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Items: 1 to 50 of 106

1.

Identification of gene expression levels in primary melanoma associated with clinically meaningful characteristics.

Gorlov I, Orlow I, Ringelberg C, Hernando E, Ernstoff MS, Cheng C, Her S, Parker JS, Thompson CL, Gerstenblith MR, Berwick M, Amos C.

Melanoma Res. 2018 Jul 2. doi: 10.1097/CMR.0000000000000473. [Epub ahead of print]

PMID:
29975213
2.

Primary Melanoma Histologic Subtype: Impact on Survival and Response to Therapy.

Lattanzi M, Lee Y, Simpson D, Moran U, Darvishian F, Kim RH, Hernando E, Polsky D, Hanniford D, Shapiro R, Berman R, Pavlick AC, Wilson MA, Kirchhoff T, Weber JS, Zhong J, Osman I.

J Natl Cancer Inst. 2018 Jun 15. doi: 10.1093/jnci/djy086. [Epub ahead of print]

PMID:
29912415
3.

Differential phosphorylation and n-terminal configuration of capsid subunits in parvovirus assembly and viral trafficking.

Gil-Ranedo J, Hernando E, Valle N, Riolobos L, Maroto B, Almendral JM.

Virology. 2018 May;518:184-194. doi: 10.1016/j.virol.2018.02.018. Epub 2018 Mar 15.

PMID:
29524834
4.

Small molecule anionophores promote transmembrane anion permeation matching CFTR activity.

Hernando E, Capurro V, Cossu C, Fiore M, García-Valverde M, Soto-Cerrato V, Pérez-Tomás R, Moran O, Zegarra-Moran O, Quesada R.

Sci Rep. 2018 Feb 8;8(1):2608. doi: 10.1038/s41598-018-20708-3.

5.

Impact of Futsal and Swimming Participation on Bone Health in Young Athletes.

Seabra A, Fernandes RJ, Marques E, Moura M, Ubago-Guisado E, Hernando E, Gallardo L.

J Hum Kinet. 2017 Dec 28;60:85-91. doi: 10.1515/hukin-2017-0092. eCollection 2017 Dec.

6.

Lysyl oxidase-like 3 is required for melanoma cell survival by maintaining genomic stability.

Santamaría PG, Floristán A, Fontanals-Cirera B, Vázquez-Naharro A, Santos V, Morales S, Yuste L, Peinado H, García-Gómez A, Portillo F, Hernando E, Cano A.

Cell Death Differ. 2018 May;25(5):935-950. doi: 10.1038/s41418-017-0030-2. Epub 2017 Dec 11.

7.

miR-204-5p and miR-211-5p Contribute to BRAF Inhibitor Resistance in Melanoma.

Díaz-Martínez M, Benito-Jardón L, Alonso L, Koetz-Ploch L, Hernando E, Teixidó J.

Cancer Res. 2018 Feb 15;78(4):1017-1030. doi: 10.1158/0008-5472.CAN-17-1318. Epub 2017 Dec 11.

PMID:
29229605
8.

Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene.

Fontanals-Cirera B, Hasson D, Vardabasso C, Di Micco R, Agrawal P, Chowdhury A, Gantz M, de Pablos-Aragoneses A, Morgenstern A, Wu P, Filipescu D, Valle-Garcia D, Darvishian F, Roe JS, Davies MA, Vakoc CR, Hernando E, Bernstein E.

Mol Cell. 2017 Nov 16;68(4):731-744.e9. doi: 10.1016/j.molcel.2017.11.004.

9.

TYRP1 mRNA goes fishing for miRNAs in melanoma.

Soengas MS, Hernando E.

Nat Cell Biol. 2017 Oct 31;19(11):1311-1312. doi: 10.1038/ncb3637.

PMID:
29087386
10.

Neuromuscular responses and physiological patterns during a soccer simulation protocol. Artificial turf versus natural grass.

López-Fernández J, García-Unanue J, Sánchez-Sánchez J, León M, Hernando E, Gallardo L.

J Sports Med Phys Fitness. 2017 Sep 22. doi: 10.23736/S0022-4707.17.07768-4. [Epub ahead of print]

PMID:
28944649
11.

