Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 397


Single cell RNA sequencing identifies unique inflammatory airspace macrophage subsets.

Mould KJ, Jackson ND, Henson PM, Seibold M, Janssen WJ.

JCI Insight. 2019 Mar 7;4(5). pii: 126556. doi: 10.1172/jci.insight.126556. eCollection 2019 Mar 7.


Immune Surveillance by Natural IgM Is Required for Early Neoantigen Recognition and Initiation of Adaptive Immunity.

Atif SM, Gibbings SL, Redente EF, Camp FA, Torres RM, Kedl RM, Henson PM, Jakubzick CV.

Am J Respir Cell Mol Biol. 2018 Nov;59(5):580-591. doi: 10.1165/rcmb.2018-0159OC.


Flow Cytometry Underestimates and Planimetry Overestimates Alveolar Epithelial Type 2 Cell Expansion after Lung Injury.

Jansing NL, Patel N, McClendon J, Redente EF, Henson PM, Tuder RM, Hyde DM, Nyengaard JR, Zemans RL.

Am J Respir Crit Care Med. 2018 Aug 1;198(3):390-392. doi: 10.1164/rccm.201709-1838LE. No abstract available.


Phagocytosis of microparticles by alveolar macrophages during acute lung injury requires MerTK.

Mohning MP, Thomas SM, Barthel L, Mould KJ, McCubbrey AL, Frasch SC, Bratton DL, Henson PM, Janssen WJ.

Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L69-L82. doi: 10.1152/ajplung.00058.2017. Epub 2017 Sep 21.


Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice.

Neudecker V, Brodsky KS, Clambey ET, Schmidt EP, Packard TA, Davenport B, Standiford TJ, Weng T, Fletcher AA, Barthel L, Masterson JC, Furuta GT, Cai C, Blackburn MR, Ginde AA, Graner MW, Janssen WJ, Zemans RL, Evans CM, Burnham EL, Homann D, Moss M, Kreth S, Zacharowski K, Henson PM, Eltzschig HK.

Sci Transl Med. 2017 Sep 20;9(408). pii: eaah5360. doi: 10.1126/scitranslmed.aah5360.


Deletion of c-FLIP from CD11bhi Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis.

McCubbrey AL, Barthel L, Mohning MP, Redente EF, Mould KJ, Thomas SM, Leach SM, Danhorn T, Gibbings SL, Jakubzick CV, Henson PM, Janssen WJ.

Am J Respir Cell Mol Biol. 2018 Jan;58(1):66-78. doi: 10.1165/rcmb.2017-0154OC.


Cell Removal: Efferocytosis.

Henson PM.

Annu Rev Cell Dev Biol. 2017 Oct 6;33:127-144. doi: 10.1146/annurev-cellbio-111315-125315. Epub 2017 Jun 14. Review.


Unbiased Quantitation of Alveolar Type II to Alveolar Type I Cell Transdifferentiation during Repair after Lung Injury in Mice.

Jansing NL, McClendon J, Henson PM, Tuder RM, Hyde DM, Zemans RL.

Am J Respir Cell Mol Biol. 2017 Nov;57(5):519-526. doi: 10.1165/rcmb.2017-0037MA.


Monocyte differentiation and antigen-presenting functions.

Jakubzick CV, Randolph GJ, Henson PM.

Nat Rev Immunol. 2017 Jun;17(6):349-362. doi: 10.1038/nri.2017.28. Epub 2017 Apr 24. Review.


Three Unique Interstitial Macrophages in the Murine Lung at Steady State.

Gibbings SL, Thomas SM, Atif SM, McCubbrey AL, Desch AN, Danhorn T, Leach SM, Bratton DL, Henson PM, Janssen WJ, Jakubzick CV.

Am J Respir Cell Mol Biol. 2017 Jul;57(1):66-76. doi: 10.1165/rcmb.2016-0361OC.


Myeloid Cell Turnover and Clearance.

Janssen WJ, Bratton DL, Jakubzick CV, Henson PM.

Microbiol Spectr. 2016 Nov;4(6). doi: 10.1128/microbiolspec.MCHD-0005-2015. Review.


G2A Signaling Dampens Colitic Inflammation via Production of IFN-γ.

Frasch SC, McNamee EN, Kominsky D, Jedlicka P, Jakubzick C, Zemski Berry K, Mack M, Furuta GT, Lee JJ, Henson PM, Colgan SP, Bratton DL.

J Immunol. 2016 Aug 15;197(4):1425-34. doi: 10.4049/jimmunol.1600264. Epub 2016 Jul 8.


Ly6C(+) monocyte efferocytosis and cross-presentation of cell-associated antigens.

