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Items: 1 to 50 of 93

1.

Deep learning of spontaneous arousal fluctuations detects early cholinergic defects across neurodevelopmental mouse models and patients.

Artoni P, Piffer A, Vinci V, LeBlanc J, Nelson CA, Hensch TK, Fagiolini M.

Proc Natl Acad Sci U S A. 2019 Jul 22. pii: 201820847. doi: 10.1073/pnas.1820847116. [Epub ahead of print]

PMID:
31332003
2.

Critical Period Regulation by Thyroid Hormones: Potential Mechanisms and Sex-Specific Aspects.

Batista G, Hensch TK.

Front Mol Neurosci. 2019 Apr 5;12:77. doi: 10.3389/fnmol.2019.00077. eCollection 2019.

3.

Impaired cortico-striatal excitatory transmission triggers epilepsy.

Miyamoto H, Tatsukawa T, Shimohata A, Yamagata T, Suzuki T, Amano K, Mazaki E, Raveau M, Ogiwara I, Oba-Asaka A, Hensch TK, Itohara S, Sakimura K, Kobayashi K, Kobayashi K, Yamakawa K.

Nat Commun. 2019 Apr 23;10(1):1917. doi: 10.1038/s41467-019-09954-9.

4.

Deletion of Neuronal GLT-1 in Mice Reveals Its Role in Synaptic Glutamate Homeostasis and Mitochondrial Function.

McNair LF, Andersen JV, Aldana BI, Hohnholt MC, Nissen JD, Sun Y, Fischer KD, Sonnewald U, Nyberg N, Webster SC, Kapur K, Rimmele TS, Barone I, Hawks-Mayer H, Lipton JO, Hodgson NW, Hensch TK, Aoki CJ, Rosenberg PA, Waagepetersen HS.

J Neurosci. 2019 Jun 19;39(25):4847-4863. doi: 10.1523/JNEUROSCI.0894-18.2019. Epub 2019 Mar 29.

PMID:
30926746
5.

Structural maturation of cortical perineuronal nets and their perforating synapses revealed by superresolution imaging.

Sigal YM, Bae H, Bogart LJ, Hensch TK, Zhuang X.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7071-7076. doi: 10.1073/pnas.1817222116. Epub 2019 Mar 19.

PMID:
30890637
6.

Multispectral tracing in densely labeled mouse brain with nTracer.

Roossien DH, Sadis BV, Yan Y, Webb JM, Min LY, Dizaji AS, Bogart LJ, Mazuski C, Huth RS, Stecher JS, Akula S, Shen F, Li Y, Xiao T, Vandenbrink M, Lichtman JW, Hensch TK, Herzog ED, Cai D.

Bioinformatics. 2019 Feb 4. doi: 10.1093/bioinformatics/btz084. [Epub ahead of print]

PMID:
30715234
7.

NMDA 2A receptors in parvalbumin cells mediate sex-specific rapid ketamine response on cortical activity.

Picard N, Takesian AE, Fagiolini M, Hensch TK.

Mol Psychiatry. 2019 Jun;24(6):828-838. doi: 10.1038/s41380-018-0341-9. Epub 2019 Jan 29.

PMID:
30696941
8.

Ceftriaxone Treatment Preserves Cortical Inhibitory Interneuron Function via Transient Salvage of GLT-1 in a Rat Traumatic Brain Injury Model.

Hameed MQ, Hsieh TH, Morales-Quezada L, Lee HHC, Damar U, MacMullin PC, Hensch TK, Rotenberg A.

Cereb Cortex. 2018 Dec 22. doi: 10.1093/cercor/bhy328. [Epub ahead of print]

PMID:
30590449
9.

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

Ogiwara I, Miyamoto H, Tatsukawa T, Yamagata T, Nakayama T, Atapour N, Miura E, Mazaki E, Ernst SJ, Cao D, Ohtani H, Itohara S, Yanagawa Y, Montal M, Yuzaki M, Inoue Y, Hensch TK, Noebels JL, Yamakawa K.

Commun Biol. 2018;1. pii: 96. doi: 10.1038/s42003-018-0099-2. Epub 2018 Jul 19.

10.

Publisher Correction: Inhibitory circuit gating of auditory critical-period plasticity.

Takesian AE, Bogart LJ, Lichtman JW, Hensch TK.

Nat Neurosci. 2018 Oct;21(10):1495. doi: 10.1038/s41593-018-0161-x.

