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Items: 43


Role for the splicing factor TCERG1 in Cajal body integrity and snRNP assembly.

Moreno-Castro C, Prieto-Sánchez S, Sánchez-Hernández N, Hernández-Munain C, Suñé C.

J Cell Sci. 2019 Nov 14;132(22). pii: jcs232728. doi: 10.1242/jcs.232728.


Development and characterization of an improved formulation of cholesteryl oleate-loaded cationic solid-lipid nanoparticles as an efficient non-viral gene delivery system.

Limeres MJ, Suñé-Pou M, Prieto-Sánchez S, Moreno-Castro C, Nusblat AD, Hernández-Munain C, Castro GR, Suñé C, Suñé-Negre JM, Cuestas ML.

Colloids Surf B Biointerfaces. 2019 Dec 1;184:110533. doi: 10.1016/j.colsurfb.2019.110533. Epub 2019 Sep 29.


Improved synthesis and characterization of cholesteryl oleate-loaded cationic solid lipid nanoparticles with high transfection efficiency for gene therapy applications.

Suñé-Pou M, Limeres MJ, Nofrerias I, Nardi-Ricart A, Prieto-Sánchez S, El-Yousfi Y, Pérez-Lozano P, García-Montoya E, Miñarro-Carmona M, Ticó JR, Hernández-Munain C, Suñé C, Suñé-Negre JM.

Colloids Surf B Biointerfaces. 2019 Aug 1;180:159-167. doi: 10.1016/j.colsurfb.2019.04.037. Epub 2019 Apr 17.


Notch Signaling Controls Transcription via the Recruitment of RUNX1 and MYB to Enhancers during T Cell Development.

Rodríguez-Caparrós A, García V, Casal Á, López-Ros J, García-Mariscal A, Tani-Ichi S, Ikuta K, Hernández-Munain C.

J Immunol. 2019 Apr 15;202(8):2460-2472. doi: 10.4049/jimmunol.1801650. Epub 2019 Mar 15.


Cholesteryl oleate-loaded cationic solid lipid nanoparticles as carriers for efficient gene-silencing therapy.

Suñé-Pou M, Prieto-Sánchez S, El Yousfi Y, Boyero-Corral S, Nardi-Ricart A, Nofrerias-Roig I, Pérez-Lozano P, García-Montoya E, Miñarro-Carmona M, Ticó JR, Suñé-Negre JM, Hernández-Munain C, Suñé C.

Int J Nanomedicine. 2018 May 30;13:3223-3233. doi: 10.2147/IJN.S158884. eCollection 2018.


Targeting proteins to RNA transcription and processing sites within the nucleus.

Sánchez-Hernández N, Prieto-Sánchez S, Moreno-Castro C, Muñoz-Cobo JP, El Yousfi Y, Boyero-Corral S, Suñé-Pou M, Hernández-Munain C, Suñé C.

Int J Biochem Cell Biol. 2017 Oct;91(Pt B):194-202. doi: 10.1016/j.biocel.2017.06.001. Epub 2017 Jun 6. Review.


Targeting Splicing in the Treatment of Human Disease.

Suñé-Pou M, Prieto-Sánchez S, Boyero-Corral S, Moreno-Castro C, El Yousfi Y, Suñé-Negre JM, Hernández-Munain C, Suñé C.

Genes (Basel). 2017 Feb 24;8(3). pii: E87. doi: 10.3390/genes8030087. Review.


Transcriptional Elongation Regulator 1 Affects Transcription and Splicing of Genes Associated with Cellular Morphology and Cytoskeleton Dynamics and Is Required for Neurite Outgrowth in Neuroblastoma Cells and Primary Neuronal Cultures.

Muñoz-Cobo JP, Sánchez-Hernández N, Gutiérrez S, El Yousfi Y, Montes M, Gallego C, Hernández-Munain C, Suñé C.

Mol Neurobiol. 2017 Dec;54(10):7808-7823. doi: 10.1007/s12035-016-0284-6. Epub 2016 Nov 14.


Improved formulation of cationic solid lipid nanoparticles displays cellular uptake and biological activity of nucleic acids.

Fàbregas A, Prieto-Sánchez S, Suñé-Pou M, Boyero-Corral S, Ticó JR, García-Montoya E, Pérez-Lozano P, Miñarro M, Suñé-Negre JM, Hernández-Munain C, Suñé C.