Inhibition of Human Enhancer of Zeste Homolog 2 with Tambjamine Analogs.

Kotev M, Manuel-Manresa P, Hernando E, Soto-Cerrato V, Orozco M, Quesada R, Pérez-Tomás R, Guallar V.

J Chem Inf Model. 2017 Aug 16. doi: 10.1021/acs.jcim.7b00178. [Epub ahead of print]

PMID:
28763207
12.

A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis.

Agrawal P, Fontanals-Cirera B, Sokolova E, Jacob S, Vaiana CA, Argibay D, Davalos V, McDermott M, Nayak S, Darvishian F, Castillo M, Ueberheide B, Osman I, Fenyö D, Mahal LK, Hernando E.

Cancer Cell. 2017 Jun 12;31(6):804-819.e7. doi: 10.1016/j.ccell.2017.05.007.

13.

Krüppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions.

Segura MF, Jubierre L, Li S, Soriano A, Koetz L, Gaziel-Sovran A, Masanas M, Kleffman K, Dankert JF, Walsh MJ, Hernando E.

Oncotarget. 2017 Apr 18;8(16):26298-26311. doi: 10.18632/oncotarget.15459.

14.

Novel Indole-based Tambjamine-Analogues Induce Apoptotic Lung Cancer Cell Death through p38 Mitogen-Activated Protein Kinase Activation.

Manuel-Manresa P, Korrodi-Gregório L, Hernando E, Villanueva A, Martínez-García D, Rodilla AM, Ramos R, Fardilha M, Moya J, Quesada R, Soto-Cerrato V, Pérez-Tomás R.

Mol Cancer Ther. 2017 Jul;16(7):1224-1235. doi: 10.1158/1535-7163.MCT-16-0752. Epub 2017 Apr 10.

15.

MicroRNA-125a promotes resistance to BRAF inhibitors through suppression of the intrinsic apoptotic pathway.

Koetz-Ploch L, Hanniford D, Dolgalev I, Sokolova E, Zhong J, Díaz-Martínez M, Bernstein E, Darvishian F, Flaherty KT, Chapman PB, Tawbi H, Hernando E.

Pigment Cell Melanoma Res. 2017 May;30(3):328-338. doi: 10.1111/pcmr.12578. Epub 2017 Apr 19.

16.

A TGFβ-miR-182-BRCA1 axis controls the mammary differentiation hierarchy.

Martinez-Ruiz H, Illa-Bochaca I, Omene C, Hanniford D, Liu Q, Hernando E, Barcellos-Hoff MH.

Sci Signal. 2016 Dec 6;9(457):ra118.

17.

Synthetic tambjamine analogues induce mitochondrial swelling and lysosomal dysfunction leading to autophagy blockade and necrotic cell death in lung cancer.

Rodilla AM, Korrodi-Gregório L, Hernando E, Manuel-Manresa P, Quesada R, Pérez-Tomás R, Soto-Cerrato V.

Biochem Pharmacol. 2017 Feb 15;126:23-33. doi: 10.1016/j.bcp.2016.11.022. Epub 2016 Nov 24.

PMID:
27890727
18.

Physical and Physiological Responses of Amateur Football Players on Third-Generation Artificial Turf Systems During Simulated Game Situations.

Sánchez-Sánchez J, García-Unanue J, Felipe JL, Jiménez-Reyes P, Viejo-Romero D, Gómez-López M, Hernando E, Burillo P, Gallardo L.

J Strength Cond Res. 2016 Nov;30(11):3165-3177.

PMID:
26982970
19.

BET and BRAF inhibitors act synergistically against BRAF-mutant melanoma.

Paoluzzi L, Hanniford D, Sokolova E, Osman I, Darvishian F, Wang J, Bradner JE, Hernando E.

Cancer Med. 2016 Jun;5(6):1183-93. doi: 10.1002/cam4.667. Epub 2016 May 11.

20.

QSAR analysis of substituent effects on tambjamine anion transporters.

