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Items: 31


Corrigendum: The Polycomb proteins RING1B and EZH2 repress the tumoral pro-inflammatory function in metastasizing primary cutaneous squamous cell carcinoma.

Hernández-Ruiz E, Toll A, García-Diez I, Andrades E, Ferrandiz-Pulido C, Masferrer E, Yébenes M, Jaka A, Gimeno J, Gimeno R, García-Patos V, Pujol RM, Hernández-Muñoz I.

Carcinogenesis. 2019 Aug 22;40(8):1052. doi: 10.1093/carcin/bgz054. No abstract available.


Transcriptome and cytogenetic profiling analysis of matched in situ/invasive cutaneous squamous cell carcinomas from immunocompetent patients.

García-Díez I, Hernández-Muñoz I, Hernández-Ruiz E, Nonell L, Puigdecanet E, Bódalo-Torruella M, Andrades E, Pujol RM, Toll A.

Genes Chromosomes Cancer. 2019 Mar;58(3):164-174. doi: 10.1002/gcc.22712. Epub 2019 Jan 7.


A Myxoid Fibrotic Reaction Pattern is Associated with Metastatic Risk in Cutaneous Squamous Cell Carcinoma.

Hernández-Ruiz E, Hernández-Muñoz I, Masferrer E, Ferrándiz-Pulido C, Andrades E, Gimeno J, Duran X, García-Patos V, Pujol RM, Toll A.

Acta Derm Venereol. 2019 Jan 1;99(1):89-94. doi: 10.2340/00015555-3025.


PD-L1 Expression is Increased in Metastasizing Squamous Cell Carcinomas and Their Metastases.

García-Díez I, Hernández-Ruiz E, Andrades E, Gimeno J, Ferrándiz-Pulido C, Yébenes M, García-Patos V, Pujol RM, Hernández-Muñoz I, Toll A.

Am J Dermatopathol. 2018 Sep;40(9):647-654. doi: 10.1097/DAD.0000000000001164. Erratum in: Am J Dermatopathol. 2019 Jul;41(7):537.


The Polycomb proteins RING1B and EZH2 repress the tumoral pro-inflammatory function in metastasizing primary cutaneous squamous cell carcinoma.

Hernández-Ruiz E, Toll A, García-Diez I, Andrades E, Ferrandiz-Pulido C, Masferrer E, Yébenes M, Jaka A, Gimeno J, Gimeno R, García-Patos V, Pujol RM, Hernández-Muñoz I.

Carcinogenesis. 2018 Mar 8;39(3):503-513. doi: 10.1093/carcin/bgy016.


Histopathologic and Immunohistochemical Correlates of Confocal Descriptors in Pigmented Facial Macules on Photodamaged Skin.

Gómez-Martín I, Moreno S, Andrades-López E, Hernández-Muñoz I, Gallardo F, Barranco C, Pujol RM, Segura S.

JAMA Dermatol. 2017 Aug 1;153(8):771-780. doi: 10.1001/jamadermatol.2017.1323.


MiR-204 silencing in intraepithelial to invasive cutaneous squamous cell carcinoma progression.

Toll A, Salgado R, Espinet B, Díaz-Lagares A, Hernández-Ruiz E, Andrades E, Sandoval J, Esteller M, Pujol RM, Hernández-Muñoz I.

Mol Cancer. 2016 Jul 25;15(1):53. doi: 10.1186/s12943-016-0537-z.


RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein.

Hernandez-Muñoz I, Figuerola E, Sanchez-Molina S, Rodriguez E, Fernández-Mariño AI, Pardo-Pastor C, Bahamonde MI, Fernández-Fernández JM, García-Domínguez DJ, Hontecillas-Prieto L, Lavarino C, Carcaboso AM, de Torres C, Tirado OM, de Alava E, Mora J.

Oncotarget. 2016 Jul 19;7(29):46283-46300. doi: 10.18632/oncotarget.10092.


Epithelial-to-mesenchymal transition in penile squamous cell carcinoma.

