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Items: 1 to 50 of 79

1.

The many meanings of autism: conceptual and ethical reflections.

Hens K.

Dev Med Child Neurol. 2019 Jun 17. doi: 10.1111/dmcn.14278. [Epub ahead of print] Review.

PMID:
31209874
2.

Physician View and Experience of the Diagnosis of Autism Spectrum Disorder in Young Children.

Jacobs D, Steyaert J, Dierickx K, Hens K.

Front Psychiatry. 2019 May 28;10:372. doi: 10.3389/fpsyt.2019.00372. eCollection 2019.

3.

A Comprehensive Drosophila melanogaster Transcription Factor Interactome.

Shokri L, Inukai S, Hafner A, Weinand K, Hens K, Vedenko A, Gisselbrecht SS, Dainese R, Bischof J, Furger E, Feuz JD, Basler K, Deplancke B, Bulyk ML.

Cell Rep. 2019 Apr 16;27(3):955-970.e7. doi: 10.1016/j.celrep.2019.03.071.

4.

Conceptualizing neurodevelopmental disorders as networks: Promises and challenges.

Hens K, Evers K, Wagemans J.

Behav Brain Sci. 2019 Jan;42:e10. doi: 10.1017/S0140525X18001218.

PMID:
30940239
5.

Blurring boundaries. Interviews with PGT couples about comprehensive chromosome screening.

Hens K, Bonduelle M, de Die-Smulders C, Liebaers I.

Eur J Med Genet. 2018 Dec 17. pii: S1769-7212(18)30567-6. doi: 10.1016/j.ejmg.2018.12.009. [Epub ahead of print]

PMID:
30572173
6.

Implications of an Autism Spectrum Disorder Diagnosis: An Interview Study of How Physicians Experience the Diagnosis in a Young Child.

Jacobs D, Steyaert J, Dierickx K, Hens K.

J Clin Med. 2018 Oct 12;7(10). pii: E348. doi: 10.3390/jcm7100348.

7.

Sugar Promotes Feeding in Flies via the Serine Protease Homolog scarface.

Prasad N, Hens K.

Cell Rep. 2018 Sep 18;24(12):3194-3206.e4. doi: 10.1016/j.celrep.2018.08.059.

8.

[Biology and context. Experiences of adults diagnosed with autism].

Hens K, Langenberg R.

Tijdschr Psychiatr. 2018;60(8):536-543. Dutch.

9.

The ethics of patenting autism genes.

Hens K, Noens I, Peeters H, Steyaert J.

Nat Rev Genet. 2018 May;19(5):247-248. doi: 10.1038/nrg.2018.17. Epub 2018 Mar 26. No abstract available.

PMID:
29576616
10.
11.

Hippo, TGF-β, and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila enterocytes upon bacterial infection.

Houtz P, Bonfini A, Liu X, Revah J, Guillou A, Poidevin M, Hens K, Huang HY, Deplancke B, Tsai YC, Buchon N.

PLoS Genet. 2017 Nov 6;13(11):e1007091. doi: 10.1371/journal.pgen.1007091. eCollection 2017 Nov.

12.

Recommendations for collaborative paediatric research including biobanking in Europe: a Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) initiative.

Kuemmerle-Deschner JB, Hansmann S, Wulffraat NM, Vastert SJ, Hens K, Anton J, Avcin T, Martini A, Koné-Paut I, Uziel Y, Ravelli A, Wouters C, Shaw D, Özen S, Eikelberg A, Prakken BJ, Ruperto N, Horneff G, Constantin T, Beresford MW, Sikken M, Foster HE, Haug I, Schuller S, Jägle C, Benseler SM.

Ann Rheum Dis. 2018 Mar;77(3):319-327. doi: 10.1136/annrheumdis-2017-211904. Epub 2017 Oct 11. Review.

PMID:
29021237
13.

The Zic family homologue Odd-paired regulates Alk expression in Drosophila.

Mendoza-García P, Hugosson F, Fallah M, Higgins ML, Iwasaki Y, Pfeifer K, Wolfstetter G, Varshney G, Popichenko D, Gergen JP, Hens K, Deplancke B, Palmer RH.

PLoS Genet. 2017 Apr 3;13(4):e1006617. doi: 10.1371/journal.pgen.1006617. eCollection 2017 Apr.

