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Early tracheostomy after initiation of venovenous extracorporeal membrane oxygenation is associated with decreased duration of extracorporeal membrane oxygenation support.

DiChiacchio L, Boulos FM, Brigante F, Raithel M, Shah A, Pasrija C, Mackowick K, Menaker J, Mazzeffi M, Herr D, Kon ZN, Deatrick KB.

Perfusion. 2020 Feb 5:267659119898327. doi: 10.1177/0267659119898327. [Epub ahead of print]


Skin Cutibacterium acnes Mediates Fermentation to Suppress the Calcium Phosphate-Induced Itching: A Butyric Acid Derivative with Potential for Uremic Pruritus.

Keshari S, Wang Y, Herr DR, Wang SM, Yang WC, Chuang TH, Chen CL, Huang CM.

J Clin Med. 2020 Jan 22;9(2). pii: E312. doi: 10.3390/jcm9020312.


Cysteine-Capped Hydrogels Incorporating Copper as Effective Antimicrobial Materials against Methicillin-Resistant Staphylococcus aureus.

Yang JJ, Huang YC, Chuang TH, Herr DR, Hsieh MF, Huang CJ, Huang CM.

Microorganisms. 2020 Jan 21;8(2). pii: E149. doi: 10.3390/microorganisms8020149.


Evaluating the use of microelectrode array technology and cell-based neuronal culture models for proconvulsant risk assessment: progress from the HESI NeuTox consortium.

Millard DC, Nicolini AM, Arrowood CA, Hayes HB, Bradley JA, Strock CJ, Freudenrich TM, Wallace K, Shafer TJ, Cato MJ, Chaudhary KW, Saavedra L, Haag D, Feaster TK, Anson BD, Luerman G, Hess D, Shi Y, Li J, Shi H, Levesque P, Kreir M, Lu HR, Suzuki I, Odawara A, Miyamoto N, Ojima A, Kanda Y, Blinova K, Herr D, Roberts R, Pierson J.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.076. Epub 2019 Oct 17. No abstract available.


Sphingosine 1-Phosphate Receptor 2 Induces Otoprotective Responses to Cisplatin Treatment.

Wang W, Shanmugam MK, Xiang P, Yam TYA, Kumar V, Chew WS, Chang JK, Ali MZB, Reolo MJY, Peh YX, Karim SNBA, Tan AYY, Sanda T, Sethi G, Herr DR.

Cancers (Basel). 2020 Jan 15;12(1). pii: E211. doi: 10.3390/cancers12010211.


Ultrastructural Characteristics of DHA-Induced Pyroptosis.

Herr DR, Yam TYA, Tan WSD, Koh SS, Wong WSF, Ong WY, Chayaburakul K.

Neuromolecular Med. 2020 Jan 4. doi: 10.1007/s12017-019-08586-y. [Epub ahead of print]


Activation of sphingosine 1-phosphate receptor 2 attenuates chemotherapy-induced neuropathy.

Wang W, Xiang P, Chew WS, Torta F, Bandla A, Lopez V, Seow WL, Lam BWS, Chang JK, Wong P, Chayaburakul K, Ong WY, Wenk MR, Sundar R, Herr DR.

J Biol Chem. 2020 Jan 24;295(4):1143-1152. doi: 10.1074/jbc.RA119.011699. Epub 2019 Dec 27.


Generativity and other buffers of death awareness in first responders.

Herr DJ, Buchanan EM.

Anxiety Stress Coping. 2019 Nov 27:1-14. doi: 10.1080/10615806.2019.1695522. [Epub ahead of print]


Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer's disease mice.

Jew K, Herr D, Wong C, Kennell A, Morris-Schaffer K, Oberdörster G, O'Banion MK, Cory-Slechta DA, Elder A.

Part Fibre Toxicol. 2019 Nov 26;16(1):45. doi: 10.1186/s12989-019-0323-3.


Outcomes of Venovenous Extracorporeal Membrane Oxygenation When Stratified by Age: How Old Is Too Old?

Deatrick KB, Mazzeffi MA, Galvagno SM Jr, Tesoriero RB, Kaczoroswki DJ, Herr DL, Dolly K, Rabinowitz RP, Scalea TM, Menaker J.

ASAIO J. 2019 Nov 18. doi: 10.1097/MAT.0000000000001076. [Epub ahead of print]


Associations with metabolites in Chinese suggest new metabolic roles in Alzheimer's and Parkinson's diseases.