Masferrer E, Ferrándiz-Pulido C, Masferrer-Niubò M, Rodríguez-Rodríguez A, Gil I, Pont A, Servitje O, García de Herreros A, Lloveras B, García-Patos V, Pujol RM, Toll A, Hernández-Muñoz I.

J Urol. 2015 Feb;193(2):699-705. doi: 10.1016/j.juro.2014.07.083. Epub 2014 Jul 22.


The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells.

Bosch A, Panoutsopoulou K, Corominas JM, Gimeno R, Moreno-Bueno G, Martín-Caballero J, Morales S, Lobato T, Martínez-Romero C, Farias EF, Mayol X, Cano A, Hernández-Muñoz I.

Oncotarget. 2014 Apr 30;5(8):2065-76.


Epithelial to mesenchymal transition markers are associated with an increased metastatic risk in primary cutaneous squamous cell carcinomas but are attenuated in lymph node metastases.

Toll A, Masferrer E, Hernández-Ruiz ME, Ferrandiz-Pulido C, Yébenes M, Jaka A, Tuneu A, Jucglà A, Gimeno J, Baró T, Casado B, Gandarillas A, Costa I, Mojal S, Peña R, de Herreros AG, García-Patos V, Pujol RM, Hernández-Muñoz I.

J Dermatol Sci. 2013 Nov;72(2):93-102. doi: 10.1016/j.jdermsci.2013.07.001. Epub 2013 Jul 15.


Pancreatic ductal adenocarcinoma and transcription factors: role of c-Myc.

Skoudy A, Hernández-Muñoz I, Navarro P.

J Gastrointest Cancer. 2011 Jun;42(2):76-84. doi: 10.1007/s12029-011-9258-0. Review.


Chromatin regulators: weaving epigenetic nets.

Hernández-Muñoz I.

Biomol Concepts. 2010 Oct 1;1(3-4):225-38. doi: 10.1515/bmc.2010.023.


The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma.

Martínez-Romero C, Rooman I, Skoudy A, Guerra C, Molero X, González A, Iglesias M, Lobato T, Bosch A, Barbacid M, Real FX, Hernández-Muñoz I.

J Pathol. 2009 Oct;219(2):205-13. doi: 10.1002/path.2585.


Pancreatic ductal adenocarcinoma: cellular origin, signaling pathways and stroma contribution.

Hernández-Muñoz I, Skoudy A, Real FX, Navarro P.

Pancreatology. 2008;8(4-5):462-9. doi: 10.1159/000151537. Epub 2008 Aug 25. Review.


Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor.

Herranz N, Pasini D, Díaz VM, Francí C, Gutierrez A, Dave N, Escrivà M, Hernandez-Muñoz I, Di Croce L, Helin K, García de Herreros A, Peiró S.

Mol Cell Biol. 2008 Aug;28(15):4772-81. doi: 10.1128/MCB.00323-08. Epub 2008 Jun 2.


Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome.

Nusinow DA, Hernández-Muñoz I, Fazzio TG, Shah GM, Kraus WL, Panning B.

J Biol Chem. 2007 Apr 27;282(17):12851-9. Epub 2007 Feb 23.


Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1.

Hernández-Muñoz I, Taghavi P, Kuijl C, Neefjes J, van Lohuizen M.

Mol Cell Biol. 2005 Dec;25(24):11047-58.


Emerging roles of Polycomb silencing in X-inactivation and stem cell maintenance.

Muyrers-Chen I, Hernández-Muñoz I, Lund AH, Valk-Lingbeek ME, van der Stoop P, Boutsma E, Tolhuis B, Bruggeman SW, Taghavi P, Verhoeven E, Hulsman D, Noback S, Tanger E, Theunissen H, van Lohuizen M.

Cold Spring Harb Symp Quant Biol. 2004;69:319-26. Review. No abstract available.


Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase.

