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Impact of EMA regulatory label changes on systemic diclofenac initiation, discontinuation, and switching to other pain medicines in Scotland, England, Denmark, and The Netherlands.

Morales DR, Morant SV, MacDonald TM, Mackenzie IS, Doney ASF, Mitchell L, Bennie M, Robertson C, Hallas J, Pottegard A, Ernst MT, Wei L, Nicholson L, Morris C, Herings RMC, Overbeek JA, Smits E, Flynn RWV.

Pharmacoepidemiol Drug Saf. 2020 Jan 3. doi: 10.1002/pds.4955. [Epub ahead of print]


Trends in mortality, cardiovascular complications, and risk factors in type 2 diabetes.

Heintjes EM, Houben E, Beekman-Hendriks WL, Lighaam E, Cremers SM, Penning-van Beest FJA, Stehouwer CDA, Herings RMC.

Neth J Med. 2019 Dec;77(9):317-329.


Methylphenidate Treatment Initiated During Childhood Is Continued in Adulthood in Half of the Study Population.

Cheung K, Verhamme KMC, Herings R, Visser LE, Stricker BH.

J Child Adolesc Psychopharmacol. 2019 Aug;29(6):426-432. doi: 10.1089/cap.2018.0170. Epub 2019 Jun 3.


Type 2 Diabetes, but Not Insulin (Analog) Treatment, Is Associated With More Advanced Stages of Breast Cancer: A National Linkage of Cancer and Pharmacy Registries.

Overbeek JA, van Herk-Sukel MPP, Vissers PAJ, van der Heijden AAWA, Bronsveld HK, Herings RMC, Schmidt MK, Nijpels G.

Diabetes Care. 2019 Mar;42(3):434-442. doi: 10.2337/dc18-2146. Epub 2019 Jan 24.


How representative of a general type 2 diabetes population are patients included in cardiovascular outcome trials with SGLT2 inhibitors? A large European observational study.

Birkeland KI, Bodegard J, Norhammar A, Kuiper JG, Georgiado E, Beekman-Hendriks WL, Thuresson M, Pignot M, Herings RMC, Kooy A.

Diabetes Obes Metab. 2018 Dec 9. doi: 10.1111/dom.13612. [Epub ahead of print]


Compliance with the guidelines for laboratory monitoring of patients treated with lithium: A retrospective follow-up study among ambulatory patients in the Netherlands.

Nederlof M, Egberts TC, van Londen L, de Rotte MC, Souverein PC, Herings RM, Heerdink ER.

Bipolar Disord. 2019 Aug;21(5):419-427. doi: 10.1111/bdi.12730. Epub 2019 Jan 2.


Sex- and site-specific differences in colorectal cancer risk among people with type 2 diabetes.

Overbeek JA, Kuiper JG, van der Heijden AAWA, Labots M, Haug U, Herings RMC, Nijpels G.

Int J Colorectal Dis. 2019 Feb;34(2):269-276. doi: 10.1007/s00384-018-3191-7. Epub 2018 Nov 12.


Risk of acute myocardial infarction during use of individual NSAIDs: A nested case-control study from the SOS project.

Masclee GMC, Straatman H, Arfè A, Castellsague J, Garbe E, Herings R, Kollhorst B, Lucchi S, Perez-Gutthann S, Romio S, Schade R, Schink T, Schuemie MJ, Scotti L, Varas-Lorenzo C, Valkhoff VE, Villa M, Sturkenboom MCJM.

PLoS One. 2018 Nov 1;13(11):e0204746. doi: 10.1371/journal.pone.0204746. eCollection 2018.


Risk of ischemic stroke and the use of individual non-steroidal anti-inflammatory drugs: A multi-country European database study within the SOS Project.

Schink T, Kollhorst B, Varas Lorenzo C, Arfè A, Herings R, Lucchi S, Romio S, Schade R, Schuemie MJ, Straatman H, Valkhoff V, Villa M, Sturkenboom M, Garbe E.

PLoS One. 2018 Sep 19;13(9):e0203362. doi: 10.1371/journal.pone.0203362. eCollection 2018.


Can Electronic Health Records Databases Complement Spontaneous Reporting System Databases? A Historical-Reconstruction of the Association of Rofecoxib and Acute Myocardial Infarction.

Patadia VK, Schuemie MJ, Coloma PM, Herings R, van der Lei J, Sturkenboom M, Trifirò G.

