review.


'Doctor, what would you do in my position?' Health professionals and the decision-making process in pregnancy monitoring.

Hertig SG, Cavalli S, Burton-Jeangros C, Elger BS.

J Med Ethics. 2014 May;40(5):310-4. doi: 10.1136/medethics-2012-100887. Epub 2013 Mar 29.


Catch bonds.

Hertig S, Vogel V.

Curr Biol. 2012 Oct 9;22(19):R823-5. doi: 10.1016/j.cub.2012.08.035. No abstract available.


Probing the Structure and Dynamics of Proteins by Combining Molecular Dynamics Simulations and Experimental NMR Data.

Allison JR, Hertig S, Missimer JH, Smith LJ, Steinmetz MO, Dolenc J.

J Chem Theory Comput. 2012 Oct 9;8(10):3430-44. doi: 10.1021/ct300393b. Epub 2012 Jul 30.


Engineering mechanosensitive multivalent receptor-ligand interactions: why the nanolinker regions of bacterial adhesins matter.

Hertig S, Chabria M, Vogel V.

Nano Lett. 2012 Oct 10;12(10):5162-8. doi: 10.1021/nl302153h. Epub 2012 Sep 14.


Stretching fibronectin fibres disrupts binding of bacterial adhesins by physically destroying an epitope.

Chabria M, Hertig S, Smith ML, Vogel V.

Nat Commun. 2010;1:135. doi: 10.1038/ncomms1135.


Epirubicin exhibits potent anti-tumor activity in an animal model of malignant glioma when administered via controlled-release polymers.

Recinos VR, Bekelis K, Ziegler SG, Vick D, Hertig S, Tyler BM, Li KW, Kosztowski T, Legnani FG, Brem H, Olivi A.

J Neurooncol. 2010 Mar;97(1):1-10. doi: 10.1007/s11060-009-9984-3. Epub 2009 Aug 20.


Automated fiber tracking of human brain white matter using diffusion tensor imaging.

Zhang W, Olivi A, Hertig SJ, van Zijl P, Mori S.

Neuroimage. 2008 Aug 15;42(2):771-7. doi: 10.1016/j.neuroimage.2008.04.241. Epub 2008 Apr 30.


Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human.

Bossen C, Ingold K, Tardivel A, Bodmer JL, Gaide O, Hertig S, Ambrose C, Tschopp J, Schneider P.

J Biol Chem. 2006 May 19;281(20):13964-71. Epub 2006 Mar 17.


Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex.

Holler N, Tardivel A, Kovacsovics-Bankowski M, Hertig S, Gaide O, Martinon F, Tinel A, Deperthes D, Calderara S, Schulthess T, Engel J, Schneider P, Tschopp J.

Mol Cell Biol. 2003 Feb;23(4):1428-40.


Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).

Schneider P, Olson D, Tardivel A, Browning B, Lugovskoy A, Gong D, Dobles M, Hertig S, Hofmann K, Van Vlijmen H, Hsu YM, Burkly LC, Tschopp J, Zheng TS.

J Biol Chem. 2003 Feb 14;278(7):5444-54. Epub 2002 Dec 3.


Mutations leading to X-linked hypohidrotic ectodermal dysplasia affect three major functional domains in the tumor necrosis factor family member ectodysplasin-A.

Schneider P, Street SL, Gaide O, Hertig S, Tardivel A, Tschopp J, Runkel L, Alevizopoulos K, Ferguson BM, Zonana J.

J Biol Chem. 2001 Jun 1;276(22):18819-27. Epub 2001 Mar 14.


A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth.

Rennert P, Schneider P, Cachero TG, Thompson J, Trabach L, Hertig S, Holler N, Qian F, Mullen C, Strauch K, Browning JL, Ambrose C, Tschopp J.

J Exp Med. 2000 Dec 4;192(11):1677-84.


Granzyme A is an interleukin 1 beta-converting enzyme.

Irmler M, Hertig S, MacDonald HR, Sadoul R, Becherer JD, Proudfoot A, Solari R, Tschopp J.

J Exp Med. 1995 May 1;181(5):1917-22.


Macrophage precursor cells produce perforin and perform Yac-1 lytic activity in response to stimulation with interleukin-2.

Li H, Pohler U, Strehlow I, Hertig S, Baccarini M, Emmendörffer A, Tschopp J, Lohmann-Matthes ML.

J Leukoc Biol. 1994 Aug;56(2):117-23.


Secretion of bioactive granulocyte-macrophage colony-stimulating factor by human colorectal carcinoma cells.

Lahm H, Wyniger J, Hertig S, Yilmaz A, Fischer JR, Givel JC, Odartchenko N.

Cancer Res. 1994 Jul 15;54(14):3700-2.


Clusterin, the human apolipoprotein and complement inhibitor, binds to complement C7, C8 beta, and the b domain of C9.

Tschopp J, Chonn A, Hertig S, French LE.

J Immunol. 1993 Aug 15;151(4):2159-65.


Human megakaryocytes express clusterin and package it without apolipoprotein A-1 into alpha-granules.

Tschopp J, Jenne DE, Hertig S, Preissner KT, Morgenstern H, Sapino AP, French L.

Blood. 1993 Jul 1;82(1):118-25.


Inhibition of lymphocyte mediated cytotoxicity by perforin antisense oligonucleotides.

Acha-Orbea H, Scarpellino L, Hertig S, Dupuis M, Tschopp J.

EMBO J. 1990 Dec;9(12):3815-9.

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