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Items: 1 to 50 of 71

1.

Divergent Effects of Metformin on an Inflammatory Model of Parkinson's Disease.

Tayara K, Espinosa-Oliva AM, García-Domínguez I, Ismaiel AA, Boza-Serrano A, Deierborg T, Machado A, Herrera AJ, Venero JL, de Pablos RM.

Front Cell Neurosci. 2018 Nov 21;12:440. doi: 10.3389/fncel.2018.00440. eCollection 2018.

2.

Potential Use of Nanomedicine for the Anti-inflammatory Treatment of Neurodegenerative Diseases.

Cayero-Otero MD, Espinosa-Oliva AM, Herrera AJ, Garcia-Dominguez I, Fernandez-Arevalo M, Martin-Banderas L, de Pablos RM.

Curr Pharm Des. 2018;24(14):1589-1616. doi: 10.2174/1381612824666180403113015.

PMID:
29611482
3.

Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass.

Goh BC, Singhal V, Herrera AJ, Tomlinson RE, Kim S, Faugere MC, Germain-Lee EL, Clemens TL, Lee SJ, DiGirolamo DJ.

J Biol Chem. 2017 Aug 18;292(33):13809-13822. doi: 10.1074/jbc.M117.782128. Epub 2017 Jun 28.

4.

Caspase-8 inhibition represses initial human monocyte activation in septic shock model.

Oliva-Martin MJ, Sanchez-Abarca LI, Rodhe J, Carrillo-Jimenez A, Vlachos P, Herrera AJ, Garcia-Quintanilla A, Caballero-Velazquez T, Perez-Simon JA, Joseph B, Venero JL.

Oncotarget. 2016 Jun 21;7(25):37456-37470. doi: 10.18632/oncotarget.9648.

5.

Chronic stress alters the expression levels of longevity-related genes in the rat hippocampus.

Sánchez-Hidalgo AC, Muñoz MF, Herrera AJ, Espinosa-Oliva AM, Stowell R, Ayala A, Machado A, Venero JL, de Pablos RM.

Neurochem Int. 2016 Jul;97:181-92. doi: 10.1016/j.neuint.2016.04.009. Epub 2016 Apr 24.

PMID:
27120255
6.

Metformin, besides exhibiting strong in vivo anti-inflammatory properties, increases mptp-induced damage to the nigrostriatal dopaminergic system.

Ismaiel AA, Espinosa-Oliva AM, Santiago M, García-Quintanilla A, Oliva-Martín MJ, Herrera AJ, Venero JL, de Pablos RM.

Toxicol Appl Pharmacol. 2016 May 1;298:19-30. doi: 10.1016/j.taap.2016.03.004. Epub 2016 Mar 10.

PMID:
26971375
7.

The limitations of using risk factors to screen for blunt cerebrovascular injuries: the harder you look, the more you find.

Jacobson LE, Ziemba-Davis M, Herrera AJ.

World J Emerg Surg. 2015 Sep 26;10:46. doi: 10.1186/s13017-015-0040-7. eCollection 2015.

8.

Relevance of chronic stress and the two faces of microglia in Parkinson's disease.

Herrera AJ, Espinosa-Oliva AM, Carrillo-Jiménez A, Oliva-Martín MJ, García-Revilla J, García-Quintanilla A, de Pablos RM, Venero JL.

Front Cell Neurosci. 2015 Aug 14;9:312. doi: 10.3389/fncel.2015.00312. eCollection 2015. Review.

9.

Collateral Damage: Contribution of Peripheral Inflammation to Neurodegenerative Diseases.

Herrera AJ, Espinosa-Oliva AM, Oliva-Martin MJ, Carrillo-Jimenez A, Venero JL, de Pablos RM.

Curr Top Med Chem. 2015;15(21):2193-210. Review.

PMID:
26059357
10.

Chemoselective intramolecular functionalization of methyl groups in nonconstrained molecules promoted by N-iodosulfonamides.

Paz NR, Rodríguez-Sosa D, Valdés H, Marticorena R, Melián D, Copano MB, González CC, Herrera AJ.