Knight NJ, Hernando E, Haynes CJE, Busschaert N, Clarke HJ, Takimoto K, García-Valverde M, Frey JG, Quesada R, Gale PA.

Chem Sci. 2016 Feb 1;7(2):1600-1608. doi: 10.1039/c5sc03932k. Epub 2015 Dec 8.

21.

Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane That Triggers Differentiation and Cell Death in Cancer Stem Cells.

Soto-Cerrato V, Manuel-Manresa P, Hernando E, Calabuig-Fariñas S, Martínez-Romero A, Fernández-Dueñas V, Sahlholm K, Knöpfel T, García-Valverde M, Rodilla AM, Jantus-Lewintre E, Farràs R, Ciruela F, Pérez-Tomás R, Quesada R.

J Am Chem Soc. 2015 Dec 23;137(50):15892-8. doi: 10.1021/jacs.5b09970. Epub 2015 Dec 17.

PMID:
26632983
22.

SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150.

Barbáchano A, Fernández-Barral A, Pereira F, Segura MF, Ordóñez-Morán P, Carrillo-de Santa Pau E, González-Sancho JM, Hanniford D, Martínez N, Costales-Carrera A, Real FX, Pálmer HG, Rojas JM, Hernando E, Muñoz A.

Oncogene. 2016 Jun 9;35(23):2991-3003. doi: 10.1038/onc.2015.366. Epub 2015 Oct 12.

23.

Revisiting determinants of prognosis in cutaneous melanoma.

Weiss SA, Hanniford D, Hernando E, Osman I.

Cancer. 2015 Dec 1;121(23):4108-23. doi: 10.1002/cncr.29634. Epub 2015 Aug 26. Review.

24.

A miRNA-Based Signature Detected in Primary Melanoma Tissue Predicts Development of Brain Metastasis.

Hanniford D, Zhong J, Koetz L, Gaziel-Sovran A, Lackaye DJ, Shang S, Pavlick A, Shapiro R, Berman R, Darvishian F, Shao Y, Osman I, Hernando E.

Clin Cancer Res. 2015 Nov 1;21(21):4903-12. doi: 10.1158/1078-0432.CCR-14-2566. Epub 2015 Jun 18.

25.

The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid Assembly.

Gil-Ranedo J, Hernando E, Riolobos L, Domínguez C, Kann M, Almendral JM.

PLoS Pathog. 2015 Jun 11;11(6):e1004920. doi: 10.1371/journal.ppat.1004920. eCollection 2015 Jun.

26.

Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma.

Vardabasso C, Gaspar-Maia A, Hasson D, Pünzeler S, Valle-Garcia D, Straub T, Keilhauer EC, Strub T, Dong J, Panda T, Chung CY, Yao JL, Singh R, Segura MF, Fontanals-Cirera B, Verma A, Mann M, Hernando E, Hake SB, Bernstein E.

Mol Cell. 2015 Jul 2;59(1):75-88. doi: 10.1016/j.molcel.2015.05.009. Epub 2015 Jun 4.

27.

FBXW7 modulates cellular stress response and metastatic potential through ​HSF1 post-translational modification.

Kourtis N, Moubarak RS, Aranda-Orgilles B, Lui K, Aydin IT, Trimarchi T, Darvishian F, Salvaggio C, Zhong J, Bhatt K, Chen EI, Celebi JT, Lazaris C, Tsirigos A, Osman I, Hernando E, Aifantis I.

Nat Cell Biol. 2015 Mar;17(3):322-332. doi: 10.1038/ncb3121.

28.

Identification of metastasis-suppressive microRNAs in primary melanoma.

Hanniford D, Segura MF, Zhong J, Philips E, Jirau-Serrano X, Darvishian F, Berman RS, Shapiro RL, Pavlick AC, Brown B, Osman I, Hernando E.

J Natl Cancer Inst. 2015 Feb 12;107(3). pii: dju494. doi: 10.1093/jnci/dju494. Print 2015 Mar.

29.

Limited miR-17-92 overexpression drives hematologic malignancies.

Danielson LS, Reavie L, Coussens M, Davalos V, Castillo-Martin M, Guijarro MV, Coffre M, Cordon-Cardo C, Aifantis I, Ibrahim S, Liu C, Koralov SB, Hernando E.

