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Items: 1 to 50 of 124

1.

Correction: 14-3-3γ binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:Gαi-AlF4 - signaling complex and RGS14 nuclear localization.

Gerber KJ, Squires KE, Hepler JR.

J Biol Chem. 2019 Aug 9;294(32):12262. doi: 10.1074/jbc.AAC119.101131. No abstract available.

2.

Entomology in the 21st Century: Tackling Insect Invasions, Promoting Advancements in Technology, and Using Effective Science Communication-2018 Student Debates.

Parker C, Bernaola L, Lee BW, Elmquist D, Cohen A, Marshall A, Hepler J, Pekarcik A, Justus E, King K, Lee TY, Esquivel C, Hauri K, McCullough C, Hadden W, Ragozzino M, Roth M, Villegas J, Kraus E, Becker M, Mulcahy M, Chen R, Mittapelly P, Clem CS, Skinner R, Josek T, Pearlstein D, Tetlie J, Tran A, Auletta A, Benkert E, Tussey D.

J Insect Sci. 2019 Jul 1;19(4). pii: 4. doi: 10.1093/jisesa/iez069.

3.

Specific Proteomes of Hippocampal Regions CA2 and CA1 Reveal Proteins Linked to the Unique Physiology of Area CA2.

Gerber KJ, Dammer EB, Duong DM, Deng Q, Dudek SM, Seyfried NT, Hepler JR.

J Proteome Res. 2019 Jun 7;18(6):2571-2584. doi: 10.1021/acs.jproteome.9b00103. Epub 2019 May 14.

PMID:
31059263
4.

14-3-3γ binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:Gαi-AlF4- signaling complex and RGS14 nuclear localization.

Gerber KJ, Squires KE, Hepler JR.

J Biol Chem. 2018 Sep 21;293(38):14616-14631. doi: 10.1074/jbc.RA118.002816. Epub 2018 Aug 9. Erratum in: J Biol Chem. 2019 Aug 9;294(32):12262.

PMID:
30093406
5.

RGS14 Restricts Plasticity in Hippocampal CA2 by Limiting Postsynaptic Calcium Signaling.

Evans PR, Parra-Bueno P, Smirnov MS, Lustberg DJ, Dudek SM, Hepler JR, Yasuda R.

eNeuro. 2018 Jun 4;5(3). pii: ENEURO.0353-17.2018. doi: 10.1523/ENEURO.0353-17.2018. eCollection 2018 May-Jun.

6.

Genetic Analysis of Rare Human Variants of Regulators of G Protein Signaling Proteins and Their Role in Human Physiology and Disease.

Squires KE, Montañez-Miranda C, Pandya RR, Torres MP, Hepler JR.

Pharmacol Rev. 2018 Jul;70(3):446-474. doi: 10.1124/pr.117.015354. Review.

7.

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.

Evans PR, Gerber KJ, Dammer EB, Duong DM, Goswami D, Lustberg DJ, Zou J, Yang JJ, Dudek SM, Griffin PR, Seyfried NT, Hepler JR.

J Proteome Res. 2018 Apr 6;17(4):1700-1711. doi: 10.1021/acs.jproteome.8b00027. Epub 2018 Mar 20.

8.

Direct visualization of interaction between calmodulin and connexin45.

Zou J, Salarian M, Chen Y, Zhuo Y, Brown NE, Hepler JR, Yang JJ.

Biochem J. 2017 Nov 27;474(24):4035-4051. doi: 10.1042/BCJ20170426.

9.

Endogenous RGS14 is a cytoplasmic-nuclear shuttling protein that localizes to juxtanuclear membranes and chromatin-rich regions of the nucleus.

Branch MR, Hepler JR.

PLoS One. 2017 Sep 21;12(9):e0184497. doi: 10.1371/journal.pone.0184497. eCollection 2017.

10.

Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain.

Squires KE, Gerber KJ, Pare JF, Branch MR, Smith Y, Hepler JR.

Brain Struct Funct. 2018 Jan;223(1):233-253. doi: 10.1007/s00429-017-1487-y. Epub 2017 Aug 3.

11.

On Priming Action: Conclusions from a Meta-Analysis of the Behavioral Effects of Incidentally-Presented Words.

Weingarten E, Chen Q, McAdams M, Yi J, Hepler J, Albarracin D.

Curr Opin Psychol. 2016 Dec;12:53-57. Epub 2016 May 18.

12.

The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression.

Joy A, Kapoor M, Georges J, Butler L, Chang Y, Li C, Crouch A, Smirnov I, Nakada M, Hepler J, Marty M, Feuerstein BG.

J Neurooncol. 2016 Oct;130(1):43-52. Epub 2016 Jul 15.

13.

RGS14 regulates the lifetime of Gα-GTP signaling but does not prolong Gβγ signaling following receptor activation in live cells.

Brown NE, Lambert NA, Hepler JR.

Pharmacol Res Perspect. 2016 Aug 18;4(5):e00249. eCollection 2016 Oct.

14.

From primed concepts to action: A meta-analysis of the behavioral effects of incidentally presented words.