PMID:
29915196
11.

PERSPECTIVE Critical periods in amblyopia-CORRIGENDUM.

Hensch TK, Quinlan EM.

Vis Neurosci. 2018 Jan;35:E024. doi: 10.1017/S0952523818000020. No abstract available.

PMID:
29905127
12.

Critical periods in amblyopia.

Hensch TK, Quinlan EM.

Vis Neurosci. 2018 Jan;35:E014. doi: 10.1017/S0952523817000219. Review. Erratum in: Vis Neurosci. 2018 Jan;35:E024.

13.

Early Seizures Prematurely Unsilence Auditory Synapses to Disrupt Thalamocortical Critical Period Plasticity.

Sun H, Takesian AE, Wang TT, Lippman-Bell JJ, Hensch TK, Jensen FE.

Cell Rep. 2018 May 29;23(9):2533-2540. doi: 10.1016/j.celrep.2018.04.108.

14.

Inhibitory circuit gating of auditory critical-period plasticity.

Takesian AE, Bogart LJ, Lichtman JW, Hensch TK.

Nat Neurosci. 2018 Feb;21(2):218-227. doi: 10.1038/s41593-017-0064-2. Epub 2018 Jan 22. Erratum in: Nat Neurosci. 2018 Oct;21(10):1495.

15.

Social Origins of Developmental Risk for Mental and Physical Illness.

Cameron JL, Eagleson KL, Fox NA, Hensch TK, Levitt P.

J Neurosci. 2017 Nov 8;37(45):10783-10791. doi: 10.1523/JNEUROSCI.1822-17.2017. Review.

16.

Chondroitin Sulfate Is Required for Onset and Offset of Critical Period Plasticity in Visual Cortex.

Hou X, Yoshioka N, Tsukano H, Sakai A, Miyata S, Watanabe Y, Yanagawa Y, Sakimura K, Takeuchi K, Kitagawa H, Hensch TK, Shibuki K, Igarashi M, Sugiyama S.

Sci Rep. 2017 Oct 3;7(1):12646. doi: 10.1038/s41598-017-04007-x.

17.

Genetic Otx2 mis-localization delays critical period plasticity across brain regions.

Lee HHC, Bernard C, Ye Z, Acampora D, Simeone A, Prochiantz A, Di Nardo AA, Hensch TK.

Mol Psychiatry. 2017 May;22(5):785. doi: 10.1038/mp.2017.83. Epub 2017 Apr 4. No abstract available.

PMID:
28373687
18.

Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia.

Steullet P, Cabungcal JH, Coyle J, Didriksen M, Gill K, Grace AA, Hensch TK, LaMantia AS, Lindemann L, Maynard TM, Meyer U, Morishita H, O'Donnell P, Puhl M, Cuenod M, Do KQ.

Mol Psychiatry. 2017 Jul;22(7):936-943. doi: 10.1038/mp.2017.47. Epub 2017 Mar 21.

19.

Genetic Otx2 mis-localization delays critical period plasticity across brain regions.

Lee HHC, Bernard C, Ye Z, Acampora D, Simeone A, Prochiantz A, Di Nardo AA, Hensch TK.

Mol Psychiatry. 2017 May;22(5):680-688. doi: 10.1038/mp.2017.1. Epub 2017 Feb 14. Erratum in: Mol Psychiatry. 2017 May;22(5):785.

20.

Trajectory of Parvalbumin Cell Impairment and Loss of Cortical Inhibition in Traumatic Brain Injury.

Hsieh TH, Lee HHC, Hameed MQ, Pascual-Leone A, Hensch TK, Rotenberg A.

Cereb Cortex. 2017 Dec 1;27(12):5509-5524. doi: 10.1093/cercor/bhw318.

21.

THE POWER OF THE INFANT BRAIN.

Hensch TK.

Sci Am. 2016 Feb;314(2):64-9. No abstract available.

PMID:
26930830
22.

Restoration of Visual Function by Enhancing Conduction in Regenerated Axons.

Bei F, Lee HHC, Liu X, Gunner G, Jin H, Ma L, Wang C, Hou L, Hensch TK, Frank E, Sanes JR, Chen C, Fagiolini M, He Z.

Cell. 2016 Jan 14;164(1-2):219-232. doi: 10.1016/j.cell.2015.11.036.

23.

Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plasticity by HDAC inhibitors.