Chai JF, Raichur S, Khor IW, Torta F, Chew WS, Herr DR, Ching J, Kovalik JP, Khoo CM, Wenk MR, Tai ES, Sim X.

Hum Mol Genet. 2020 Jan 15;29(2):189-201. doi: 10.1093/hmg/ddz246.


Clinical utility of venoarterial-extracorporeal membrane oxygenation (VA-ECMO) in patients with drug-induced cardiogenic shock: a retrospective study of the Extracorporeal Life Support Organizations' ECMO case registry.

Weiner L, Mazzeffi MA, Hines EQ, Gordon D, Herr DL, Kim HK.

Clin Toxicol (Phila). 2019 Oct 16:1-6. doi: 10.1080/15563650.2019.1676896. [Epub ahead of print]


Design, Synthesis and Evaluation of New Indolylpyrimidylpiperazines for Gastrointestinal Cancer Therapy.

Tan A, Babak MV, Venkatesan G, Lim C, Klotz KN, Herr DR, Cheong SL, Federico S, Spalluto G, Ong WY, Chen YZ, Loo JSE, Pastorin G.

Molecules. 2019 Oct 11;24(20). pii: E3661. doi: 10.3390/molecules24203661.


High-efficiency, high-flux in-line hemofiltration using a high blood flow extracorporeal circuit.

Grazioli A, Shah SR, Rabin J, Shah R, Madathil RJ, King JD, DiChiacchio L, Rector RP, Deatrick KB, Wu ZJ, Herr DL.

Perfusion. 2019 Sep 16:267659119871232. doi: 10.1177/0267659119871232. [Epub ahead of print]


Influence of Patient's Age on the Outcome of Vaginal and Laparoscopic Procedures in Urogynaecology.

Joukhadar R, Radosa J, Paulus V, Hamza A, Solomayer EF, Herr D, Wöckel A, Baum S.

Geburtshilfe Frauenheilkd. 2019 Sep;79(9):949-958. doi: 10.1055/a-0854-5916. Epub 2019 May 22.


Butyric Acid from Probiotic Staphylococcus epidermidis in the Skin Microbiome Down-Regulates the Ultraviolet-Induced Pro-Inflammatory IL-6 Cytokine via Short-Chain Fatty Acid Receptor.

Keshari S, Balasubramaniam A, Myagmardoloonjin B, Herr DR, Negari IP, Huang CM.

Int J Mol Sci. 2019 Sep 11;20(18). pii: E4477. doi: 10.3390/ijms20184477.


Pleotropic Roles of Autotaxin in the Nervous System Present Opportunities for the Development of Novel Therapeutics for Neurological Diseases.

Herr DR, Chew WS, Satish RL, Ong WY.

Mol Neurobiol. 2020 Jan;57(1):372-392. doi: 10.1007/s12035-019-01719-1. Epub 2019 Jul 30. Review.


Echo is a good, not perfect, measure of cardiac output in critically ill surgical patients.

Olivieri PP, Patel R, Kolb S, Fatima S, Galvagno SM, Haase DJ, Ramani GV, Ludmir J, Alkhatib H, Herr D, Bruno DA, Scalea TM, Murthi SB.

J Trauma Acute Care Surg. 2019 Aug;87(2):379-385. doi: 10.1097/TA.0000000000002304.


The Role of Deconstructive Teaching in the Training of Laparoscopy.

Balafoutas D, Joukhadar R, Kiesel M, Häusler S, Loeb S, Woeckel A, Herr D.

JSLS. 2019 Apr-Jun;23(2). pii: e2019.00020. doi: 10.4293/JSLS.2019.00020.


Does chemotherapy improve survival in patients with nodal positive luminal A breast cancer? A retrospective Multicenter Study.

Herr D, Wischnewsky M, Joukhadar R, Chow O, Janni W, Leinert E, Fink V, Stüber T, Curtaz C, Kreienberg R, Blettner M, Wollschläger D, Wöckel A.

PLoS One. 2019 Jul 8;14(7):e0218434. doi: 10.1371/journal.pone.0218434. eCollection 2019.


Role of Renin-Angiotensin-System in Human Breast Cancer Cells: Is There a Difference in Regulation of Angiogenesis between Hormone-Receptor Positive and Negative Breast Cancer Cells?

Herr D, Sauer C, Holzheu I, Sauter R, Janni W, Wöckel A, Wulff C.