Larson SR, Atif SM, Gibbings SL, Thomas SM, Prabagar MG, Danhorn T, Leach SM, Henson PM, Jakubzick CV.

Cell Death Differ. 2016 Jun;23(6):997-1003. doi: 10.1038/cdd.2016.24. Epub 2016 Mar 18.


Flow Cytometric Analysis of Mononuclear Phagocytes in Nondiseased Human Lung and Lung-Draining Lymph Nodes.

Desch AN, Gibbings SL, Goyal R, Kolde R, Bednarek J, Bruno T, Slansky JE, Jacobelli J, Mason R, Ito Y, Messier E, Randolph GJ, Prabagar M, Atif SM, Segura E, Xavier RJ, Bratton DL, Janssen WJ, Henson PM, Jakubzick CV.

Am J Respir Crit Care Med. 2016 Mar 15;193(6):614-26. doi: 10.1164/rccm.201507-1376OC.


A Distinct Class of Antibodies May Be an Indicator of Gray Matter Autoimmunity in Early and Established Relapsing Remitting Multiple Sclerosis Patients.

Ligocki AJ, Rivas JR, Rounds WH, Guzman AA, Li M, Spadaro M, Lahey L, Chen D, Henson PM, Graves D, Greenberg BM, Frohman EM, Ward ES, Robinson W, Meinl E, White CL 3rd, Stowe AM, Monson NL.

ASN Neuro. 2015 Oct 21;7(5). pii: 1759091415609613. doi: 10.1177/1759091415609613. Print 2015 Sep-Oct.


Impaired efferocytosis in human chronic granulomatous disease is reversed by pioglitazone treatment.

Fernandez-Boyanapalli RF, Falcone EL, Zerbe CS, Marciano BE, Frasch SC, Henson PM, Holland SM, Bratton DL.

J Allergy Clin Immunol. 2015 Nov;136(5):1399-1401.e3. doi: 10.1016/j.jaci.2015.07.034. Epub 2015 Sep 18. No abstract available.


Mammary epithelial cell phagocytosis downstream of TGF-β3 is characterized by adherens junction reorganization.

Fornetti J, Flanders KC, Henson PM, Tan AC, Borges VF, Schedin P.

Cell Death Differ. 2016 Feb;23(2):185-96. doi: 10.1038/cdd.2015.82. Epub 2015 Jun 26.


Cutting Edge: Roles for Batf3-Dependent APCs in the Rejection of Minor Histocompatibility Antigen-Mismatched Grafts.

Atif SM, Nelsen MK, Gibbings SL, Desch AN, Kedl RM, Gill RG, Marrack P, Murphy KM, Grazia TJ, Henson PM, Jakubzick CV.

J Immunol. 2015 Jul 1;195(1):46-50. doi: 10.4049/jimmunol.1500669. Epub 2015 Jun 1.


Conceptual approaches to lung injury and repair.

Zemans RL, Henson PM, Henson JE, Janssen WJ.

Ann Am Thorac Soc. 2015 Mar;12 Suppl 1:S9-15. doi: 10.1513/AnnalsATS.201408-402MG. Review.


Pioglitazone restores phagocyte mitochondrial oxidants and bactericidal capacity in chronic granulomatous disease.

Fernandez-Boyanapalli RF, Frasch SC, Thomas SM, Malcolm KC, Nicks M, Harbeck RJ, Jakubzick CV, Nemenoff R, Henson PM, Holland SM, Bratton DL.

J Allergy Clin Immunol. 2015 Feb;135(2):517-527.e12. doi: 10.1016/j.jaci.2014.10.034. Epub 2014 Dec 10.


Kinetics of the angiogenic response in lung endothelium following acute inflammatory injury with bleomycin.

Yunt ZX, Mohning MP, Barthel L, Kearns MT, Tuder RM, Hyde DM, Henson PM, Janssen WJ.

Exp Lung Res. 2014 Oct;40(8):415-25. doi: 10.3109/01902148.2014.938202. Epub 2014 Aug 25.


Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction.

Desch AN, Gibbings SL, Clambey ET, Janssen WJ, Slansky JE, Kedl RM, Henson PM, Jakubzick C.

Nat Commun. 2014 Aug 19;5:4674. doi: 10.1038/ncomms5674.


Fas ligand-expressing lymphocytes enhance alveolar macrophage apoptosis in the resolution of acute pulmonary inflammation.

Kearns MT, Barthel L, Bednarek JM, Yunt ZX, Henson PM, Janssen WJ.

Am J Physiol Lung Cell Mol Physiol. 2014 Jul 1;307(1):L62-70. doi: 10.1152/ajplung.00273.2013. Epub 2014 May 16.


Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness.