Front Pharmacol. 2018 Jun 6;9:594. doi: 10.3389/fphar.2018.00594. eCollection 2018.


Clinical effectiveness of liraglutide vs basal insulin in a real-world setting: Evidence of improved glycaemic and weight control in obese people with type 2 diabetes.

Overbeek JA, Heintjes EM, Huisman EL, Tikkanen CK, van Diermen AW, Penning-van Beest FJA, Herings RMC.

Diabetes Obes Metab. 2018 Sep;20(9):2093-2102. doi: 10.1111/dom.13335. Epub 2018 May 29.


Risk of dipeptidyl peptidase-4 (DPP-4) inhibitors on site-specific cancer: A systematic review and meta-analysis.

Overbeek JA, Bakker M, van der Heijden AAWA, van Herk-Sukel MPP, Herings RMC, Nijpels G.

Diabetes Metab Res Rev. 2018 Jul;34(5):e3004. doi: 10.1002/dmrr.3004. Epub 2018 Apr 26. Review.


Brand and generic use of inhalation medication and frequency of switching in children and adults: A population-based cohort study.

Engelkes M, van Blijderveen JC, Overbeek JA, Kuiper J, Herings RCM, Sturkenboom MCJM, de Jongste JC, Verhamme KMC, Janssens HM.

J Asthma. 2018 Oct;55(10):1086-1094. doi: 10.1080/02770903.2017.1396468. Epub 2017 Nov 29.


Observational cohort study: safety outcomes in children using proton pump inhibitors or histamine-2 receptor antagonists.

Houben E, Johansson S, Nagy P, Penning-van Beest FJA, Kuipers EJ, Herings RMC.

Curr Med Res Opin. 2018 Apr;34(4):577-583. doi: 10.1080/03007995.2017.1407302. Epub 2017 Nov 24.


Changes in glucose-lowering drug use before and after cancer diagnosis in patients with diabetes.

Zanders MMJ, Haak HR, van Herk-Sukel MPP, Herings RMC, van de Poll-Franse LV, Johnson JA.

Diabetes Metab. 2018 Feb;44(1):22-29. doi: 10.1016/j.diabet.2017.08.004. Epub 2017 Oct 22.


No Evidence for an Association Between Renal Function and Serious Bleeding Events in Patients Treated With Coumarins: A Population-Based Study.

Houben E, Smits E, Overbeek JA, Penning-van Beest FJA, Herings RMC, van Herk-Sukel MPP, Teichert M, de Smet PAGM.

Ann Pharmacother. 2018 Mar;52(3):221-234. doi: 10.1177/1060028017735340. Epub 2017 Oct 6.


Thrombotic risk minimization for Diane-35 and generics.

Bezemer ID, Smits E, Penning-van Beest FJA, Asiimwe A, Herings RMC.

Pharmacoepidemiol Drug Saf. 2017 Nov;26(11):1411-1417. doi: 10.1002/pds.4319. Epub 2017 Sep 26.


Relation Between Different Measures of Glycemic Exposure and Microvascular and Macrovascular Complications in Patients with Type 2 Diabetes Mellitus: An Observational Cohort Study.

van Wijngaarden RPT, Overbeek JA, Heintjes EM, Schubert A, Diels J, Straatman H, Steyerberg EW, Herings RMC.

Diabetes Ther. 2017 Oct;8(5):1097-1109. doi: 10.1007/s13300-017-0301-4. Epub 2017 Sep 18.


Characteristics of children and adolescents first prescribed proton pump inhibitors or histamine-2-receptor antagonists: an observational cohort study.

Ruigómez A, Kool-Houweling LMA, García Rodríguez LA, Penning-van Beest FJA, Herings RMC.

Curr Med Res Opin. 2017 Dec;33(12):2251-2259. doi: 10.1080/03007995.2017.1336083. Epub 2017 Jun 9.


Statin Use After Diagnosis of Colon Cancer and Patient Survival.

Voorneveld PW, Reimers MS, Bastiaannet E, Jacobs RJ, van Eijk R, Zanders MMJ, Herings RMC, van Herk-Sukel MPP, Kodach LL, van Wezel T, Kuppen PJK, Morreau H, van de Velde CJH, Hardwick JCH, Liefers GJ.

Gastroenterology. 2017 Aug;153(2):470-479.e4. doi: 10.1053/j.gastro.2017.05.011. Epub 2017 May 13.


An evaluation of exact matching and propensity score methods as applied in a comparative effectiveness study of inhaled corticosteroids in asthma.