Weingarten E, Chen Q, McAdams M, Yi J, Hepler J, Albarracín D.

Psychol Bull. 2016 May;142(5):472-97. doi: 10.1037/bul0000030. Epub 2015 Dec 21.

15.

Roles for Regulator of G Protein Signaling Proteins in Synaptic Signaling and Plasticity.

Gerber KJ, Squires KE, Hepler JR.

Mol Pharmacol. 2016 Feb;89(2):273-86. doi: 10.1124/mol.115.102210. Epub 2015 Dec 11. Review.

16.

Appealing to fear: A meta-analysis of fear appeal effectiveness and theories.

Tannenbaum MB, Hepler J, Zimmerman RS, Saul L, Jacobs S, Wilson K, Albarracín D.

Psychol Bull. 2015 Nov;141(6):1178-204. doi: 10.1037/a0039729. Review.

17.

Regulator of G Protein Signaling 14: A Molecular Brake on Synaptic Plasticity Linked to Learning and Memory.

Evans PR, Dudek SM, Hepler JR.

Prog Mol Biol Transl Sci. 2015;133:169-206. doi: 10.1016/bs.pmbts.2015.03.006. Epub 2015 Apr 27. Review.

PMID:
26123307
18.

Bioluminescence resonance energy transfer to detect protein-protein interactions in live cells.

Brown NE, Blumer JB, Hepler JR.

Methods Mol Biol. 2015;1278:457-65. doi: 10.1007/978-1-4939-2425-7_30.

19.

Integration of G protein α (Gα) signaling by the regulator of G protein signaling 14 (RGS14).

Brown NE, Goswami D, Branch MR, Ramineni S, Ortlund EA, Griffin PR, Hepler JR.

J Biol Chem. 2015 Apr 3;290(14):9037-49. doi: 10.1074/jbc.M114.634329. Epub 2015 Feb 9.

20.

G protein coupled receptor signaling complexes in live cells.

Hepler JR.

Cell Logist. 2014 Jun 4;4:e29392. eCollection 2014.

21.

Liking More Means Doing More: Dispositional Attitudes Predict Patterns of General Action.

Hepler J, Albarracin D.

Soc Psychol (Gott). 2014 May;45(5):391-398. doi: 10.1027/1864-9335/a000198. Epub 2014 Jan 1.

22.

Regulator of G protein signaling 2 (RGS2) and RGS4 form distinct G protein-dependent complexes with protease activated-receptor 1 (PAR1) in live cells.

Ghil S, McCoy KL, Hepler JR.

PLoS One. 2014 Apr 17;9(4):e95355. doi: 10.1371/journal.pone.0095355. eCollection 2014.

23.

Neuroticism and attitudes toward action in 19 countries.

Ireland ME, Hepler J, Li H, Albarracín D.

J Pers. 2015 Jun;83(3):243-50. doi: 10.1111/jopy.12099. Epub 2014 Jun 5.

24.

Timescale halo: average-speed targets elicit more positive and less negative attributions than slow or fast targets.

Hernandez I, Preston JL, Hepler J.

PLoS One. 2014 Jan 8;9(1):e83320. doi: 10.1371/journal.pone.0083320. eCollection 2014.

25.

Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain.

Evans PR, Lee SE, Smith Y, Hepler JR.

J Comp Neurol. 2014 Jan 1;522(1):186-203. doi: 10.1002/cne.23395.

26.

Being Active and Impulsive: The Role of Goals for Action and Inaction in Self-Control.

Hepler J, Albarracin D, McCulloch KC, Noguchi K.

Motiv Emot. 2012 Dec 1;36(4):416-424.

27.

Complete unconscious control: using (in)action primes to demonstrate completely unconscious activation of inhibitory control mechanisms.

Hepler J, Albarracin D.

Cognition. 2013 Sep;128(3):271-9. doi: 10.1016/j.cognition.2013.04.012. Epub 2013 Jun 4.

28.
29.

Attitudes without objects: evidence for a dispositional attitude, its measurement, and its consequences.

Hepler J, Albarracín D.

J Pers Soc Psychol. 2013 Jun;104(6):1060-76. doi: 10.1037/a0032282. Epub 2013 Apr 15.

30.

Neuroscience and the soul: competing explanations for the human experience.

Preston JL, Ritter RS, Hepler J.

Cognition. 2013 Apr;127(1):31-7. doi: 10.1016/j.cognition.2012.12.003. Epub 2013 Jan 12.

PMID:
23318352
31.

The Ras-binding domain region of RGS14 regulates its functional interactions with heterotrimeric G proteins.

Zhao P, Nunn C, Ramineni S, Hepler JR, Chidiac P.

J Cell Biochem. 2013 Jun;114(6):1414-23. doi: 10.1002/jcb.24483.

32.

Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by Gαi1 and Gαi-linked G protein-coupled receptors.

Vellano CP, Brown NE, Blumer JB, Hepler JR.

J Biol Chem. 2013 Feb 1;288(5):3620-31. doi: 10.1074/jbc.M112.440057. Epub 2012 Dec 17.

33.

Protease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loop.

