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Items: 12

1.

Discovery of small molecule antagonists of chemokine receptor CXCR6 that arrest tumor growth in SK-HEP-1 mouse xenografts as a model of hepatocellular carcinoma.

Peddibhotla S, Hershberger PM, Jason Kirby R, Sugarman E, Maloney PR, Hampton Sessions E, Divlianska D, Morfa CJ, Terry D, Pinkerton AB, Smith LH, Malany S.

Bioorg Med Chem Lett. 2020 Feb 15;30(4):126899. doi: 10.1016/j.bmcl.2019.126899. Epub 2019 Dec 17.

PMID:
31882297
2.

Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress.

Kirby RJ, Divlianska DB, Whig K, Bryan N, Morfa CJ, Koo A, Nguyen KH, Maloney P, Peddibhotla S, Sessions EH, Hershberger PM, Smith LH, Malany S.

J Pharmacol Exp Ther. 2018 Jan;364(1):87-96. doi: 10.1124/jpet.117.243717. Epub 2017 Nov 3. Erratum in: J Pharmacol Exp Ther. 2018 Feb;364(2):179.

PMID:
29101218
3.

Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes.

Peddibhotla S, Fontaine P, Leung CK, Maloney P, Hershberger PM, Wang Y, Bousquet MS, Luesch H, Mangravita-Novo A, Pinkerton AB, Smith LH, Malany S, Choe K.

ACS Chem Biol. 2015 Aug 21;10(8):1871-9. doi: 10.1021/acschembio.5b00304. Epub 2015 May 22.

PMID:
25946346
4.

Inhibitors of Myocyte Triacylglyceride Accumulation.

Hershberger PM, Sugarman E, Maloney P, Peddibhotla S, Koo A, Suyama E, Ruidiaz ME, Heynen-Genel S, Nguyen KH, Vasile S, Mangravita-Novo A, Smith LH, Soundarapandian MM, Salaniwal S, Kung P, Vega RB, Chung TDY, Pinkerton AB, Malany S, Kelly DP.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Dec 15 [updated 2015 Feb 11].

5.

A high throughput screen for inhibitors of nematode detoxification genes.

Peddibhotla S, Leung CK, Maloney P, Hershberger PM, Nguyen K, Vasile S, Suyama E, Kane A, Bousquet MS, Leusch H, Stonich D, Mangravita-Novo A, Salaniwal S, Kung P, Diwan J, Smith LH, Chung TDY, Pinkerton AB, Malany S, Choe K.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Apr 11 [updated 2014 Jan 13].

6.

Probing the CXCR6/CXCL16 Axis: Targeting Prevention of Prostate Cancer Metastasis.

Hershberger PM, Peddibhotla S, Sugarman E, Maloney P, Key D, Suyama E, Nguyen K, Vasile S, Kraft M, Stonich D, Mangravita-Novo A, Vicchiarelli M, Gosalia P, Milewski M, Li L, Hedrick M, Sun Q, Sergienko E, Cheltsov A, Salanawil S, Diwan J, Smith LH, Taichman RS, Chung TDY, Pinkerton AB, Malany S, Roth GP.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Dec 15 [updated 2014 May 13].

7.

Imidazole-derived agonists for the neurotensin 1 receptor.

Hershberger PM, Hedrick MP, Peddibhotla S, Mangravita-Novo A, Gosalia P, Li Y, Gray W, Vicchiarelli M, Smith LH, Chung TD, Thomas JB, Caron MG, Pinkerton AB, Barak LS, Roth GP.

Bioorg Med Chem Lett. 2014 Jan 1;24(1):262-7. doi: 10.1016/j.bmcl.2013.11.026. Epub 2013 Nov 21.

8.

Synthesis and physicochemical characterization of novel phenotypic probes targeting the nuclear factor-kappa B signaling pathway.

Hershberger PM, Peddibhotla S, Sessions EH, Divlianska DB, Correa RG, Pinkerton AB, Reed JC, Roth GP.

Beilstein J Org Chem. 2013 May 8;9:900-7. doi: 10.3762/bjoc.9.103. Print 2013.

9.

Development of a quantitative structure-activity relationship model for inhibition of gram-positive bacterial cell growth by biarylamides.

Stanton DT, Madhav PJ, Wilson LJ, Morris TW, Hershberger PM, Parker CN.

J Chem Inf Comput Sci. 2004 Jan-Feb;44(1):221-9.

PMID:
14741031
10.

The identification and characterization of hydrazinyl urea-based antibacterial agents through combinatorial chemistry.

Wilson LJ, Morris TW, Wu Q, Renick PJ, Parker CN, Davis MC, McKeever HD, Hershberger PM, Switzer AG, Shrum G, Sunder S, Jones DR, Soper SS, Dobson RL, Burt T, Morand KL, Stella M.

Bioorg Med Chem Lett. 2001 May 7;11(9):1149-52.

PMID:
11354364
11.

Concept, design, and preclinical evaluation of quinolonyl lactam antibacterials.

Hershberger PM, Demuth TP Jr.

Adv Exp Med Biol. 1998;456:239-67. Review. No abstract available.

PMID:
10549372
12.

Preparation and antimicrobial assessment of 2-thioether-linked quinolonyl-carbapenems.

Hershberger PM, Switzer AG, Yelm KE, Coleman MC, Devries CA, Rourke FJ, Davis BW, Kraft WG, Twinem TL, Koenigs PM, Paule SM, Siehnel RJ, Zoutendam PH, Imbus R, Demuth TP Jr.

J Antibiot (Tokyo). 1998 Sep;51(9):857-71.

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