Int J Pharm. 2017 Jan 10;516(1-2):39-44. doi: 10.1016/j.ijpharm.2016.11.026. Epub 2016 Nov 10.


The in vivo dynamics of TCERG1, a factor that couples transcriptional elongation with splicing.

Sánchez-Hernández N, Boireau S, Schmidt U, Muñoz-Cobo JP, Hernández-Munain C, Bertrand E, Suñé C.

RNA. 2016 Apr;22(4):571-82. doi: 10.1261/rna.052795.115. Epub 2016 Feb 12.


Prp40 and early events in splice site definition.

Becerra S, Andrés-León E, Prieto-Sánchez S, Hernández-Munain C, Suñé C.

Wiley Interdiscip Rev RNA. 2016 Jan-Feb;7(1):17-32. doi: 10.1002/wrna.1312. Epub 2015 Oct 23. Review.


Functional Consequences for Apoptosis by Transcription Elongation Regulator 1 (TCERG1)-Mediated Bcl-x and Fas/CD95 Alternative Splicing.

Montes M, Coiras M, Becerra S, Moreno-Castro C, Mateos E, Majuelos J, Oliver FJ, Hernández-Munain C, Alcamí J, Suñé C.

PLoS One. 2015 Oct 13;10(10):e0139812. doi: 10.1371/journal.pone.0139812. eCollection 2015.


Recent insights into the transcriptional control of the Tcra/Tcrd locus by distant enhancers during the development of T-lymphocytes.

Hernández-Munain C.

Transcription. 2015;6(4):65-73. doi: 10.1080/21541264.2015.1078429. Review.


T-cell receptor α enhancer is inactivated in αβ T lymphocytes.

del Blanco B, Angulo Ú, Krangel MS, Hernández-Munain C.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1744-53. doi: 10.1073/pnas.1406551112. Epub 2015 Mar 23.


Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF65 and modulates alternative pre-mRNA splicing in vivo.

Becerra S, Montes M, Hernández-Munain C, Suñé C.

RNA. 2015 Mar;21(3):438-57. doi: 10.1261/rna.047258.114. Epub 2015 Jan 20.


A new optimized formulation of cationic solid lipid nanoparticles intended for gene delivery: development, characterization and DNA binding efficiency of TCERG1 expression plasmid.

Fàbregas A, Sánchez-Hernández N, Ticó JR, García-Montoya E, Pérez-Lozano P, Suñé-Negre JM, Hernández-Munain C, Suñé C, Miñarro M.

Int J Pharm. 2014 Oct 1;473(1-2):270-9. doi: 10.1016/j.ijpharm.2014.06.022. Epub 2014 Jul 3.


Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication.

Coiras M, Montes M, Montanuy I, López-Huertas MR, Mateos E, Le Sommer C, Garcia-Blanco MA, Hernández-Munain C, Alcamí J, Suñé C.

Retrovirology. 2013 Oct 28;10:124. doi: 10.1186/1742-4690-10-124.


The FF4 and FF5 domains of transcription elongation regulator 1 (TCERG1) target proteins to the periphery of speckles.

Sánchez-Hernández N, Ruiz L, Sánchez-Álvarez M, Montes M, Macias MJ, Hernández-Munain C, Suñé C.

J Biol Chem. 2012 May 18;287(21):17789-800. doi: 10.1074/jbc.M111.304782. Epub 2012 Mar 27.


Tcra enhancer activation by inducible transcription factors downstream of pre-TCR signaling.

del Blanco B, García-Mariscal A, Wiest DL, Hernández-Munain C.

J Immunol. 2012 Apr 1;188(7):3278-93. doi: 10.4049/jimmunol.1100271. Epub 2012 Feb 22.


TCERG1 regulates alternative splicing of the Bcl-x gene by modulating the rate of RNA polymerase II transcription.

Montes M, Cloutier A, Sánchez-Hernández N, Michelle L, Lemieux B, Blanchette M, Hernández-Munain C, Chabot B, Suñé C.

Mol Cell Biol. 2012 Feb;32(4):751-62. doi: 10.1128/MCB.06255-11. Epub 2011 Dec 12.


Control of V(D)J Recombination through Transcriptional Elongation and Changes in Locus Chromatin Structure and Nuclear Organization.

Del Blanco B, García V, García-Mariscal A, Hernández-Munain C.

