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Items: 1 to 50 of 455

1.

Peptide Ligands of AmiA, AliA, and AliB Proteins Determine Pneumococcal Phenotype.

Nasher F, Aguilar F, Aebi S, Hermans PWM, Heller M, Hathaway LJ.

Front Microbiol. 2018 Dec 5;9:3013. doi: 10.3389/fmicb.2018.03013. eCollection 2018.

2.

Safety, tolerability and immunogenicity of the ExPEC4V (JNJ-63871860) vaccine for prevention of invasive extraintestinal pathogenic Escherichia coli disease: A phase 1, randomized, double-blind, placebo-controlled study in healthy Japanese participants.

Inoue M, Ogawa T, Tamura H, Hagiwara Y, Saito Y, Abbanat D, van den Dobbelsteen G, Hermans P, Thoelen S, Poolman J, Ibarra de Palacios P.

Hum Vaccin Immunother. 2018;14(9):2150-2157. doi: 10.1080/21645515.2018.1474316. Epub 2018 Jun 28.

3.

Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments.

Ereño-Orbea J, Sicard T, Cui H, Carson J, Hermans P, Julien JP.

J Mol Biol. 2018 Feb 2;430(3):322-336. doi: 10.1016/j.jmb.2017.12.010. Epub 2017 Dec 22.

PMID:
29277294
4.

Effect of N-acetylcysteine on pain in daily life in patients with sickle cell disease: a randomised clinical trial.

Sins JWR, Fijnvandraat K, Rijneveld AW, Boom MB, Kerkhoffs JH, van Meurs AH, de Groot MR, Heijboer H, Dresse MF, Lê PQ, Hermans P, Vanderfaeillie A, Van Den Neste EW, Benghiat FS, Kesse-Adu R, Delannoy A, Efira A, Azerad MA, de Borgie CA, Biemond BJ.

Br J Haematol. 2018 Aug;182(3):444-448. doi: 10.1111/bjh.14809. Epub 2017 Jun 23. No abstract available.

5.

Accelerating the clinical development of protein-based vaccines for malaria by efficient purification using a four amino acid C-terminal 'C-tag'.

Jin J, Hjerrild KA, Silk SE, Brown RE, Labbé GM, Marshall JM, Wright KE, Bezemer S, Clemmensen SB, Biswas S, Li Y, El-Turabi A, Douglas AD, Hermans P, Detmers FJ, de Jongh WA, Higgins MK, Ashfield R, Draper SJ.

Int J Parasitol. 2017 Jun;47(7):435-446. doi: 10.1016/j.ijpara.2016.12.001. Epub 2017 Jan 30.

6.

Childhood Vaccine Acceptance and Refusal among Warao Amerindian Caregivers in Venezuela; A Qualitative Approach.

Burghouts J, Del Nogal B, Uriepero A, Hermans PW, de Waard JH, Verhagen LM.

PLoS One. 2017 Jan 20;12(1):e0170227. doi: 10.1371/journal.pone.0170227. eCollection 2017.

7.

Nasopharyngeal carriage of respiratory pathogens in Warao Amerindians: significant relationship with stunting.

Verhagen LM, Hermsen M, Rivera-Olivero IA, Sisco MC, de Jonge MI, Hermans PW, de Waard JH.

Trop Med Int Health. 2017 Apr;22(4):407-414. doi: 10.1111/tmi.12835. Epub 2017 Feb 9.

8.

Introduction of the 13-valent pneumococcal conjugate vaccine in an isolated pneumococcal vaccine-naïve indigenous population.

Verhagen LM, Rivera-Olivero IA, Hermsen M, Sisco MC, Maes M, Del Nogal B, Bogaert D, Berbers GA, Hermans PW, de Jonge MI, de Waard JH.

Eur Respir J. 2016 Nov;48(5):1492-1496. doi: 10.1183/13993003.00890-2016. Epub 2016 Aug 18. No abstract available.

9.

Role of antibodies and IL17-mediated immunity in protection against pneumococcal otitis media.

Habets MN, van Selm S, van Opzeeland FJ, Simonetti E, Hermans PWM, de Jonge MI, Diavatopoulos DA.

Vaccine. 2016 Nov 21;34(48):5968-5974. doi: 10.1016/j.vaccine.2016.09.057. Epub 2016 Oct 19.

