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Validation of a Food Frequency Questionnaire to Assess Intake of n-3 Polyunsaturated Fatty Acids in Switzerland.

Herter-Aeberli I, Graf C, Vollenweider A, Häberling I, Srikanthan P, Hersberger M, Berger G, Mathis D.

Nutrients. 2019 Aug 10;11(8). pii: E1863. doi: 10.3390/nu11081863.


Lipid Emulsion Containing High Amounts of n3 Fatty Acids (Omegaven) as Opposed to n6 Fatty Acids (Intralipid) Preserves Insulin Signaling and Glucose Uptake in Perfused Rat Hearts.

Lou PH, Lucchinetti E, Hersberger M, Clanachan AS, Zaugg M.

Anesth Analg. 2019 Jun 24. doi: 10.1213/ANE.0000000000004295. [Epub ahead of print]


The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis.

Wyss A, Raselli T, Perkins N, Ruiz F, Schmelczer G, Klinke G, Moncsek A, Roth R, Spalinger MR, Hering L, Atrott K, Lang S, Frey-Wagner I, Mertens JC, Scharl M, Sailer AW, Pabst O, Hersberger M, Pot C, Rogler G, Misselwitz B.

Mucosal Immunol. 2019 May;12(3):733-745. doi: 10.1038/s41385-019-0140-x. Epub 2019 Feb 11.


Liberal fluid fasting: impact on gastric pH and residual volume in healthy children undergoing general anaesthesia for elective surgery.

Schmidt AR, Buehler KP, Both C, Wiener R, Klaghofer R, Hersberger M, Weiss M, Schmitz A.

Br J Anaesth. 2018 Sep;121(3):647-655. doi: 10.1016/j.bja.2018.02.065. Epub 2018 May 3.


Risk factor analysis for a complicated postoperative course after neonatal arterial switch operation: The role of troponin T.

Christmann M, Wipf A, Dave H, Quandt D, Niesse O, Deisenberg M, Hersberger M, Kretschmar O, Knirsch W.

Congenit Heart Dis. 2018 Jul;13(4):594-601. doi: 10.1111/chd.12615. Epub 2018 Jul 17.


Effects of 6 Weeks of Parenteral Cobalamin Supplementation on Clinical and Biochemical Variables in Cats with Gastrointestinal Disease.

Kempf J, Hersberger M, Melliger RH, Reusch CE, Kook PH.

J Vet Intern Med. 2017 Nov;31(6):1664-1672. doi: 10.1111/jvim.14830. Epub 2017 Sep 12.


Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats.

Lou PH, Lucchinetti E, Scott KY, Huang Y, Gandhi M, Hersberger M, Clanachan AS, Lemieux H, Zaugg M.

Physiol Rep. 2017 Aug;5(16). pii: e13388. doi: 10.14814/phy2.13388.


Paediatric Laboratory Medicine - Some reflections on the sub-specialty.

Grey VL, Loh TP, Metz M, Lang T, Hersberger M.

Clin Biochem. 2017 Aug;50(12):648-650. doi: 10.1016/j.clinbiochem.2017.04.005. Epub 2017 Apr 11. No abstract available.


The value of plasma vitamin B6 profiles in early onset epileptic encephalopathies.

Mathis D, Abela L, Albersen M, Bürer C, Crowther L, Beese K, Hartmann H, Bok LA, Struys E, Papuc SM, Rauch A, Hersberger M, Verhoeven-Duif NM, Plecko B.

J Inherit Metab Dis. 2016 Sep;39(5):733-741. doi: 10.1007/s10545-016-9955-8. Epub 2016 Jun 24.


Clinical phenotype, biochemical profile, and treatment in 19 patients with arginase 1 deficiency.

Huemer M, Carvalho DR, Brum JM, Ünal Ö, Coskun T, Weisfeld-Adams JD, Schrager NL, Scholl-Bürgi S, Schlune A, Donner MG, Hersberger M, Gemperle C, Riesner B, Ulmer H, Häberle J, Karall D.

J Inherit Metab Dis. 2016 May;39(3):331-340. doi: 10.1007/s10545-016-9928-y. Epub 2016 Apr 1.


Resolvin D1 Polarizes Primary Human Macrophages toward a Proresolution Phenotype through GPR32.

Schmid M, Gemperle C, Rimann N, Hersberger M.

J Immunol. 2016 Apr 15;196(8):3429-37. doi: 10.4049/jimmunol.1501701. Epub 2016 Mar 11.


Effects of Steroid Hormones on Sex Differences in Cerebral Perfusion.