14.

Genetic testing and counseling in the case of an autism diagnosis: A caregivers perspective.

Hens K, Peeters H, Dierickx K.

Eur J Med Genet. 2016 Sep;59(9):452-8. doi: 10.1016/j.ejmg.2016.08.007. Epub 2016 Aug 17.

PMID:
27544064
15.

Potential Direct Regulators of the Drosophila yellow Gene Identified by Yeast One-Hybrid and RNAi Screens.

Kalay G, Lusk R, Dome M, Hens K, Deplancke B, Wittkopp PJ.

G3 (Bethesda). 2016 Oct 13;6(10):3419-3430. doi: 10.1534/g3.116.032607.

16.

Using "big data" to describe the effect of seasonal variation in thyroid-stimulating hormone.

De Grande LA, Goossens K, Van Uytfanghe K, Halsall I, Yoshimura Noh J, Hens K, Thienpont LM.

Clin Chem Lab Med. 2017 Feb 1;55(2):e34-e36. doi: 10.1515/cclm-2016-0500. No abstract available.

PMID:
27447241
17.

The ethics of complexity. Genetics and autism, a literature review.

Hens K, Peeters H, Dierickx K.

Am J Med Genet B Neuropsychiatr Genet. 2016 Apr;171B(3):305-16. doi: 10.1002/ajmg.b.32432. Epub 2016 Feb 12. Review.

PMID:
26870917
18.

Mood stabilizing drugs regulate transcription of immune, neuronal and metabolic pathway genes in Drosophila.

Herteleer L, Zwarts L, Hens K, Forero D, Del-Favero J, Callaerts P.

Psychopharmacology (Berl). 2016 May;233(9):1751-62. doi: 10.1007/s00213-016-4223-z. Epub 2016 Feb 6.

PMID:
26852229
19.

Shooting a moving target. Researching autism genes: An interview study with professionals.

Hens K, Peeters H, Dierickx K.

Eur J Med Genet. 2016 Jan;59(1):32-8. doi: 10.1016/j.ejmg.2015.12.009. Epub 2015 Dec 23.

PMID:
26721322
20.

Ethical issues surrounding the provider initiated opt--Out prenatal HIV screening practice in Sub-Saharan Africa: a literature review.

Bain LE, Dierickx K, Hens K.

BMC Med Ethics. 2015 Oct 24;16(1):73. doi: 10.1186/s12910-015-0068-y. Review.

21.

"What about FH of my child?" parents' opinion on family history collection in preventive primary pediatric care.

Syurina EV, Gerritsen AJ, Hens K, Feron FJ.

Per Med. 2015 Aug;12(4):327-337. doi: 10.2217/pme.15.9.

PMID:
29771656
22.

Double Trouble: Preventive Genomic Sequencing and the Case of Minors.

Hens K, Dierickx K.

Am J Bioeth. 2015;15(7):30-1. doi: 10.1080/15265161.2015.1039723. No abstract available.

PMID:
26147262
23.

The diversity of genetic perfection.

Mertes H, Hens K.

Am J Bioeth. 2015;15(6):34-6. doi: 10.1080/15265161.2015.1028664. No abstract available.

PMID:
26030495
24.

A leap of faith? An interview study with professionals on the use of mitochondrial replacement to avoid transfer of mitochondrial diseases.

Hens K, Dondorp W, de Wert G.

Hum Reprod. 2015 May;30(5):1256-62. doi: 10.1093/humrep/dev056. Epub 2015 Mar 18.

PMID:
25790821
25.

Conservation of transcription factor binding specificities across 600 million years of bilateria evolution.

Nitta KR, Jolma A, Yin Y, Morgunova E, Kivioja T, Akhtar J, Hens K, Toivonen J, Deplancke B, Furlong EE, Taipale J.

Elife. 2015 Mar 17;4. doi: 10.7554/eLife.04837.

26.

A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development.

Schertel C, Albarca M, Rockel-Bauer C, Kelley NW, Bischof J, Hens K, van Nimwegen E, Basler K, Deplancke B.

Genome Res. 2015 Apr;25(4):514-23. doi: 10.1101/gr.181305.114. Epub 2015 Jan 7.

27.

JNJ-40255293, a novel adenosine A2A/A1 antagonist with efficacy in preclinical models of Parkinson's disease.