Aschner Y, Khalifah AP, Briones N, Yamashita C, Dolgonos L, Young SK, Campbell MN, Riches DW, Redente EF, Janssen WJ, Henson PM, Sap J, Vacaresse N, Kapus A, McCulloch CA, Zemans RL, Downey GP.

Am J Pathol. 2014 May;184(5):1489-502. doi: 10.1016/j.ajpath.2014.01.016. Epub 2014 Mar 17.


Tumor necrosis factor-α accelerates the resolution of established pulmonary fibrosis in mice by targeting profibrotic lung macrophages.

Redente EF, Keith RC, Janssen W, Henson PM, Ortiz LA, Downey GP, Bratton DL, Riches DW.

Am J Respir Cell Mol Biol. 2014 Apr;50(4):825-37. doi: 10.1165/rcmb.2013-0386OC.


Muc5b is required for airway defence.

Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM.

Nature. 2014 Jan 16;505(7483):412-6. doi: 10.1038/nature12807. Epub 2013 Dec 8.


Circulating hematopoietic progenitor cells are decreased in COPD.

Janssen WJ, Yunt ZX, Muldrow A, Kearns MT, Kloepfer A, Barthel L, Bratton DL, Bowler RP, Henson PM.

COPD. 2014 Jun;11(3):277-89. doi: 10.3109/15412555.2013.841668. Epub 2013 Nov 1.


Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes.

Jakubzick C, Gautier EL, Gibbings SL, Sojka DK, Schlitzer A, Johnson TE, Ivanov S, Duan Q, Bala S, Condon T, van Rooijen N, Grainger JR, Belkaid Y, Ma'ayan A, Riches DW, Yokoyama WM, Ginhoux F, Henson PM, Randolph GJ.

Immunity. 2013 Sep 19;39(3):599-610. doi: 10.1016/j.immuni.2013.08.007. Epub 2013 Sep 5.


Induction of TGF-β1 synthesis by macrophages in response to apoptotic cells requires activation of the scavenger receptor CD36.

Xiong W, Frasch SC, Thomas SM, Bratton DL, Henson PM.

PLoS One. 2013 Aug 2;8(8):e72772. doi: 10.1371/journal.pone.0072772. Print 2013.


Antiinflammatory effects of apoptotic cells.

Henson PM, Bratton DL.

J Clin Invest. 2013 Jul;123(7):2773-4. doi: 10.1172/JCI69344. Epub 2013 Jul 1.


Allergy: airway epithelial Rac1 suppresses allergic inflammation.

Henson PM, Bratton DL.

Curr Biol. 2013 Feb 4;23(3):R104-6. doi: 10.1016/j.cub.2012.12.008.


Neutrophils regulate tissue Neutrophilia in inflammation via the oxidant-modified lipid lysophosphatidylserine.

Frasch SC, Fernandez-Boyanapalli RF, Berry KA, Murphy RC, Leslie CC, Nick JA, Henson PM, Bratton DL.

J Biol Chem. 2013 Feb 15;288(7):4583-93. doi: 10.1074/jbc.M112.438507. Epub 2013 Jan 5.


Pulmonary dendritic cell development and antigen acquisition.

Desch AN, Henson PM, Jakubzick CV.

Immunol Res. 2013 Mar;55(1-3):178-86. doi: 10.1007/s12026-012-8359-6. Review.


Increased lymphatic vessel length is associated with the fibroblast reticulum and disease severity in usual interstitial pneumonia and nonspecific interstitial pneumonia.

Lara AR, Cosgrove GP, Janssen WJ, Huie TJ, Burnham EL, Heinz DE, Curran-Everett D, Sahin H, Schwarz MI, Cool CD, Groshong SD, Geraci MW, Tuder RM, Hyde DM, Henson PM.

Chest. 2012 Dec;142(6):1569-1576. doi: 10.1378/chest.12-0029.


Nitric oxide increases susceptibility of Toll-like receptor-activated macrophages to spreading Listeria monocytogenes.

Cole C, Thomas S, Filak H, Henson PM, Lenz LL.

Immunity. 2012 May 25;36(5):807-20. doi: 10.1016/j.immuni.2012.03.011. Epub 2012 Apr 26. Erratum in: Immunity. 2012 May 25;36(5):885.


Vascular endothelial growth factor enhances macrophage clearance of apoptotic cells.

Kearns MT, Dalal S, Horstmann SA, Richens TR, Tanaka T, Doe JM, Boe DM, Voelkel NF, Taraseviciene-Stewart L, Janssen WJ, Lee CG, Elias JA, Bratton D, Tuder RM, Henson PM, Vandivier RW.

Am J Physiol Lung Cell Mol Physiol. 2012 Apr 1;302(7):L711-8. doi: 10.1152/ajplung.00116.2011. Epub 2012 Feb 3.