Ghisleni C, Bollmann S, Biason-Lauber A, Poil SS, Brandeis D, Martin E, Michels L, Hersberger M, Suckling J, Klaver P, O'Gorman RL.

PLoS One. 2015 Sep 10;10(9):e0135827. doi: 10.1371/journal.pone.0135827. eCollection 2015.


Diagnostic performance of S100B protein serum measurement in detecting intracranial injury in children with mild head trauma.

Manzano S, Holzinger IB, Kellenberger CJ, Lacroix L, Klima-Lange D, Hersberger M, La Scala G, Altermatt S, Staubli G.

Emerg Med J. 2016 Jan;33(1):42-6. doi: 10.1136/emermed-2014-204513. Epub 2015 Aug 17.


Gender-Related Differences in Patients Presenting with Suspected Acute Coronary Syndromes: Clinical Presentation, Biomarkers and Diagnosis.

Stähli BE, Gebhard C, Yonekawa K, Gebhard CE, Altwegg LA, von Eckardstein A, Hersberger M, Novopashenny I, Wolters R, Wischnewsky MB, Lüscher TF, Maier W.

Cardiology. 2015;132(3):189-98. doi: 10.1159/000435908. Epub 2015 Aug 13.


LC-MS/MS based assay and reference intervals in children and adolescents for oxysterols elevated in Niemann-Pick diseases.

Klinke G, Rohrbach M, Giugliani R, Burda P, Baumgartner MR, Tran C, Gautschi M, Mathis D, Hersberger M.

Clin Biochem. 2015 Jun;48(9):596-602. doi: 10.1016/j.clinbiochem.2015.03.007. Epub 2015 Mar 25.


ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.

Herová M, Schmid M, Gemperle C, Hersberger M.

J Immunol. 2015 Mar 1;194(5):2330-7. doi: 10.4049/jimmunol.1402166. Epub 2015 Jan 30.


Genetic associations with coronary heart disease: meta-analyses of 12 candidate genetic variants.

Hersberger M.

Gene. 2015 Mar 10;558(2):299. doi: 10.1016/j.gene.2015.01.017. Epub 2015 Jan 13. No abstract available.


Propofol (Diprivan®) and Intralipid® exacerbate insulin resistance in type-2 diabetic hearts by impairing GLUT4 trafficking.

Lou PH, Lucchinetti E, Zhang L, Affolter A, Gandhi M, Zhakupova A, Hersberger M, Hornemann T, Clanachan AS, Zaugg M.

Anesth Analg. 2015 Feb;120(2):329-40. doi: 10.1213/ANE.0000000000000558.


G-protein receptor kinase 4 polymorphism and response to antihypertensive therapy.

Muskalla AM, Suter PM, Saur M, Nowak A, Hersberger M, Krayenbuehl PA.

Clin Chem. 2014 Dec;60(12):1543-8. doi: 10.1373/clinchem.2014.226605. Epub 2014 Oct 9.


Loss of Intralipid®- but not sevoflurane-mediated cardioprotection in early type-2 diabetic hearts of fructose-fed rats: importance of ROS signaling.

Lou PH, Lucchinetti E, Zhang L, Affolter A, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi HF, Clanachan AS, Zaugg M.

PLoS One. 2014 Aug 15;9(8):e104971. doi: 10.1371/journal.pone.0104971. eCollection 2014.


Clinical criteria replenish high-sensitive troponin and inflammatory markers in the stratification of patients with suspected acute coronary syndrome.

Stähli BE, Yonekawa K, Altwegg LA, Wyss C, Hof D, Fischbacher P, Brauchlin A, Schulthess G, Krayenbühl PA, von Eckardstein A, Hersberger M, Neidhart M, Gay S, Novopashenny I, Wolters R, Frank M, Wischnewsky MB, Lüscher TF, Maier W.

PLoS One. 2014 Jun 3;9(6):e98626. doi: 10.1371/journal.pone.0098626. eCollection 2014.


Low dose aspirin is associated with plasma chemerin levels and may reduce adipose tissue inflammation.

Herová M, Schmid M, Gemperle C, Loretz C, Hersberger M.

Atherosclerosis. 2014 Aug;235(2):256-62. doi: 10.1016/j.atherosclerosis.2014.05.912. Epub 2014 May 15.


Sugar-sweetened beverages with moderate amounts of fructose, but not sucrose, induce Fatty Acid synthesis in healthy young men: a randomized crossover study.

Hochuli M, Aeberli I, Weiss A, Hersberger M, Troxler H, Gerber PA, Spinas GA, Berneis K.

