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Highly coupled transport can be achieved in free-exchange transport models.

Hussey GA, Thomas NE, Henzler-Wildman KA.

J Gen Physiol. 2020 Jan 6;152(1). pii: e201912437. doi: 10.1085/jgp.201912437.


NMR Structural Analysis of Isolated Shaker Voltage-Sensing Domain in LPPG Micelles.

Chen H, Pan J, Gandhi DM, Dockendorff C, Cui Q, Chanda B, Henzler-Wildman KA.

Biophys J. 2019 Jul 23;117(2):388-398. doi: 10.1016/j.bpj.2019.06.020. Epub 2019 Jun 26.


Identification of an Alternating-Access Dynamics Mutant of EmrE with Impaired Transport.

Wu C, Wynne SA, Thomas NE, Uhlemann EM, Tate CG, Henzler-Wildman KA.

J Mol Biol. 2019 Jul 12;431(15):2777-2789. doi: 10.1016/j.jmb.2019.05.035. Epub 2019 May 31.


The C terminus of the bacterial multidrug transporter EmrE couples drug binding to proton release.

Thomas NE, Wu C, Morrison EA, Robinson AE, Werner JP, Henzler-Wildman KA.

J Biol Chem. 2018 Dec 7;293(49):19137-19147. doi: 10.1074/jbc.RA118.005430. Epub 2018 Oct 4.


A mass spectrometry based transport assay for studying EmrE transport of unlabeled substrates.

Robinson AE, Henderson JP, Henzler-Wildman KA.

Anal Biochem. 2018 May 15;549:130-135. doi: 10.1016/j.ab.2018.03.017. Epub 2018 Mar 17.


New free-exchange model of EmrE transport.

Robinson AE, Thomas NE, Morrison EA, Balthazor BM, Henzler-Wildman KA.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):E10083-E10091. doi: 10.1073/pnas.1708671114. Epub 2017 Nov 7.


Integrative NMR for biomolecular research.

Lee W, Cornilescu G, Dashti H, Eghbalnia HR, Tonelli M, Westler WM, Butcher SE, Henzler-Wildman KA, Markley JL.

J Biomol NMR. 2016 Apr;64(4):307-32. doi: 10.1007/s10858-016-0029-x. Epub 2016 Mar 29.


Role of protein dynamics in ion selectivity and allosteric coupling in the NaK channel.

Brettmann JB, Urusova D, Tonelli M, Silva JR, Henzler-Wildman KA.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15366-71. doi: 10.1073/pnas.1515965112. Epub 2015 Nov 30.


Asymmetric protonation of EmrE.

Morrison EA, Robinson AE, Liu Y, Henzler-Wildman KA.

J Gen Physiol. 2015 Dec;146(6):445-61. doi: 10.1085/jgp.201511404. Epub 2015 Nov 16.


Blocking dynamics of the SMR transporter EmrE impairs efflux activity.

Dutta S, Morrison EA, Henzler-Wildman KA.

Biophys J. 2014 Aug 5;107(3):613-620. doi: 10.1016/j.bpj.2014.06.030.


EmrE dimerization depends on membrane environment.

Dutta S, Morrison EA, Henzler-Wildman KA.

Biochim Biophys Acta. 2014 Jul;1838(7):1817-22. doi: 10.1016/j.bbamem.2014.03.013. Epub 2014 Mar 26.


Transported substrate determines exchange rate in the multidrug resistance transporter EmrE.

Morrison EA, Henzler-Wildman KA.

J Biol Chem. 2014 Mar 7;289(10):6825-36. doi: 10.1074/jbc.M113.535328. Epub 2014 Jan 21.


Red blood cell invasion by Plasmodium vivax: structural basis for DBP engagement of DARC.

Batchelor JD, Malpede BM, Omattage NS, DeKoster GT, Henzler-Wildman KA, Tolia NH.

PLoS Pathog. 2014 Jan;10(1):e1003869. doi: 10.1371/journal.ppat.1003869. Epub 2014 Jan 9.


Stereospecific binding of a disordered peptide segment mediates BK channel inactivation.

Gonzalez-Perez V, Zeng XH, Henzler-Wildman K, Lingle CJ.

Nature. 2012 May 3;485(7396):133-6. doi: 10.1038/nature10994. Erratum in: Nature. 2012 Sep 27;489(7417):590.


Reconstitution of integral membrane proteins into isotropic bicelles with improved sample stability and expanded lipid composition profile.

Morrison EA, Henzler-Wildman KA.

Biochim Biophys Acta. 2012 Mar;1818(3):814-20. doi: 10.1016/j.bbamem.2011.12.020. Epub 2011 Dec 29.


Antiparallel EmrE exports drugs by exchanging between asymmetric structures.

Morrison EA, DeKoster GT, Dutta S, Vafabakhsh R, Clarkson MW, Bahl A, Kern D, Ha T, Henzler-Wildman KA.

Nature. 2011 Dec 18;481(7379):45-50. doi: 10.1038/nature10703.


Analyzing conformational changes in the transport cycle of EmrE.

Henzler-Wildman K.

Curr Opin Struct Biol. 2012 Feb;22(1):38-43. doi: 10.1016/ Epub 2011 Nov 16. Review.


Nitrogen-14 solid-state NMR spectroscopy of aligned phospholipid bilayers to probe peptide-lipid interaction and oligomerization of membrane associated peptides.

Ramamoorthy A, Lee DK, Santos JS, Henzler-Wildman KA.

J Am Chem Soc. 2008 Aug 20;130(33):11023-9. doi: 10.1021/ja802210u. Epub 2008 Jul 23.


NMR structure of the cathelicidin-derived human antimicrobial peptide LL-37 in dodecylphosphocholine micelles.

Porcelli F, Verardi R, Shi L, Henzler-Wildman KA, Ramamoorthy A, Veglia G.

Biochemistry. 2008 May 20;47(20):5565-72. doi: 10.1021/bi702036s. Epub 2008 Apr 26.


Dynamic personalities of proteins.

Henzler-Wildman K, Kern D.

Nature. 2007 Dec 13;450(7172):964-72. Review.


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