PMID:
27771185
10.

Camelid VH H affinity ligands enable separation of closely related biopharmaceuticals.

Pabst TM, Wendeler M, Wang X, Bezemer S, Hermans P, Hunter AK.

Biotechnol J. 2017 Feb;12(2). doi: 10.1002/biot.201600357. Epub 2016 Oct 20.

11.

A short-term extremely low frequency electromagnetic field exposure increases circulating leukocyte numbers and affects HPA-axis signaling in mice.

de Kleijn S, Ferwerda G, Wiese M, Trentelman J, Cuppen J, Kozicz T, de Jager L, Hermans PW, Verburg-van Kemenade BM.

Bioelectromagnetics. 2016 Oct;37(7):433-43. doi: 10.1002/bem.21998. Epub 2016 Aug 24.

12.

Stunting correlates with high salivary and serum antibody levels after 13-valent pneumococcal conjugate vaccination of Venezuelan Amerindian children.

Verhagen LM, Hermsen M, Rivera-Olivero I, Sisco MC, Pinelli E, Hermans PW, Berbers GA, de Waard JH, de Jonge MI.

Vaccine. 2016 Apr 29;34(20):2312-20. doi: 10.1016/j.vaccine.2016.03.066. Epub 2016 Mar 29.

PMID:
27036512
13.

Fine-tuning of choline metabolism is important for pneumococcal colonization.

Johnston C, Hauser C, Hermans PW, Martin B, Polard P, Bootsma HJ, Claverys JP.

Mol Microbiol. 2016 Jun;100(6):972-88. doi: 10.1111/mmi.13360. Epub 2016 Apr 6.

14.

Comparative Genomic Analyses of the Moraxella catarrhalis Serosensitive and Seroresistant Lineages Demonstrate Their Independent Evolution.

Earl JP, de Vries SP, Ahmed A, Powell E, Schultz MP, Hermans PW, Hill DJ, Zhou Z, Constantinidou CI, Hu FZ, Bootsma HJ, Ehrlich GD.

Genome Biol Evol. 2016 Apr 6;8(4):955-74. doi: 10.1093/gbe/evw039.

15.

Management and Prevention of Percutaneous Iliac Stent Infection: A Case Report.

Wissanji T, Fouard O, Herman D, Hermans P, Vindevogel C.

Ann Vasc Surg. 2016 Apr;32:131.e1-5. doi: 10.1016/j.avsg.2015.10.031. Epub 2016 Jan 29. Review.

PMID:
26827685
16.

Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia.

Hommes TJ, van Lieshout MH, van 't Veer C, Florquin S, Bootsma HJ, Hermans PW, de Vos AF, van der Poll T.

PLoS One. 2015 Dec 16;10(12):e0145138. doi: 10.1371/journal.pone.0145138. eCollection 2015.

17.

A novel quantitative PCR assay for the detection of Streptococcus pneumoniae using the competence regulator gene target comX.

Habets MN, Cremers AJ, Bos MP, Savelkoul P, Eleveld MJ, Meis JF, Hermans PW, Melchers WJ, de Jonge MI, Diavatopoulos DA.

J Med Microbiol. 2016 Feb;65(2):129-36. doi: 10.1099/jmm.0.000204. Epub 2015 Dec 1.

PMID:
26628261
18.

The post-vaccine microevolution of invasive Streptococcus pneumoniae.

Cremers AJ, Mobegi FM, de Jonge MI, van Hijum SA, Meis JF, Hermans PW, Ferwerda G, Bentley SD, Zomer AL.

Sci Rep. 2015 Oct 23;5:14952. doi: 10.1038/srep14952.

19.

Ability of Antibiotic-Resistant Nonvaccine-Type Pneumococcal Clones to Cause Otitis Media in an Infant Mouse Model of Pneumococcal-Influenza Virus Coinfection.

Frazão N, Hermans P, van Selm S, Sá-Leão R, de Lencastre H, Tomasz A, Diavatopoulos D.

Microb Drug Resist. 2016 Jan;22(1):97-101. doi: 10.1089/mdr.2015.0109. Epub 2015 Sep 14.

PMID:
26366835
20.

Development, upscaling and validation of the purification process for human-cl rhFVIII (Nuwiq®), a new generation recombinant factor VIII produced in a human cell-line.