Cellular regulation of the inflammatory response.

Janssen WJ, Henson PM.

Toxicol Pathol. 2012;40(2):166-73. doi: 10.1177/0192623311428477. Epub 2011 Nov 16. Review.


Neutrophil transmigration triggers repair of the lung epithelium via beta-catenin signaling.

Zemans RL, Briones N, Campbell M, McClendon J, Young SK, Suzuki T, Yang IV, De Langhe S, Reynolds SD, Mason RJ, Kahn M, Henson PM, Colgan SP, Downey GP.

Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15990-5. doi: 10.1073/pnas.1110144108. Epub 2011 Aug 31.


CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen.

Desch AN, Randolph GJ, Murphy K, Gautier EL, Kedl RM, Lahoud MH, Caminschi I, Shortman K, Henson PM, Jakubzick CV.

J Exp Med. 2011 Aug 29;208(9):1789-97. doi: 10.1084/jem.20110538. Epub 2011 Aug 22.


IgG autoantibodies against deposited C3 inhibit macrophage-mediated apoptotic cell engulfment in systemic autoimmunity.

Kenyon KD, Cole C, Crawford F, Kappler JW, Thurman JM, Bratton DL, Boackle SA, Henson PM.

J Immunol. 2011 Sep 1;187(5):2101-11. doi: 10.4049/jimmunol.1003468. Epub 2011 Aug 3.


Neutrophil clearance: when the party is over, clean-up begins.

Bratton DL, Henson PM.

Trends Immunol. 2011 Aug;32(8):350-7. doi: 10.1016/ Epub 2011 Jul 23. Review.


Age and sex dimorphisms contribute to the severity of bleomycin-induced lung injury and fibrosis.

Redente EF, Jacobsen KM, Solomon JJ, Lara AR, Faubel S, Keith RC, Henson PM, Downey GP, Riches DW.

Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L510-8. doi: 10.1152/ajplung.00122.2011. Epub 2011 Jul 8.


Hemophagocytosis causes a consumptive anemia of inflammation.

Zoller EE, Lykens JE, Terrell CE, Aliberti J, Filipovich AH, Henson PM, Jordan MB.

J Exp Med. 2011 Jun 6;208(6):1203-14. doi: 10.1084/jem.20102538. Epub 2011 May 30.


MALDI imaging MS of phospholipids in the mouse lung.

Berry KA, Li B, Reynolds SD, Barkley RM, Gijón MA, Hankin JA, Henson PM, Murphy RC.

J Lipid Res. 2011 Aug;52(8):1551-60. doi: 10.1194/jlr.M015750. Epub 2011 Apr 20.


Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury.

Janssen WJ, Barthel L, Muldrow A, Oberley-Deegan RE, Kearns MT, Jakubzick C, Henson PM.

Am J Respir Crit Care Med. 2011 Sep 1;184(5):547-60. doi: 10.1164/rccm.201011-1891OC.


Signaling via macrophage G2A enhances efferocytosis of dying neutrophils by augmentation of Rac activity.

Frasch SC, Fernandez-Boyanapalli RF, Berry KZ, Leslie CC, Bonventre JV, Murphy RC, Henson PM, Bratton DL.

J Biol Chem. 2011 Apr 8;286(14):12108-22. doi: 10.1074/jbc.M110.181800. Epub 2011 Feb 4.


Modulation of macrophage efferocytosis in inflammation.

Korns D, Frasch SC, Fernandez-Boyanapalli R, Henson PM, Bratton DL.

Front Immunol. 2011 Nov 8;2:57. doi: 10.3389/fimmu.2011.00057. eCollection 2011.


RhoA-mediated signaling up-regulates hepatocyte growth factor gene and protein expression in response to apoptotic cells.

Park HJ, Choi YH, Cho YJ, Henson PM, Kang JL.

J Leukoc Biol. 2011 Mar;89(3):399-411. doi: 10.1189/jlb.0710414. Epub 2010 Dec 10.


Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-γ in a nitric oxide-dependent manner.

Fernandez-Boyanapalli R, McPhillips KA, Frasch SC, Janssen WJ, Dinauer MC, Riches DW, Henson PM, Byrne A, Bratton DL.

J Immunol. 2010 Oct 1;185(7):4030-41. doi: 10.4049/jimmunol.1001778. Epub 2010 Aug 30.


PPARγ activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease.

Fernandez-Boyanapalli R, Frasch SC, Riches DW, Vandivier RW, Henson PM, Bratton DL.

Blood. 2010 Nov 25;116(22):4512-22. doi: 10.1182/blood-2010-02-272005. Epub 2010 Aug 6.

Supplemental Content

Loading ...
Support Center