Org Lett. 2015 May 15;17(10):2370-3. doi: 10.1021/acs.orglett.5b00866. Epub 2015 May 1.

PMID:
25932748
11.

Synergistic deleterious effect of chronic stress and sodium azide in the mouse hippocampus.

Delgado-Cortés MJ, Espinosa-Oliva AM, Sarmiento M, Argüelles S, Herrera AJ, Mauriño R, Villarán RF, Venero JL, Machado A, de Pablos RM.

Chem Res Toxicol. 2015 Apr 20;28(4):651-61. doi: 10.1021/tx5004408. Epub 2015 Feb 17.

PMID:
25658758
12.

Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism.

Viceconte N, Burguillos MA, Herrera AJ, De Pablos RM, Joseph B, Venero JL.

J Neuroinflammation. 2015 Jan 14;12:5. doi: 10.1186/s12974-014-0228-x.

13.

Chronic stress as a risk factor for Alzheimer's disease.

Machado A, Herrera AJ, de Pablos RM, Espinosa-Oliva AM, Sarmiento M, Ayala A, Venero JL, Santiago M, Villarán RF, Delgado-Cortés MJ, Argüelles S, Cano J.

Rev Neurosci. 2014;25(6):785-804. doi: 10.1515/revneuro-2014-0035. Review.

PMID:
25178904
14.

Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation.

de Pablos RM, Herrera AJ, Espinosa-Oliva AM, Sarmiento M, Muñoz MF, Machado A, Venero JL.

J Neuroinflammation. 2014 Feb 24;11:34. doi: 10.1186/1742-2094-11-34.

15.

Role of dopamine in the recruitment of immune cells to the nigro-striatal dopaminergic structures.

Espinosa-Oliva AM, de Pablos RM, Sarmiento M, Villarán RF, Carrillo-Jiménez A, Santiago M, Venero JL, Herrera AJ, Cano J, Machado A.

Neurotoxicology. 2014 Mar;41:89-101. doi: 10.1016/j.neuro.2014.01.006. Epub 2014 Jan 30.

PMID:
24486959
16.

Intracranial injection of LPS in rat as animal model of neuroinflammation.

Espinosa-Oliva AM, de Pablos RM, Herrera AJ.

Methods Mol Biol. 2013;1041:295-305. doi: 10.1007/978-1-62703-520-0_26.

PMID:
23813388
17.

Immunohistochemical detection of microglia.

de Pablos RM, Espinosa-Oliva AM, Herrera AJ.

Methods Mol Biol. 2013;1041:281-9. doi: 10.1007/978-1-62703-520-0_24.

PMID:
23813386
18.

Single-level transforaminal interbody fusion for traumatic lumbosacral fracture-dislocation: a case report.

Herrera AJ, Berry CA, Rao RD.

Acta Orthop Belg. 2013 Feb;79(1):117-22.

PMID:
23547528
19.

Cross-modulatory effects of clopidogrel and heparin on platelet and fibrin incorporation in thrombosis.

Cooley BC, Herrera AJ.

Blood Coagul Fibrinolysis. 2013 Sep;24(6):593-8. doi: 10.1097/MBC.0b013e3283602a03.

PMID:
23492917
20.

Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system.

Hernández-Romero MC, Delgado-Cortés MJ, Sarmiento M, de Pablos RM, Espinosa-Oliva AM, Argüelles S, Bández MJ, Villarán RF, Mauriño R, Santiago M, Venero JL, Herrera AJ, Cano J, Machado A.

Neurotoxicology. 2012 Jun;33(3):347-60. doi: 10.1016/j.neuro.2012.01.018. Epub 2012 Feb 6.

PMID:
22330755
21.

Peripheral inflammation increases the damage in animal models of nigrostriatal dopaminergic neurodegeneration: possible implication in Parkinson's disease incidence.

Machado A, Herrera AJ, Venero JL, Santiago M, De Pablos RM, Villarán RF, Espinosa-Oliva AM, Argüelles S, Sarmiento M, Delgado-Cortés MJ, Mauriño R, Cano J.

Parkinsons Dis. 2011;2011:393769. doi: 10.4061/2011/393769. Epub 2011 Apr 13.