Leuk Res. 2015 Mar;39(3):335-41. doi: 10.1016/j.leukres.2014.12.002. Epub 2014 Dec 10.

30.

Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes.

Di Micco R, Fontanals-Cirera B, Low V, Ntziachristos P, Yuen SK, Lovell CD, Dolgalev I, Yonekubo Y, Zhang G, Rusinova E, Gerona-Navarro G, Cañamero M, Ohlmeyer M, Aifantis I, Zhou MM, Tsirigos A, Hernando E.

Cell Rep. 2014 Oct 9;9(1):234-247. doi: 10.1016/j.celrep.2014.08.055. Epub 2014 Sep 26.

31.

Copper-catalyzed mild nitration of protected anilines.

Hernando E, Castillo RR, Rodríguez N, Gómez Arrayás R, Carretero JC.

Chemistry. 2014 Oct 20;20(43):13854-9. doi: 10.1002/chem.201404000. Epub 2014 Sep 11.

PMID:
25213167
32.

Serum-based miRNAs in the prediction and detection of recurrence in melanoma patients.

Fleming NH, Zhong J, da Silva IP, Vega-Saenz de Miera E, Brady B, Han SW, Hanniford D, Wang J, Shapiro RL, Hernando E, Osman I.

Cancer. 2015 Jan 1;121(1):51-9. doi: 10.1002/cncr.28981. Epub 2014 Aug 25.

33.

Anti-miR182 reduces ovarian cancer burden, invasion, and metastasis: an in vivo study in orthotopic xenografts of nude mice.

Xu X, Ayub B, Liu Z, Serna VA, Qiang W, Liu Y, Hernando E, Zabludoff S, Kurita T, Kong B, Wei JJ.

Mol Cancer Ther. 2014 Jul;13(7):1729-39. doi: 10.1158/1535-7163.MCT-13-0982. Epub 2014 May 13.

34.

[Laparoscopic repair of a giant intrathoracic hernia secondary to a diaphragmatic rupture].

Alday Muñoz E, Hernando E, Viamontes F, Planas Roca A.

Rev Esp Anestesiol Reanim. 2015 Feb;62(2):119. doi: 10.1016/j.redar.2014.02.012. Epub 2014 Apr 2. English, Spanish. No abstract available.

PMID:
24702969
35.

Transmembrane anion transport and cytotoxicity of synthetic tambjamine analogs.

Hernando E, Soto-Cerrato V, Cortés-Arroyo S, Pérez-Tomás R, Quesada R.

Org Biomol Chem. 2014 Mar 21;12(11):1771-8. doi: 10.1039/c3ob42341g.

PMID:
24500335
36.

Hedgehog pathway blockade inhibits melanoma cell growth in vitro and in vivo.

O'Reilly KE, de Miera EV, Segura MF, Friedman E, Poliseno L, Han SW, Zhong J, Zavadil J, Pavlick A, Hernando E, Osman I.

Pharmaceuticals (Basel). 2013 Nov 11;6(11):1429-50. doi: 10.3390/ph6111429.

37.

Clinicopathological characteristics at primary melanoma diagnosis as risk factors for brain metastasis.

Qian M, Ma MW, Fleming NH, Lackaye DJ, Hernando E, Osman I, Shao Y.

Melanoma Res. 2013 Dec;23(6):461-7. doi: 10.1097/CMR.0000000000000015.

38.

BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapy.

Segura MF, Fontanals-Cirera B, Gaziel-Sovran A, Guijarro MV, Hanniford D, Zhang G, González-Gomez P, Morante M, Jubierre L, Zhang W, Darvishian F, Ohlmeyer M, Osman I, Zhou MM, Hernando E.

Cancer Res. 2013 Oct 15;73(20):6264-76. doi: 10.1158/0008-5472.CAN-13-0122-T. Epub 2013 Aug 15.

39.

In vivo Modeling and Molecular Characterization: A Path Toward Targeted Therapy of Melanoma Brain Metastasis.

Gaziel-Sovran A, Osman I, Hernando E.

