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Items: 1 to 50 of 241

1.

FoxP3 deficiency causes no inflammation or neurodegeneration in the murine brain.

Gingele S, Pul R, Sardari M, Borbor M, Henkel F, Moellenkamp TM, Gudi V, Happle C, Grychtol R, Habener A, Hansen G, Hermann DM, Stangel M, Kleinschnitz C, Skuljec J.

J Neuroimmunol. 2020 Mar 18;342:577216. doi: 10.1016/j.jneuroim.2020.577216. [Epub ahead of print]

PMID:
32199198
2.

Association of social relationships with incident cardiovascular events and all-cause mortality.

Gronewold J, Kropp R, Lehmann N, Schmidt B, Weyers S, Siegrist J, Dragano N, Jöckel KH, Erbel R, Hermann DM; Heinz Nixdorf Recall Study Investigative Group.

Heart. 2020 Mar 12. pii: heartjnl-2019-316250. doi: 10.1136/heartjnl-2019-316250. [Epub ahead of print]

3.

Dose-Dependent Microglial and Astrocytic Responses Associated With Post-ischemic Neuroprotection After Lipopolysaccharide-Induced Sepsis-Like State in Mice.

Sardari M, Dzyubenko E, Schmermund B, Yin D, Qi Y, Kleinschnitz C, Hermann DM.

Front Cell Neurosci. 2020 Feb 12;14:26. doi: 10.3389/fncel.2020.00026. eCollection 2020.

4.

Safety and efficacy of GABAA α5 antagonist S44819 in patients with ischaemic stroke: a multicentre, double-blind, randomised, placebo-controlled trial.

Chabriat H, Bassetti CL, Marx U, Audoli-Inthavong ML, Sors A, Lambert E, Wattez M, Hermann DM; RESTORE BRAIN study investigators.

Lancet Neurol. 2020 Mar;19(3):226-233. doi: 10.1016/S1474-4422(20)30004-1.

PMID:
32085836
5.

Clinical and functional patient characteristics predict medical needs in older patients at risk of functional decline.

Scharf AC, Gronewold J, Dahlmann C, Schlitzer J, Kribben A, Gerken G, Frohnhofen H, Dodel R, Hermann DM.

BMC Geriatr. 2020 Feb 21;20(1):75. doi: 10.1186/s12877-020-1443-1.

6.

Randomized Efficacy and Safety Trial with Oral S 44819 after Recent ischemic cerebral Event (RESTORE BRAIN study): a placebo controlled phase II study.

Chabriat H, Bassetti CL, Marx U, Picarel-Blanchot F, Sors A, Gruget C, Saba B, Wattez M, Audoli ML, Hermann DM.

Trials. 2020 Feb 3;21(1):136. doi: 10.1186/s13063-020-4072-2.

7.

Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis.

Thiele Née Schrewe L, Guse K, Tietz S, Remlinger J, Demir S, Pedreiturria X, Hoepner R, Salmen A, Pistor M, Turner T, Engelhardt B, Hermann DM, Lühder F, Wiese S, Chan A.

J Neuroinflammation. 2020 Jan 8;17(1):9. doi: 10.1186/s12974-019-1677-z.

8.

Toxicity and health impact of nanoparticles. Basic biology and clinical perspective.

Olaru DG, Olaru A, Kassem GH, Popescu-Drigă MV, Pinoşanu LR, Dumitraşcu DI, Popescu EL, Hermann DM, Popa-Wagner A.

Rom J Morphol Embryol. 2019;60(3):787-792.

9.

CCL11 Differentially Affects Post-Stroke Brain Injury and Neuroregeneration in Mice Depending on Age.

Lieschke S, Zechmeister B, Haupt M, Zheng X, Jin F, Hein K, Weber MS, Hermann DM, Bähr M, Kilic E, Doeppner TR.

Cells. 2019 Dec 26;9(1). pii: E66. doi: 10.3390/cells9010066.

10.

Very Low Efficiency of Direct Reprogramming of Astrocytes Into Neurons in the Brains of Young and Aged Mice After Cerebral Ischemia.

Gresita A, Glavan D, Udristoiu I, Catalin B, Hermann DM, Popa-Wagner A.

