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Items: 29

1.

Whole Exome Sequencing Reveals the Major Genetic Contributors to Non-Syndromic Tetralogy of Fallot.

Page DJ, Miossec MJ, Williams SG, Monaghan RM, Fotiou E, Cordell H, Sutcliffe L, Topf A, Bourgey M, Bourque G, Eveleigh R, Dunwoodie SL, Winlaw DS, Bhattacharya S, Breckpot J, Devriendt K, Gewillig M, Brook JD, Setchfield KJ, Bu'Lock F, o'sullivan JJ, Stuart G, Bezzina CR, Mulder BJ, Postma AV, Bentham JR, Baron M, Bhaskar SS, Black GC, Newman WG, Hentges KE, Lathrop GM, Santibanez Koref M, Keavney B.

Circ Res. 2018 Nov 28. doi: 10.1161/CIRCRESAHA.118.313250. [Epub ahead of print]

PMID:
30582441
2.

Identifying mouse developmental essential genes using machine learning.

Tian D, Wenlock S, Kabir M, Tzotzos G, Doig AJ, Hentges KE.

Dis Model Mech. 2018 Dec 13;11(12). pii: dmm034546. doi: 10.1242/dmm.034546.

3.

Non-muscle myosin IIB (Myh10) is required for epicardial function and coronary vessel formation during mammalian development.

Ridge LA, Mitchell K, Al-Anbaki A, Shaikh Qureshi WM, Stephen LA, Tenin G, Lu Y, Lupu IE, Clowes C, Robertson A, Barnes E, Wright JA, Keavney B, Ehler E, Lovell SC, Kadler KE, Hentges KE.

PLoS Genet. 2017 Oct 30;13(10):e1007068. doi: 10.1371/journal.pgen.1007068. eCollection 2017 Oct.

4.

Properties of genes essential for mouse development.

Kabir M, Barradas A, Tzotzos GT, Hentges KE, Doig AJ.

PLoS One. 2017 May 31;12(5):e0178273. doi: 10.1371/journal.pone.0178273. eCollection 2017.

5.

Transcriptional regulation of the proto-oncogene Zfp521 by SPI1 (PU.1) and HOXC13.

Yu M, Al-Dallal S, Al-Haj L, Panjwani S, McCartney AS, Edwards SM, Manjunath P, Walker C, Awgulewitsch A, Hentges KE.

Genesis. 2016 Oct;54(10):519-533. doi: 10.1002/dvg.22963. Epub 2016 Aug 29.

6.

Enforced Expression of Hoxa3 Inhibits Classical and Promotes Alternative Activation of Macrophages In Vitro and In Vivo.

Al Sadoun H, Burgess M, Hentges KE, Mace KA.

J Immunol. 2016 Aug 1;197(3):872-84. doi: 10.4049/jimmunol.1501944. Epub 2016 Jun 24.

7.

Zfp521 promotes B-cell viability and cyclin D1 gene expression in a B cell culture system.

Al Dallal S, Wolton K, Hentges KE.

Leuk Res. 2016 Jul;46:10-7. doi: 10.1016/j.leukres.2016.03.013. Epub 2016 Apr 9.

8.

Locus heterogeneity disease genes encode proteins with high interconnectivity in the human protein interaction network.

Keith BP, Robertson DL, Hentges KE.

Front Genet. 2014 Dec 9;5:434. doi: 10.3389/fgene.2014.00434. eCollection 2014.

9.

Erbb2 is required for cardiac atrial electrical activity during development.

Tenin G, Clowes C, Wolton K, Krejci E, Wright JA, Lovell SC, Sedmera D, Hentges KE.

PLoS One. 2014 Sep 30;9(9):e107041. doi: 10.1371/journal.pone.0107041. eCollection 2014.

10.

The functional diversity of essential genes required for mammalian cardiac development.

Clowes C, Boylan MG, Ridge LA, Barnes E, Wright JA, Hentges KE.

Genesis. 2014 Aug;52(8):713-37. doi: 10.1002/dvg.22794. Epub 2014 Jun 24. Review.

11.

Defining the role of essential genes in human disease.

Dickerson JE, Zhu A, Robertson DL, Hentges KE.

PLoS One. 2011;6(11):e27368. doi: 10.1371/journal.pone.0027368. Epub 2011 Nov 11.

12.

Mediator complex proteins are required for diverse developmental processes.

Hentges KE.

Semin Cell Dev Biol. 2011 Sep;22(7):769-75. doi: 10.1016/j.semcdb.2011.07.025. Epub 2011 Aug 10. Review.

PMID:
21854862
13.

The Mediator complex: crucial functions in transcription with links to development and disease.

Hentges KE.

Semin Cell Dev Biol. 2011 Sep;22(7):728. doi: 10.1016/j.semcdb.2011.08.002. Epub 2011 Aug 11. No abstract available.

PMID:
21854861
14.

Gene duplication and environmental adaptation within yeast populations.

Ames RM, Rash BM, Hentges KE, Robertson DL, Delneri D, Lovell SC.

