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Items: 47

1.

Angiogenic potential of human mesenchymal stromal cell and circulating mononuclear cell cocultures is reflected in the expression profiles of proangiogenic factors leading to endothelial cell and pericyte differentiation.

Joensuu K, Uusitalo-Kylmälä L, Hentunen TA, Heino TJ.

J Tissue Eng Regen Med. 2018 Mar;12(3):775-783. doi: 10.1002/term.2496. Epub 2017 Sep 25.

PMID:
28593699
2.

Enhanced osteoblastic differentiation and bone formation in co-culture of human bone marrow mesenchymal stromal cells and peripheral blood mononuclear cells with exogenous VEGF.

Joensuu K, Uusitalo L, Alm JJ, Aro HT, Hentunen TA, Heino TJ.

Orthop Traumatol Surg Res. 2015 May;101(3):381-6. doi: 10.1016/j.otsr.2015.01.014. Epub 2015 Mar 23.

3.

Characterization of bone mineral-resembling biomaterials for optimizing human osteoclast differentiation and resorption.

Nakamura M, Hentunen T, Salonen J, Nagai A, Yamashita K.

J Biomed Mater Res A. 2013 Nov;101(11):3141-51. doi: 10.1002/jbm.a.34621. Epub 2013 Mar 30.

PMID:
23554241
4.

Transient 100 nM dexamethasone treatment reduces inter- and intraindividual variations in osteoblastic differentiation of bone marrow-derived human mesenchymal stem cells.

Alm JJ, Heino TJ, Hentunen TA, Väänänen HK, Aro HT.

Tissue Eng Part C Methods. 2012 Sep;18(9):658-66. doi: 10.1089/ten.TEC.2011.0675. Epub 2012 May 14.

PMID:
22428545
5.

Do microRNAs regulate bone marrow stem cell niche physiology?

Laine SK, Hentunen T, Laitala-Leinonen T.

Gene. 2012 Apr 10;497(1):1-9. doi: 10.1016/j.gene.2012.01.045. Epub 2012 Jan 28. Review.

PMID:
22306262
6.

Interaction between marrow-derived human mesenchymal stem cells and peripheral blood mononuclear cells in endothelial cell differentiation.

Joensuu K, Paatero I, Alm JJ, Elenius K, Aro HT, Heino TJ, Hentunen TA.

Scand J Surg. 2011;100(3):216-22.

PMID:
22108752
7.

Osteoclasts in neurofibromatosis type 1 display enhanced resorption capacity, aberrant morphology, and resistance to serum deprivation.

Heervä E, Alanne MH, Peltonen S, Kuorilehto T, Hentunen T, Väänänen K, Peltonen J.

Bone. 2010 Sep;47(3):583-90. doi: 10.1016/j.bone.2010.06.001. Epub 2010 Jun 9.

PMID:
20541045
8.

Circulating plastic adherent mesenchymal stem cells in aged hip fracture patients.

Alm JJ, Koivu HM, Heino TJ, Hentunen TA, Laitinen S, Aro HT.

J Orthop Res. 2010 Dec;28(12):1634-42. doi: 10.1002/jor.21167.

9.

Surface electric fields increase osteoblast adhesion through improved wettability on hydroxyapatite electret.

Nakamura M, Nagai A, Hentunen T, Salonen J, Sekijima Y, Okura T, Hashimoto K, Toda Y, Monma H, Yamashita K.

ACS Appl Mater Interfaces. 2009 Oct;1(10):2181-9. doi: 10.1021/am900341v.

PMID:
20355852
10.

Microdamage detection and repair in bone: fracture mechanics, histology, cell biology.

Hazenberg JG, Hentunen TA, Heino TJ, Kurata K, Lee TC, Taylor D.

Technol Health Care. 2009;17(1):67-75. doi: 10.3233/THC-2009-0536.

PMID:
19478407
11.

Expression of macrophage inhibitory cytokine-1 in prostate cancer bone metastases induces osteoclast activation and weight loss.

Wakchoure S, Swain TM, Hentunen TA, Bauskin AR, Brown DA, Breit SN, Vuopala KS, Harris KW, Selander KS.

Prostate. 2009 May 1;69(6):652-61. doi: 10.1002/pros.20913.

PMID:
19152406
12.

Impact of stromal cell composition on BMP-induced chondrogenic differentiation of mouse bone marrow derived mesenchymal cells.

Taipaleenmäki H, Suomi S, Hentunen T, Laitala-Leinonen T, Säämänen AM.

Exp Cell Res. 2008 Aug 1;314(13):2400-10. doi: 10.1016/j.yexcr.2008.04.019. Epub 2008 May 15.

PMID:
18565511
13.

Differentiation of osteoblasts and osteocytes from mesenchymal stem cells.

Heino TJ, Hentunen TA.

Curr Stem Cell Res Ther. 2008 May;3(2):131-45. Review.

PMID:
18473879
14.

