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Items: 24


Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis.

Shin JY, Hernandez-Ono A, Fedotova T, Östlund C, Lee MJ, Gibeley SB, Liang CC, Dauer WT, Ginsberg HN, Worman HJ.

J Clin Invest. 2019 Aug 13;130. pii: 129769. doi: 10.1172/JCI129769.


Normalization of Hepatic Homeostasis in the Npc1nmf164 Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor Vorinostat.

Munkacsi AB, Hammond N, Schneider RT, Senanayake DS, Higaki K, Lagutin K, Bloor SJ, Ory DS, Maue RA, Chen FW, Hernandez-Ono A, Dahlson N, Repa JJ, Ginsberg HN, Ioannou YA, Sturley SL.

J Biol Chem. 2017 Mar 17;292(11):4395-4410. doi: 10.1074/jbc.M116.770578. Epub 2016 Dec 28.


Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis.

Conlon DM, Thomas T, Fedotova T, Hernandez-Ono A, Di Paolo G, Chan RB, Ruggles K, Gibeley S, Liu J, Ginsberg HN.

J Clin Invest. 2016 Oct 3;126(10):3852-3867. doi: 10.1172/JCI86028. Epub 2016 Sep 6.


Type 1 Deiodinase Regulates ApoA-I Gene Expression and ApoA-I Synthesis Independent of Thyroid Hormone Signaling.

Liu J, Hernandez-Ono A, Graham MJ, Galton VA, Ginsberg HN.

Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1356-66. doi: 10.1161/ATVBAHA.116.307330. Epub 2016 May 5.


Complex effects of inhibiting hepatic apolipoprotein B100 synthesis in humans.

Reyes-Soffer G, Moon B, Hernandez-Ono A, Dionizovik-Dimanovski M, Jimenez J, Obunike J, Thomas T, Ngai C, Fontanez N, Donovan DS, Karmally W, Holleran S, Ramakrishnan R, Mittleman RS, Ginsberg HN.

Sci Transl Med. 2016 Jan 27;8(323):323ra12. doi: 10.1126/scitranslmed.aad2195. Erratum in: Sci Transl Med. 2016 Feb 10;8(325):325er3. Dionizovick-Dimanovski, Marija [corrected to Dionizovik-Dimanovski, Marija].


The combined hyperlipidemia caused by impaired Wnt-LRP6 signaling is reversed by Wnt3a rescue.

Go GW, Srivastava R, Hernandez-Ono A, Gang G, Smith SB, Booth CJ, Ginsberg HN, Mani A.

Cell Metab. 2014 Feb 4;19(2):209-20. doi: 10.1016/j.cmet.2013.11.023. Review.


Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying.

Ables GP, Yang KJ, Vogel S, Hernandez-Ono A, Yu S, Yuen JJ, Birtles S, Buckett LK, Turnbull AV, Goldberg IJ, Blaner WS, Huang LS, Ginsberg HN.

J Lipid Res. 2012 Nov;53(11):2364-79. doi: 10.1194/jlr.M029041. Epub 2012 Aug 21.


Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.

Ai D, Baez JM, Jiang H, Conlon DM, Hernandez-Ono A, Frank-Kamenetsky M, Milstein S, Fitzgerald K, Murphy AJ, Woo CW, Strong A, Ginsberg HN, Tabas I, Rader DJ, Tall AR.

J Clin Invest. 2012 May;122(5):1677-87. doi: 10.1172/JCI61248. Epub 2012 Apr 2.


Antisense reduction of 11β-hydroxysteroid dehydrogenase type 1 enhances energy expenditure and insulin sensitivity independent of food intake in C57BL/6J mice on a Western-type diet.

Li G, Hernandez-Ono A, Crooke RM, Graham MJ, Ginsberg HN.

Metabolism. 2012 Jun;61(6):823-35. doi: 10.1016/j.metabol.2011.11.008. Epub 2011 Dec 29.


Apolipoprotein B secretion is regulated by hepatic triglyceride, and not insulin, in a model of increased hepatic insulin signaling.

Moon BC, Hernandez-Ono A, Stiles B, Wu H, Ginsberg HN.

Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):236-46. doi: 10.1161/ATVBAHA.111.241356. Epub 2011 Dec 8. Erratum in: Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):e23.


Different fatty acids inhibit apoB100 secretion by different pathways: unique roles for ER stress, ceramide, and autophagy.

Caviglia JM, Gayet C, Ota T, Hernandez-Ono A, Conlon DM, Jiang H, Fisher EA, Ginsberg HN.

J Lipid Res. 2011 Sep;52(9):1636-51. doi: 10.1194/jlr.M016931. Epub 2011 Jun 30.


Effects of antisense-mediated inhibition of 11β-hydroxysteroid dehydrogenase type 1 on hepatic lipid metabolism.

Li G, Hernandez-Ono A, Crooke RM, Graham MJ, Ginsberg HN.

J Lipid Res. 2011 May;52(5):971-81. doi: 10.1194/jlr.M013748. Epub 2011 Mar 1.


Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis.

Biddinger SB, Hernandez-Ono A, Rask-Madsen C, Haas JT, Alemán JO, Suzuki R, Scapa EF, Agarwal C, Carey MC, Stephanopoulos G, Cohen DE, King GL, Ginsberg HN, Kahn CR.

Cell Metab. 2008 Feb;7(2):125-34. doi: 10.1016/j.cmet.2007.11.013.


Dietary 1,3-diacylglycerol protects against diet-induced obesity and insulin resistance.

Saito S, Hernandez-Ono A, Ginsberg HN.

Metabolism. 2007 Nov;56(11):1566-75.


Effects of triacylglycerol and diacylglycerol oils on blood clearance, tissue uptake, and hepatic apolipoprotein B secretion in mice.

Yasunaga K, Saito S, Zhang YL, Hernandez-Ono A, Ginsberg HN.

J Lipid Res. 2007 May;48(5):1108-21. Epub 2007 Feb 3.


Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis.

Zhang YL, Hernandez-Ono A, Siri P, Weisberg S, Conlon D, Graham MJ, Crooke RM, Huang LS, Ginsberg HN.

J Biol Chem. 2006 Dec 8;281(49):37603-15. Epub 2006 Sep 12.


Metabolic syndrome: focus on dyslipidemia.

Ginsberg HN, Zhang YL, Hernandez-Ono A.

Obesity (Silver Spring). 2006 Feb;14 Suppl 1:41S-49S. Review. No abstract available.


Regulation of plasma triglycerides in insulin resistance and diabetes.

Ginsberg HN, Zhang YL, Hernandez-Ono A.

Arch Med Res. 2005 May-Jun;36(3):232-40. Review.


Estrogen effect on heart rate variability in hypertensive postmenopausal women.

Rosa Brito-Zurita O, Posadas-Romero C, Hermosillo AG, Zamora-González J, Hernández-Ono A, Cardoso-Saldaña G, Torres-Tamayo M.

Maturitas. 2003 Jan 30;44(1):39-48.


Association of visceral fat with coronary risk factors in a population-based sample of postmenopausal women.

Hernández-Ono A, Monter-Carreola G, Zamora-González J, Cardoso-Saldaña G, Posadas-Sánchez R, Torres-Tamayo M, Posadas-Romero C.

Int J Obes Relat Metab Disord. 2002 Jan;26(1):33-9.


LDL size and susceptibility to oxidation in experimental nephrosis.

Posadas-Sánchez R, Posadas-Romero C, Zamora-González J, Hernández-Ono A, Baños-Marhaber G, Campos ON, Pedraza-Chaverrí J.

Mol Cell Biochem. 2001 Apr;220(1-2):61-8.


Differential effects of obesity with and without hyperinsulinemia on plasma lipoprotein(a) concentrations in men.

Posadas-Romero C, Hernández-Ono A, Zamora-González J, Cardoso-Saldaña G, Yamamoto-Kimura L, Brito-Zurita OR.

Metabolism. 2001 Feb;50(2):178-83.


No-scalpel vasectomy: review of the first 1,000 cases in a family medicine unit.

Arellano Lara S, Gonzalez Barrera JL, Hernandez Ono A, Moreno Alcazar O, Espinosa Perez J.

Arch Med Res. 1997 Winter;28(4):517-22.


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