Burden A, Roche N, Miglio C, Hillyer EV, Postma DS, Herings RM, Overbeek JA, Khalid JM, van Eickels D, Price DB.

Pragmat Obs Res. 2017 Mar 22;8:15-30. doi: 10.2147/POR.S122563. eCollection 2017.


Use of Lipid-modifying Therapy and LDL-C Goal Attainment in a High-Cardiovascular-Risk Population in the Netherlands.

Kuiper JG, Sanchez RJ, Houben E, Heintjes EM, Penning-van Beest FJA, Khan I, van Riemsdijk M, Herings RMC.

Clin Ther. 2017 Apr;39(4):819-827.e1. doi: 10.1016/j.clinthera.2017.03.001. Epub 2017 Mar 27.


Type 2 Diabetes Mellitus Treatment Patterns Across Europe: A Population-based Multi-database Study.

Overbeek JA, Heintjes EM, Prieto-Alhambra D, Blin P, Lassalle R, Hall GC, Lapi F, Bianchini E, Hammar N, Bezemer ID, Herings RMC.

Clin Ther. 2017 Apr;39(4):759-770. doi: 10.1016/j.clinthera.2017.02.008. Epub 2017 Mar 23.


Asthma-Related Outcomes in Patients Initiating Extrafine Ciclesonide or Fine-Particle Inhaled Corticosteroids.

Postma DS, Dekhuijzen R, van der Molen T, Martin RJ, van Aalderen W, Roche N, Guilbert TW, Israel E, van Eickels D, Khalid JM, Herings RM, Overbeek JA, Miglio C, Thomas V, Hutton C, Hillyer EV, Price DB.

Allergy Asthma Immunol Res. 2017 Mar;9(2):116-125. doi: 10.4168/aair.2017.9.2.116.


[Prevalence of diabetes mellitus in the Netherlands more than doubled in the period 1999-2014].

Overbeek JA, van der Heijden AW, Herings RM, Nijpels G.

Ned Tijdschr Geneeskd. 2017;160:D673. Dutch.


Non-steroidal anti-inflammatory drugs and risk of heart failure in four European countries: nested case-control study.

Arfè A, Scotti L, Varas-Lorenzo C, Nicotra F, Zambon A, Kollhorst B, Schink T, Garbe E, Herings R, Straatman H, Schade R, Villa M, Lucchi S, Valkhoff V, Romio S, Thiessard F, Schuemie M, Pariente A, Sturkenboom M, Corrao G; Safety of Non-steroidal Anti-inflammatory Drugs (SOS) Project Consortium.

BMJ. 2016 Sep 28;354:i4857. doi: 10.1136/bmj.i4857.


Characterization and cholesterol management in patients with cardiovascular events and/or type 2 diabetes in the Netherlands.

Heintjes E, Kuiper J, Lucius B, Penning-van Beest F, Kutikova L, Liem A, Herings R.

Curr Med Res Opin. 2017 Jan;33(1):91-100. Epub 2016 Sep 29.


Rates of prostate surgery and acute urinary retention for benign prostatic hyperplasia in men treated with dutasteride or finasteride.

Kuiper JG, Bezemer ID, Driessen MT, Vasylyev A, Roehrborn CG, Penning-van Beest FJ, Herings RM.

BMC Urol. 2016 Aug 31;16(1):53. doi: 10.1186/s12894-016-0170-6.


Identifying Cases of Type 2 Diabetes in Heterogeneous Data Sources: Strategy from the EMIF Project.

Roberto G, Leal I, Sattar N, Loomis AK, Avillach P, Egger P, van Wijngaarden R, Ansell D, Reisberg S, Tammesoo ML, Alavere H, Pasqua A, Pedersen L, Cunningham J, Tramontan L, Mayer MA, Herings R, Coloma P, Lapi F, Sturkenboom M, van der Lei J, Schuemie MJ, Rijnbeek P, Gini R.

PLoS One. 2016 Aug 31;11(8):e0160648. doi: 10.1371/journal.pone.0160648. eCollection 2016.


Erratum to: Effectiveness of initiating extrafine-particle versus fine-particle inhaled corticosteroids as asthma therapy in the Netherlands.

van der Molen T, Postma DS, Martin RJ, Herings RM, Overbeek JA, Thomas V, Miglio C, Dekhuijzen R, Roche N, Guilbert T, Israel E, van Aalderen W, Hillyer EV, van Rysewyk S, Price DB.