MicroRNAs regulate osteogenesis and chondrogenesis of mouse bone marrow stromal cells.

Suomi S, Taipaleenmäki H, Seppänen A, Ripatti T, Väänänen K, Hentunen T, Säämänen AM, Laitala-Leinonen T.

Gene Regul Syst Bio. 2008 Apr 22;2:177-91.

15.

Inhibition of cyclooxygenase-2 down-regulates osteoclast and osteoblast differentiation and favours adipocyte formation in vitro.

Kellinsalmi M, Parikka V, Risteli J, Hentunen T, Leskelä HV, Lehtonen S, Selander K, Väänänen K, Lehenkari P.

Eur J Pharmacol. 2007 Oct 31;572(2-3):102-10. Epub 2007 Jun 29.

PMID:
17632097
16.

Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro.

Michael H, Härkönen PL, Kangas L, Väänänen HK, Hentunen TA.

Br J Pharmacol. 2007 Jun;151(3):384-95. Epub 2007 Apr 10.

17.

The properties of biomimetically processed calcium phosphate on bioactive ceramics and their response on bone cells.

Vaahtio M, Peltola T, Hentunen T, Ylänen H, Areva S, Wolke J, Salonen JI.

J Mater Sci Mater Med. 2006 Nov;17(11):1113-25. Epub 2006 Nov 22.

PMID:
17122926
18.

Regulation of osteoblast differentiation: a novel function for fibroblast growth factor 8.

Valta MP, Hentunen T, Qu Q, Valve EM, Harjula A, Seppänen JA, Väänänen HK, Härkönen PL.

Endocrinology. 2006 May;147(5):2171-82. Epub 2006 Jan 26.

PMID:
16439448
19.

Estrogen and testosterone use different cellular pathways to inhibit osteoclastogenesis and bone resorption.

Michael H, Härkönen PL, Väänänen HK, Hentunen TA.

J Bone Miner Res. 2005 Dec;20(12):2224-32. Epub 2005 Aug 1.

20.

Isolated primary osteocytes express functional gap junctions in vitro.

Gu G, Nars M, Hentunen TA, Metsikkö K, Väänänen HK.

Cell Tissue Res. 2006 Feb;323(2):263-71. Epub 2005 Sep 21.

PMID:
16175387
21.

Death of osteocytes turns off the inhibition of osteoclasts and triggers local bone resorption.

Gu G, Mulari M, Peng Z, Hentunen TA, Väänänen HK.

Biochem Biophys Res Commun. 2005 Oct 7;335(4):1095-101.

PMID:
16111656
22.

Estrogen protects primary osteocytes against glucocorticoid-induced apoptosis.

Gu G, Hentunen TA, Nars M, Härkönen PL, Väänänen HK.

Apoptosis. 2005 May;10(3):583-95.

PMID:
15909120
23.

Estrogen responsiveness of bone formation in vitro and altered bone phenotype in aged estrogen receptor-alpha-deficient male and female mice.

Parikka V, Peng Z, Hentunen T, Risteli J, Elo T, Väänänen HK, Härkönen P.

Eur J Endocrinol. 2005 Feb;152(2):301-14.

PMID:
15745940
24.

Characterization of circulating human osteoclast progenitors: development of in vitro resorption assay.

Husheem M, Nyman JK, Vääräniemi J, Vaananen HK, Hentunen TA.

Calcif Tissue Int. 2005 Mar;76(3):222-30. Epub 2005 Feb 7.

PMID:
15692727
25.
26.

Release of intact and fragmented osteocalcin molecules from bone matrix during bone resorption in vitro.

Ivaska KK, Hentunen TA, Vääräniemi J, Ylipahkala H, Pettersson K, Väänänen HK.

J Biol Chem. 2004 Apr 30;279(18):18361-9. Epub 2004 Feb 16.

27.

Characterization of microrough bioactive glass surface: surface reactions and osteoblast responses in vitro.

Itälä A, Ylänen HO, Yrjans J, Heino T, Hentunen T, Hupa M, Aro HT.

J Biomed Mater Res. 2002 Dec 5;62(3):404-11.

PMID:
12209926
28.

Serum tartrate-resistant acid phosphatase isoforms in rheumatoid arthritis.

Janckila AJ, Neustadt DH, Nakasato YR, Halleen JM, Hentunen T, Yam LT.

Clin Chim Acta. 2002 Jun;320(1-2):49-58.

PMID:
11983200
29.

Osteocytes inhibit osteoclastic bone resorption through transforming growth factor-beta: enhancement by estrogen.

Heino TJ, Hentunen TA, Väänänen HK.

J Cell Biochem. 2002;85(1):185-97.

PMID:
11891862
30.

Carbonic anhydrases in calcified tissues.

Hentunen TA, Härkönen PL, Väänänen HK.

EXS. 2000;(90):491-7. Review. No abstract available.

PMID:
11268532
31.
32.

