Sort by
Items per page

Send to

Choose Destination

Search results

Items: 18


Characterization of guided entry of tail-anchored proteins 3 homologues in Mycobacterium tuberculosis.

Hu K, Jordan AT, Zhang S, Dhabaria A, Kovach A, Rangel M, Ueberheide B, Li H, Darwin KH.

J Bacteriol. 2019 Apr 29. pii: JB.00159-19. doi: 10.1128/JB.00159-19. [Epub ahead of print]


The Mycobacterium tuberculosis Pup-proteasome system regulates nitrate metabolism through an essential protein quality control pathway.

Becker SH, Jastrab JB, Dhabaria A, Chaton CT, Rush JS, Korotkov KV, Ueberheide B, Darwin KH.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3202-3210. doi: 10.1073/pnas.1819468116. Epub 2019 Feb 5.


Cytokinin Signaling in Mycobacterium tuberculosis.

Samanovic MI, Hsu HC, Jones MB, Jones V, McNeil MR, Becker SH, Jordan AT, Strnad M, Xu C, Jackson M, Li H, Darwin KH.

MBio. 2018 Jun 19;9(3). pii: e00989-18. doi: 10.1128/mBio.00989-18.


Proteasome substrate capture and gate opening by the accessory factor PafE from Mycobacterium tuberculosis.

Hu K, Jastrab JB, Zhang S, Kovach A, Zhao G, Darwin KH, Li H.

J Biol Chem. 2018 Mar 30;293(13):4713-4723. doi: 10.1074/jbc.RA117.001471. Epub 2018 Feb 5.


Mycobacterium tuberculosis Proteasome Accessory Factor A (PafA) Can Transfer Prokaryotic Ubiquitin-Like Protein (Pup) between Substrates.

Zhang S, Burns-Huang KE, Janssen GV, Li H, Ovaa H, Hedstrom L, Darwin KH.

MBio. 2017 Feb 21;8(1). pii: e00122-17. doi: 10.1128/mBio.00122-17.


Structural Analysis of Mycobacterium tuberculosis Homologues of the Eukaryotic Proteasome Assembly Chaperone 2 (PAC2).

Bai L, Jastrab JB, Isasa M, Hu K, Yu H, Gygi SP, Darwin KH, Li H.

J Bacteriol. 2017 Apr 11;199(9). pii: e00846-16. doi: 10.1128/JB.00846-16. Print 2017 May 1.


Loss-of-Function Mutations in HspR Rescue the Growth Defect of a Mycobacterium tuberculosis Proteasome Accessory Factor E (pafE) Mutant.

Jastrab JB, Samanovic MI, Copin R, Shopsin B, Darwin KH.

J Bacteriol. 2017 Mar 14;199(7). pii: e00850-16. doi: 10.1128/JB.00850-16. Print 2017 Apr 1.


Bacterial Proteasomes: Mechanistic and Functional Insights.

Becker SH, Darwin KH.

Microbiol Mol Biol Rev. 2016 Dec 14;81(1). pii: e00036-16. Print 2017 Mar. Review.


Structural analysis of the dodecameric proteasome activator PafE in Mycobacterium tuberculosis.

Bai L, Hu K, Wang T, Jastrab JB, Darwin KH, Li H.

Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E1983-92. doi: 10.1073/pnas.1512094113. Epub 2016 Mar 21. Erratum in: Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):E2469.


Game of 'Somes: Protein Destruction for Mycobacterium tuberculosis Pathogenesis.

Samanovic MI, Darwin KH.

Trends Microbiol. 2016 Jan;24(1):26-34. doi: 10.1016/j.tim.2015.10.001. Epub 2015 Oct 29. Review.


Bacterial Proteasomes.

Jastrab JB, Darwin KH.

Annu Rev Microbiol. 2015;69:109-27. doi: 10.1146/annurev-micro-091014-104201. Review.


Mycobacterium tuberculosis and Copper: A Newly Appreciated Defense against an Old Foe?

Darwin KH.

J Biol Chem. 2015 Jul 31;290(31):18962-6. doi: 10.1074/jbc.R115.640193. Epub 2015 Jun 8. Review.


An adenosine triphosphate-independent proteasome activator contributes to the virulence of Mycobacterium tuberculosis.

Jastrab JB, Wang T, Murphy JP, Bai L, Hu K, Merkx R, Huang J, Chatterjee C, Ovaa H, Gygi SP, Li H, Darwin KH.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1763-72. doi: 10.1073/pnas.1423319112. Epub 2015 Mar 23.


Proteasomal control of cytokinin synthesis protects Mycobacterium tuberculosis against nitric oxide.

Samanovic MI, Tu S, Novák O, Iyer LM, McAllister FE, Aravind L, Gygi SP, Hubbard SR, Strnad M, Darwin KH.

Mol Cell. 2015 Mar 19;57(6):984-994. doi: 10.1016/j.molcel.2015.01.024. Epub 2015 Feb 26.


Copper homeostasis in Mycobacterium tuberculosis.

Shi X, Darwin KH.

Metallomics. 2015 Jun;7(6):929-34. doi: 10.1039/c4mt00305e. Review.


SAMPyling proteins in archaea.

Darwin KH, Hofmann K.

Trends Biochem Sci. 2010 Jun;35(6):348-51. doi: 10.1016/j.tibs.2010.03.003. Epub 2010 May 23. Review.


Prokaryotic ubiquitin-like protein (Pup), proteasomes and pathogenesis.

Darwin KH.

Nat Rev Microbiol. 2009 Jul;7(7):485-91. doi: 10.1038/nrmicro2148. Epub 2009 Jun 1. Review.


Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue.

Darwin KH, Lin G, Chen Z, Li H, Nathan CF.

Mol Microbiol. 2005 Jan;55(2):561-71.

Supplemental Content

Loading ...
Support Center