BMC Pulm Med. 2016 Jul 23;16(1):105. doi: 10.1186/s12890-016-0270-9. No abstract available.


Post authorization safety study comparing quetiapine to risperidone and olanzapine.

Heintjes EM, Overbeek JA, Penning-van Beest FJ, Brobert G, Herings RM.

Hum Psychopharmacol. 2016 Jul;31(4):304-12. doi: 10.1002/hup.2539. Epub 2016 Jun 13.


Increased overall drug utilization in patients with psoriasis: a case-control study based on Dutch general practitioner data.

Dowlatshahi EA, Hollestein LM, Herings RM, Nijsten T, Wakkee M.

Br J Dermatol. 2017 Mar;176(3):634-642. doi: 10.1111/bjd.14754. Epub 2016 Oct 12.


Effectiveness of initiating extrafine-particle versus fine-particle inhaled corticosteroids as asthma therapy in the Netherlands.

van der Molen T, Postma DS, Martin RJ, Herings RM, Overbeek JA, Thomas V, Miglio C, Dekhuijzen R, Roche N, Guilbert T, Israel E, van Aalderen W, Hillyer EV, van Rysewyk S, Price DB.

BMC Pulm Med. 2016 May 17;16(1):80. doi: 10.1186/s12890-016-0234-0. Erratum in: BMC Pulm Med. 2016;16(1):105.


Impact of cancer diagnosis and treatment on glycaemic control among individuals with colorectal cancer using glucose-lowering drugs.

Zanders MM, van Herk-Sukel MP, Herings RM, van de Poll-Franse LV, Haak HR.

Acta Diabetol. 2016 Oct;53(5):727-35. doi: 10.1007/s00592-016-0863-z. Epub 2016 Apr 18.


Prescribing pattern of antipsychotic drugs during the years 1996-2010: a population-based database study in Europe with a focus on torsadogenic drugs.

Oteri A, Mazzaglia G, Pecchioli S, Molokhia M, Ulrichsen SP, Pedersen L, Poluzzi E, De Ponti F, Garbe E, Schink T, Herings R, Bezemer ID, Sturkenboom MC, Trifirò G.

Br J Clin Pharmacol. 2016 Aug;82(2):487-97. doi: 10.1111/bcp.12955. Epub 2016 May 18. Erratum in: Br J Clin Pharmacol. 2017 Jun;83(6):1360.


Risk of cardiac valvulopathy with use of bisphosphonates: a population-based, multi-country case-control study.

Coloma PM, de Ridder M, Bezemer I, Herings RM, Gini R, Pecchioli S, Scotti L, Rijnbeek P, Mosseveld M, van der Lei J, Trifirò G, Sturkenboom M; EU-ADR Consortium.

Osteoporos Int. 2016 May;27(5):1857-67. doi: 10.1007/s00198-015-3441-2. Epub 2015 Dec 22.


Use of oral contraceptives in three European countries: a population-based multi-database study.

Bezemer ID, Verhamme KM, Gini R, Mosseveld M, Rijnbeek PR, Trifirò G, Sturkenboom MC, Penning-van Beest FJ, Herings RM.

Eur J Contracept Reprod Health Care. 2016;21(1):81-7. doi: 10.3109/13625187.2015.1102220. Epub 2015 Oct 22.


Useful Interplay Between Spontaneous ADR Reports and Electronic Healthcare Records in Signal Detection.

Pacurariu AC, Straus SM, Trifirò G, Schuemie MJ, Gini R, Herings R, Mazzaglia G, Picelli G, Scotti L, Pedersen L, Arlett P, van der Lei J, Sturkenboom MC, Coloma PM.

Drug Saf. 2015 Dec;38(12):1201-10. doi: 10.1007/s40264-015-0341-5.


Are metformin, statin and aspirin use still associated with overall mortality among colorectal cancer patients with diabetes if adjusted for one another?

Zanders MM, van Herk-Sukel MP, Vissers PA, Herings RM, Haak HR, van de Poll-Franse LV.

Br J Cancer. 2015 Jul 28;113(3):403-10. doi: 10.1038/bjc.2015.259. Epub 2015 Jul 16.


Infants born before 32 weeks of gestation or with respiratory disease are most likely to receive palivizumab in the Netherlands.

Kool-Houweling LM, Penning-van Beest FJ, Bezemer ID, van Lingen RA, Herings RM.