A murine model of inflammatory bone disease.

Hentunen TA, Choi SJ, Boyce BF, Dallas MR, Dallas SL, Shen-Ong GL, Roodman GD.

Bone. 2000 Feb;26(2):183-8.

PMID:
10678414
33.

Intracellular fragmentation of bone resorption products by reactive oxygen species generated by osteoclastic tartrate-resistant acid phosphatase.

Halleen JM, Räisänen S, Salo JJ, Reddy SV, Roodman GD, Hentunen TA, Lehenkari PP, Kaija H, Vihko P, Väänänen HK.

J Biol Chem. 1999 Aug 13;274(33):22907-10.

34.

Characterization of immortalized osteoclast precursors developed from mice transgenic for both bcl-X(L) and simian virus 40 large T antigen.

Hentunen TA, Jackson SH, Chung H, Reddy SV, Lorenzo J, Choi SJ, Roodman GD.

Endocrinology. 1999 Jul;140(7):2954-61.

PMID:
10385386
35.

Carbonic anhydrase II plays a major role in osteoclast differentiation and bone resorption by effecting the steady state intracellular pH and Ca2+.

Lehenkari P, Hentunen TA, Laitala-Leinonen T, Tuukkanen J, Väänänen HK.

Exp Cell Res. 1998 Jul 10;242(1):128-37.

PMID:
9665810
36.

Immortalization of osteoclast precursors by targeting Bcl -XL and Simian virus 40 large T antigen to the osteoclast lineage in transgenic mice.

Hentunen TA, Reddy SV, Boyce BF, Devlin R, Park HR, Chung H, Selander KS, Dallas M, Kurihara N, Galson DL, Goldring SR, Koop BA, Windle JJ, Roodman GD.

J Clin Invest. 1998 Jul 1;102(1):88-97.

37.

Characterization of serum tartrate-resistant acid phosphatase and development of a direct two-site immunoassay.

Halleen JM, Hentunen TA, Karp M, Käkönen SM, Pettersson K, Väänänen HK.

J Bone Miner Res. 1998 Apr;13(4):683-7.

38.

Tartrate-resistant acid phosphatase from human bone: purification and development of an immunoassay.

Halleen J, Hentunen TA, Hellman J, Väänänen HK.

J Bone Miner Res. 1996 Oct;11(10):1444-52.

PMID:
8889844
39.

Effects of recombinant human osteogenic protein-1 on the differentiation of osteoclast-like cells and bone resorption.

Hentunen TA, Lakkakorpi PT, Tuukkanen J, Lehenkari PP, Sampath TK, Väänänen HK.

Biochem Biophys Res Commun. 1995 Apr 17;209(2):433-43.

PMID:
7733910
40.

Structural relationship between DNA polymerases epsilon and epsilon* and their occurrence in eukaryotic cells.

Uitto L, Halleen J, Hentunen T, Höyhtyä M, Syväoja JE.

Nucleic Acids Res. 1995 Jan 25;23(2):244-7.

41.

Osteoclast recruiting activity in bone matrix.

Hentunen TA, Cunningham NS, Vuolteenaho O, Reddi AH, Väänänen HK.

Bone Miner. 1994 Jun;25(3):183-98.

PMID:
8086857
42.

Local expression and exocytosis of viral glycoproteins in multinucleated muscle cells.

Metsikkö K, Hentunen T, Väänänen K.

J Cell Biol. 1992 Jun;117(5):987-95.

43.

Inhibition of bone resorption by a monoclonal antibody that reacts with a 150 kD membrane protein in chicken osteoclasts.

Hentunen TA, Lakkakorpi PT, Rautiala T, Väänänen HK.

J Bone Miner Res. 1991 Oct;6(10):1091-7.

PMID:
1724590
44.

Evidence for the presence of a proton pump of the vacuolar H(+)-ATPase type in the ruffled borders of osteoclasts.

Väänänen HK, Karhukorpi EK, Sundquist K, Wallmark B, Roininen I, Hentunen T, Tuukkanen J, Lakkakorpi P.

J Cell Biol. 1990 Sep;111(3):1305-11.

45.

Osteoclasts and a small population of peripheral blood cells share common surface antigens.

Hentunen TA, Tuukkanen J, Väänänen HK.

Calcif Tissue Int. 1990 Jul;47(1):8-17.

PMID:
2196099
46.

Organization of osteoclast microfilaments during the attachment to bone surface in vitro.

Lakkakorpi P, Tuukkanen J, Hentunen T, Järvelin K, Väänänen K.

J Bone Miner Res. 1989 Dec;4(6):817-25.

PMID:
2692403
47.

Mechanism of osteoclast mediated bone resorption.

Väänänen HK, Hentunen T, Lakkakorpi P, Parvinen EK, Sundqvist K, Tuukkanen J.

Ann Chir Gynaecol. 1988;77(5-6):193-6. Review.

PMID:
3076045

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