22.

Inflammatory Animal Model for Parkinson's Disease: The Intranigral Injection of LPS Induced the Inflammatory Process along with the Selective Degeneration of Nigrostriatal Dopaminergic Neurons.

Machado A, Herrera AJ, Venero JL, Santiago M, de Pablos RM, Villarán RF, Espinosa-Oliva AM, Argüelles S, Sarmiento M, Delgado-Cortés MJ, Mauriño R, Cano J.

ISRN Neurol. 2011;2011:476158. doi: 10.5402/2011/476158. Epub 2011 Apr 17.

23.

Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson`s disease.

Villarán RF, Espinosa-Oliva AM, Sarmiento M, De Pablos RM, Argüelles S, Delgado-Cortés MJ, Sobrino V, Van Rooijen N, Venero JL, Herrera AJ, Cano J, Machado A.

J Neurochem. 2010 Sep;114(6):1687-700. doi: 10.1111/j.1471-4159.2010.06879.x. Epub 2010 Aug 19.

24.

Degeneration of dopaminergic neurons induced by thrombin injection in the substantia nigra of the rat is enhanced by dexamethasone: role of monoamine oxidase enzyme.

Argüelles S, Herrera AJ, Carreño-Müller E, de Pablos RM, Villarán RF, Espinosa-Oliva AM, Machado A, Cano J.

Neurotoxicology. 2010 Jan;31(1):55-66. doi: 10.1016/j.neuro.2009.12.001. Epub 2009 Dec 5.

PMID:
19969022
25.

The intranigral injection of tissue plasminogen activator induced blood-brain barrier disruption, inflammatory process and degeneration of the dopaminergic system of the rat.

Villarán RF, de Pablos RM, Argüelles S, Espinosa-Oliva AM, Tomás-Camardiel M, Herrera AJ, Cano J, Machado A.

Neurotoxicology. 2009 May;30(3):403-13. doi: 10.1016/j.neuro.2009.02.011. Epub 2009 Feb 25.

PMID:
19442825
26.

Intramolecular 1,8-hydrogen-atom transfer reactions in (1-->4)-O-disaccharide systems: conformational and stereochemical requirements.

Francisco CG, Herrera AJ, Kennedy AR, Martín A, Melián D, Pérez-Martín I, Quintanal LM, Suárez E.

Chemistry. 2008;14(33):10369-81. doi: 10.1002/chem.200801414.

PMID:
18830990
27.

Stereocontrolled photocyclization of 1,2-diketones: application of a 1,3-acetyl group transfer methodology to carbohydrates.

Herrera AJ, Rondón M, Suárez E.

J Org Chem. 2008 May 2;73(9):3384-91. doi: 10.1021/jo702663w. Epub 2008 Mar 28.

PMID:
18370422
28.

The intrastriatal injection of thrombin in rat induced a retrograde apoptotic degeneration of nigral dopaminergic neurons through synaptic elimination.

Herrera AJ, de Pablos RM, Carreño-Müller E, Villarán RF, Venero JL, Tomás-Camardiel M, Cano J, Machado A.

J Neurochem. 2008 May;105(3):750-62. doi: 10.1111/j.1471-4159.2007.05170.x. Epub 2007 Dec 6.

29.

Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production.

Villarán RF, Tomás-Camardiel M, de Pablos RM, Santiago M, Herrera AJ, Navarro A, Machado A, Cano J.

Neurotoxicology. 2008 Mar;29(2):244-58. Epub 2007 Nov 17.

PMID:
18093658
30.

Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide.

Hernández-Romero MC, Argüelles S, Villarán RF, de Pablos RM, Delgado-Cortés MJ, Santiago M, Herrera AJ, Cano J, Machado A.

J Neurochem. 2008 Apr;105(2):445-59. Epub 2007 Nov 28.

31.

Synthesis of a bicyclic analog of L-iduronic acid adopting the biologically relevant 2S0 conformation.

Herrera AJ, Beneitez MT, Amorim L, Cañada FJ, Jiménez-Barbero J, Sinaÿ P, Blériot Y.