Acta Paediatr. 2015 Sep;104(9):927-32. doi: 10.1111/apa.13081. Epub 2015 Jul 23.


The role of electronic healthcare record databases in paediatric drug safety surveillance: a retrospective cohort study.

de Bie S, Coloma PM, Ferrajolo C, Verhamme KM, Trifirò G, Schuemie MJ, Straus SM, Gini R, Herings R, Mazzaglia G, Picelli G, Ghirardi A, Pedersen L, Stricker BH, van der Lei J, Sturkenboom MC; EU-ADR consortium.

Br J Clin Pharmacol. 2015 Aug;80(2):304-14. doi: 10.1111/bcp.12610. Epub 2015 May 20.


Long term trends in oral antidiabetic drug use among children and adolescents in the Netherlands.

Fazeli Farsani S, Souverein PC, Overbeek JA, van der Vorst MM, Knibbe CA, Herings RM, de Boer A, Mantel-Teeuwisse AK.

Br J Clin Pharmacol. 2015 Aug;80(2):294-303. doi: 10.1111/bcp.12608. Epub 2015 May 20.


Quick assessment of drug-related admissions over time (QUADRAT study).

Warlé-van Herwaarden MF, Valkhoff VE, Herings RM, Engelkes M, van Blijderveen JC, Rodenburg EM, de Bie S, Alsma J, van de Steeg-Gompel C, Kramers C, Meyboom RH, Sturkenboom MC, De Smet PA.

Pharmacoepidemiol Drug Saf. 2015 May;24(5):495-503. doi: 10.1002/pds.3747. Epub 2015 Feb 12.


Evaluating performance of electronic healthcare records and spontaneous reporting data in drug safety signal detection.

Patadia VK, Schuemie MJ, Coloma P, Herings R, van der Lei J, Straus S, Sturkenboom M, Trifirò G.

Int J Clin Pharm. 2015 Feb;37(1):94-104. doi: 10.1007/s11096-014-0044-5. Epub 2014 Dec 9.


Using real-world healthcare data for pharmacovigilance signal detection - the experience of the EU-ADR project.

Patadia VK, Coloma P, Schuemie MJ, Herings R, Gini R, Mazzaglia G, Picelli G, Fornari C, Pedersen L, van der Lei J, Sturkenboom M, Trifirò G; EU-ADR consortium.

Expert Rev Clin Pharmacol. 2015 Jan;8(1):95-102. doi: 10.1586/17512433.2015.992878. Review.


Isotretinoin exposure during pregnancy: a population-based study in The Netherlands.

Zomerdijk IM, Ruiter R, Houweling LM, Herings RM, Sturkenboom MC, Straus SM, Stricker BH.

BMJ Open. 2014 Nov 12;4(11):e005602. doi: 10.1136/bmjopen-2014-005602.


Increasing trends in the incidence and prevalence rates of type 1 diabetes among children and adolescents in the Netherlands.

Fazeli Farsani S, Souverein PC, van der Vorst MM, Knibbe CA, Herings RM, de Boer A, Mantel-Teeuwisse AK.

Pediatr Diabetes. 2016 Feb;17(1):44-52. doi: 10.1111/pedi.12232. Epub 2014 Nov 7.


Incidence and Prevalence of COPD By Gold 2013 Classification in the Netherlands.

Van den Berg EJ, Overbeek JA, Penning-van Beest FJ, Khalid JM, Dekhuijzen PN, Herings R.

Value Health. 2014 Nov;17(7):A590. doi: 10.1016/j.jval.2014.08.2020. Epub 2014 Oct 26. No abstract available.


Development Of A Collaborative European Pharmacoepidemiologic Post-Authorization Safety Study (Pass) Programme Examining Rivaroxaban Use In Routine Clinical Practice.

Brobert G, García RL, Garbe E, Bezemer ID, Layton D, Friberg L, Suzart-Woischnik K, Alderson J, Winchester C, Herings RM, Jobski K, Schink T, Shakir S, Soriano-Gabarró M, Wallander MA.

Value Health. 2014 Nov;17(7):A473-4. doi: 10.1016/j.jval.2014.08.1350. Epub 2014 Oct 26. No abstract available.


Trend in Prevalence and Distribution of Diabetes Mellitus Type I and Type II in the Netherlands.

Overbeek JA, Penning FJ, van Dongen E, Herings RM.

Value Health. 2014 Nov;17(7):A337. doi: 10.1016/j.jval.2014.08.652. Epub 2014 Oct 26. No abstract available.

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