Lennartsson A, Arner E, Fagiolini M, Saxena A, Andersson R, Takahashi H, Noro Y, Sng J, Sandelin A, Hensch TK, Carninci P.

Epigenetics Chromatin. 2015 Dec 14;8:55. doi: 10.1186/s13072-015-0043-3. eCollection 2015.

24.

Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.

Takei Y, Kikkawa YS, Atapour N, Hensch TK, Hirokawa N.

J Neurosci. 2015 Nov 25;35(47):15539-54. doi: 10.1523/JNEUROSCI.2671-15.2015.

25.

Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons.

Ye Z, Mostajo-Radji MA, Brown JR, Rouaux C, Tomassy GS, Hensch TK, Arlotta P.

Neuron. 2015 Nov 4;88(3):475-83. doi: 10.1016/j.neuron.2015.10.006.

26.

Cell-Specific Regulation of N-Methyl-D-Aspartate Receptor Maturation by Mecp2 in Cortical Circuits.

Mierau SB, Patrizi A, Hensch TK, Fagiolini M.

Biol Psychiatry. 2016 May 1;79(9):746-754. doi: 10.1016/j.biopsych.2015.05.018. Epub 2015 Jun 5.

27.

Targeting Oxidative Stress and Aberrant Critical Period Plasticity in the Developmental Trajectory to Schizophrenia.

Do KQ, Cuenod M, Hensch TK.

Schizophr Bull. 2015 Jul;41(4):835-46. doi: 10.1093/schbul/sbv065. Epub 2015 Jun 1. Review.

28.

Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates.

Gurnot C, Martin-Subero I, Mah SM, Weikum W, Goodman SJ, Brain U, Werker JF, Kobor MS, Esteller M, Oberlander TF, Hensch TK.

Epigenetics. 2015;10(5):361-72. doi: 10.1080/15592294.2015.1026031. Epub 2015 Apr 18.

29.

Clock genes control cortical critical period timing.

Kobayashi Y, Ye Z, Hensch TK.

Neuron. 2015 Apr 8;86(1):264-75. doi: 10.1016/j.neuron.2015.02.036. Epub 2015 Mar 19.

30.

Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons.

Morishita H, Cabungcal JH, Chen Y, Do KQ, Hensch TK.

Biol Psychiatry. 2015 Sep 15;78(6):396-402. doi: 10.1016/j.biopsych.2014.12.026. Epub 2015 Jan 24.

31.

Critical periods in speech perception: new directions.

Werker JF, Hensch TK.

Annu Rev Psychol. 2015 Jan 3;66:173-96. doi: 10.1146/annurev-psych-010814-015104. Epub 2014 Sep 17. Review.

PMID:
25251488
32.

Sensory integration in mouse insular cortex reflects GABA circuit maturation.

Gogolla N, Takesian AE, Feng G, Fagiolini M, Hensch TK.

Neuron. 2014 Aug 20;83(4):894-905. doi: 10.1016/j.neuron.2014.06.033. Epub 2014 Jul 31.

33.

Bistable parvalbumin circuits pivotal for brain plasticity.

Hensch TK.

Cell. 2014 Jan 16;156(1-2):17-9. doi: 10.1016/j.cell.2013.12.034.

34.

Valproate reopens critical-period learning of absolute pitch.

Gervain J, Vines BW, Chen LM, Seo RJ, Hensch TK, Werker JF, Young AH.

Front Syst Neurosci. 2013 Dec 3;7:102. doi: 10.3389/fnsys.2013.00102. eCollection 2013.

35.

Balancing plasticity/stability across brain development.

Takesian AE, Hensch TK.

Prog Brain Res. 2013;207:3-34. doi: 10.1016/B978-0-444-63327-9.00001-1. Review.

PMID:
24309249
36.

Visual acuity development and plasticity in the absence of sensory experience.

Kang E, Durand S, LeBlanc JJ, Hensch TK, Chen C, Fagiolini M.

J Neurosci. 2013 Nov 6;33(45):17789-96. doi: 10.1523/JNEUROSCI.1500-13.2013.

37.

Germline recombination by conditional gene targeting with Parvalbumin-Cre lines.

Kobayashi Y, Hensch TK.

Front Neural Circuits. 2013 Oct 16;7:168. doi: 10.3389/fncir.2013.00168. eCollection 2013. No abstract available.

38.

IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice.