Atack JR, Shook BC, Rassnick S, Jackson PF, Rhodes K, Drinkenburg WH, Ahnaou A, Te Riele P, Langlois X, Hrupka B, De Haes P, Hendrickx H, Aerts N, Hens K, Wellens A, Vermeire J, Megens AA.

ACS Chem Neurosci. 2014 Oct 15;5(10):1005-19. doi: 10.1021/cn5001606. Epub 2014 Sep 24.

PMID:
25203719
28.

Preserving children's fertility: two tales about children's right to an open future and the margins of parental obligations.

Cutas D, Hens K.

Med Health Care Philos. 2015 May;18(2):253-60. doi: 10.1007/s11019-014-9596-3.

PMID:
25189425
29.

Sigma metrics used to assess analytical quality of clinical chemistry assays: importance of the allowable total error (TEa) target.

Hens K, Berth M, Armbruster D, Westgard S.

Clin Chem Lab Med. 2014 Jul;52(7):973-80. doi: 10.1515/cclm-2013-1090.

PMID:
24615486
30.

In vitro screening of embryos by whole-genome sequencing: now, in the future or never?

Winand R, Hens K, Dondorp W, de Wert G, Moreau Y, Vermeesch JR, Liebaers I, Aerts J.

Hum Reprod. 2014 Apr;29(4):842-51. doi: 10.1093/humrep/deu005. Epub 2014 Feb 2.

PMID:
24491297
31.

mGlu(2) receptor-mediated modulation of conditioned avoidance behavior in rats.

Megens AA, Hendrickx HM, Hens KA, Talloen WJ, Lavreysen H.

Eur J Pharmacol. 2014 Mar 15;727:130-9. doi: 10.1016/j.ejphar.2014.01.044. Epub 2014 Jan 30.

PMID:
24486391
32.

Pharmacology of JNJ-42314415, a centrally active phosphodiesterase 10A (PDE10A) inhibitor: a comparison of PDE10A inhibitors with D2 receptor blockers as potential antipsychotic drugs.

Megens AA, Hendrickx HM, Hens KA, Fonteyn I, Langlois X, Lenaerts I, Somers MV, de Boer P, Vanhoof G.

J Pharmacol Exp Ther. 2014 Apr;349(1):138-54. doi: 10.1124/jpet.113.211904. Epub 2014 Jan 13.

PMID:
24421319
33.

Neprilysins: an evolutionarily conserved family of metalloproteases that play important roles in reproduction in Drosophila.

Sitnik JL, Francis C, Hens K, Huybrechts R, Wolfner MF, Callaerts P.

Genetics. 2014 Mar;196(3):781-97. doi: 10.1534/genetics.113.160945. Epub 2014 Jan 6.

34.

A yeast one-hybrid and microfluidics-based pipeline to map mammalian gene regulatory networks.

Gubelmann C, Waszak SM, Isakova A, Holcombe W, Hens K, Iagovitina A, Feuz JD, Raghav SK, Simicevic J, Deplancke B.

Mol Syst Biol. 2013 Aug 6;9:682. doi: 10.1038/msb.2013.38.

35.

To transfer or not to transfer: the case of comprehensive chromosome screening of the in vitro embryo.

Hens K.

Health Care Anal. 2015 Jun;23(2):197-206. doi: 10.1007/s10728-013-0259-y.

PMID:
23907565
36.

Dynamics and ethics of comprehensive preimplantation genetic testing: a review of the challenges.

Hens K, Dondorp W, Handyside AH, Harper J, Newson AJ, Pennings G, Rehmann-Sutter C, de Wert G.

Hum Reprod Update. 2013 Jul-Aug;19(4):366-75. doi: 10.1093/humupd/dmt009. Epub 2013 Mar 6. Review.

PMID:
23466750
37.

Comprehensive embryo testing. Experts' opinions regarding future directions: an expert panel study on comprehensive embryo testing.

Hens K, Dondorp WJ, Geraedts JP, de Wert GM.

Hum Reprod. 2013 May;28(5):1418-25. doi: 10.1093/humrep/det018. Epub 2013 Feb 15.

PMID:
23416277
38.

iSLIM: a comprehensive approach to mapping and characterizing gene regulatory networks.

Rockel S, Geertz M, Hens K, Deplancke B, Maerkl SJ.