Front Oncol. 2013 May 31;3:127. doi: 10.3389/fonc.2013.00127. eCollection 2013.

40.

Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signaling.

Guijarro MV, Dahiya S, Danielson LS, Segura MF, Vales-Lara FM, Menendez S, Popiolek D, Mittal K, Wei JJ, Zavadil J, Cordon-Cardo C, Pandolfi PP, Hernando E.

Am J Pathol. 2013 Jun;182(6):2015-27. doi: 10.1016/j.ajpath.2013.02.035.

41.

Development and characterization of a clinically relevant mouse model of melanoma brain metastasis.

Morsi A, Gaziel-Sovran A, Cruz-Munoz W, Kerbel RS, Golfinos JG, Hernando E, Wadghiri YZ.

Pigment Cell Melanoma Res. 2013 Sep;26(5):743-5. doi: 10.1111/pcmr.12114. Epub 2013 Jun 4. No abstract available.

42.

FBH1 protects melanocytes from transformation and is deregulated in melanomas.

Jeong YT, Cermak L, Guijarro MV, Hernando E, Pagano M.

Cell Cycle. 2013 Apr 1;12(7):1128-32. doi: 10.4161/cc.24165. Epub 2013 Mar 6.

43.

Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis.

Danielson LS, Park DS, Rotllan N, Chamorro-Jorganes A, Guijarro MV, Fernandez-Hernando C, Fishman GI, Phoon CK, Hernando E.

FASEB J. 2013 Apr;27(4):1460-7. doi: 10.1096/fj.12-221994. Epub 2012 Dec 27.

44.

Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.

Pelczar P, Zibat A, van Dop WA, Heijmans J, Bleckmann A, Gruber W, Nitzki F, Uhmann A, Guijarro MV, Hernando E, Dittmann K, Wienands J, Dressel R, Wojnowski L, Binder C, Taguchi T, Beissbarth T, Hogendoorn PC, Antonescu CR, Rubin BP, Schulz-Schaeffer W, Aberger F, van den Brink GR, Hahn H.

Gastroenterology. 2013 Jan;144(1):134-144.e6. doi: 10.1053/j.gastro.2012.09.061. Epub 2012 Oct 3.

45.
46.

Catalytic asymmetric Mannich reaction of glycine Schiff bases with α-amido sulfones as precursors of aliphatic imines.

Hernando E, Gómez Arrayás R, Carretero JC.

Chem Commun (Camb). 2012 Oct 7;48(77):9622-4. doi: 10.1039/c2cc35160a.

PMID:
22911099
47.

Serum microRNAs as biomarkers for recurrence in melanoma.

Friedman EB, Shang S, de Miera EV, Fog JU, Teilum MW, Ma MW, Berman RS, Shapiro RL, Pavlick AC, Hernando E, Baker A, Shao Y, Osman I.

J Transl Med. 2012 Aug 2;10:155. doi: 10.1186/1479-5876-10-155.

48.

MicroRNA and cutaneous melanoma: from discovery to prognosis and therapy.

Segura MF, Greenwald HS, Hanniford D, Osman I, Hernando E.

Carcinogenesis. 2012 Oct;33(10):1823-32. doi: 10.1093/carcin/bgs205. Epub 2012 Jun 12. Review.

49.

Challenging the current paradigm of melanoma progression: brain metastasis as isolated first visceral site.

Ma MW, Qian M, Lackaye DJ, Berman RS, Shapiro RL, Pavlick AC, Golfinos JG, Parker EC, Darvishian F, Hernando E, Shao Y, Osman I.

Neuro Oncol. 2012 Jul;14(7):849-58. doi: 10.1093/neuonc/nos113. Epub 2012 May 3.

50.

Histology-specific microRNA alterations in melanoma.

Poliseno L, Haimovic A, Segura MF, Hanniford D, Christos PJ, Darvishian F, Wang J, Shapiro RL, Pavlick AC, Berman RS, Hernando E, Zavadil J, Osman I.

J Invest Dermatol. 2012 Jul;132(7):1860-8. doi: 10.1038/jid.2011.451. Epub 2012 May 3.

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