Genet Res Int. 2011;2011:970968. doi: 10.4061/2011/970968. Epub 2011 Sep 29.


Differential effects of sumoylation on transcription and alternative splicing by transcription elongation regulator 1 (TCERG1).

Sánchez-Alvarez M, Montes M, Sánchez-Hernández N, Hernández-Munain C, Suñé C.

J Biol Chem. 2010 May 14;285(20):15220-33. doi: 10.1074/jbc.M109.063750. Epub 2010 Mar 9.


Flexible stereospecific interactions and composition within nucleoprotein complexes assembled on the TCR alpha gene enhancer.

Del Blanco B, Roberts JL, Zamarreño N, Balmelle-Devaux N, Hernández-Munain C.

J Immunol. 2009 Aug 1;183(3):1871-83. doi: 10.4049/jimmunol.0803351. Epub 2009 Jul 13.


Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9.

Montanuy I, Torremocha R, Hernández-Munain C, Suñé C.

J Biol Chem. 2008 Mar 21;283(12):7368-78. doi: 10.1074/jbc.M706243200. Epub 2008 Jan 24.


A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells.

Bouchon A, Hernández-Munain C, Cella M, Colonna M.

J Exp Med. 2001 Oct 15;194(8):1111-22.


Accessibility control of T cell receptor gene rearrangement in developing thymocytes. The TCR alpha/delta locus.

Krangel MS, McMurry MT, Hernandez-Munain C, Zhong XP, Carabana J.

Immunol Res. 2000;22(2-3):127-35. Review.


Regulation of chromatin accessibility for V(D)J recombination.

Hernandez-Munain C, McMurry MT, Krangel MS.

Cold Spring Harb Symp Quant Biol. 1999;64:183-9. Review. No abstract available.


Chemokine production by G protein-coupled receptor activation in a human mast cell line: roles of extracellular signal-regulated kinase and NFAT.

Ali H, Ahamed J, Hernandez-Munain C, Baron JL, Krangel MS, Patel DD.

J Immunol. 2000 Dec 15;165(12):7215-23.


A developmental switch from TCR delta enhancer to TCR alpha enhancer function during thymocyte maturation.

Hernández-Munain C, Sleckman BP, Krangel MS.

Immunity. 1999 Jun;10(6):723-33.


Developmental regulation of V(D)J recombination at the TCR alpha/delta locus.

Krangel MS, Hernandez-Munain C, Lauzurica P, McMurry M, Roberts JL, Zhong XP.

Immunol Rev. 1998 Oct;165:131-47. Review.


Enhancer control of local accessibility to V(D)J recombinase.

McMurry MT, Hernandez-Munain C, Lauzurica P, Krangel MS.

Mol Cell Biol. 1997 Aug;17(8):4553-61.


Regulation of T cell receptor delta gene rearrangement by c-Myb.

Hernández-Munain C, Lauzurica P, Krangel MS.

J Exp Med. 1996 Jan 1;183(1):289-93.


Transcriptional regulation of the human T cell receptor delta gene.

Redondo JM, Hernandez-Munain C, Krangel MS.

Immunobiology. 1995 Jul;193(2-4):288-92. Review.


c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor delta enhancer.

Hernandez-Munain C, Krangel MS.

Mol Cell Biol. 1995 Jun;15(6):3090-9. Erratum in: Mol Cell Biol 1995 Aug;15(8):4659.


Trypanosoma cruzi: identification of a membrane cysteine proteinase linked through a GPI anchor.

Fresno M, Hernández-Munaín C, de-Diego J, Rivas L, Scharfstein J, Bonay P.

Braz J Med Biol Res. 1994 Feb;27(2):431-7.


GP 50/55, a membrane antigen of Trypanosoma cruzi involved in autoimmunity and immunosuppression.

Hernández-Munaín C, De Diego JL, Bonay P, Gironés N, Fresno M.

Biol Res. 1993;26(1-2):209-18.


Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers.

Redondo JM, Pfohl JL, Hernandez-Munain C, Wang S, Speck NA, Krangel MS.

Mol Cell Biol. 1992 Nov;12(11):4817-23.


Characterization of a glycosyl-phosphatidylinositol-anchored membrane protein from Trypanosoma cruzi.

Hernández-Munaín C, Fernández MA, Alcina A, Fresno M.

Infect Immun. 1991 Apr;59(4):1409-16.

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