Geburtshilfe Frauenheilkd. 2019 Jun;79(6):626-634. doi: 10.1055/a-0887-7313. Epub 2019 Jun 14.


Large-scale lipidomics identifies associations between plasma sphingolipids and T2DM incidence.

Chew WS, Torta F, Ji S, Choi H, Begum H, Sim X, Khoo CM, Khoo EYH, Ong WY, Van Dam RM, Wenk MR, Tai ES, Herr DR.

JCI Insight. 2019 Jun 4;5. pii: 126925. doi: 10.1172/jci.insight.126925.


The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies.

Yu B, Zanetti KA, Temprosa M, Albanes D, Appel N, Barrera CB, Ben-Shlomo Y, Boerwinkle E, Casas JP, Clish C, Dale C, Dehghan A, Derkach A, Eliassen AH, Elliott P, Fahy E, Gieger C, Gunter MJ, Harada S, Harris T, Herr DR, Herrington D, Hirschhorn JN, Hoover E, Hsing AW, Johansson M, Kelly RS, Khoo CM, Kivimäki M, Kristal BS, Langenberg C, Lasky-Su J, Lawlor DA, Lotta LA, Mangino M, Le Marchand L, Mathé E, Matthews CE, Menni C, Mucci LA, Murphy R, Oresic M, Orwoll E, Ose J, Pereira AC, Playdon MC, Poston L, Price J, Qi Q, Rexrode K, Risch A, Sampson J, Seow WJ, Sesso HD, Shah SH, Shu XO, Smith GCS, Sovio U, Stevens VL, Stolzenberg-Solomon R, Takebayashi T, Tillin T, Travis R, Tzoulaki I, Ulrich CM, Vasan RS, Verma M, Wang Y, Wareham NJ, Wong A, Younes N, Zhao H, Zheng W, Moore SC.

Am J Epidemiol. 2019 Jun 1;188(6):991-1012. doi: 10.1093/aje/kwz028.


Mechanical Ventilation Management during Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome. An International Multicenter Prospective Cohort.

Schmidt M, Pham T, Arcadipane A, Agerstrand C, Ohshimo S, Pellegrino V, Vuylsteke A, Guervilly C, McGuinness S, Pierard S, Breeding J, Stewart C, Ching SSW, Camuso JM, Stephens RS, King B, Herr D, Schultz MJ, Neuville M, Zogheib E, Mira JP, Rozé H, Pierrot M, Tobin A, Hodgson C, Chevret S, Brodie D, Combes A.

Am J Respir Crit Care Med. 2019 Oct 15;200(8):1002-1012. doi: 10.1164/rccm.201806-1094OC.


Pilot study evaluating a non-titrating, weight-based anticoagulation scheme for patients on veno-venous extracorporeal membrane oxygenation.

Deatrick KB, Galvagno SM, Mazzeffi MA, Kaczoroswki DJ, Herr DL, Rector R, Hochberg E, Rabinowitz RP, Scalea TM, Menaker J.

Perfusion. 2020 Jan;35(1):13-18. doi: 10.1177/0267659119850024. Epub 2019 May 23.


Are Current Protein Recommendations for the Critically Ill Adequate for Patients on VV ECMO: Experience From a High-Volume Center.

Pelekhaty SL, Galvagno SM Jr, Lantry JH, Dolly KN, Herr DL, Kon ZN, Deatrick KB, Cornachione CR, Scalea TM, Menaker J.

JPEN J Parenter Enteral Nutr. 2019 May 15. doi: 10.1002/jpen.1602. [Epub ahead of print]


Female Adnexal Tumour of Probable Wolffian Origin (FATWO): Review of the Literature.

Hübner TB, Schwab M, Hartmann E, Mayr D, Thurner A, Bley T, Wöckel A, Herr D.

Geburtshilfe Frauenheilkd. 2019 Mar;79(3):281-285. doi: 10.1055/a-0746-8985. Epub 2019 Mar 12.


A randomized phase II study to determine the efficacy and tolerability of two doses of eribulin plus lapatinib in trastuzumab-pretreated patients with HER-2-positive metastatic breast cancer (E-VITA).

Bischoff J, Barinoff J, Mundhenke C, Bauerschlag DO, Costa SD, Herr D, Lübbe K, Marmé F, Maass N, von Minckwitz G, Grischke EM, Müller V, Schmidt M, Gerber B, Kümmel S, Schumacher C, Krabisch P, Seiler S, Thill M, Nekljudova V, Loibl S.