Winge S, Yderland L, Kannicht C, Hermans P, Adema S, Schmidt T, Gilljam G, Linhult M, Tiemeyer M, Belyanskaya L, Walter O.

Protein Expr Purif. 2015 Nov;115:165-75. doi: 10.1016/j.pep.2015.08.023. Epub 2015 Aug 28.

21.

Olfactomedin 4 Serves as a Marker for Disease Severity in Pediatric Respiratory Syncytial Virus (RSV) Infection.

Brand HK, Ahout IM, de Ridder D, van Diepen A, Li Y, Zaalberg M, Andeweg A, Roeleveld N, de Groot R, Warris A, Hermans PW, Ferwerda G, Staal FJ.

PLoS One. 2015 Jul 10;10(7):e0131927. doi: 10.1371/journal.pone.0131927. eCollection 2015.

22.

The vaccine potential of Bordetella pertussis biofilm-derived membrane proteins.

de Gouw D, Serra DO, de Jonge MI, Hermans PW, Wessels HJ, Zomer A, Yantorno OM, Diavatopoulos DA, Mooi FR.

Emerg Microbes Infect. 2014 Aug;3(8):e58. doi: 10.1038/emi.2014.58. Epub 2014 Aug 20.

23.

Co-Inactivation of GlnR and CodY Regulators Impacts Pneumococcal Cell Wall Physiology.

Johnston C, Bootsma HJ, Aldridge C, Manuse S, Gisch N, Schwudke D, Hermans PW, Grangeasse C, Polard P, Vollmer W, Claverys JP.

PLoS One. 2015 Apr 22;10(4):e0123702. doi: 10.1371/journal.pone.0123702. eCollection 2015.

24.

Development of a VHH-Based Erythropoietin Quantification Assay.

Kol S, Kallehauge TB, Adema S, Hermans P.

Mol Biotechnol. 2015 Aug;57(8):692-700. doi: 10.1007/s12033-015-9860-7.

25.

The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice.

de Vos AF, Dessing MC, Lammers AJ, de Porto AP, Florquin S, de Boer OJ, de Beer R, Terpstra S, Bootsma HJ, Hermans PW, van 't Veer C, van der Poll T.

PLoS One. 2015 Feb 20;10(2):e0118181. doi: 10.1371/journal.pone.0118181. eCollection 2015.

26.

Host proteome correlates of vaccine-mediated enhanced disease in a mouse model of respiratory syncytial virus infection.

van Diepen A, Brand HK, de Waal L, Bijl M, Jong VL, Kuiken T, van Amerongen G, van den Ham HJ, Eijkemans MJ, Osterhaus AD, Hermans PW, Andeweg AC.

J Virol. 2015 May;89(9):5022-31. doi: 10.1128/JVI.03630-14. Epub 2015 Feb 18.

27.

The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition.

Cremers AJ, Zomer AL, Gritzfeld JF, Ferwerda G, van Hijum SA, Ferreira DM, Shak JR, Klugman KP, Boekhorst J, Timmerman HM, de Jonge MI, Gordon SB, Hermans PW.

Microbiome. 2014 Dec 15;2:44. doi: 10.1186/2049-2618-2-44. eCollection 2014.

28.

Global phylogenomic analysis of nonencapsulated Streptococcus pneumoniae reveals a deep-branching classic lineage that is distinct from multiple sporadic lineages.

Hilty M, Wüthrich D, Salter SJ, Engel H, Campbell S, Sá-Leão R, de Lencastre H, Hermans P, Sadowy E, Turner P, Chewapreecha C, Diggle M, Pluschke G, McGee L, Eser ÖK, Low DE, Smith-Vaughan H, Endimiani A, Küffer M, Dupasquier M, Beaudoing E, Weber J, Bruggmann R, Hanage WP, Parkhill J, Hathaway LJ, Mühlemann K, Bentley SD.

Genome Biol Evol. 2014 Dec 4;6(12):3281-94. doi: 10.1093/gbe/evu263.

29.

From microbial gene essentiality to novel antimicrobial drug targets.

Mobegi FM, van Hijum SA, Burghout P, Bootsma HJ, de Vries SP, van der Gaast-de Jongh CE, Simonetti E, Langereis JD, Hermans PW, de Jonge MI, Zomer A.

