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Items: 24


Translational methods to detect asymmetries in temporal and spatial walking metrics in parkinsonian mouse models and human subjects with Parkinson's disease.

Broom L, Worley A, Gao F, Hernandez LD, Ashton CE, Shih LC, VanderHorst VG.

Sci Rep. 2019 Feb 21;9(1):2437. doi: 10.1038/s41598-019-38623-6.


Psychometric validation of an empowerment scale for Spanish-speaking patients with rheumatoid arthritis.

Contreras-Yáñez I, Ruiz-Medrano E, Hernández LDCR, Pascual-Ramos V.

Arthritis Res Ther. 2018 Oct 30;20(1):244. doi: 10.1186/s13075-018-1741-6.


Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor-binding determinants.

Gupta P, Zhang Z, Sugiman-Marangos SN, Tam J, Raman S, Julien JP, Kroh HK, Lacy DB, Murgolo N, Bekkari K, Therien AG, Hernandez LD, Melnyk RA.

J Biol Chem. 2017 Oct 20;292(42):17290-17301. doi: 10.1074/jbc.M117.806687. Epub 2017 Aug 23.


Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab.

Hernandez LD, Kroh HK, Hsieh E, Yang X, Beaumont M, Sheth PR, DiNunzio E, Rutherford SA, Ohi MD, Ermakov G, Xiao L, Secore S, Karczewski J, Racine F, Mayhood T, Fischer P, Sher X, Gupta P, Lacy DB, Therien AG.

J Mol Biol. 2017 Apr 7;429(7):1030-1044. doi: 10.1016/j.jmb.2017.02.010. Epub 2017 Feb 21.


Disease Progression and Resolution in Rodent Models of Clostridium difficile Infection and Impact of Antitoxin Antibodies and Vancomycin.

Warn P, Thommes P, Sattar A, Corbett D, Flattery A, Zhang Z, Black T, Hernandez LD, Therien AG.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6471-6482. doi: 10.1128/AAC.00974-16. Print 2016 Nov.


Correction for Zhang et al., Toxin-mediated paracellular transport of antitoxin antibodies facilitates protection against Clostridium difficile infection.

Zhang Z, Chen X, Hernandez LD, Lipari P, Flattery A, Chen SC, Kramer S, Polishook JD, Racine F, Cape H, Kelly CP, Therien AG.

Infect Immun. 2015 Dec;83(12):4899. doi: 10.1128/IAI.01214-15. No abstract available.


Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy.

Blair LJ, Frauen HD, Zhang B, Nordhues BA, Bijan S, Lin YC, Zamudio F, Hernandez LD, Sabbagh JJ, Selenica ML, Dickey CA.

Acta Neuropathol Commun. 2015 Jan 31;3:8. doi: 10.1186/s40478-015-0186-2.


Mechanisms of protection against Clostridium difficile infection by the monoclonal antitoxin antibodies actoxumab and bezlotoxumab.

Yang Z, Ramsey J, Hamza T, Zhang Y, Li S, Yfantis HG, Lee D, Hernandez LD, Seghezzi W, Furneisen JM, Davis NM, Therien AG, Feng H.

Infect Immun. 2015 Feb;83(2):822-31. doi: 10.1128/IAI.02897-14. Epub 2014 Dec 8.


Broad coverage of genetically diverse strains of Clostridium difficile by actoxumab and bezlotoxumab predicted by in vitro neutralization and epitope modeling.

Hernandez LD, Racine F, Xiao L, DiNunzio E, Hairston N, Sheth PR, Murgolo NJ, Therien AG.

Antimicrob Agents Chemother. 2015 Feb;59(2):1052-60. doi: 10.1128/AAC.04433-14. Epub 2014 Dec 1.


Toxin-mediated paracellular transport of antitoxin antibodies facilitates protection against Clostridium difficile infection.

Zhang Z, Chen X, Hernandez LD, Lipari P, Flattery A, Chen SC, Kramer S, Polishook JD, Racine F, Cape H, Kelly CP, Therien AG.

Infect Immun. 2015 Jan;83(1):405-16. doi: 10.1128/IAI.02550-14. Epub 2014 Nov 10. Erratum in: Infect Immun. 2015 Dec;83(12):4899.


Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography.

Orth P, Xiao L, Hernandez LD, Reichert P, Sheth PR, Beaumont M, Yang X, Murgolo N, Ermakov G, DiNunzio E, Racine F, Karczewski J, Secore S, Ingram RN, Mayhood T, Strickland C, Therien AG.

J Biol Chem. 2014 Jun 27;289(26):18008-21. doi: 10.1074/jbc.M114.560748. Epub 2014 May 12.


CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength.

Harries LW, Pilling LC, Hernandez LD, Bradley-Smith R, Henley W, Singleton AB, Guralnik JM, Bandinelli S, Ferrucci L, Melzer D.

Aging Cell. 2012 Apr;11(2):262-8. doi: 10.1111/j.1474-9726.2011.00782.x. Epub 2012 Jan 13.


Salmonella modulates vesicular traffic by altering phosphoinositide metabolism.

Hernandez LD, Hueffer K, Wenk MR, Galán JE.

Science. 2004 Jun 18;304(5678):1805-7.


A Salmonella protein causes macrophage cell death by inducing autophagy.

Hernandez LD, Pypaert M, Flavell RA, Galán JE.

J Cell Biol. 2003 Dec 8;163(5):1123-31.


Receptor-activated binding of viral fusion proteins to target membranes.

Earp LJ, Hernandez LD, Delos SE, White JM.

Methods Enzymol. 2003;372:428-40. No abstract available.


IRAK-M is a negative regulator of Toll-like receptor signaling.

Kobayashi K, Hernandez LD, Galán JE, Janeway CA Jr, Medzhitov R, Flavell RA.

Cell. 2002 Jul 26;110(2):191-202.


RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems.

Kobayashi K, Inohara N, Hernandez LD, Galán JE, Núñez G, Janeway CA, Medzhitov R, Flavell RA.

Nature. 2002 Mar 14;416(6877):194-9.


Activation of a retroviral membrane fusion protein: soluble receptor-induced liposome binding of the ALSV envelope glycoprotein.

Hernandez LD, Peters RJ, Delos SE, Young JA, Agard DA, White JM.

J Cell Biol. 1997 Dec 15;139(6):1455-64.


Synthesis of small heat-shock proteins is part of the developmental program of late seed maturation.

Wehmeyer N, Hernandez LD, Finkelstein RR, Vierling E.

Plant Physiol. 1996 Oct;112(2):747-57.


Virus-cell and cell-cell fusion.

Hernandez LD, Hoffman LR, Wolfsberg TG, White JM.

Annu Rev Cell Dev Biol. 1996;12:627-61. Review.


Receptor-induced conformational changes in the subgroup A avian leukosis and sarcoma virus envelope glycoprotein.

Gilbert JM, Hernandez LD, Balliet JW, Bates P, White JM.

J Virol. 1995 Dec;69(12):7410-5.


Generation of a water-soluble oligomeric ectodomain of the Rous sarcoma virus envelope glycoprotein.

Gilbert JM, Hernandez LD, Chernov-Rogan T, White JM.

J Virol. 1993 Nov;67(11):6889-92.


Expression of Low Molecular Weight Heat-Shock Proteins under Field Conditions.

Hernandez LD, Vierling E.

Plant Physiol. 1993 Apr;101(4):1209-1216.

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