Hisatsune C, Miyamoto H, Hirono M, Yamaguchi N, Sugawara T, Ogawa N, Ebisui E, Ohshima T, Yamada M, Hensch TK, Hattori M, Mikoshiba K.

Front Neural Circuits. 2013 Oct 4;7:156. doi: 10.3389/fncir.2013.00156. eCollection 2013.

39.

A theory of the transition to critical period plasticity: inhibition selectively suppresses spontaneous activity.

Toyoizumi T, Miyamoto H, Yazaki-Sugiyama Y, Atapour N, Hensch TK, Miller KD.

Neuron. 2013 Oct 2;80(1):51-63. doi: 10.1016/j.neuron.2013.07.022. Epub 2013 Oct 2.

40.

DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease.

Sanchez-Mut JV, Aso E, Panayotis N, Lott I, Dierssen M, Rabano A, Urdinguio RG, Fernandez AF, Astudillo A, Martin-Subero JI, Balint B, Fraga MF, Gomez A, Gurnot C, Roux JC, Avila J, Hensch TK, Ferrer I, Esteller M.

Brain. 2013 Oct;136(Pt 10):3018-27. doi: 10.1093/brain/awt237. Epub 2013 Sep 11.

41.

Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome.

Ogiwara I, Iwasato T, Miyamoto H, Iwata R, Yamagata T, Mazaki E, Yanagawa Y, Tamamaki N, Hensch TK, Itohara S, Yamakawa K.

Hum Mol Genet. 2013 Dec 1;22(23):4784-804. doi: 10.1093/hmg/ddt331. Epub 2013 Aug 6.

42.

Choroid-plexus-derived Otx2 homeoprotein constrains adult cortical plasticity.

Spatazza J, Lee HH, Di Nardo AA, Tibaldi L, Joliot A, Hensch TK, Prochiantz A.

Cell Rep. 2013 Jun 27;3(6):1815-23. doi: 10.1016/j.celrep.2013.05.014. Epub 2013 Jun 13.

43.

Perineuronal nets protect fast-spiking interneurons against oxidative stress.

Cabungcal JH, Steullet P, Morishita H, Kraftsik R, Cuenod M, Hensch TK, Do KQ.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):9130-5. doi: 10.1073/pnas.1300454110. Epub 2013 May 13.

44.

Re-opening Windows: Manipulating Critical Periods for Brain Development.

Hensch TK, Bilimoria PM.

Cerebrum. 2012 Jul;2012:11. Epub 2012 Aug 29.

45.

NMDA receptor regulation prevents regression of visual cortical function in the absence of Mecp2.

Durand S, Patrizi A, Quast KB, Hachigian L, Pavlyuk R, Saxena A, Carninci P, Hensch TK, Fagiolini M.

Neuron. 2012 Dec 20;76(6):1078-90. doi: 10.1016/j.neuron.2012.12.004.

46.

Serotonergic integration of circadian clock and ultradian sleep-wake cycles.

Miyamoto H, Nakamaru-Ogiso E, Hamada K, Hensch TK.

J Neurosci. 2012 Oct 17;32(42):14794-803. doi: 10.1523/JNEUROSCI.0793-12.2012.

47.

Critical period for acoustic preference in mice.

Yang EJ, Lin EW, Hensch TK.

Proc Natl Acad Sci U S A. 2012 Oct 16;109 Suppl 2:17213-20. doi: 10.1073/pnas.1200705109. Epub 2012 Oct 8.

48.

Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception.

Weikum WM, Oberlander TF, Hensch TK, Werker JF.

Proc Natl Acad Sci U S A. 2012 Oct 16;109 Suppl 2:17221-7. doi: 10.1073/pnas.1121263109. Epub 2012 Oct 8.

49.

A mouse model for too much TV?

Bilimoria PM, Hensch TK, Bavelier D.

Trends Cogn Sci. 2012 Nov;16(11):529-31. doi: 10.1016/j.tics.2012.09.001. Epub 2012 Sep 19.

50.

Mouse with Nav1.1 haploinsufficiency, a model for Dravet syndrome, exhibits lowered sociability and learning impairment.

Ito S, Ogiwara I, Yamada K, Miyamoto H, Hensch TK, Osawa M, Yamakawa K.

Neurobiol Dis. 2013 Jan;49:29-40. doi: 10.1016/j.nbd.2012.08.003. Epub 2012 Aug 16.

PMID:
22986304

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