BMC Genomics. 2014 Nov 5;15:958. doi: 10.1186/1471-2164-15-958.

30.

Non-typeable pneumococci circulating in Portugal are of cps type NCC2 and have genomic features typical of encapsulated isolates.

Tavares DA, Simões AS, Bootsma HJ, Hermans PW, de Lencastre H, Sá-Leão R.

BMC Genomics. 2014 Oct 6;15:863. doi: 10.1186/1471-2164-15-863.

31.

Proteomics-identified Bvg-activated autotransporters protect against bordetella pertussis in a mouse model.

de Gouw D, de Jonge MI, Hermans PW, Wessels HJ, Zomer A, Berends A, Pratt C, Berbers GA, Mooi FR, Diavatopoulos DA.

PLoS One. 2014 Aug 18;9(8):e105011. doi: 10.1371/journal.pone.0105011. eCollection 2014. Erratum in: PLoS One. 2014 Nov;9(11):e113322. Gouw, Daan de [corrected to de Gouw, Daan; Jonge, Marien I de [corrected to de Jonge, Marien I].

32.

Development of a novel affinity chromatography resin for platform purification of lambda fabs.

Eifler N, Medaglia G, Anderka O, Laurin L, Hermans P.

Biotechnol Prog. 2014 Nov-Dec;30(6):1311-8. doi: 10.1002/btpr.1958. Epub 2014 Aug 6.

PMID:
25082738
33.

Agreement between QuantiFERON®-TB Gold In-Tube and the tuberculin skin test and predictors of positive test results in Warao Amerindian pediatric tuberculosis contacts.

Verhagen LM, Maes M, Villalba JA, d'Alessandro A, Rodriguez LP, España MF, Hermans PW, de Waard JH.

BMC Infect Dis. 2014 Jul 11;14:383. doi: 10.1186/1471-2334-14-383.

34.

Density and duration of experimental human pneumococcal carriage.

Gritzfeld JF, Cremers AJ, Ferwerda G, Ferreira DM, Kadioglu A, Hermans PW, Gordon SB.

Clin Microbiol Infect. 2014 Dec;20(12):O1145-51. doi: 10.1111/1469-0691.12752. Epub 2014 Aug 11.

35.

Impact of experimental human pneumococcal carriage on nasopharyngeal bacterial densities in healthy adults.

Shak JR, Cremers AJ, Gritzfeld JF, de Jonge MI, Hermans PW, Vidal JE, Klugman KP, Gordon SB.

PLoS One. 2014 Jun 10;9(6):e98829. doi: 10.1371/journal.pone.0098829. eCollection 2014.

36.

Recurrent wheezing is associated with intestinal protozoan infections in Warao Amerindian children in Venezuela: a cross-sectional survey.

Overeem MM, Verhagen LM, Hermans PW, del Nogal B, Sánchez AM, Acevedo NM, Murga RR, Roelfsema J, Pinelli E, de Waard JH.

BMC Infect Dis. 2014 May 29;14:293. doi: 10.1186/1471-2334-14-293.

37.

Immunogenicity of a 7-valent pneumococcal conjugate vaccine (PCV7) and impact on carriage in Venezuelan children at risk of invasive pneumococcal diseases.

Rivera-Olivero IA, Del Nogal B, Fuentes M, Cortez R, Bogaert D, Hermans PW, Waard JH.

Vaccine. 2014 Jun 30;32(31):4006-11. doi: 10.1016/j.vaccine.2014.04.027. Epub 2014 May 14.

PMID:
24837505
38.

Effects of 7-valent pneumococcal conjugate 1 vaccine on the severity of adult 2 bacteremic pneumococcal pneumonia.

Cremers AJ, Meis JF, Walraven G, Jongh CE, Ferwerda G, Hermans PW.

Vaccine. 2014 Jun 30;32(31):3989-94. doi: 10.1016/j.vaccine.2014.04.089. Epub 2014 May 6.

PMID:
24814555
39.

Avidity of antibodies against infecting pneumococcal serotypes increases with age and severity of disease.

Cremers AJ, Lut J, Hermans PW, Meis JF, de Jonge MI, Ferwerda G.

Clin Vaccine Immunol. 2014 Jun;21(6):904-7. doi: 10.1128/CVI.00147-14. Epub 2014 Apr 23.

40.