Front Aging Neurosci. 2019 Dec 3;11:334. doi: 10.3389/fnagi.2019.00334. eCollection 2019.

11.

Opportunities and Limitations of Vascular Risk Factor Models in Studying Plasticity-Promoting and Restorative Ischemic Stroke Therapies.

Hermann DM, Doeppner TR, Popa-Wagner A.

Neural Plast. 2019 Nov 11;2019:9785476. doi: 10.1155/2019/9785476. eCollection 2019. Review.

12.

Intracortical Administration of the Complement C3 Receptor Antagonist Trifluoroacetate Modulates Microglia Reaction after Brain Injury.

Surugiu R, Catalin B, Dumbrava D, Gresita A, Olaru DG, Hermann DM, Popa-Wagner A.

Neural Plast. 2019 Nov 14;2019:1071036. doi: 10.1155/2019/1071036. eCollection 2019.

13.

Recent Advances in Mono- and Combined Stem Cell Therapies of Stroke in Animal Models and Humans.

Surugiu R, Olaru A, Hermann DM, Glavan D, Catalin B, Popa-Wagner A.

Int J Mol Sci. 2019 Nov 29;20(23). pii: E6029. doi: 10.3390/ijms20236029. Review.

14.

The Acid Sphingomyelinase/ Ceramide System as Target for Ischemic Stroke Therapies.

Mohamud Yusuf A, Hagemann N, Hermann DM.

Neurosignals. 2019;27(S1):32-43. doi: 10.33594/000000184.

15.

Correction to: Genetic conversion of proliferative astroglia into neurons after cerebral ischemia: a new therapeutic tool for the aged brain?

Popa-Wagner A, Hermann DM, Gresita A.

Geroscience. 2020 Feb;42(1):373. doi: 10.1007/s11357-019-00136-5.

16.

Cardiovascular Risk and Atherosclerosis Progression in Hypertensive Persons Treated to Blood Pressure Targets.

Gronewold J, Kropp R, Lehmann N, Stang A, Mahabadi AA, Kälsch H, Weimar C, Dichgans M, Budde T, Moebus S, Jöckel KH, Erbel R, Hermann DM.

Hypertension. 2019 Dec;74(6):1436-1447. doi: 10.1161/HYPERTENSIONAHA.119.13827. Epub 2019 Nov 4.

PMID:
31679426
17.

Deactivation of ATP-Binding Cassette Transporters ABCB1 and ABCC1 Does Not Influence Post-ischemic Neurological Deficits, Secondary Neurodegeneration and Neurogenesis, but Induces Subtle Microglial Morphological Changes.

Manrique-Castano D, Sardari M, Silva de Carvalho T, Doeppner TR, Popa-Wagner A, Kleinschnitz C, Chan A, Hermann DM.

Front Cell Neurosci. 2019 Sep 12;13:412. doi: 10.3389/fncel.2019.00412. eCollection 2019.

18.

A novel V272D presenilin mutation associated with logopenia, disorientation, and apraxia in an autosomal-dominant Alzheimer's disease family.

Mengel D, Liu L, Yamamoto R, Zülow S, Deuschl C, Hermann DM, Zerr I, Selkoe DJ, Dodel R.

Neurobiol Aging. 2020 Jan;85:154.e5-154.e7. doi: 10.1016/j.neurobiolaging.2019.07.002. Epub 2019 Aug 7.

PMID:
31500908
19.

Health outcome of older hospitalized patients in internal medicine environments evaluated by Identification of Seniors at Risk (ISAR) screening and geriatric assessment.

Scharf AC, Gronewold J, Dahlmann C, Schlitzer J, Kribben A, Gerken G, Rassaf T, Kleinschnitz C, Dodel R, Frohnhofen H, Hermann DM.

BMC Geriatr. 2019 Aug 14;19(1):221. doi: 10.1186/s12877-019-1239-3.

20.

Validity and Reliability of Neurological Scores in Mice Exposed to Middle Cerebral Artery Occlusion.

Bieber M, Gronewold J, Scharf AC, Schuhmann MK, Langhauser F, Hopp S, Mencl S, Geuss E, Leinweber J, Guthmann J, Doeppner TR, Kleinschnitz C, Stoll G, Kraft P, Hermann DM.