J Clin Endocrinol Metab. 2014 Jun;99(6):2164-72. doi: 10.1210/jc.2013-3856. Epub 2014 Mar 6.


The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases.

Lou PH, Lucchinetti E, Zhang L, Affolter A, Schaub MC, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi HF, Clanachan AS, Zaugg M.

PLoS One. 2014 Jan 30;9(1):e87205. doi: 10.1371/journal.pone.0087205. eCollection 2014.


Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat.

Warren BE, Lou PH, Lucchinetti E, Zhang L, Clanachan AS, Affolter A, Hersberger M, Zaugg M, Lemieux H.

Am J Physiol Endocrinol Metab. 2014 Mar;306(6):E658-67. doi: 10.1152/ajpendo.00511.2013. Epub 2014 Jan 14. Erratum in: Am J Physiol Endocrinol Metab. 2014 Dec 15;307(12):E1166.


Association of polymorphisms in the ALOX15B gene with coronary artery disease.

Wuest SJ, Horn T, Marti-Jaun J, Kühn H, Hersberger M.

Clin Biochem. 2014 Apr;47(6):349-55. doi: 10.1016/j.clinbiochem.2013.12.013. Epub 2013 Dec 27.


Antioxidant supplements reduced oxidative stress and stabilized liver function tests but did not reduce inflammation in a randomized controlled trial in obese children and adolescents.

Murer SB, Aeberli I, Braegger CP, Gittermann M, Hersberger M, Leonard SW, Taylor AW, Traber MG, Zimmermann MB.

J Nutr. 2014 Feb;144(2):193-201. doi: 10.3945/jn.113.185561. Epub 2013 Dec 18.


Fatty acid-induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis.

Freigang S, Ampenberger F, Weiss A, Kanneganti TD, Iwakura Y, Hersberger M, Kopf M.

Nat Immunol. 2013 Oct;14(10):1045-53. doi: 10.1038/ni.2704. Epub 2013 Sep 1.


High levels of anti-inflammatory and pro-resolving lipid mediators lipoxins and resolvins and declining docosahexaenoic acid levels in human milk during the first month of lactation.

Weiss GA, Troxler H, Klinke G, Rogler D, Braegger C, Hersberger M.

Lipids Health Dis. 2013 Jun 15;12:89. doi: 10.1186/1476-511X-12-89.


A VLP-based vaccine against interleukin-1α protects mice from atherosclerosis.

Tissot AC, Spohn G, Jennings GT, Shamshiev A, Kurrer MO, Windak R, Meier M, Viesti M, Hersberger M, Kündig TM, Ricci R, Bachmann MF.

Eur J Immunol. 2013 Mar;43(3):716-22. doi: 10.1002/eji.201242687. Epub 2013 Jan 28.


Regulation of the formyl peptide receptor 1 (FPR1) gene in primary human macrophages.

Gemperle C, Schmid M, Herova M, Marti-Jaun J, Wuest SJ, Loretz C, Hersberger M.

PLoS One. 2012;7(11):e50195. doi: 10.1371/journal.pone.0050195. Epub 2012 Nov 21.


Infarct-remodelled hearts with limited oxidative capacity boost fatty acid oxidation after conditioning against ischaemia/reperfusion injury.

Lou PH, Zhang L, Lucchinetti E, Heck M, Affolter A, Gandhi M, Kienesberger PC, Hersberger M, Clanachan AS, Zaugg M.

Cardiovasc Res. 2013 Feb 1;97(2):251-61. doi: 10.1093/cvr/cvs323. Epub 2012 Oct 24.


Expression and regulation of 12/15-lipoxygenases in human primary macrophages.

Wuest SJ, Crucet M, Gemperle C, Loretz C, Hersberger M.

Atherosclerosis. 2012 Nov;225(1):121-7. doi: 10.1016/j.atherosclerosis.2012.07.022. Epub 2012 Aug 23.


No evidence for the involvement of the lipoxin A4 receptor (FPR2/ALX ) gene in the susceptibility to coronary artery disease.

Waechter V, Marti-Jaun J, Weber A, Madi ZL, Hersberger M.

Clin Chem Lab Med. 2012 Jan;50(1):177-9. No abstract available.


TLR9 agonists induced cell death in Burkitt's lymphoma cells is variable and influenced by TLR9 polymorphism.

Noack J, Jordi M, Zauner L, Alessi D, Burch A, Tinguely M, Hersberger M, Bernasconi M, Nadal D.

Cell Death Dis. 2012 Jun 21;3:e323. doi: 10.1038/cddis.2012.60.


Lower plasma dehydroepiandrosterone concentration in the long term after severe accidental injury.