Effect of antibiotic streamlining on patient outcome in pneumococcal bacteraemia.

Cremers AJ, Sprong T, Schouten JA, Walraven G, Hermans PW, Meis JF, Ferwerda G.

J Antimicrob Chemother. 2014 Aug;69(8):2258-64. doi: 10.1093/jac/dku109. Epub 2014 Apr 11.

PMID:
24729585
41.

PCR deduction of invasive and colonizing pneumococcal serotypes from Venezuela: a critical appraisal.

Bello Gonzalez T, Rivera-Olivero IA, Sisco MC, Spadola E, Hermans PW, de Waard JH.

J Infect Dev Ctries. 2014 Apr 15;8(4):469-73. doi: 10.3855/jidc.3274.

42.

Genome-wide identification of genes essential for the survival of Streptococcus pneumoniae in human saliva.

Verhagen LM, de Jonge MI, Burghout P, Schraa K, Spagnuolo L, Mennens S, Eleveld MJ, van der Gaast-de Jongh CE, Zomer A, Hermans PW, Bootsma HJ.

PLoS One. 2014 Feb 25;9(2):e89541. doi: 10.1371/journal.pone.0089541. eCollection 2014.

43.

Full-gene sequencing analysis of NAT2 and its relationship with isoniazid pharmacokinetics in Venezuelan children with tuberculosis.

Verhagen LM, Coenen MJ, López D, García JF, de Waard JH, Schijvenaars MM, Hermans PW, Aarnoutse RE.

Pharmacogenomics. 2014 Feb;15(3):285-96. doi: 10.2217/pgs.13.230.

PMID:
24533708
44.

Purification of antibodies and antibody fragments using CaptureSelect™ affinity resins.

Hermans P, Adams H, Detmers F.

Methods Mol Biol. 2014;1131:297-314. doi: 10.1007/978-1-62703-992-5_19.

PMID:
24515474
45.

Nasopharyngeal carriage of Streptococcus pneumonia in pneumonia-prone age groups in Semarang, Java Island, Indonesia.

Farida H, Severin JA, Gasem MH, Keuter M, Wahyono H, van den Broek P, Hermans PW, Verbrugh HA.

PLoS One. 2014 Jan 31;9(1):e87431. doi: 10.1371/journal.pone.0087431. eCollection 2014.

46.

Incorporation of phosphorylcholine into the lipooligosaccharide of nontypeable Haemophilus influenzae does not correlate with the level of biofilm formation in vitro.

Puig C, Marti S, Hermans PW, de Jonge MI, Ardanuy C, Liñares J, Langereis JD.

Infect Immun. 2014 Apr;82(4):1591-9. doi: 10.1128/IAI.01445-13. Epub 2014 Jan 22.

47.

Diagnostic value of serum pneumococcal DNA load during invasive pneumococcal infections.

Cremers AJ, Hagen F, Hermans PW, Meis JF, Ferwerda G.

Eur J Clin Microbiol Infect Dis. 2014 Jul;33(7):1119-24. doi: 10.1007/s10096-014-2050-x. Epub 2014 Jan 22.

PMID:
24449347
48.

Differentially expressed genes in Bordetella pertussis strains belonging to a lineage which recently spread globally.

de Gouw D, Hermans PW, Bootsma HJ, Zomer A, Heuvelman K, Diavatopoulos DA, Mooi FR.

PLoS One. 2014 Jan 8;9(1):e84523. doi: 10.1371/journal.pone.0084523. eCollection 2014. Erratum in: PLoS One. 2014;9(1). doi: 10.1371/annotation/1b2cfe52-aaea-4148-aa72-a74c78550192.

49.

Deciphering the genetic basis of Moraxella catarrhalis complement resistance: a critical role for the disulphide bond formation system.

de Vries SP, Rademakers RJ, van der Gaast-de Jongh CE, Eleveld MJ, Hermans PW, Bootsma HJ.

Mol Microbiol. 2014 Feb;91(3):522-37. doi: 10.1111/mmi.12475. Epub 2013 Dec 18.

50.

Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.

de Stoppelaar SF, Bootsma HJ, Zomer A, Roelofs JJ, Hermans PW, van 't Veer C, van der Poll T.

PLoS One. 2013 Nov 11;8(11):e80062. doi: 10.1371/journal.pone.0080062. eCollection 2013.

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