Stroke. 2019 Oct;50(10):2875-2882. doi: 10.1161/STROKEAHA.119.026652. Epub 2019 Aug 15.

PMID:
31412755
21.

Contribution of polymorphonuclear neutrophils in the blood periphery to ischemic brain injury.

Hermann DM, Gunzer M.

Neurol Neuroimmunol Neuroinflamm. 2019 May 15;6(4):e570. doi: 10.1212/NXI.0000000000000570. eCollection 2019 Jul. No abstract available.

22.

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis.

Meiners J, Palmieri V, Klopfleisch R, Ebel JF, Japtok L, Schumacher F, Yusuf AM, Becker KA, Zöller J, Hose M, Kleuser B, Hermann DM, Kolesnick RN, Buer J, Hansen W, Westendorf AM.

Front Immunol. 2019 Jun 19;10:1386. doi: 10.3389/fimmu.2019.01386. eCollection 2019.

23.

Moderate Protein Restriction Protects Against Focal Cerebral Ischemia in Mice by Mechanisms Involving Anti-inflammatory and Anti-oxidant Responses.

de Carvalho TS, Sanchez-Mendoza EH, Nascentes LM, Schultz Moreira AR, Sardari M, Dzyubenko E, Kleinschnitz C, Hermann DM.

Mol Neurobiol. 2019 Dec;56(12):8477-8488. doi: 10.1007/s12035-019-01679-6. Epub 2019 Jul 1.

24.

Publisher Correction: Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response.

Merz SF, Korste S, Bornemann L, Michel L, Stock P, Squire A, Soun C, Engel DR, Detzer J, Lörchner H, Hermann DM, Kamler M, Klode J, Hendgen-Cotta UB, Rassaf T, Gunzer M, Totzeck M.

Nat Commun. 2019 Jun 19;10(1):2768. doi: 10.1038/s41467-019-10804-x.

25.

Identification of the right cell sources for the production of therapeutically active extracellular vesicles in ischemic stroke.

Giebel B, Hermann DM.

Ann Transl Med. 2019 May;7(9):188. doi: 10.21037/atm.2019.03.49. No abstract available.

26.

Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response.

Merz SF, Korste S, Bornemann L, Michel L, Stock P, Squire A, Soun C, Engel DR, Detzer J, Lörchner H, Hermann DM, Kamler M, Klode J, Hendgen-Cotta UB, Rassaf T, Gunzer M, Totzeck M.

Nat Commun. 2019 May 24;10(1):2312. doi: 10.1038/s41467-019-10338-2. Erratum in: Nat Commun. 2019 Jun 19;10(1):2768.

27.

Preclinical concepts and results with the GABAA antagonist S44819 in a mouse model of middle cerebral artery occlusion.

Hermann DM, Saba B, Sors A, Bassetti CL.

Neural Regen Res. 2019 Sep;14(9):1517-1518. doi: 10.4103/1673-5374.255963. No abstract available.

28.

Acute and Post-acute Neuromodulation Induces Stroke Recovery by Promoting Survival Signaling, Neurogenesis, and Pyramidal Tract Plasticity.

Caglayan AB, Beker MC, Caglayan B, Yalcin E, Caglayan A, Yulug B, Hanoglu L, Kutlu S, Doeppner TR, Hermann DM, Kilic E.

Front Cell Neurosci. 2019 Apr 12;13:144. doi: 10.3389/fncel.2019.00144. eCollection 2019.

29.

Modeling Vascular Risk Factors for the Development of Ischemic Stroke Therapies.

Hermann DM, Kleinschnitz C.

Stroke. 2019 May;50(5):1310-1317. doi: 10.1161/STROKEAHA.118.024673. Review. No abstract available.

PMID:
30896361
30.

Neuroprotection Induced by Energy and Protein-Energy Undernutrition Is Phase-Dependent After Focal Cerebral Ischemia in Mice.

de Carvalho TS, Sanchez-Mendoza EH, Nascentes Melo LM, Schultz Moreira AR, Sardari M, Dzyubenko E, Kleinschnitz C, Hermann DM.

Transl Stroke Res. 2020 Feb;11(1):135-146. doi: 10.1007/s12975-019-00700-3. Epub 2019 Mar 18.