McCoy KL, Gyoneva S, Vellano CP, Smrcka AV, Traynelis SF, Hepler JR.

Cell Signal. 2012 Jun;24(6):1351-60. doi: 10.1016/j.cellsig.2012.01.011. Epub 2012 Jan 28.

34.

RGS14 at the interface of hippocampal signaling and synaptic plasticity.

Vellano CP, Lee SE, Dudek SM, Hepler JR.

Trends Pharmacol Sci. 2011 Nov;32(11):666-74. doi: 10.1016/j.tips.2011.07.005. Epub 2011 Sep 8. Review.

35.

G protein-coupled receptors and resistance to inhibitors of cholinesterase-8A (Ric-8A) both regulate the regulator of g protein signaling 14 RGS14·Gαi1 complex in live cells.

Vellano CP, Maher EM, Hepler JR, Blumer JB.

J Biol Chem. 2011 Nov 4;286(44):38659-69. doi: 10.1074/jbc.M111.274928. Epub 2011 Aug 31.

36.

General Action and Inaction Goals: Their Behavioral, Cognitive, and Affective Origins and Influences.

Albarracin D, Hepler J, Tannenbaum M.

Curr Dir Psychol Sci. 2011 Apr 1;20(2):119-123.

37.

Activation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8A.

Vellano CP, Shu FJ, Ramineni S, Yates CK, Tall GG, Hepler JR.

Biochemistry. 2011 Feb 8;50(5):752-62. doi: 10.1021/bi101910n. Epub 2011 Jan 11.

38.

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory.

Lee SE, Simons SB, Heldt SA, Zhao M, Schroeder JP, Vellano CP, Cowan DP, Ramineni S, Yates CK, Feng Y, Smith Y, Sweatt JD, Weinshenker D, Ressler KJ, Dudek SM, Hepler JR.

Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16994-8. doi: 10.1073/pnas.1005362107. Epub 2010 Sep 13.

39.

Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity.

Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E.

Sci Signal. 2010 May 11;3(121):ra37. doi: 10.1126/scisignal.2000647.

40.

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology.

McCoy KL, Traynelis SF, Hepler JR.

Mol Pharmacol. 2010 Jun;77(6):1005-15. doi: 10.1124/mol.109.062018. Epub 2010 Mar 9.

41.

RGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathways.

Shu FJ, Ramineni S, Hepler JR.

Cell Signal. 2010 Mar;22(3):366-76. doi: 10.1016/j.cellsig.2009.10.005.

42.

The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors.

Yuan H, Vance KM, Junge CE, Geballe MT, Snyder JP, Hepler JR, Yepes M, Low CM, Traynelis SF.

J Biol Chem. 2009 May 8;284(19):12862-73. doi: 10.1074/jbc.M805123200. Epub 2009 Feb 24.

43.

Regulators of G protein signaling proteins as central components of G protein-coupled receptor signaling complexes.

McCoy KL, Hepler JR.

Prog Mol Biol Transl Sci. 2009;86:49-74. doi: 10.1016/S1877-1173(09)86003-1. Epub 2009 Oct 7. Review.

PMID:
20374713
44.

Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1.

Mannaioni G, Orr AG, Hamill CE, Yuan H, Pedone KH, McCoy KL, Berlinguer Palmini R, Junge CE, Lee CJ, Yepes M, Hepler JR, Traynelis SF.

J Biol Chem. 2008 Jul 18;283(29):20600-11. doi: 10.1074/jbc.M803015200. Epub 2008 May 12.

45.

Unique hydrophobic extension of the RGS2 amphipathic helix domain imparts increased plasma membrane binding and function relative to other RGS R4/B subfamily members.

Gu S, He J, Ho WT, Ramineni S, Thal DM, Natesh R, Tesmer JJ, Hepler JR, Heximer SP.

J Biol Chem. 2007 Nov 9;282(45):33064-75. Epub 2007 Sep 11.

47.

RGSZ1 interacts with protein kinase C interacting protein PKCI-1 and modulates mu opioid receptor signaling.

Ajit SK, Ramineni S, Edris W, Hunt RA, Hum WT, Hepler JR, Young KH.

Cell Signal. 2007 Apr;19(4):723-30. Epub 2006 Oct 7.

PMID:
17126529
48.

Selective interactions between Gi alpha1 and Gi alpha3 and the GoLoco/GPR domain of RGS14 influence its dynamic subcellular localization.

Shu FJ, Ramineni S, Amyot W, Hepler JR.

Cell Signal. 2007 Jan;19(1):163-76. Epub 2006 Jul 25.

PMID:
16870394
49.

Cellular mechanisms that determine selective RGS protein regulation of G protein-coupled receptor signaling.

Neitzel KL, Hepler JR.

Semin Cell Dev Biol. 2006 Jun;17(3):383-9. Epub 2006 Mar 16. Review.

PMID:
16647283
50.

Cell signalling diversity of the Gqalpha family of heterotrimeric G proteins.

Hubbard KB, Hepler JR.

Cell Signal. 2006 Feb;18(2):135-50. Epub 2005 Sep 22. Review.

PMID:
16182515

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