Anticancer Drugs. 2019 Apr;30(4):394-401. doi: 10.1097/CAD.0000000000000722.


Sphingosine 1-phosphate signaling induces SNAI2 expression to promote cell invasion in breast cancer cells.

Wang W, Hind T, Lam BWS, Herr DR.

FASEB J. 2019 Jun;33(6):7180-7191. doi: 10.1096/fj.201801635R. Epub 2019 Mar 7.


An analysis of the potential positive and negative livelihood impacts of coastal carbon offset projects.

Herr D, Blum J, Himes-Cornell A, Sutton-Grier A.

J Environ Manage. 2019 Apr 1;235:463-479. doi: 10.1016/j.jenvman.2019.01.067. Epub 2019 Jan 31.


Epidemiology of blood stream infection in adult extracorporeal membrane oxygenation patients: A cohort study.

Menaker J, Galvagno S, Rabinowitz R, Penchev V, Hollis A, Kon Z, Deatrick K, Amoroso A, Herr D, Mazzeffi M.

Heart Lung. 2019 May - Jun;48(3):236-239. doi: 10.1016/j.hrtlng.2019.01.004. Epub 2019 Jan 24.


Von Willebrand Factor-GP1bα Interactions in Venoarterial Extracorporeal Membrane Oxygenation Patients.

Mazzeffi M, Hasan S, Abuelkasem E, Meyer M, Deatrick K, Taylor B, Kon Z, Herr D, Tanaka K.

J Cardiothorac Vasc Anesth. 2019 Aug;33(8):2125-2132. doi: 10.1053/j.jvca.2018.11.031. Epub 2018 Nov 22.


Regional Cerebral Oximetry as an Indicator of Acute Brain Injury in Adults Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation-A Prospective Pilot Study.

Khan I, Rehan M, Parikh G, Zammit C, Badjatia N, Herr D, Kon Z, Hogue C, Mazzeffi M.

Front Neurol. 2018 Nov 23;9:993. doi: 10.3389/fneur.2018.00993. eCollection 2018.


Ambulation With Femoral Arterial Cannulation Can Be Safely Performed on Venoarterial Extracorporeal Membrane Oxygenation.

Pasrija C, Mackowick KM, Raithel M, Tran D, Boulos FM, Deatrick KB, Mazzeffi MA, Rector R, Pham SM, Griffith BP, Herr DL, Kon ZN.

Ann Thorac Surg. 2019 May;107(5):1389-1394. doi: 10.1016/j.athoracsur.2018.10.048. Epub 2018 Nov 30.


Large Dual-Lumen Extracorporeal Membrane Oxygenation Cannulas Are Associated with More Intracranial Hemorrhage.

Mazzeffi M, Kon Z, Menaker J, Johnson DM, Parise O, Gelsomino S, Lorusso R, Herr D.

ASAIO J. 2019 Sep/Oct;65(7):674-677. doi: 10.1097/MAT.0000000000000917.


Lysophosphatidic acid and its receptor LPA1 mediate carrageenan induced inflammatory pain in mice.

Srikanth M, Chew WS, Hind T, Lim SM, Hay NWJ, Lee JHM, Rivera R, Chun J, Ong WY, Herr DR.

Eur J Pharmacol. 2018 Dec 15;841:49-56. doi: 10.1016/j.ejphar.2018.10.005. Epub 2018 Oct 12.


Correction: Synthesis and evaluation of nuciferine and roemerine enantiomers as 5-HT2 and α1 receptor antagonists.

Heng HL, Chee CF, Chin SP, Ouyang Y, Wang H, Buckle MJC, Herr DR, Paterson IC, Doughty SW, Abd Rahman N, Chung LY.

Medchemcomm. 2018 Mar 7;9(3):593-594. doi: 10.1039/c8md90012d. eCollection 2018 Mar 1.


Metabolism of Docosahexaenoic Acid (DHA) Induces Pyroptosis in BV-2 Microglial Cells.

Srikanth M, Chandrasaharan K, Zhao X, Chayaburakul K, Ong WY, Herr DR.

Neuromolecular Med. 2018 Dec;20(4):504-514. doi: 10.1007/s12017-018-8511-0. Epub 2018 Sep 19.


In vitro functional evaluation of isolaureline, dicentrine and glaucine enantiomers at 5-HT2 and α1 receptors.