31.

Sleep-Disordered Breathing in Hospitalized Geriatric Patients with Mild Dementia and Its Association with Cognition, Emotion and Mobility.

Gronewold J, Haensel R, Kleinschnitz C, Frohnhofen H, Hermann DM.

Int J Environ Res Public Health. 2019 Mar 9;16(5). pii: E863. doi: 10.3390/ijerph16050863.

32.

Animal models of ischemic stroke and their impact on drug discovery.

Hermann DM, Popa-Wagner A, Kleinschnitz C, Doeppner TR.

Expert Opin Drug Discov. 2019 Mar;14(3):315-326. doi: 10.1080/17460441.2019.1573984. Epub 2019 Feb 4. Review.

PMID:
30714423
33.

Polymorphonuclear Neutrophils Play a Decisive Role for Brain Injury and Neurological Recovery Poststroke.

Hermann DM, Gunzer M.

Stroke. 2019 Mar;50(3):e40-e41. doi: 10.1161/STROKEAHA.118.021564. No abstract available.

PMID:
30674233
34.

Impairment of hypoxia-induced angiogenesis by LDL involves a HIF-centered signaling network linking inflammatory TNFα and angiogenic VEGF.

Jin F, Zheng X, Yang Y, Yao G, Ye L, Doeppner TR, Hermann DM, Wang H, Dai Y.

Aging (Albany NY). 2019 Jan 18;11(2):328-349. doi: 10.18632/aging.101726.

35.

Role of immune responses for extracellular matrix remodeling in the ischemic brain.

Dzyubenko E, Manrique-Castano D, Kleinschnitz C, Faissner A, Hermann DM.

Ther Adv Neurol Disord. 2018 Dec 17;11:1756286418818092. doi: 10.1177/1756286418818092. eCollection 2018. Review.

36.

Multicellular Crosstalk Between Exosomes and the Neurovascular Unit After Cerebral Ischemia. Therapeutic Implications.

Zagrean AM, Hermann DM, Opris I, Zagrean L, Popa-Wagner A.

Front Neurosci. 2018 Nov 6;12:811. doi: 10.3389/fnins.2018.00811. eCollection 2018. Review.

37.

Very Delayed Remote Ischemic Post-conditioning Induces Sustained Neurological Recovery by Mechanisms Involving Enhanced Angioneurogenesis and Peripheral Immunosuppression Reversal.

Doeppner TR, Zechmeister B, Kaltwasser B, Jin F, Zheng X, Majid A, Venkataramani V, Bähr M, Hermann DM.

Front Cell Neurosci. 2018 Oct 29;12:383. doi: 10.3389/fncel.2018.00383. eCollection 2018.

38.

Precipitation with polyethylene glycol followed by washing and pelleting by ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small and large scales.

Ludwig AK, De Miroschedji K, Doeppner TR, Börger V, Ruesing J, Rebmann V, Durst S, Jansen S, Bremer M, Behrmann E, Singer BB, Jastrow H, Kuhlmann JD, El Magraoui F, Meyer HE, Hermann DM, Opalka B, Raunser S, Epple M, Horn PA, Giebel B.

J Extracell Vesicles. 2018 Oct 17;7(1):1528109. doi: 10.1080/20013078.2018.1528109. eCollection 2018.

39.

Postacute Delivery of GABAA α5 Antagonist Promotes Postischemic Neurological Recovery and Peri-infarct Brain Remodeling.

Wang YC, Dzyubenko E, Sanchez-Mendoza EH, Sardari M, Silva de Carvalho T, Doeppner TR, Kaltwasser B, Machado P, Kleinschnitz C, Bassetti CL, Hermann DM.

Stroke. 2018 Oct;49(10):2495-2503. doi: 10.1161/STROKEAHA.118.021378.

40.

Role of polymorphonuclear neutrophils in the reperfused ischemic brain: insights from cell-type-specific immunodepletion and fluorescence microscopy studies.

Hermann DM, Kleinschnitz C, Gunzer M.

Ther Adv Neurol Disord. 2018 Sep 14;11:1756286418798607. doi: 10.1177/1756286418798607. eCollection 2018. Review.

41.