Carbohydr Res. 2007 Sep 3;342(12-13):1876-87. Epub 2007 Feb 25.

PMID:
17359949
32.

Stress increases vulnerability to inflammation in the rat prefrontal cortex.

de Pablos RM, Villarán RF, Argüelles S, Herrera AJ, Venero JL, Ayala A, Cano J, Machado A.

J Neurosci. 2006 May 24;26(21):5709-19.

33.

Deprenyl enhances the striatal neuronal damage produced by quinolinic acid.

de Pablos RM, Herrera AJ, Tomás-Camardiel M, Machado A, Cano J.

Brain Res Mol Brain Res. 2005 Nov 18;141(1):48-57. Epub 2005 Oct 3.

PMID:
16202473
34.

Blood-brain barrier disruption highly induces aquaporin-4 mRNA and protein in perivascular and parenchymal astrocytes: protective effect by estradiol treatment in ovariectomized animals.

Tomás-Camardiel M, Venero JL, Herrera AJ, De Pablos RM, Pintor-Toro JA, Machado A, Cano J.

J Neurosci Res. 2005 Apr 15;80(2):235-46.

PMID:
15772982
35.

Dopamine-dependent neurotoxicity of lipopolysaccharide in substantia nigra.

De Pablos RM, Herrera AJ, Villarán RF, Cano J, Machado A.

FASEB J. 2005 Mar;19(3):407-9. Epub 2004 Dec 29.

PMID:
15625078
36.

Inflammatory process as a determinant factor for the degeneration of substantia nigra dopaminergic neurons.

Herrera AJ, Tomás-Camardiel M, Venero JL, Cano J, Machado A.

J Neural Transm (Vienna). 2005 Jan;112(1):111-9. Epub 2004 Mar 19. Review.

PMID:
15599609
37.
38.

Thrombin induces in vivo degeneration of nigral dopaminergic neurones along with the activation of microglia.

Carreño-Müller E, Herrera AJ, de Pablos RM, Tomás-Camardiel M, Venero JL, Cano J, Machado A.

J Neurochem. 2003 Mar;84(5):1201-14.

40.

Intramolecular 1,8-hydrogen abstraction between glucopyranose units in a disaccharide model promoted by alkoxy radicals.

Francisco CG, Herrera AJ, Kennedy AR, Melián D, Suárez E.

Angew Chem Int Ed Engl. 2002 Mar 1;41(5):856-8. No abstract available.

PMID:
12491359
42.

Differential regulation of glutamic acid decarboxylase mRNA and tyrosine hydroxylase mRNA expression in the aged manganese-treated rats.

Tomás-Camardiel M, Herrera AJ, Venero JL, Cruz Sánchez-Hidalgo M, Cano J, Machado A.

Brain Res Mol Brain Res. 2002 Jun 30;103(1-2):116-29.

PMID:
12106697
44.

Intramolecular 1,5- versus 1,6-hydrogen abstraction reaction promoted by alkoxy radicals in carbohydrate models.

Francisco CG, Freire R, Herrera AJ, Peréz-Martín I, Suárez E.

Org Lett. 2002 May 30;4(11):1959-61. Erratum in: Org Lett 2002 Sep 19;4(19):3337.

PMID:
12027657
45.

The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system.

Herrera AJ, Castaño A, Venero JL, Cano J, Machado A.

Neurobiol Dis. 2000 Aug;7(4):429-47.

PMID:
10964613
46.

Language bias discredits the peer-review system.

Herrera AJ.

Nature. 1999 Feb 11;397(6719):467. No abstract available.

PMID:
10028961
47.
48.

Low selenium diet increases the dopamine turnover in prefrontal cortex of the rat.

Castaño A, Ayala A, Rodríguez-Gómez JA, Herrera AJ, Cano J, Machado A.

Neurochem Int. 1997 Jun;30(6):549-55.

PMID:
9152996
50.

Ageing and monoamine turnover in the lateral geniculate nucleus and visual cortex of the rat.

Herrera AJ, Machado A, Cano J.

Neurochem Int. 1993 Jun;22(6):531-9.

PMID:
8513280

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