Nucleic Acids Res. 2013 Feb 1;41(4):e52. doi: 10.1093/nar/gks1323. Epub 2012 Dec 20.

39.

Genomic variation and its impact on gene expression in Drosophila melanogaster.

Massouras A, Waszak SM, Albarca-Aguilera M, Hens K, Holcombe W, Ayroles JF, Dermitzakis ET, Stone EA, Jensen JD, Mackay TF, Deplancke B.

PLoS Genet. 2012;8(11):e1003055. doi: 10.1371/journal.pgen.1003055. Epub 2012 Nov 15.

40.

Embryos without secrets: an expert panel study on comprehensive embryo testing and the responsibility of the clinician.

Hens K, Dondorp W, de Wert G.

Eur J Med Genet. 2013 Feb;56(2):67-71. doi: 10.1016/j.ejmg.2012.10.013. Epub 2012 Nov 3.

PMID:
23131419
41.

Comprehensive pre-implantation genetic screening: ethical reflection urgently needed.

Hens K, Dondorp W, Geraedts J, de Wert G.

Nat Rev Genet. 2012 Oct;13(10):676-7. doi: 10.1038/nrg3334. Epub 2012 Sep 4. No abstract available.

PMID:
22945395
42.

Topology and dynamics of the zebrafish segmentation clock core circuit.

Schröter C, Ares S, Morelli LG, Isakova A, Hens K, Soroldoni D, Gajewski M, Jülicher F, Maerkl SJ, Deplancke B, Oates AC.

PLoS Biol. 2012;10(7):e1001364. doi: 10.1371/journal.pbio.1001364. Epub 2012 Jul 24.

43.

Developing a policy for paediatric biobanks: principles for good practice.

Hens K, Van El CE, Borry P, Cambon-Thomsen A, Cornel MC, Forzano F, Lucassen A, Patch C, Tranebjaerg L, Vermeulen E, Salvaterra E, Tibben A, Dierickx K; PPPC of the European Society of Human Genetics.

Eur J Hum Genet. 2013 Jan;21(1):2-7. doi: 10.1038/ejhg.2012.99. Epub 2012 Jun 20.

44.

Automated protein-DNA interaction screening of Drosophila regulatory elements.

Hens K, Feuz JD, Isakova A, Iagovitina A, Massouras A, Bryois J, Callaerts P, Celniker SE, Deplancke B.

Nat Methods. 2011 Oct 30;8(12):1065-70. doi: 10.1038/nmeth.1763.

45.

A high-throughput gateway-compatible yeast one-hybrid screen to detect protein-DNA interactions.

Hens K, Feuz JD, Deplancke B.

Methods Mol Biol. 2012;786:335-55. doi: 10.1007/978-1-61779-292-2_20.

PMID:
21938636
46.

GETPrime: a gene- or transcript-specific primer database for quantitative real-time PCR.

Gubelmann C, Gattiker A, Massouras A, Hens K, David F, Decouttere F, Rougemont J, Deplancke B.

Database (Oxford). 2011 Sep 14;2011:bar040. doi: 10.1093/database/bar040. Print 2011.

47.

Children and biobanks: a review of the ethical and legal discussion.

Hens K, Lévesque E, Dierickx K.

Hum Genet. 2011 Sep;130(3):403-13. doi: 10.1007/s00439-011-1031-8. Epub 2011 Jun 10. Review.

PMID:
21660506
48.

Children, biobanks and the scope of parental consent.

Hens K, Cassiman JJ, Nys H, Dierickx K.

Eur J Hum Genet. 2011 Jul;19(7):735-9. doi: 10.1038/ejhg.2011.29. Epub 2011 Mar 9.

49.

Risks, benefits, solidarity: a framework for the participation of children in genetic biobank research.

Hens K, Nys H, Cassiman JJ, Dierickx K.

J Pediatr. 2011 May;158(5):842-8. doi: 10.1016/j.jpeds.2010.12.036. Epub 2011 Feb 24. Review. No abstract available.

PMID:
21349539
50.

The return of individual research findings in paediatric genetic research.

Hens K, Nys H, Cassiman JJ, Dierickx K.

J Med Ethics. 2011 Mar;37(3):179-83. doi: 10.1136/jme.2010.037473. Epub 2010 Nov 8.

PMID:
21059631

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