Topological remodeling of cortical perineuronal nets in focal cerebral ischemia and mild hypoperfusion.

Dzyubenko E, Manrique-Castano D, Kleinschnitz C, Faissner A, Hermann DM.

Matrix Biol. 2018 Dec;74:121-132. doi: 10.1016/j.matbio.2018.08.001. Epub 2018 Aug 6.

42.

Immunological and non-immunological effects of stem cell-derived extracellular vesicles on the ischaemic brain.

Doeppner TR, Bähr M, Giebel B, Hermann DM.

Ther Adv Neurol Disord. 2018 Jul 26;11:1756286418789326. doi: 10.1177/1756286418789326. eCollection 2018. Review.

43.

Implications of polymorphonuclear neutrophils for ischemic stroke and intracerebral hemorrhage: Predictive value, pathophysiological consequences and utility as therapeutic target.

Hermann DM, Kleinschnitz C, Gunzer M.

J Neuroimmunol. 2018 Aug 15;321:138-143. doi: 10.1016/j.jneuroim.2018.04.015. Epub 2018 Apr 24. Review.

PMID:
29729895
44.

Defining mechanisms of neural plasticity after brainstem ischemia in rats.

Minnerup J, Strecker JK, Wachsmuth L, Hoppen M, Schmidt A, Hermann DM, Wiendl H, Meuth S, Faber C, Diederich K, Schäbitz WR.

Ann Neurol. 2018 May;83(5):1003-1015. doi: 10.1002/ana.25238. Epub 2018 May 11.

PMID:
29665155
45.

Higher levels of kallikrein-8 in female brain may increase the risk for Alzheimer's disease.

Keyvani K, Münster Y, Kurapati NK, Rubach S, Schönborn A, Kocakavuk E, Karout M, Hammesfahr P, Wang YC, Hermann DM, Teuber-Hanselmann S, Herring A.

Brain Pathol. 2018 Nov;28(6):947-964. doi: 10.1111/bpa.12599. Epub 2018 Apr 10.

PMID:
29505099
46.

High-density lipoprotein (HDL) promotes angiogenesis via S1P3-dependent VEGFR2 activation.

Jin F, Hagemann N, Sun L, Wu J, Doeppner TR, Dai Y, Hermann DM.

Angiogenesis. 2018 May;21(2):381-394. doi: 10.1007/s10456-018-9603-z. Epub 2018 Feb 15.

PMID:
29450744
47.

Identification of the histone lysine demethylase KDM4A/JMJD2A as a novel epigenetic target in M1 macrophage polarization induced by oxidized LDL.

Wang X, Wang S, Yao G, Yu D, Chen K, Tong Q, Ye L, Wu C, Sun Y, Li H, Hermann DM, Doeppner TR, Jin F, Dai Y, Wu J.

Oncotarget. 2017 May 10;8(70):114442-114456. doi: 10.18632/oncotarget.17748. eCollection 2017 Dec 29.

48.

Identification of hospitalized elderly patients at risk for adverse in-hospital outcomes in a university orthopedics and trauma surgery environment.

Gronewold J, Dahlmann C, Jäger M, Hermann DM.

PLoS One. 2017 Nov 10;12(11):e0187801. doi: 10.1371/journal.pone.0187801. eCollection 2017.

49.

Concise Review: Extracellular Vesicles Overcoming Limitations of Cell Therapies in Ischemic Stroke.

Doeppner TR, Bähr M, Hermann DM, Giebel B.

Stem Cells Transl Med. 2017 Nov;6(11):2044-2052. doi: 10.1002/sctm.17-0081. Epub 2017 Sep 23. Review.

50.

Biochemical markers in vascular cognitive impairment associated with subcortical small vessel disease - A consensus report.

Wallin A, Kapaki E, Boban M, Engelborghs S, Hermann DM, Huisa B, Jonsson M, Kramberger MG, Lossi L, Malojcic B, Mehrabian S, Merighi A, Mukaetova-Ladinska EB, Paraskevas GP, Popescu BO, Ravid R, Traykov L, Tsivgoulis G, Weinstein G, Korczyn A, Bjerke M, Rosenberg G.

BMC Neurol. 2017 May 23;17(1):102. doi: 10.1186/s12883-017-0877-3. Review.

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