Heng HL, Chee CF, Thy CK, Tee JT, Chin SP, Herr DR, Buckle MJC, Paterson IC, Doughty SW, Abd Rahman N, Chung LY.

Chem Biol Drug Des. 2019 Feb;93(2):132-138. doi: 10.1111/cbdd.13390. Epub 2018 Oct 3.


Bleeding, Thrombosis, and Transfusion With Two Heparin Anticoagulation Protocols in Venoarterial ECMO Patients.

Mazzeffi MA, Tanaka K, Roberts A, Rector R, Menaker J, Kon Z, Deatrick KB, Kaczorowski D, Griffith B, Herr D.

J Cardiothorac Vasc Anesth. 2019 May;33(5):1216-1220. doi: 10.1053/j.jvca.2018.07.045. Epub 2018 Aug 3.


[Data sources on sick pay in the German health care system: An overview and recommendations for health services research].

Herr D.

Z Evid Fortbild Qual Gesundhwes. 2018 Sep;135-136:56-64. doi: 10.1016/j.zefq.2018.07.006. Epub 2018 Aug 17. Review. German.


Synthesis and evaluation of nuciferine and roemerine enantiomers as 5-HT2 and α1 receptor antagonists.

Heng HL, Chee CF, Chin SP, Ouyang Y, Wang H, Buckle MJC, Herr DR, Paterson IC, Doughty SW, Abd Rahman N, Chung LY.

Medchemcomm. 2018 Feb 26;9(3):576-582. doi: 10.1039/c7md00629b. eCollection 2018 Mar 1. Erratum in: Medchemcomm. 2018 Mar 7;9(3):593-594.


Interactive Molecular Graphics for Augmented Reality Using HoloLens.

Müller C, Krone M, Huber M, Biener V, Herr D, Koch S, Reina G, Weiskopf D, Ertl T.

J Integr Bioinform. 2018 Jun 13;15(2). pii: /j/jib.2018.15.issue-2/jib-2018-0005/jib-2018-0005.xml. doi: 10.1515/jib-2018-0005.


Role of the Prefrontal Cortex in Pain Processing.

Ong WY, Stohler CS, Herr DR.

Mol Neurobiol. 2019 Feb;56(2):1137-1166. doi: 10.1007/s12035-018-1130-9. Epub 2018 Jun 6. Review.


Nitrogen Balance During Venovenous Extracorporeal Membrane Oxygenation Support: Preliminary Results of a Prospective, Observational Study.

Pelekhaty S, Galvagno SM Jr, Hochberg E, Herr DL, Lantry JH, Kon ZN, Deatrick KB, Menaker J.

JPEN J Parenter Enteral Nutr. 2018 May 25. doi: 10.1002/jpen.1176. [Epub ahead of print]


Sphingolipidomics analysis of large clinical cohorts. Part 2: Potential impact and applications.

Chong JR, Xiang P, Wang W, Hind T, Chew WS, Ong WY, Lai MKP, Herr DR.

Biochem Biophys Res Commun. 2018 Oct 7;504(3):602-607. doi: 10.1016/j.bbrc.2018.04.075. Epub 2018 Apr 19. Review.


Sphingolipidomics analysis of large clinical cohorts. Part 1: Technical notes and practical considerations.

Chew WS, Seow WL, Chong JR, Lai MKP, Torta F, Wenk MR, Herr DR.

Biochem Biophys Res Commun. 2018 Oct 7;504(3):596-601. doi: 10.1016/j.bbrc.2018.04.076. Epub 2018 Apr 19. Review.


Development and characterization of a point-of care rate-based transcutaneous respiratory status monitor.

Ge X, Adangwa P, Lim JY, Kostov Y, Tolosa L, Pierson R, Herr D, Rao G.

Med Eng Phys. 2018 Jun;56:36-41. doi: 10.1016/j.medengphy.2018.03.009. Epub 2018 Apr 5.


Veno-Venous Extracorporeal Membrane Oxygenation for Respiratory Failure: How Long Is Too Long?

Menaker J, Rabinowitz RP, Tabatabai A, Tesoriero RB, Dolly K, Cornachione C, Stene E, Buchner J, Kufera J, Kon ZN, Deatrick KB, Herr DL, O'Connor JV, Scalea TM.

ASAIO J. 2019 Feb;65(2):192-196. doi: 10.1097/MAT.0000000000000791.


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