Oe M, Schnyder U, Schumacher S, Mueller-Pfeiffer C, Wilhelm FH, Kalebasi N, Roos D, Hersberger M, Martin-Soelch C.

Psychother Psychosom. 2012;81(2):121-3. doi: 10.1159/000330243. Epub 2012 Feb 2. No abstract available.


Characterization of the promoter and the transcriptional regulation of the lipoxin A4 receptor (FPR2/ALX) gene in human monocytes and macrophages.

Waechter V, Schmid M, Herova M, Weber A, Günther V, Marti-Jaun J, Wüst S, Rösinger M, Gemperle C, Hersberger M.

J Immunol. 2012 Feb 15;188(4):1856-67. doi: 10.4049/jimmunol.1101788. Epub 2012 Jan 13.


Dyslipidemias in children and adolescents.

Hersberger M.

Clin Biochem. 2011 May;44(7):507-8. doi: 10.1016/j.clinbiochem.2011.02.027. No abstract available.


Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis.

Freigang S, Ampenberger F, Spohn G, Heer S, Shamshiev AT, Kisielow J, Hersberger M, Yamamoto M, Bachmann MF, Kopf M.

Eur J Immunol. 2011 Jul;41(7):2040-51. doi: 10.1002/eji.201041316. Epub 2011 Jun 8.


Enhanced glucose uptake via GLUT4 fuels recovery from calcium overload after ischaemia-reperfusion injury in sevoflurane- but not propofol-treated hearts.

Lucchinetti E, Wang L, Ko KW, Troxler H, Hersberger M, Zhang L, Omar MA, Lopaschuk GD, Clanachan AS, Zaugg M.

Br J Anaesth. 2011 Jun;106(6):792-800. doi: 10.1093/bja/aer065. Epub 2011 Apr 6.


Plasma B-type natriuretic peptide levels in children with heart disease.

Knirsch W, Häusermann E, Fasnacht M, Hersberger M, Gessler P, Bauersfeld U.

Acta Paediatr. 2011 Sep;100(9):1213-6. doi: 10.1111/j.1651-2227.2011.02258.x. Epub 2011 Apr 12.


Association of STR polymorphisms in CMA1 and IL-4 with asthma and atopy: the SAPALDIA cohort.

Hersberger M, Thun GA, Imboden M, Brandstätter A, Waechter V, Summerer M, Schmid-Grendelmeier P, Bircher A, Rohrer L, Berger W, Russi EW, Rochat T, Kronenberg F, Probst-Hensch N.

Hum Immunol. 2010 Nov;71(11):1154-60. doi: 10.1016/j.humimm.2010.08.008. Epub 2010 Aug 22.


Deoxysphingoid bases as plasma markers in diabetes mellitus.

Bertea M, Rütti MF, Othman A, Marti-Jaun J, Hersberger M, von Eckardstein A, Hornemann T.

Lipids Health Dis. 2010 Aug 16;9:84. doi: 10.1186/1476-511X-9-84.


Metabolic profiling of hearts exposed to sevoflurane and propofol reveals distinct regulation of fatty acid and glucose oxidation: CD36 and pyruvate dehydrogenase as key regulators in anesthetic-induced fuel shift.

Wang L, Ko KW, Lucchinetti E, Zhang L, Troxler H, Hersberger M, Omar MA, Posse de Chaves EI, Lopaschuk GD, Clanachan AS, Zaugg M.

Anesthesiology. 2010 Sep;113(3):541-51. doi: 10.1097/ALN.0b013e3181e2c1a1.


Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: leukotrienes, lipoxins and resolvins.

Hersberger M.

Clin Chem Lab Med. 2010 Aug;48(8):1063-73. doi: 10.1515/CCLM.2010.212. Review.


Excellent agreement between genetic and hydrogen breath tests for lactase deficiency and the role of extended symptom assessment.

Pohl D, Savarino E, Hersberger M, Behlis Z, Stutz B, Goetze O, Eckardstein AV, Fried M, Tutuian R.

Br J Nutr. 2010 Sep;104(6):900-7. doi: 10.1017/S0007114510001297. Epub 2010 Apr 19.


Serum creatinine, cystatin C, and beta-trace protein in diagnostic staging and predicting progression of primary nondiabetic chronic kidney disease.

Spanaus KS, Kollerits B, Ritz E, Hersberger M, Kronenberg F, von Eckardstein A; Mild and Moderate Kidney Disease (MMKD) Study Group.

Clin Chem. 2010 May;56(5):740-9. doi: 10.1373/clinchem.2009.138826. Epub 2010 Mar 11.

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