Hernández-Muñoz I, Lund AH, van der Stoop P, Boutsma E, Muijrers I, Verhoeven E, Nusinow DA, Panning B, Marahrens Y, van Lohuizen M.

Proc Natl Acad Sci U S A. 2005 May 24;102(21):7635-40. Epub 2005 May 16.


NF1 modulates the effects of Ras oncogenes: evidence of other NF1 function besides its GAP activity.

Corral T, Jiménez M, Hernández-Muñoz I, Pérez de Castro I, Pellicer A.

J Cell Physiol. 2003 Nov;197(2):214-24.


rgr oncogene: activation by elimination of translational controls and mislocalization.

Hernández-Muñoz I, Benet M, Calero M, Jiménez M, Díaz R, Pellicer A.

Cancer Res. 2003 Jul 15;63(14):4188-95.


Reactive oxygen species mediate the down-regulation of mitochondrial transcripts and proteins by tumour necrosis factor-alpha in L929 cells.

Sánchez-Alcázar JA, Schneider E, Hernández-Muñoz I, Ruiz-Cabello J, Siles-Rivas E, de la Torre P, Bornstein B, Brea G, Arenas J, Garesse R, Solís-Herruzo JA, Knox AJ, Navas P.

Biochem J. 2003 Mar 1;370(Pt 2):609-19.


Human rgr: transforming activity and alteration in T-cell malignancies.

Leonardi P, Kassin E, Hernandez-Muñoz I, Diaz R, Inghirami G, Pellicer A.

Oncogene. 2002 Aug 1;21(33):5108-16.


The Rgr oncogene (homologous to RalGDS) induces transformation and gene expression by activating Ras, Ral and Rho mediated pathways.

Hernandez-Muñoz I, Malumbres M, Leonardi P, Pellicer A.

Oncogene. 2000 May 25;19(23):2745-57.


Tumor necrosis factor-alpha increases the steady-state reduction of cytochrome b of the mitochondrial respiratory chain in metabolically inhibited L929 cells.

Sánchez-Alcázar JA, Schneider E, Martínez MA, Carmona P, Hernández-Muñoz I, Siles E, De La Torre P, Ruiz-Cabello J, García I, Solis-Herruzo JA.

J Biol Chem. 2000 May 5;275(18):13353-61.


Tumor necrosis factor-alpha increases ATP content in metabolically inhibited L929 cells preceding cell death.

Sánchez-Alcázar JA, Ruíz-Cabello J, Hernández-Muñoz I, Pobre PS, de la Torre P, Siles-Rivas E, García I, Kaplan O, Muñoz-Yagüe MT, Solís-Herruzo JA.

J Biol Chem. 1997 Nov 28;272(48):30167-77.


Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G protein.

Hernández-Muñoz I, de la Torre P, Sánchez-Alcázar JA, García I, Santiago E, Muñoz-Yagüe MT, Solís-Herruzo JA.

Gastroenterology. 1997 Aug;113(2):625-40.


Toxic oil stimulates collagen synthesis acting at a pretranslational level in cultured fat-storing cells.

Hernández-Muñoz I, de la Torre MP, Pedraza MA, Sánchez-Alcázar JA, Muñoz-Yagüe MT, Solis-Herruzo JA.

Gastroenterology. 1994 Mar;106(3):691-701.


Reversal of carbon tetrachloride induced changes in microviscosity and lipid composition of liver plasma membrane by colchicine in rats.

Solis-Herruzo JA, De Gando M, Ferrer MP, Hernandez Muñoz I, Fernandez-Boya B, De la Torre MP, Muñoz-Yague MT.

Gut. 1993 Oct;34(10):1438-42.


Diminished cytochrome b content and toxic oxygen metabolite production in circulating neutrophils from patients with Crohn's disease.

Solis-Herruzo JA, Fernandez B, Vilalta-Castell E, Muñoz-Yagüe MT, Hernandez-Muñoz I, de la Torre-Merino MP, Balsinde J.

Dig Dis Sci. 1993 Sep;38(9):1631-7.


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