Genome Biol Evol. 2010;2:591-601. doi: 10.1093/gbe/evq043. Epub 2010 Jul 21.

15.

Genome-wide identification of mouse congenital heart disease loci.

Kamp A, Peterson MA, Svenson KL, Bjork BC, Hentges KE, Rajapaksha TW, Moran J, Justice MJ, Seidman JG, Seidman CE, Moskowitz IP, Beier DR.

Hum Mol Genet. 2010 Aug 15;19(16):3105-13. doi: 10.1093/hmg/ddq211. Epub 2010 May 28.

16.

The Mediator complex protein Med31 is required for embryonic growth and cell proliferation during mammalian development.

Risley MD, Clowes C, Yu M, Mitchell K, Hentges KE.

Dev Biol. 2010 Jun 15;342(2):146-56. doi: 10.1016/j.ydbio.2010.03.019. Epub 2010 Mar 27.

17.

Discovery of candidate disease genes in ENU-induced mouse mutants by large-scale sequencing, including a splice-site mutation in nucleoredoxin.

Boles MK, Wilkinson BM, Wilming LG, Liu B, Probst FJ, Harrow J, Grafham D, Hentges KE, Woodward LP, Maxwell A, Mitchell K, Risley MD, Johnson R, Hirschi K, Lupski JR, Funato Y, Miki H, Marin-Garcia P, Matthews L, Coffey AJ, Parker A, Hubbard TJ, Rogers J, Bradley A, Adams DJ, Justice MJ.

PLoS Genet. 2009 Dec;5(12):e1000759. doi: 10.1371/journal.pgen.1000759. Epub 2009 Dec 11.

18.

Correlation of microsynteny conservation and disease gene distribution in mammalian genomes.

Lovell SC, Li X, Weerasinghe NR, Hentges KE.

BMC Genomics. 2009 Nov 12;10:521. doi: 10.1186/1471-2164-10-521.

19.

The use of scenario-based-learning interactive software to create custom virtual laboratory scenarios for teaching genetics.

Breakey KM, Levin D, Miller I, Hentges KE.

Genetics. 2008 Jul;179(3):1151-5. doi: 10.1534/genetics.108.090381. Epub 2008 Jun 18.

20.

Retroviral insertions in the VISION database identify molecular pathways in mouse lymphoid leukemia and lymphoma.

Weiser KC, Liu B, Hansen GM, Skapura D, Hentges KE, Yarlagadda S, Morse Iii HC, Justice MJ.

Mamm Genome. 2007 Oct;18(10):709-22. Epub 2007 Oct 10.

21.

Regional variation in the density of essential genes in mice.

Hentges KE, Pollock DD, Liu B, Justice MJ.

PLoS Genet. 2007 May 4;3(5):e72. Epub 2007 Mar 21.

22.

Novel lethal mouse mutants produced in balancer chromosome screens.

Hentges KE, Nakamura H, Furuta Y, Yu Y, Thompson DM, O'Brien W, Bradley A, Justice MJ.

Gene Expr Patterns. 2006 Aug;6(6):653-65. Epub 2006 Feb 8.

PMID:
16466971
23.

Evi3, a zinc-finger protein related to EBFAZ, regulates EBF activity in B-cell leukemia.

Hentges KE, Weiser KC, Schountz T, Woodward LS, Morse HC, Justice MJ.

Oncogene. 2005 Feb 10;24(7):1220-30.

PMID:
15580294
24.

Checks and balancers: balancer chromosomes to facilitate genome annotation.

Hentges KE, Justice MJ.

Trends Genet. 2004 Jun;20(6):252-9. Review. Erratum in: Trends Genet. 2005 Jan;21(1):36.

PMID:
15145578
25.

Comparative physical maps of the human and mouse Meckel syndrome critical regions.

Hentges KE, Kyttälä M, Justice MJ, Peltonen L.

Mamm Genome. 2004 Apr;15(4):252-64.

PMID:
15112103
26.

Functional genetic analysis of mouse chromosome 11.

Kile BT, Hentges KE, Clark AT, Nakamura H, Salinger AP, Liu B, Box N, Stockton DW, Johnson RL, Behringer RR, Bradley A, Justice MJ.

Nature. 2003 Sep 4;425(6953):81-6.

27.

Tnfrsf13c (Baffr) is mis-expressed in tumors with murine leukemia virus insertions at Lvis22.

Hentges KE, Yarlagadda SP, Justice MJ.

Genomics. 2002 Aug;80(2):204-12.

PMID:
12160734
28.

FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse.

Hentges KE, Sirry B, Gingeras AC, Sarbassov D, Sonenberg N, Sabatini D, Peterson AS.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13796-801. Epub 2001 Nov 13.

29.

Steroidogenic factor 1 and Dax-1 colocalize in multiple cell lineages: potential links in endocrine development.

Ikeda Y, Swain A, Weber TJ, Hentges KE, Zanaria E, Lalli E, Tamai KT, Sassone-Corsi P, Lovell-Badge R, Camerino G, Parker KL.

Mol Endocrinol. 1996 Oct;10(10):1261-72.

PMID:
9121493

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